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Volumn 135, Issue 11, 2012, Pages 3298-3310

Interleukin 6-preconditioned neural stem cells reduce ischaemic injury in stroke mice

Author keywords

angiogenesis; cytokine preconditioning; ischaemic stroke; oxidative stress; transplantation

Indexed keywords

INTERLEUKIN 6; MANGANESE SUPEROXIDE DISMUTASE; RNA; STAT3 PROTEIN; VASCULOTROPIN;

EID: 84870203833     PISSN: 00068950     EISSN: 14602156     Source Type: Journal    
DOI: 10.1093/brain/aws259     Document Type: Article
Times cited : (82)

References (44)
  • 1
    • 79957814267 scopus 로고    scopus 로고
    • Human neural stem cells enhance structural plasticity and axonal transport in the ischaemic brain
    • Andres RH, Horie N, Slikker W, Keren-Gill H, Zhan K, Sun G, et al. Human neural stem cells enhance structural plasticity and axonal transport in the ischaemic brain. Brain 2011; 134: 1777-89.
    • (2011) Brain , vol.134 , pp. 1777-1778
    • Andres, R.H.1    Horie, N.2    Slikker, W.3    Keren-Gill, H.4    Zhan, K.5    Sun, G.6
  • 2
    • 67749143855 scopus 로고    scopus 로고
    • Delayed post-ischaemic neuroprotection following systemic neural stem cell transplantation involves multiple mechanisms
    • Bacigaluppi M, Pluchino S, Jametti LP, Kilic E, Kilic Ü, Salani G, et al. Delayed post-ischaemic neuroprotection following systemic neural stem cell transplantation involves multiple mechanisms. Brain 2009; 132: 2239-51.
    • (2009) Brain , vol.132 , pp. 2239-2235
    • Bacigaluppi, M.1    Pluchino, S.2    Jametti, L.P.3    Kilic, E.4    Kilic, U.5    Salani, G.6
  • 5
    • 72749121996 scopus 로고    scopus 로고
    • Optimizing the success of cell transplantation therapy for stroke
    • Bliss TM, Andres RH, Steinberg GK. Optimizing the success of cell transplantation therapy for stroke. Neurobiol Dis 2010; 37: 275-83.
    • (2010) Neurobiol Dis , vol.37 , pp. 275-278
    • Bliss, T.M.1    Andres, R.H.2    Steinberg, G.K.3
  • 7
    • 0030708523 scopus 로고    scopus 로고
    • Regulation of gliogenesis in the central nervous system by the jak-stat signaling pathway
    • Bonni A, Sun Y, Nadal-Vicens M, Bhatt A, Frank DA, Rozovsky I, et al. Regulation of gliogenesis in the central nervous system by the JAK-STAT signaling pathway. Science 1997; 278: 477-83.
    • (1997) Science , vol.278 , pp. 477-478
    • Bonni, A.1    Sun, Y.2    Nadal-Vicens, M.3    Bhatt, A.4    Frank, D.A.5    Rozovsky, I.6
  • 8
    • 0036469065 scopus 로고    scopus 로고
    • Transcription: Signal transduction and the control of gene expression
    • DOI 10.1126/science.1066355
    • Brivanlou AH, Darnell JE Jr. Signal transduction and the control of gene expression. Science 2002; 295: 813-8. (Pubitemid 34118354)
    • (2002) Science , vol.295 , Issue.5556 , pp. 813-818
    • Brivanlou, A.H.1    Darnell Jr., J.E.2
  • 9
    • 0029888311 scopus 로고    scopus 로고
    • Role of oxidants in ischemic brain damage
    • Chan PH. Role of oxidants in ischemic brain damage. Stroke 1996; 27: 1124-9. (Pubitemid 26177617)
    • (1996) Stroke , vol.27 , Issue.6 , pp. 1124-1129
    • Chan, P.H.1
  • 10
    • 12844260208 scopus 로고    scopus 로고
    • Atorvastatin induction of vegf and bdnf promotes brain plasticity after stroke in mice
    • Chen J, Zhang C, Jiang H, Li Y, Zhang L, Robin A, et al. Atorvastatin induction of VEGF and BDNF promotes brain plasticity after stroke in mice. J Cereb Blood Flow Metab 2005; 25: 281-90.
