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Volumn 151, Issue 2, 2010, Pages 549-560

Up-regulating the heme oxygenase system with hemin improves insulin sensitivity and glucose metabolism in adult spontaneously hypertensive rats

Author keywords

[No Author keywords available]

Indexed keywords

8 ISOPROSTANE; ADIPONECTIN; BILIRUBIN; CATALASE; CYCLIC AMP; CYCLIC GMP; FERRITIN; GLUCOSE; GLUCOSE TRANSPORTER 4; HEME; HEME OXYGENASE; HEME OXYGENASE 1; HEMIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INSULIN; MESOPORPHYRIN; STRESS ACTIVATED PROTEIN KINASE; SUPEROXIDE DISMUTASE;

EID: 74949102157     PISSN: 00137227     EISSN: 00137227     Source Type: Journal    
DOI: 10.1210/en.2009-0471     Document Type: Article
Times cited : (83)

References (65)
  • 1
    • 57749186455 scopus 로고    scopus 로고
    • Prevalence of insulin resistance and related risk factors for cardiovascular disease in patients with essential hypertension
    • Lima NK, Abbasi F, Lamendola C, Reaven G M 2009 Prevalence of insulin resistance and related risk factors for cardiovascular disease in patients with essential hypertension. Am J Hypertens 22:106-111
    • (2009) Am J Hypertens , vol.22 , pp. 106-111
    • Lima, N.K.1    Abbasi, F.2    Lamendola, C.3    Reaven, G.M.4
  • 4
    • 33645860825 scopus 로고    scopus 로고
    • Reactive oxygen species have a causal role in multiple forms of insulin resistance
    • Houstis N, Rosen ED, Lander ES 2006 Reactive oxygen species have a causal role in multiple forms of insulin resistance. Nature 440: 944-948
    • (2006) Nature , vol.440 , pp. 944-948
    • Houstis, N.1    Rosen, E.D.2    Lander, E.S.3
  • 5
    • 0036796875 scopus 로고    scopus 로고
    • Oxidative stress and stress-activated signaling pathways: A unifying hypothesis of type 2 diabetes
    • Evans JL, Goldfine ID, Maddux BA, Grodsky GM 2002 Oxidative stress and stress-activated signaling pathways: a unifying hypothesis of type 2 diabetes. Endocr Rev 23:599-622
    • (2002) Endocr Rev , vol.23 , pp. 599-622
    • Evans, J.L.1    Goldfine, I.D.2    Maddux, B.A.3    Grodsky, G.M.4
  • 6
    • 0037219409 scopus 로고    scopus 로고
    • Are oxidative stress-activated signaling pathways mediators of insulin resistance and β-cell dysfunction?
    • Evans JL, Goldfine ID, Maddux BA, Grodsky GM 2003 Are oxidative stress-activated signaling pathways mediators of insulin resistance and β-cell dysfunction? Diabetes 52:1-8
    • (2003) Diabetes , vol.52 , pp. 1-8
    • Evans, J.L.1    Goldfine, I.D.2    Maddux, B.A.3    Grodsky, G.M.4
  • 7
    • 43849104298 scopus 로고    scopus 로고
    • Antioxidants preserve redox balance and inhibit c-Jun-N-terminal kinase pathway while improving insulin signaling in fat-fed rats: Evidence for the role of oxidative stress on IRS-1 serine phosphorylation and insulin resistance
    • Vinayagamoorthi R, Bobby Z, SridharMG 2008 Antioxidants preserve redox balance and inhibit c-Jun-N-terminal kinase pathway while improving insulin signaling in fat-fed rats: evidence for the role of oxidative stress on IRS-1 serine phosphorylation and insulin resistance. J Endocrinol 197:287-296
    • (2008) J Endocrinol , vol.197 , pp. 287-296
    • Vinayagamoorthi, R.1    Bobby, Z.2    SridharMG3
  • 8
    • 41149150716 scopus 로고    scopus 로고
    • ADPHoxidases, reactive oxygen species, and hypertension: Clinical implications and therapeutic possibilities
