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Volumn 59, Issue , 2013, Pages 39-47

Synthesis, antiproliferative activity and tubulin targeting effect of acridinone and dioxophenothiazine derivatives

(12) Verones, Valérie a Flouquet, Nathalie a Lecoeur, Marie a Lemoine, Amelie b Farce, Amaury a Baldeyrou, Brigitte a Mahieu, Christine a Wattez, Nicole a Lansiaux, Amélie a Goossens, Jean François a Berthelot, Pascal a Lebegue, Nicolas a

a UNIV LILLE (France)

b Faculté des Sciences Pharmaceutiques et Biologiques Université de Lille (France)

Author keywords

Acridinone; Cytotoxicity; Phenothiazine; Tubulin polymerization

Indexed keywords

10H 1 [2 (3 HYDROXY 4 METHOXYPHENYL)ETHYL]PHENOTHIAZINE 5,5 DIOXIDE; 10H 1 [2 (3,4 DIHYDROXYPHENYL)ETHYL]PHENOTHIAZINE 5,5 DIOXIDE; 10H 1 [2 (3,4 DIMETHOXYPHENYL)ETHYL]PHENOTHIAZINE 5,5 DIOXIDE; 10H 1 [2 (3,4,5 TRIMETHOXYPHENYL)ETHYL]PHENOTHIAZINE 5,5 DIOXIDE; 10H 1 [2 (4 METHOXYPHENYL)ETHYL]PHENOTHIAZINE 5,5 DIOXIDE; 10H 4 [2 (3 HYDROXY 4 METHOXYPHENYL)ETHYL]ACRIDIN 9 ONE; 10H 4 [2 (3,4 DIHYDROXYPHENYL)ETHYL]ACRIDIN 9 ONE; 10H 4 [2 (3,4 DIMETHOXYPHENYL)ETHYL]ACRIDIN 9 ONE; 10H 4 [2 (3,4,5 TRIMETHOXYPHENYL)ETHYL]ACRIDIN 9 ONE; 10H 4 [2 (4 METHOXYPHENYL)ETHYL]ACRIDIN 9 ONE; ACRIDONE DERIVATIVE; ANTINEOPLASTIC AGENT; DNA TOPOISOMERASE; DNA TOPOISOMERASE (ATP HYDROLYSING); PHENOTHIAZINE DERIVATIVE; TUBULIN; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; CARCINOMA CELL; CELL CYCLE; CELL CYCLE PROGRESSION; CELL STRAIN HT29; COLON ADENOCARCINOMA; CONTROLLED STUDY; CYTOTOXICITY; DRUG MECHANISM; DRUG SYNTHESIS; DRUG TARGETING; ENZYME INHIBITION; G2 PHASE CELL CYCLE CHECKPOINT; HEAD AND NECK SQUAMOUS CELL CARCINOMA; HUMAN; HUMAN CELL; HYDROGEN BOND; IC 50; IN VITRO STUDY; LEUKEMIA CELL; MEMBRANE PERMEABILITY; MICROTUBULE ASSEMBLY; MOLECULAR MODEL; PHARMACOPHORE; PROTEIN STRUCTURE;

ACRIDONES; ANTINEOPLASTIC AGENTS; CELL PROLIFERATION; DRUG DELIVERY SYSTEMS; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; MOLECULAR STRUCTURE; PHENOTHIAZINES; STRUCTURE-ACTIVITY RELATIONSHIP; TUBULIN; TUMOR CELLS, CULTURED;

EID: 84870169901 PISSN: 02235234 EISSN: 17683254 Source Type: Journal
DOI: 10.1016/j.ejmech.2012.10.051 Document Type: Article

Times cited : (22)

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