    • (2005) J Cereb Blood Flow Metab , vol.25 , pp. 281-289
    • Chen, J.1    Zhang, C.2    Jiang, H.3    Li, Y.4    Zhang, L.5    Robin, A.6
  • 11
    • 0037418936 scopus 로고    scopus 로고
    • Intravenous administration of human bone marrow stromal cells induces angiogenesis in the ischemic boundary zone after stroke in rats
    • DOI 10.1161/01.RES.0000063425.51108.8D
    • Chen J, Zhang ZG, Li Y, Wang L, Xu YX, Gautam SC, et al. Intravenous administration of human bone marrow stromal cells induces angiogenesis in the ischemic boundary zone after stroke in rats. Circ Res 2003; 92: 692-9. (Pubitemid 36417705)
    • (2003) Circulation Research , vol.92 , Issue.6 , pp. 692-699
    • Chen, J.1    Zhang, Z.G.2    Li, Y.3    Wang, L.4    Xu, Y.X.5    Gautam, S.C.6    Lu, M.7    Zhu, Z.8    Chopp, M.9
  • 12
    • 77951758771 scopus 로고    scopus 로고
    • Endothelial progenitor cell transplantation improves long-Term stroke outcome in mice
    • Fan Y, Shen F, Frenzel T, Zhu W, Ye J, Liu J, et al. Endothelial progenitor cell transplantation improves long-Term stroke outcome in mice. Ann Neurol 2010; 67: 488-97.
    • (2010) Ann Neurol , vol.67 , pp. 488-489
    • Fan, Y.1    Shen, F.2    Frenzel, T.3    Zhu, W.4    Ye, J.5    Liu, J.6
  • 13
    • 0033135367 scopus 로고    scopus 로고
    • Manganese superoxide dismutase mediates the early release of mitochondrial cytochrome c and subsequent dna fragmentation after permanent focal cerebral ischemia in mice
    • Fujimura M, Morita-Fujimura Y, Kawase M, Copin J-C, Calagui B, Epstein CJ, et al. Manganese superoxide dismutase mediates the early release of mitochondrial cytochrome c and subsequent DNA fragmentation after permanent focal cerebral ischemia in mice. J Neurosci 1999; 19: 3414-22.
    • (1999) J Neurosci , vol.19 , pp. 3414-3412
    • Fujimura, M.1    Morita-Fujimura, Y.2    Kawase, M.3    Copin, J.-C.4    Calagui, B.5    Epstein, C.J.6
  • 15
    • 59149083670 scopus 로고    scopus 로고
    • Transplantation of human embryonic stem cell-derived neural precursor cells and enriched environment after cortical stroke in rats: Cell survival and functional recovery
    • Hicks AU, Lappalainen RS, Narkilahti S, Suuronen R, Corbett D, Sivenius J, et al. Transplantation of human embryonic stem cell-derived neural precursor cells and enriched environment after cortical stroke in rats: cell survival and functional recovery. Eur J Neurosci 2009; 29: 562-74.
    • (2009) Eur J Neurosci , vol.29 , pp. 562-567
    • Hicks, A.U.1    Lappalainen, R.S.2    Narkilahti, S.3    Suuronen, R.4    Corbett, D.5    Sivenius, J.6
  • 16
    • 0034658541 scopus 로고    scopus 로고
    • Roles of stat3 in mediating the cell growth, differentiation and survival signals relayed through the il-6 family of cytokine receptors
    • Hirano T, Ishihara K, Hibi M. Roles of STAT3 in mediating the cell growth, differentiation and survival signals relayed through the IL-6 family of cytokine receptors. Oncogene 2000; 19: 2548-56.