    • Paravicini TM, TouyzRM2008NADPHoxidases, reactive oxygen species, and hypertension: clinical implications and therapeutic possibilities. Diabetes Care 31(Suppl 2):S170-S180
    • (2008) Diabetes Care , vol.31 , Issue.SUPPL. 2
    • Paravicini, T.M.1    TouyzRM2
  • 9
    • 0042822096 scopus 로고    scopus 로고
    • Intramuscular heat shock protein 72 and heme oxygenase-1 mRNA are reduced in patients with type 2 diabetes: Evidence that insulin resistance is associated with a disturbed antioxidant defense mechanism
    • Bruce CR, Carey AL, Hawley JA, Febbraio MA 2003 Intramuscular heat shock protein 72 and heme oxygenase-1 mRNA are reduced in patients with type 2 diabetes: evidence that insulin resistance is associated with a disturbed antioxidant defense mechanism. Diabetes 52: 2338-2345
    • (2003) Diabetes , vol.52 , pp. 2338-2345
    • Bruce, C.R.1    Carey, A.L.2    Hawley, J.A.3    Febbraio, M.A.4
  • 11
    • 41149177025 scopus 로고    scopus 로고
    • Pharmacological and clinical aspects of heme oxygenase
    • Abraham NG, Kappas A 2008 Pharmacological and clinical aspects of heme oxygenase. Pharmacol Rev 60:79-127
    • (2008) Pharmacol Rev , vol.60 , pp. 79-127
    • Abraham, N.G.1    Kappas, A.2
  • 12
    • 55949136575 scopus 로고    scopus 로고
    • Interaction among heme oxygenase, nuclear factor-κB, and transcription activating factors in cardiac hypertrophy in hypertension
    • Jadhav A, Torlakovic E, Ndisang JF 2008 Interaction among heme oxygenase, nuclear factor-κB, and transcription activating factors in cardiac hypertrophy in hypertension. Hypertension 52:910-917
    • (2008) Hypertension , vol.52 , pp. 910-917
    • Jadhav, A.1    Torlakovic, E.2    Ndisang, J.F.3
  • 13
    • 43949106899 scopus 로고    scopus 로고
    • Crosstalk between the heme oxygenase system, aldosterone, and phospholipase C in hypertension
    • Ndisang JF, Lane N, Jadhav A 2008 Crosstalk between the heme oxygenase system, aldosterone, and phospholipase C in hypertension. J Hypertens 26:1188-1199
    • (2008) J Hypertens , vol.26 , pp. 1188-1199
    • Ndisang, J.F.1    Lane, N.2    Jadhav, A.3
  • 14
    • 33644845569 scopus 로고    scopus 로고
    • Role of oxidative stress, endoplasmic reticulum stress, and c-Jun N-terminal kinase in pancreatic β-cell dysfunction and insulin resistance
    • Kaneto H, Nakatani Y, Kawamori D, Miyatsuka T, Matsuoka TA, Matsuhisa M, Yamasaki Y 2006 Role of oxidative stress, endoplasmic reticulum stress, and c-Jun N-terminal kinase in pancreatic β-cell dysfunction and insulin resistance. Int J Biochem Cell Biol 38:782-793
    • (2006) Int J Biochem Cell Biol , vol.38 , pp. 782-793
    • Kaneto, H.1    Nakatani, Y.2    Kawamori, D.3    Miyatsuka, T.4    Matsuoka, T.A.5    Matsuhisa, M.6    Yamasaki, Y.7
  • 16
    • 0030839740 scopus 로고    scopus 로고
    • Role of blood flow in the regulation of muscle glucose uptake
    • Baron AD, Clark MG 1997 Role of blood flow in the regulation of muscle glucose uptake. Annu Rev Nutr 17:487-499
    • (1997) Annu Rev Nutr , vol.17 , pp. 487-499
    • Baron, A.D.1    Clark, M.G.2
  • 17
    • 0029037495 scopus 로고
    • The chemistry of peroxynitrite: A product from the reaction of nitric oxide with superoxide
    • Pryor WA, Squadrito GL 1995 The chemistry of peroxynitrite: a product from the reaction of nitric oxide with superoxide. Am J Physiol 268:L699-L722
    • (1995) Am J Physiol , vol.268
    • Pryor, W.A.1    Squadrito, G.L.2
  • 18
