Potential implications of nanoparticle characterization on in vitro and in vivo gene delivery

Therapeutic Delivery

Volumn 3, Issue 11, 2012, Pages 1347-1356

  Nimesh, Surendra ^a  

^a CLIN RESEARCH INSTITUTE OF MONTREAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CHITOSAN; DEXTRAN; DOXORUBICIN; GOLD NANOPARTICLE; HYALURONIC ACID; MACROGOL; N (2 HYDROXYPROPYL)METHACRYLAMIDE COPOLYMER; NANOCAPSULE; NANOPARTICLE; NANOSPHERE; PLASMID DNA; POLYASPARTIC ACID; POLYETHYLENEIMINE; POVIDONE; QUANTUM DOT;

DRUG STABILITY; DRUG STERILITY; GENE DELIVERY SYSTEM; GENE VECTOR; GENETIC TRANSFECTION; HUMAN; IN VITRO GENE TRANSFER; IN VIVO GENE TRANSFER; LIGHT SCATTERING; LIPOSOMAL GENE DELIVERY SYSTEM; NANOMEDICINE; NANOPHARMACEUTICS; NONHUMAN; PARTICLE SIZE; PHYSICAL CHEMISTRY; POLYMERIZATION; PRIORITY JOURNAL; REVIEW; SCANNING ELECTRON MICROSCOPY; SURFACE PROPERTY; TRANSMISSION ELECTRON MICROSCOPY; ZETA POTENTIAL;

EID: 84870201319     PISSN: 20415990     EISSN: 20416008     Source Type: Journal    
DOI: 10.4155/tde.12.110     Document Type: Review

References (64)