    • (2000) Oncogene , vol.19 , pp. 2548-2545
    • Hirano, T.1    Ishihara, K.2    Hibi, M.3
  • 17
    • 79952164901 scopus 로고    scopus 로고
    • Transplanted stem cell-secreted vascular endothelial growth factor effects poststroke recovery, inflammation, and vascular repair
    • Horie N, Pereira MP, Niizuma K, Sun G, Keren-Gill H, Encarnacion A, et al. Transplanted stem cell-secreted vascular endothelial growth factor effects poststroke recovery, inflammation, and vascular repair. Stem Cells 2011; 29: 274-85.
    • (2011) Stem Cells , vol.29 , pp. 274-278
    • Horie, N.1    Pereira, M.P.2    Niizuma, K.3    Sun, G.4    Keren-Gill, H.5    Encarnacion, A.6
  • 18
    • 55049090532 scopus 로고    scopus 로고
    • Effect of inflammatory cytokines on major histocompatibility complex expression and differentiation of human neural stem/progenitor cells
    • Johansson S, Price J, Modo M. Effect of inflammatory cytokines on major histocompatibility complex expression and differentiation of human neural stem/progenitor cells. Stem Cells 2008; 26: 2444-54.
    • (2008) Stem Cells , vol.26 , pp. 2444-2445
    • Johansson, S.1    Price, J.2    Modo, M.3
  • 19
    • 77954762962 scopus 로고    scopus 로고
    • Preventing adverse remodeling and rupture during healing after myocardial infarction in mice and humans
    • Jugdutt BI. Preventing adverse remodeling and rupture during healing after myocardial infarction in mice and humans. Circulation 2010; 122: 103-5.
    • (2010) Circulation , vol.122 , pp. 103-105
    • Jugdutt, B.I.1
  • 20
    • 84856209632 scopus 로고    scopus 로고
    • Neuroprotection by interleukin-6 is mediated by signal transducer and activator of transcription 3 and antioxidative signaling in ischemic stroke
    • Jung JE, Kim GS, Chan PH. Neuroprotection by interleukin-6 is mediated by signal transducer and activator of transcription 3 and antioxidative signaling in ischemic stroke. Stroke 2011; 42: 3574-9.
    • (2011) Stroke , vol.42 , pp. 3574-3579
    • Jung, J.E.1    Kim, G.S.2    Chan, P.H.3
  • 21
    • 66149171367 scopus 로고    scopus 로고
    • Regulation of mn-superoxide dismutase activity and neuroprotection by stat3 in mice after cerebral ischemia
    • Jung JE, Kim GS, Narasimhan P, Song YS, Chan PH. Regulation of Mn-superoxide dismutase activity and neuroprotection by STAT3 in mice after cerebral ischemia. J Neurosci 2009; 29: 7003-14.
    • (2009) J Neurosci , vol.29 , pp. 7003-7001
    • Jung, J.E.1    Kim, G.S.2    Narasimhan, P.3    Song, Y.S.4    Chan, P.H.5
  • 22
    • 43749093843 scopus 로고    scopus 로고
    • Interleukin-6 induces proliferation in adult spinal cord-derived neural progenitors via the jak2/stat3 pathway with egf-induced mapk phosphorylation
    • Kang MK, Kang SK. Interleukin-6 induces proliferation in adult spinal cord-derived neural progenitors via the JAK2/STAT3 pathway with EGF-induced MAPK phosphorylation. Cell Prolif 2008; 41: 377-92.