    • 41149155892 scopus 로고    scopus 로고
    • Treatment of obese diabetic mice with a heme oxygenase inducer reduces visceral and subcutaneous adiposity, increases adiponectin levels, and improves insulin sensitivity and glucose tolerance
    • Li M, Kim DH, Tsenovoy PL, Peterson SJ, Rezzani R, Rodella LF, Aronow WS, Ikehara S, Abraham NG 2008 Treatment of obese diabetic mice with a heme oxygenase inducer reduces visceral and subcutaneous adiposity, increases adiponectin levels, and improves insulin sensitivity and glucose tolerance. Diabetes 57:1526-1535
    • (2008) Diabetes , vol.57 , pp. 1526-1535
    • Li, M.1    Kim, D.H.2    Tsenovoy, P.L.3    Peterson, S.J.4    Rezzani, R.5    Rodella, L.F.6    Aronow, W.S.7    Ikehara, S.8    Abraham, N.G.9
  • 19
    • 14244268391 scopus 로고    scopus 로고
    • Defective glucose-stimulated insulin release in the diabetic Goto-Kakizaki (GK) rat coincides with reduced activity of the islet carbon monoxide signaling pathway
    • Mosén H, Salehi A, Alm P, Henningsson R, Jimenez-Feltström J, Ostenson CG, Efendic S, Lundquist I 2005 Defective glucose-stimulated insulin release in the diabetic Goto-Kakizaki (GK) rat coincides with reduced activity of the islet carbon monoxide signaling pathway. Endocrinology 146:1553-1558
    • (2005) Endocrinology , vol.146 , pp. 1553-1558
    • Mosén, H.1    Salehi, A.2    Alm, P.3    Henningsson, R.4    Jimenez-Feltström, J.5    Ostenson, C.G.6    Efendic, S.7    Lundquist, I.8
  • 20
    • 23744511665 scopus 로고    scopus 로고
    • Potenza MA, Marasciulo FL, Chieppa DM, Brigiani GS, Formoso G, Quon MJ, Montagnani M 2005 Insulin resistance in spontaneously hypertensive rats is associated with endothelial dysfunction characterized by imbalance betweenNOand ET-1 production.AmJ Physiol Heart Circ Physiol 289:H813-H822
    • Potenza MA, Marasciulo FL, Chieppa DM, Brigiani GS, Formoso G, Quon MJ, Montagnani M 2005 Insulin resistance in spontaneously hypertensive rats is associated with endothelial dysfunction characterized by imbalance betweenNOand ET-1 production.AmJ Physiol Heart Circ Physiol 289:H813-H822
  • 23
    • 66649132533 scopus 로고    scopus 로고
    • Up-regulating the hemeoxygenase system enhances insulin sensitivity and improves glucose metabolism in insulin-resistant diabetes in Goto-Kakizaki rats
    • Ndisang JF, Jadhav A 2009 Up-regulating the hemeoxygenase system enhances insulin sensitivity and improves glucose metabolism in insulin-resistant diabetes in Goto-Kakizaki rats. Endocrinology 150:2627-2636
    • (2009) Endocrinology , vol.150 , pp. 2627-2636
    • Ndisang, J.F.1    Jadhav, A.2
  • 24
    • 66049154851 scopus 로고    scopus 로고
    • Hemin therapy attenuates kidney injury in deoxycorticosterone acetate-salt hypertensive rats
    • Jadhav A, Torlakovic E, Ndisang JF 2009 Hemin therapy attenuates kidney injury in deoxycorticosterone acetate-salt hypertensive rats. Am J Physiol Renal Physiol 296:F521-F534
    • (2009) Am J Physiol Renal Physiol , vol.296
    • Jadhav, A.1    Torlakovic, E.2    Ndisang, J.F.3
  • 25
    • 66449100734 scopus 로고    scopus 로고
    • The heme oxygenase system abates hyperglycemia in Zucker diabetic fatty rats by potentiating insulin-sensitizing pathways
    • Ndisang JF, Lane N, Jadhav A 2009 The heme oxygenase system abates hyperglycemia in Zucker diabetic fatty rats by potentiating insulin-sensitizing pathways. Endocrinology 150:2098-2108
    • (2009) Endocrinology , vol.150 , pp. 2098-2108