1. Loo C, Lowery A, Halas N, West J, Drezek R. Immunotargeted nanoshells for integrated cancer imaging and therapy. Nano Lett. 5(4), 709-711 (2005). (Pubitemid 40609745)
2. Kim YK, Kwak HS, Kim CS, Chung GH, Han YM, Lee JM. Hepatocellular carcinoma in patients with chronic liver disease: comparison of SPIO-enhanced MR imaging and 16-detector row CT. Radiology 238(2), 531-541 (2006). (Pubitemid 43134365)
3. Portney NG, Ozkan M. Nano-oncology: drug delivery, imaging, and sensing. Anal. Bioanal. Chem. 384(3), 620-630 (2006). (Pubitemid 43237915)
4. Ogris M, Wagner E. Targeting tumors with non-viral gene delivery systems. Drug Discov. To d a y 7(8), 479-485 (2002). (Pubitemid 34532575)
5. Lavertu M, Methot S, Tran-Khanh N, Buschmann MD. High effciency gene transfer using chitosan/DNA nanoparticles with specifc combinations of molecular weight and degree of deacetylation. Biomaterials 27(27), 4815-4824 (2006). (Pubitemid 43880352)
6. Jean M, Smaoui F, Lavertu M et al. Chitosan-plasmid nanoparticle formulations for IM and SC delivery of recombinant FGF-2 and PDGF-BB or generation of antibodies. Gene Ther. 16(9), 1097-1110 (2009).
7. Nimesh S, Thibault MM, Lavertu M, Buschmann MD. Enhanced gene delivery mediated by low molecular weight chitosan/DNA complexes: effect of pH and serum. Mol. Biotechnol. 46(2), 182-196 (2010).
8. Dauty E, Remy JS, Blessing T, Behr JP. Dimerizable cationic detergents with a low cmc condense plasmid DNA into nanometric particles and transfect cells in culture. J. Am. Chem. Soc. 123(38), 9227-9234 (2001). (Pubitemid 32900293)
9. Lee H, Williams SK, Allison SD, Anchordoquy TJ. Analysis of self-assembled cationic lipid-DNA gene carrier complexes using fow feld-fow fractionation and light scattering. Anal. Chem. 73(4), 837-843 (2001). (Pubitemid 32174466)
10. Sakurai F, Inoue R, Nishino Y et al. Effect of DNA/liposome mixing ratio on the physicochemical characteristics, cellular uptake and intracellular traffcking of plasmid DNA/cationic liposome complexes and subsequent gene expression. J. Control. Release 66(2-3), 255-269 (2000). (Pubitemid 30160862)
11. Zauner W, Farrow NA, Haines AM. In vitro uptake of polystyrene microspheres: effect of particle size, cell line and cell density. J. Control. Release 7 1(1), 39-51 (2001). (Pubitemid 32195440)
12. Desai MP, Labhasetwar V, Walter E, Levy RJ, Amidon GL. The mechanism of uptake of biodegradable microparticles in Caco-2 cells is size dependent. Pharm. Res. 14(11), 1568-1573 (1997). (Pubitemid 28009208)
13. Prabha S, Zhou WZ, Panyam J, Labhasetwar V. Size-dependency of nanoparticle-mediated gene transfection: studies with fractionated nanoparticles. Int. J. Pharm. 244(1-2), 105-115 (2002).
14. Xu DM, Yao SD, Liu YB et al. Size-dependent properties of M-PEIs nanogels for gene delivery in cancer cells. Int. J. Pharm. 338(1-2), 291-296 (2007).
15. Chithrani BD, Ghazani AA, Chan WC. Determining the size and shape dependence of gold nanoparticle uptake into mammalian cells. Nano. Lett. 6(4), 662-668 (2006).
16. Ahmed M, Deng Z, Narain R. Study of transfection effciencies of cationic glyconanoparticles of different sizes in human cell line. ACS Appl. Mater. Interfaces 1(9), 1980-1987 (2009).
17. Cebrián V, Martín-Saavedra F, Yagüe C, Arruebo M, Santamaría J, Vilaboa N. Size-dependent transfection effciency of PEI-coated gold nanoparticles. Acta Biomater. 7(10), 3645-3655 (2011).
18. Aoyama Y, Kanamori T, Nakai T et al. Artifcial viruses and their application to gene delivery. Size-controlled gene coating with glycocluster nanoparticles. J. Am. Chem. Soc. 125(12), 3455-3457 (2003). (Pubitemid 36512419)
19. Nakai T, Kanamori T, Sando S, Aoyama Y Remarkably size-regulated cell invasion by artifcial viruses. Saccharide-dependent self-aggregation of glycoviruses and its consequences in glycoviral gene delivery. J. Am. Chem. Soc. 125(28), 8465-8475 (2003). (Pubitemid 36858414)
20. Gao H, Shi W, Freund LB. Mechanics of receptor-mediated endocytosis. Proc. Natl Acad. Sci. USA 102(27), 9469-9474 (2005). (Pubitemid 40981705)
21. Mao HQ, Roy K, Troung-Le VL et al. Chitosan/DNA nanoparticles as gene carriers: synthesis, characterization and transfection effciency. J. Control. Release 70(3), 399-421 (2001). (Pubitemid 32155463)