    • (2008) Cell Prolif , vol.41 , pp. 377-379
    • Kang, M.K.1    Kang, S.K.2
  • 23
    • 4143071470 scopus 로고    scopus 로고
    • Transplanted human fetal neural stem cells survive, migrate, and differentiate in ischemic rat cerebral cortex
    • Kelly S, Bliss TM, Shah AK, Sun GH, Ma M, Foo WC, et al. Transplanted human fetal neural stem cells survive, migrate, and differentiate in ischemic rat cerebral cortex. Proc Natl Acad Sci USA 2004; 101: 11839-44.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 11839-11834
    • Kelly, S.1    Bliss, T.M.2    Shah, A.K.3    Sun, G.H.4    Ma, M.5    Foo, W.C.6
  • 24
    • 72449142133 scopus 로고    scopus 로고
    • Ck2 is a novel negative regulator of nadph oxidase and a neuroprotectant in mice after cerebral ischemia
    • Kim GS, Jung JE, Niizuma K, Chan PH. CK2 is a novel negative regulator of NADPH oxidase and a neuroprotectant in mice after cerebral ischemia. J Neurosci 2009; 29: 14779-89.
    • (2009) J Neurosci , vol.29 , pp. 14779-14778
    • Kim, G.S.1    Jung, J.E.2    Niizuma, K.3    Chan, P.H.4
  • 25
    • 79952832252 scopus 로고    scopus 로고
    • When are pro-inflammatory cytokines safe in heart failure?
    • Lecour S, James RW. When are pro-inflammatory cytokines SAFE in heart failure? Eur Heart J 2011; 32: 680-5.
    • (2011) Eur Heart J , vol.32 , pp. 680-685
    • Lecour, S.1    James, R.W.2
  • 26
    • 34447274187 scopus 로고    scopus 로고
    • Human neural stem cells over-expressing vegf provide neuroprotection, angiogenesis and functional recovery in mouse stroke model
    • doi:10.1371/journal.pone.0000156
    • Lee HJ, Kim KS, Park IH, Kim SU. Human neural stem cells over-expressing VEGF provide neuroprotection, angiogenesis and functional recovery in mouse stroke model. PLoS One 2007; 2: e156, doi:10.1371/journal.pone.0000156.
    • (2007) PLoS One , vol.2
    • Lee, H.J.1    Kim, K.S.2    Park, I.H.3    Kim, S.U.4
  • 27
    • 74949087489 scopus 로고    scopus 로고
    • Stem cells in human neurodegenerative disorders -Time for clinical translation?
    • Lindvall O, Kokaia Z. Stem cells in human neurodegenerative disorders -Time for clinical translation? J Clin Invest 2010; 120: 29-40.
    • (2010) J Clin Invest , vol.120 , pp. 29-24
    • Lindvall, O.1    Kokaia, Z.2
  • 28
    • 33749455560 scopus 로고    scopus 로고
    • Neuroprotection by pigf gene-modified human mesenchymal stem cells after cerebral ischaemia
    • Liu H, Honmou O, Harada K, Nakamura K, Houkin K, Hamada H, et al. Neuroprotection by PIGF gene-modified human mesenchymal stem cells after cerebral ischaemia. Brain 2006; 129: 2734-45.
    • (2006) Brain , vol.129 , pp. 2734-2734
    • Liu, H.1    Honmou, O.2    Harada, K.3    Nakamura, K.4    Houkin, K.5    Hamada, H.6
  • 29
    • 84984763363 scopus 로고    scopus 로고
    • Mechanisms, challenges and opportunities in stroke
    • Lo EH, Dalkara T, Moskowitz MA. Mechanisms, challenges and opportunities in stroke. Nat Rev Neurosci 2003; 4: 399-415.
    • (2003) Nat Rev Neurosci , vol.4 , pp. 399-394
    • Lo, E.H.1    Dalkara, T.2    Moskowitz, M.A.3
  • 30
    • 33744815599 scopus 로고    scopus 로고
    • Evaluating therapeutic targets for reperfusion-related brain hemorrhage
    • Maier CM, Hsieh L, Crandall T, Narasimhan P, Chan PH. Evaluating therapeutic targets for reperfusion-related brain hemorrhage. Ann Neurol 2006; 59: 929-38.