    • Ndisang, J.F.1    Lane, N.2    Jadhav, A.3
  • 26
    • 65649110522 scopus 로고    scopus 로고
    • Heme oxygenase system enhances insulin sensitivity and glucose metabolism in streptozotocin-induced diabetes
    • Ndisang JF, Jadhav A 2009 Heme oxygenase system enhances insulin sensitivity and glucose metabolism in streptozotocin-induced diabetes. Am J Physiol Endocrinol Metab 296:E829-E841
    • (2009) Am J Physiol Endocrinol Metab , vol.296
    • Ndisang, J.F.1    Jadhav, A.2
  • 27
    • 66149135526 scopus 로고    scopus 로고
    • Upregulation of the heme oxygenase system ameliorates postprandial and fasting hyperglycemia in type 2 diabetes
    • Ndisang JF, Lane N, Jadhav A 2009 Upregulation of the heme oxygenase system ameliorates postprandial and fasting hyperglycemia in type 2 diabetes. Am J Physiol Endocrinol Metab 296: E1029-E1041
    • (2009) Am J Physiol Endocrinol Metab , vol.296
    • Ndisang, J.F.1    Lane, N.2    Jadhav, A.3
  • 34
    • 0025332748 scopus 로고
    • Effect of heme arginate administration on blood pressure in spontaneously hypertensive rats
    • Levere RD, Martasek P, Escalante B, Schwartzman ML, Abraham NG 1990 Effect of heme arginate administration on blood pressure in spontaneously hypertensive rats. J Clin Invest 86:213-219
    • (1990) J Clin Invest , vol.86 , pp. 213-219
    • Levere, R.D.1    Martasek, P.2    Escalante, B.3    Schwartzman, M.L.4    Abraham, N.G.5
  • 35
    • 42149134209 scopus 로고    scopus 로고
    • Reduced levels of cyclic AMPcontribute to the enhanced oxidative stress in vascular smooth muscle cells from spontaneously hypertensive rats
    • Saha S, Li Y, Anand-Srivastava MB 2008 Reduced levels of cyclic AMPcontribute to the enhanced oxidative stress in vascular smooth muscle cells from spontaneously hypertensive rats. Can J Physiol Pharmacol 86:190-198
    • (2008) Can J Physiol Pharmacol , vol.86 , pp. 190-198
    • Saha, S.1    Li, Y.2    Anand-Srivastava, M.B.3
  • 36
    • 33746270279 scopus 로고    scopus 로고
    • Increased oxidative stress is associated with decreased circulating levels of adiponectin in Japanese metabolically obese, normal-weight men with normal glucose tolerance
    • Katsuki A, Suematsu M, Gabazza EC, Murashima S, Nakatani K, Togashi K, Yano Y, Adachi Y, Sumida Y 2006 Increased oxidative stress is associated with decreased circulating levels of adiponectin in Japanese metabolically obese, normal-weight men with normal glucose tolerance. Diabetes Res Clin Pract 73:310-314
    • (2006) Diabetes Res Clin Pract , vol.73 , pp. 310-314
    • Katsuki, A.1    Suematsu, M.2    Gabazza, E.C.3    Murashima, S.4    Nakatani, K.5    Togashi, K.6    Yano, Y.7    Adachi, Y.8    Sumida, Y.9
  • 37
    • 12944299790 scopus 로고    scopus 로고
    • A protective effect of adiponectin against oxidative stress in Japanese Americans: The association between adiponectin or leptin and urinary isoprostane
    • Nakanishi S, Yamane K, Kamei N, Nojima H, Okubo M, Kohno N 2005 A protective effect of adiponectin against oxidative stress in Japanese Americans: the association between adiponectin or leptin and urinary isoprostane. Metabolism 54:194-199
    • (2005) Metabolism , vol.54 , pp. 194-199
    • Nakanishi, S.1    Yamane, K.2    Kamei, N.3    Nojima, H.4    Okubo, M.5    Kohno, N.6
  • 40
    • 33749861323 scopus 로고    scopus 로고