22. Luo D, Saltzman WM. Synthetic DNA delivery systems. Nat. Biotech. 18(1), 33-37 (2000). (Pubitemid 30041168)
23. Nimesh S, Chandra R. Guanidinium-grafted polyethylenimine: An effcient transfecting agent for mammalian cells. Eur. J. Pharm. Biopharm. 68(3), 647-655 (2008). (Pubitemid 351318220)
24. Xiang SD, Scholzen A, Minigo G et al. Pathogen recognition and development of particulate vaccines: does size matter? Methods 40(1), 1-9 (2006). (Pubitemid 44415493)
25. Schipper NG, Olsson S, Hoogstraate JA, Deboer AG, Varum KM, Artursson P. Chitosans as absorption enhancers for poorly absorbable drugs 2: mechanism of absorption enhancement. Pharm. Res. 14(7), 923-929 (1997). (Pubitemid 27326989)
26. Ma Z, Lim LY. Uptake of chitosan and associated insulin in Caco-2 cell monolayers: A comparison between chitosan molecules and chitosan nanoparticles. Pharm. Res. 20(11), 1812-1819 (2003). (Pubitemid 37449455)
27. Hess GT, Humphries WH, Fay NC, Payne CK. Cellular binding, motion, and internalization of synthetic gene delivery polymers. Biochim. Biophys. Acta 1773(10), 1583-1588 (2007). (Pubitemid 47498613)
28. Wiethoff CM, Koe JG, Koe GS, Middaugh CR. Compositional effects of cationic lipid/DNA delivery systems on transgene expression in cell culture. J. Pharm. Sci. 93(1), 108-123 (2004). (Pubitemid 38081819)
29. He C, Hu Y, Yin L, Tang C, Yin C. Effects of particle size and surface charge on cellular uptake and biodistribution of polymeric nanoparticles. Biomaterials 31(13), 3657-3666 (2010).
30. Xiao K, Li Y, Luo J et al. The effect of surface charge on in vivo biodistribution of PEG-oligocholic acid based micellar nanoparticles. Biomaterials 32(13), 3435-3446 (2011).
31. Harush-Frenkel O, Rozentur E, Benita S, Altschuler Y. Surface charge of nanoparticles determines their endocytic and transcytotic pathway in polarized MDCK cells. Biomacromolecules 9(2), 435-443 (2008). (Pubitemid 351298461)
32. Harush-Frenkel O, Debotton N, Benita S, Altschuler Y Targeting of nanoparticles to the clathrin-mediated endocytic pathway Biochem. Biophys. Res. Commun. 353(1), 26-32 (2007). (Pubitemid 44958337)
33. Rejman J, Bragonzi A, Conese M. Role of clathrin-and caveolae-mediated endocytosis in gene transfer mediated by lipo-and polyplexes. Mol. Ther. 12(3), 468-474 (2005). (Pubitemid 41150132)
34. Sahay G, Kim JO, Kabanov AV, Bronich TK. The exploitation of differential endocytic pathways in normal and tumor cells in the selective targeting of nanoparticulate chemotherapeutic agents. Biomaterials 31(5), 923-933 (2010).
35. Zhang LW, Monteiro-Riviere NA. Mechanisms of quantum dot nanoparticle cellular uptake. Toxicol. Sci. 110(1), 138-155 (2009).
36. Khan JA, Pillai B, Das TK, Singh Y, Maiti S. Molecular effects of uptake of gold nanoparticles in HeLa cells. ChemBioChem. 8(11), 1237-1240 (2007). (Pubitemid 47171988)
37. Jung SH, Kim SK, Jung SH et al. Increased stability in plasma and enhanced cellular uptake of thermally denatured albumin-coated liposomes. Colloids and Surfaces B: Biointerfaces 76(2), 434-440 (2010).
38. Xie J, Xu C, Kohler N, Hou Y, Sun S. Controlled PEGylation of monodisperse FeO nanoparticles for reduced non-specifc 34 uptake by macrophage cells. Adv. Mater. 19(20), 3163-3166 (2007). (Pubitemid 350044454)
39. Chang E, Yu WW, Colvin VL, Drezek R. Quantifying the infuence of surface coatings on quantum dot uptake in cells. J. Biomed. Nanotechnol. 1(4), 397-401 (2005).
40. Champion JA, Katare YK, Mitragotri S. Making polymeric micro-and nanoparticles of complex shapes. Proc. Natl Acad. Sci. USA 104(29), 11901-11904 (2007). (Pubitemid 47185602)
41. Champion JA, Mitragotri S. Role of target geometry in phagocytosis. Proc. Natl Acad. Sci. USA 103(13), 4930-4934 (2006).
42. Alexander L, Dhaliwal K, Simpson J, Bradley M. Dunking doughnuts into cells-selective cellular translocation and in vivo ana lysis of polymeric micro-doughnuts. Chem. Commun. (Camb.) (30), 3507-3509 (2008).
43. Decuzzi P, Ferrari M. The receptor-mediated endocytosis of nonspherical particles. Biophys. J. 94(10), 3790-3797 (2008).
44. Liu G, Li D, Pasumarthy MK et al. Nanoparticles of compacted DNA transfect postmitotic cells. J. Biol. Chem. 278(35), 32578-32586 (2003). (Pubitemid 37055695)