    • (2006) Ann Neurol , vol.59 , pp. 929-923
    • Maier, C.M.1    Hsieh, L.2    Crandall, T.3    Narasimhan, P.4    Chan, P.H.5
  • 31
    • 33646010041 scopus 로고    scopus 로고
    • Roles for nf-b in nerve cell survival, plasticity, and disease
    • Mattson MP, Meffert MK. Roles for NF-B in nerve cell survival, plasticity, and disease. Cell Death Differ 2006; 13: 852-60.
    • (2006) Cell Death Differ , vol.13 , pp. 852-856
    • Mattson, M.P.1    Meffert, M.K.2
  • 32
    • 0031974368 scopus 로고    scopus 로고
    • Mitochondrial susceptibility to oxidative stress exacerbates cerebral infarction that follows permanent focal cerebral ischemia in mutant mice with manganese superoxide dismutase deficiency
    • Murakami K, Kondo T, Kawase M, Li Y, Sato S, Chen SF, et al. Mitochondrial susceptibility to oxidative stress exacerbates cerebral infarction that follows permanent focal cerebral ischemia in mutant mice with manganese superoxide dismutase deficiency. J Neurosci 1998; 18: 205-13.
    • (1998) J Neurosci , vol.18 , pp. 205-201
    • Murakami, K.1    Kondo, T.2    Kawase, M.3    Li, Y.4    Sato, S.5    Chen, S.F.6
  • 33
    • 70349847390 scopus 로고    scopus 로고
    • Endothelial cells support survival, proliferation, and neuronal differentiation of transplanted adult ischemia-induced neural stem/progenitor cells after cerebral infarction
    • Nakagomi N, Nakagomi T, Kubo S, Nakano-Doi A, Saino O, Takata M, et al. Endothelial cells support survival, proliferation, and neuronal differentiation of transplanted adult ischemia-induced neural stem/progenitor cells after cerebral infarction. Stem Cells 2009; 27: 2185-95.
    • (2009) Stem Cells , vol.27 , pp. 2185-2189
    • Nakagomi, N.1    Nakagomi, T.2    Kubo, S.3    Nakano-Doi, A.4    Saino, O.5    Takata, M.6
  • 35
    • 0035964305 scopus 로고    scopus 로고
    • Activation of signal transducer and activator of transcription 3 protects cardiomyocytes from hypoxia/reoxygenation-induced oxidative stress through the upregulation of manganese superoxide dismutase
    • Negoro S, Kunisada K, Fujio Y, Funamoto M, Darville MI, Eizirik DL, et al. Activation of signal transducer and activator of transcription 3 protects cardiomyocytes from hypoxia/reoxygenation-induced oxidative stress through the upregulation of manganese superoxide dismutase. Circulation 2001; 104: 979-81.
    • (2001) Circulation , vol.104 , pp. 979-978
    • Negoro, S.1    Kunisada, K.2    Fujio, Y.3    Funamoto, M.4    Darville, M.I.5    Eizirik, D.L.6
  • 37
    • 61349130664 scopus 로고    scopus 로고
    • Ambivalent aspects of interleukin-6 in cerebral ischemia: Inflammatory versus neurotrophic aspects
    • Suzuki S, Tanaka K, Suzuki N. Ambivalent aspects of interleukin-6 in cerebral ischemia: inflammatory versus neurotrophic aspects. J Cereb Blood Flow Metab 2009; 29: 464-79.
    • (2009) J Cereb Blood Flow Metab , vol.29 , pp. 464-467
    • Suzuki, S.1    Tanaka, K.2    Suzuki, N.3
  • 38
    • 20844441770 scopus 로고    scopus 로고
    • Stat3 confers resistance against hypoxia/reoxygenation-induced oxidative injury in hepatocytes through upregulation of mn-sod
    • Terui K, Enosawa S, Haga S, Zhang HQ, Kuroda H, Kouchi K, et al. Stat3 confers resistance against hypoxia/reoxygenation-induced oxidative injury in hepatocytes through upregulation of Mn-SOD. J Hepatol 2004; 41: 957-65.