    • Nitric oxide inhibits, and carbon monoxide activates, islet acid α-glucoside hydrolase activities in parallel with glucose-stimulated insulin secretion
    • Mosén H, Salehi A, Henningsson R, Lundquist I 2006 Nitric oxide inhibits, and carbon monoxide activates, islet acid α-glucoside hydrolase activities in parallel with glucose-stimulated insulin secretion. J Endocrinol 190:681-693
    • (2006) J Endocrinol , vol.190 , pp. 681-693
    • Mosén, H.1    Salehi, A.2    Henningsson, R.3    Lundquist, I.4
  • 45
    • 0035282334 scopus 로고    scopus 로고
    • Mammalian MAP kinase signalling cascades
    • Chang L, Karin M 2001 Mammalian MAP kinase signalling cascades. Nature 410:37-40
    • (2001) Nature , vol.410 , pp. 37-40
    • Chang, L.1    Karin, M.2
  • 46
    • 39049142758 scopus 로고    scopus 로고
    • Secretion of atherogenic risk factor apolipoprotein B-100 is increased by a potential mechanism of JNK/PKC-mediated insulin resistance in liver cells
    • Jin UH,Kang YJ, Chang YC, Kim CH2008 Secretion of atherogenic risk factor apolipoprotein B-100 is increased by a potential mechanism of JNK/PKC-mediated insulin resistance in liver cells. J Cell Biochem 103:908-919
    • (2008) J Cell Biochem , vol.103 , pp. 908-919
    • Jin, U.H.1    Kang, Y.J.2    Chang, Y.C.3    Kim, C.H.4
  • 47
    • 0032961802 scopus 로고    scopus 로고
    • Heme oxygenase and carbon monoxide: Regulatory roles in islet hormone re-lease: a biochemical, immunohistochemical, and confocal microscopic study
    • Henningsson R, Alm P, Ekström P, Lundquist I 1999 Heme oxygenase and carbon monoxide: regulatory roles in islet hormone re-lease: a biochemical, immunohistochemical, and confocal microscopic study. Diabetes 48:66-76
    • (1999) Diabetes , vol.48 , pp. 66-76
    • Henningsson, R.1    Alm, P.2    Ekström, P.3    Lundquist, I.4
  • 49
    • 0027407240 scopus 로고
    • Selection of metalloporphyrin heme oxygenase inhibitors based on potency and photoreactivity
    • Vreman HJ, Ekstrand BC, Stevenson DK 1993 Selection of metalloporphyrin heme oxygenase inhibitors based on potency and photoreactivity. Pediatr Res 33:195-200
    • (1993) Pediatr Res , vol.33 , pp. 195-200
    • Vreman, H.J.1    Ekstrand, B.C.2    Stevenson, D.K.3
  • 53
    • 51449087136 scopus 로고    scopus 로고
    • L-4F treatment reduces adiposity, increases adiponectin levels, and improves insulin sensitivity in obese mice
    • Peterson SJ, Drummond G, Kim DH, Li M, Kruger AL, Ikehara S, Abraham NG2008 L-4F treatment reduces adiposity, increases adiponectin levels, and improves insulin sensitivity in obese mice. J Lipid Res 49:1658-1669
    • (2008) J Lipid Res , vol.49 , pp. 1658-1669
    • Peterson, S.J.1    Drummond, G.2    Kim, D.H.3    Li, M.4    Kruger, A.L.5    Ikehara, S.6    Abraham, N.G.7
  • 58
    • 44649123524 scopus 로고    scopus 로고
    • Effects of different levels of exercise volume on endothelium-dependent vasodilation: Roles of nitric oxide synthase and heme oxygenase
    • Sun MW, Zhong MF, Gu J, Qian FL, Gu JZ, Chen H 2008 Effects of different levels of exercise volume on endothelium-dependent vasodilation: roles of nitric oxide synthase and heme oxygenase. Hypertens Res 31:805-816
    • (2008) Hypertens Res , vol.31 , pp. 805-816
    • Sun, M.W.1    Zhong, M.F.2    Gu, J.3    Qian, F.L.4    Gu, J.Z.5    Chen, H.6
  • 59
    • 33845516684 scopus 로고    scopus 로고