45. Prabhakaran K, Kumbhar CS, Raghunath S, Gokhale NM, Sharma SC. Effect of concentration of ammonium poly (acry la te) dispersant and MgO on coagulation characteristics of aqueous alumina direct coagulation casting slurries. J. Am. Ceram. Soc. 91(6), 1933-1938 (2008).
46. Sato K, Kondo S, Tsukada M, Ishigaki T, Kamiya H. Infuence of solid fraction on the optimum molecular weight of polymer dispersants in aqueous TiO2 nanoparticle suspensions. J. Am. Ceram. Soc. 90(11), 3401-3406 (2007). (Pubitemid 350075809)
47. Laarz E, Meurk A, Yanez JA, Bergström L. Silicon nitride colloidal probe measurements: interparticle forces and the role of surface-segment interactions in poly(acrylic acid) adsorption from aqueous solution. J. Am. Ceram. Soc. 84(8), 1675-1682 (2001). (Pubitemid 33670292)
48. Manchanda R, Nimesh S. Controlled size chitosan nanoparticles as an effcient, biocompatible oligonucleotides delivery system. J. Appl. Polym. Sci. 118(4), 2071-2077 (2010).
49. Romoren K, Aaberge A, Smistad G, Thu BJ, Evensen O. Long-term stability of chitosan-based polyplexes. Pharm. Res. 21(12), 2340-2346 (2004). (Pubitemid 40568449)
50. Werth S, Urban-Klein B, Dai L et al. A low molecular weight fraction of polyethylenimine (PEI) displays increased transfection effciency of DNA and siRNA in fresh or lyophilized complexes. J. Control. Release 112(2), 257-270 (2006).
51. Brus C, Kleemann E, Aigner A, Czubayko F, Kissel T. Stabilization of oligonucleotide-polyethylen imine complexes by freeze-drying: physicochemical and biological characterization. J. Control. Release 95(1), 119-131 (2004). (Pubitemid 38167686)
52. Allison SD, Molina MC, Anchordoquy TJ. Stabilization of lipid/DNA complexes during the freezing step of the lyophilization process: the particle isolation hypothesis. Biochim. Biophys. Acta 1468(1-2), 127-138 (2000).
53. Andersen MO, Howard KA, Paludan SR, Besenbacher F, Kjems J. Delivery of siRNA from lyophilized polymeric surfaces. Biomaterials 29(4), 506-512 (2008). (Pubitemid 350103802)
54. Athanasiou KA, Niederauer GG, Agrawal CM. Sterilization, toxicity, biocompatibility and clinical applications of polylactic acid/polyglycolic acid copolymers. Biomaterials 17(2), 93-102 (1996). (Pubitemid 26031365)
55. Memisoglu-Bilensoy E, Hincal AA. Sterile, injectable cyclodextrin nanoparticles: effects of gamma irradiation and autoclaving. Int. J. Pharm. 311(1-2), 203-208 (2006).
56. Volland C, Wolff M, Kissel T. The infuence of terminal gamma-sterilization on captopril containing poly(d, l-lactide-co-glycolide) microspheres. J. Control. Release 31(3), 293-305 (1994). (Pubitemid 124012504)
57. Goldbach P, Brochart H, Wehrlé P, Stamm A. Sterile fltration of liposomes: retention of encapsulated carboxyfuorescein. Int. J. Pharm. 117(2), 225-230 (1995).
58. Konan YN, Gurny R, Allémann E. Preparation and characterization of sterile and freeze-dried sub-200 nm nanoparticles. Int. J. Pharm. 233(1-2), 239-252 (2002).
59. Maksimenko O, Pavlov E, Toushov E et al. Radiation sterilisation of doxorubicin bound to poly(butyl cyanoacrylate) nanoparticles. Int. J. Pharm. 356(1-2), 325-332 (2008).
60. Brigger I, Armand-Lefevre L, Chaminade P et al. The stenlying effect of high hydrostatic pressure on thermally and hydrolytically labile nanosized carriers. Pharm. Res. 20(4), 674-683 (2003). (Pubitemid 36438914)
61. Tsukada Y, Hara K, Bando Y et al. Particle size control of poly(d, l-lactide-co-glycolide) nanospheres for sterile applications. Int. J. Pharm. 370(1-2), 196-201 (2009).
62. Wörle G, Siekmann B, Koch MHJ, Bunjes H. Transformation of vesicular into cubic nanoparticles by autoclaving of aqueous monoolein/poloxamer dispersions. Eur. J. Pharm. Sci. 27(1), 44-53 (2006). (Pubitemid 41728254)
63. Cavalli R, Caputo O, Carlotti ME, Trotta M, Scarnecchia C, Gasco MR. Sterilization and freeze-drying of drug-free and drug-loaded solid lipid nanoparticles. Int. J. Pharm. 148(1), 47-54 (1997). (Pubitemid 27152216)
64. Sanna V, Kirschvink N, Gustin P et al. Preparation and in vivo toxicity study of solid lipid microparticles as carrier for pulmonary administration. AAPS PharmSciTech 5(2), e27 (2004).