    • (2004) J Hepatol , vol.41 , pp. 957-956
    • Terui, K.1    Enosawa, S.2    Haga, S.3    Zhang, H.Q.4    Kuroda, H.5    Kouchi, K.6
  • 39
    • 59749103836 scopus 로고    scopus 로고
    • Therapeutic benefits of angiogenetic gene-modified human mesenchymal stem cells after cerebral ischemia
    • Toyama K, Honmou O, Harada K, Suzuki J, Houkin K, Hamada H, et al. Therapeutic benefits of angiogenetic gene-modified human mesenchymal stem cells after cerebral ischemia. Exp Neurol 2009; 216: 47-55.
    • (2009) Exp Neurol , vol.216 , pp. 47-45
    • Toyama, K.1    Honmou, O.2    Harada, K.3    Suzuki, J.4    Houkin, K.5    Hamada, H.6
  • 40
    • 67649390844 scopus 로고    scopus 로고
    • Signal transducer and activator of transcription 3-stimulated hypoxia inducible factor-1-mediates estrogen receptor-induced mesenchymal stem cell vascular endothelial growth factor production
    • Wang M, Tan J, Coffey A, Fehrenbacher J, Weil BR, Meldrum DR. Signal transducer and activator of transcription 3-stimulated hypoxia inducible factor-1-mediates estrogen receptor-induced mesenchymal stem cell vascular endothelial growth factor production. J Thorac Cardiovasc Surg 2009; 138: 163-71.
    • (2009) J Thorac Cardiovasc Surg , vol.138 , pp. 163-167
    • Wang, M.1    Tan, J.2    Coffey, A.3    Fehrenbacher, J.4    Weil, B.R.5    Meldrum, D.R.6
  • 42
    • 45549101405 scopus 로고    scopus 로고
    • Control of endothelial cell proliferation and migration by vegf signaling to histone deacetylase 7
    • Wang S, Li X, Parra M, Verdin E, Bassel-Duby R, Olson EN. Control of endothelial cell proliferation and migration by VEGF signaling to histone deacetylase 7. Proc Natl Acad Sci USA 2008; 105: 7738-43.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 7738-7734
    • Wang, S.1    Li, X.2    Parra, M.3    Verdin, E.4    Bassel-Duby, R.5    Olson, E.N.6
  • 43
    • 20244366112 scopus 로고    scopus 로고
    • Transplantation of embryonic stem cells overexpressing bcl-2 promotes functional recovery after transient cerebral ischemia
    • Wei L, Cui L, Snider BJ, Rivkin M, Yu SS, Lee C-S, et al. Transplantation of embryonic stem cells overexpressing Bcl-2 promotes functional recovery after transient cerebral ischemia. Neurobiol Dis 2005; 19: 183-93.
    • (2005) Neurobiol Dis , vol.19 , pp. 183-189
    • Wei, L.1    Cui, L.2    Snider, B.J.3    Rivkin, M.4    Yu, S.S.5    Lee, C.-S.6
  • 44
    • 0033797255 scopus 로고    scopus 로고
    • Vegf enhances angiogenesis and promotes blood-brain barrier leakage in the ischemic brain
    • Zhang ZG, Zhang L, Jiang Q, Zhang R, Davies K, Powers C, et al. VEGF enhances angiogenesis and promotes blood-brain barrier leakage in the ischemic brain. J Clin Invest 2000; 106: 829-38.
    • (2000) J Clin Invest , vol.106 , pp. 829-823
    • Zhang, Z.G.1    Zhang, L.2    Jiang, Q.3    Zhang, R.4    Davies, K.5    Powers, C.6


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