    • Treatment of spontaneously hypertensive rats with rosiglitazone and/or enalapril restores balance between vasodilator and vasoconstrictor actions of insulin with simultaneous improvement in hypertension and insulin resistance
    • Potenza MA, Marasciulo FL, Tarquinio M, Quon MJ, Montagnani M 2006 Treatment of spontaneously hypertensive rats with rosiglitazone and/or enalapril restores balance between vasodilator and vasoconstrictor actions of insulin with simultaneous improvement in hypertension and insulin resistance. Diabetes 55:3594 - 3603
    • (2006) Diabetes , vol.55 , pp. 3594-3603
    • Potenza, M.A.1    Marasciulo, F.L.2    Tarquinio, M.3    Quon, M.J.4    Montagnani, M.5
  • 61
    • 0028307310 scopus 로고
    • Identification of binding sites for transcription factors NF-κB and AP-2 in the promoter region of the human heme oxygenase 1 gene
    • Lavrovsky Y, Schwartzman ML, Levere RD, Kappas A, Abraham NG 1994 Identification of binding sites for transcription factors NF-κB and AP-2 in the promoter region of the human heme oxygenase 1 gene. Proc Natl Acad Sci USA 91:5987-5991
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 5987-5991
    • Lavrovsky, Y.1    Schwartzman, M.L.2    Levere, R.D.3    Kappas, A.4    Abraham, N.G.5
  • 62
    • 51349085477 scopus 로고    scopus 로고
    • Reduction of hepatic glucocorticoid receptor and hexose-6-phosphate dehydrogenase expression ameliorates diet-induced obesity and insulin resistance in mice
    • Liu Y, Nakagawa Y, Wang Y, Liu L, Du H, Wang W, Ren X, Lutfy K, Friedman TC 2008 Reduction of hepatic glucocorticoid receptor and hexose-6-phosphate dehydrogenase expression ameliorates diet-induced obesity and insulin resistance in mice. J Mol Endocrinol 41:53-64
    • (2008) J Mol Endocrinol , vol.41 , pp. 53-64
    • Liu, Y.1    Nakagawa, Y.2    Wang, Y.3    Liu, L.4    Du, H.5    Wang, W.6    Ren, X.7    Lutfy, K.8    Friedman, T.C.9
  • 63
    • 0141483051 scopus 로고    scopus 로고
    • Haeme-oxygenase 1 expression in rat pancreatic βcells is stimulated by supraphysiological glucose concentrations and by cyclic AMP
    • Jonas JC, Guiot Y, Rahier J, Henquin JC 2003 Haeme-oxygenase 1 expression in rat pancreatic βcells is stimulated by supraphysiological glucose concentrations and by cyclic AMP. Diabetologia 46: 1234-1244
    • (2003) Diabetologia , vol.46 , pp. 1234-1244
    • Jonas, J.C.1    Guiot, Y.2    Rahier, J.3    Henquin, J.C.4
  • 64
    • 61549122310 scopus 로고    scopus 로고
    • Pleiotropic functions of biliverdin reductase: Cellular signaling and generation of cytoprotective and cytotoxic bilirubin
    • Kapitulnik J, Maines MD 2009 Pleiotropic functions of biliverdin reductase: cellular signaling and generation of cytoprotective and cytotoxic bilirubin. Trends Pharmacol Sci 30:129-137
    • (2009) Trends Pharmacol Sci , vol.30 , pp. 129-137
    • Kapitulnik, J.1    Maines, M.D.2
  • 65
    • 35349023691 scopus 로고    scopus 로고
    • Heme-oxygenase-1-induced protection against hypoxia/ reoxygenation is dependent on biliverdin reductase and its interaction with PI3K/Akt pathway
    • Pachori AS, Smith A, McDonald P, Zhang L, Dzau VJ, Melo LG 2007 Heme-oxygenase-1-induced protection against hypoxia/ reoxygenation is dependent on biliverdin reductase and its interaction with PI3K/Akt pathway. J Mol Cell Cardiol 43:580-592
    • (2007) J Mol Cell Cardiol , vol.43 , pp. 580-592
    • Pachori, A.S.1    Smith, A.2    McDonald, P.3    Zhang, L.4    Dzau, V.J.5    Melo, L.G.6


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