Alginate/CaCO3 hybrid nanoparticles for efficient codelivery of antitumor gene and drug

Molecular Pharmaceutics

Volumn 9, Issue 10, 2012, Pages 2887-2893

  Zhao, Dong ^a   Liu, Chuan Jun ^a   Zhuo, Ren Xi ^a   Cheng, Si Xue ^a  

^a WUHAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ALGINIC ACID; DOXORUBICIN; NANOPARTICLE; PROTEIN P53; ANTINEOPLASTIC AGENT; CALCIUM CARBONATE; DNA; DOXORUBICIN DNA; DOXORUBICIN-DNA; DRUG CARRIER; GLUCURONIC ACID; HEXURONIC ACID;

APOPTOSIS; ARTICLE; CELL MEMBRANE; CELL POPULATION; CELL STRUCTURE; CHEMICAL MODIFICATION; CHROMATIN IMMUNOPRECIPITATION; COMPETITIVE INHIBITION; CONFORMATION; CONTROLLED STUDY; CYTOPLASM; DIFFUSION; DRUG DELIVERY SYSTEM; DRUG RELEASE; FEMALE; GENETIC TRANSFECTION; HELA CELL; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; NANOENCAPSULATION; NONVIRAL GENE DELIVERY SYSTEM; PARTICLE SIZE; PRIORITY JOURNAL; PROTEIN EXPRESSION; ULTRAVIOLET SPECTROPHOTOMETRY; ZETA POTENTIAL; CHEMISTRY; DNA ADDUCT; DRUG EFFECT; GENE TRANSFER; GENETICS; METHODOLOGY; PLASMID; TUMOR CELL LINE;

ALGINATES; ANTINEOPLASTIC AGENTS; APOPTOSIS; CALCIUM CARBONATE; CELL LINE, TUMOR; DNA; DNA ADDUCTS; DOXORUBICIN; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; GENE TRANSFER TECHNIQUES; GLUCURONIC ACID; HELA CELLS; HEXURONIC ACIDS; HUMANS; NANOPARTICLES; PLASMIDS;

EID: 84870159045     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp3002123     Document Type: Article

References (31)

