Treatment with heme arginate alleviates adipose tissue inflammation and improves insulin sensitivity and glucose metabolism in a rat model of Human primary aldosteronism

Free Radical Biology and Medicine

Volumn 53, Issue 12, 2012, Pages 2277-2286

  Jadhav, Ashok ^a   Ndisang, Joseph Fomusi ^a  

^a UNIVERSITY OF SASKATCHEWAN   (Canada)

Author keywords

Adiponectin; DOCA salt hypertension; Endothelin 1; Free radicals; Heme oxygenase; Insulin sensitivity; Visceral adiposity

Indexed keywords

8 ISOPROSTANE; GLUCOSE; HEME ARGINATE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INSULIN; INTERCELLULAR ADHESION MOLECULE 1; MONOCYTE CHEMOTACTIC PROTEIN 1; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR AP 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG EFFICACY; DRUG MECHANISM; GLUCOSE METABOLISM; INFLAMMATION; INSULIN RESISTANCE; INSULIN SENSITIVITY; MALE; NONHUMAN; OBESITY; PRIMARY HYPERALDOSTERONISM; PRIORITY JOURNAL; RAT; TREATMENT OUTCOME;

ADIPONECTIN; DOCA SALT HYPERTENSION; ENDOTHELIN-1; FREE RADICALS; HEME OXYGENASE; INSULIN SENSITIVITY; VISCERAL ADIPOSITY;

ADIPOSITY; ANIMALS; ARGININE; CHEMOKINE CCL2; DISEASE MODELS, ANIMAL; ENDOTHELIN-1; ENZYME ACTIVATORS; GENE EXPRESSION; GLUCOSE; HEME; HEME OXYGENASE (DECYCLIZING); HUMANS; HYPERALDOSTERONISM; INSULIN; INSULIN RESISTANCE; INTERCELLULAR ADHESION MOLECULE-1; INTRA-ABDOMINAL FAT; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MALE; MESOPORPHYRINS; NF-KAPPA B; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTOR AP-1;

RATTUS;

EID: 84870180860     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2012.10.529     Document Type: Article

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