1. Edelstein, M. L.; Abedi, M. R.; Wixon, J. Gene therapy clinical trials worldwide to 2007 - an update J. Gene Med. 2007, 9, 833-842
2. Li, R.; Hehlman, R.; Sachs, R.; Duesberg, P. Chromosomal alterations cause the high rates and wide ranges of drug resistance in cancer cells Cancer Genet. Cytogenet. 2003, 163, 44-56
3. Duesberg, P.; Li, R.; Sachs, R.; Fabarius, A.; Upender, M.; Hehlmann, R. Cancer drug resistance: the central role of the karyotype Drug Resist. Updates 2003, 10, 51-58
4. Wiradharma, N.; Tong, Y. W.; Yang, Y. Y. Self-assembled oligopeptide nanostructures for co-delivery of drug and gene with synergistic therapeutic effect Biomaterials 2009, 30, 3100-3109
5. Koivusalo, R.; Krausz, E.; Helenius, H.; Hietanen, S. Chemotherapy compounds in cervical cancer cells primed by reconstitution of p53 function after short interfering RNA mediated degradation of human Papilloma virus 18 E6 mRNA: opposite effect of siRNA in combination with different drugs Mol. Pharmacol. 2005, 68, 372-382
6. Gjerzet, R. A.; Mercola, D. Sensitization of tumors to chemotherapy through gene therapy Adv. Exp. Med. Biol. 2000, 465, 273-291
7. Lu, X.; Wang, Q. Q.; Xu, F. J.; Tang, G. P.; Yang, W. T. A cationic prodrug/therapeutic gene nanocomplex for the synergistic treatment of tumors Biomaterials 2011, 32, 4849-4856
8. Ventura, A.; Kirsch, D. G.; McLaughlin, M. E.; Tuveson, D. A.; Grimm, J.; Lintault, L.; Newman, J.; Reczek, E. E.; Weissleder, R.; Jacks, T. Restoration of p53 function leads to tumour regression in vivo Nature 2007, 445, 661-665
9. Olivier, M.; Goldgar, D. E.; Sodha, N.; Ohgaki, H.; Kleihues, P.; Hainaut, P.; Eeles, R. A. Li-Fraumeni and related syndromes correlation between tumor type, family structure, and TP53 genotype Cancer Res. 2003, 63, 6643-6650
10. Zhan, M.; Yu, D.; Lang, A.; Li, L.; Pollock, R. E. Wild type p53 sensitizes soft tissue sarcoma cells to doxorubicin by down-regulating multidrug resistance-1 expression Cancer 2001, 92, 1556-1566
11. Oshima, K.; Naoi, Y.; Kishi, K.; Nakamura, Y.; Iwamoto, T.; Shimazu, K.; Nakayama, T.; Kim, S. J.; Baba, Y.; Tamaki, Y.; Noguchi, S. Gene expression signature of TP53 but not its mutation status predicts response to sequential paclitaxel and 5-FU/epirubicin/cyclophosphamide in human breast cancer Cancer Lett. 2011, 307, 149-157
12. Lee, S.; Baek, M.; Kim, H. Y.; Ha, J. H.; Jeoung, D. I. Mechanism of doxorubicin-induced cell death and expression profile analysis Biotechnol. Lett. 2002, 24, 1147-1151
13. Ahmed, F.; Pakunlu, R. I.; Brannan, A.; Bates, F.; Minko, T.; Discher, D. E. Biodegradable polymersomes loaded with both paclitaxel and doxorubicin permeate and shrink tumors, inducing apoptosis in proportion to accumulated drug J. Controlled Release 2006, 116, 150-158
14. Chen, S.; Cheng, S. X.; Zhuo, R. X. Self-assembly strategy for preparation of polymer-based nanoparticles for drug and gene delivery Macromol. Biosci. 2011, 11, 576-589
15. Zhu, C.; Jung, S.; Luo, S.; Meng, F.; Zhu, X.; Park, T.; Zhong, Z. Y. Co-delivery of siRNA and paclitaxel into cancer cells by biodegradable cationic micelles based on PDMAEMA-PCL-PDMAEMA triblock copolymers Biomaterials 2010, 31, 2408-2416
16. Beh, C. W.; Seow, W. Y.; Wang, Y.; Zhang, Y.; Ong, Z. Y.; Ee, P. L. R.; Yang, Y. Y. Efficient delivery of Bcl-2-targeted siRNA using cationic polymer nanoparticles: downregulating mRNA expression level and sensitizing cancer cells to anticancer drug Biomacromolecules 2009, 10, 41-48
17. Xu, Z.; Zhang, Z.; Chen, Y.; Chen, L.; Lin, L.; Li, Y. The characteristics and performance of a multifunctional nanoassembly system for the co-delivery of docetaxel and iSur-pDNA in a mouse hepatocellular carcinoma model Biomaterials 2010, 31, 916-922
18. Saad, M.; Garbuzenko, O. B.; Minko, T. Co-delivery of siRNA and an anticancer drug for treatment of multidrug-resistant cancer Nanomedicine 2008, 3, 761-776
19. Meng, H.; Liong, M.; Xia, T.; Li, Z.; Ji, Z.; Zink, J. I.; Nel, A. E. Engineered design of mesoporous silica nanoparticles to deliver doxorubicin and P-glycoprotein siRNA to overcome drug resistance in a cancer cell line ACS Nano 2010, 4, 4539-4550
20. Chen, A. M.; Zhang, M.; Wei, D.; Stueber, D.; Taratula, O.; Minko, T.; He, H. Co-delivery of doxorubicin and Bcl-2 siRNA by mesoporous silica nanoparticles enhances the efficacy of chemotherapy in multidrug-resistant cancer cells Small 2009, 5, 2673-2677
21. Olton, D.; Li, J.; Wilson, M. E.; Rogers, T.; Close, J.; Huang, L.; Kumta, P. N.; Sfeir, C. Nanostructured calcium phosphates (NanoCaPs) for non-viral gene delivery: Influence of the synthesis parameters on transfection efficiency Biomaterials 2007, 28, 1267-1279
22. Hanifi, A.; Fathi, M. H.; Mir Mohammad Sadeghi, H. Effect of strontium ions substitution on gene delivery related properties of calcium phosphate nanoparticles J. Mater. Sci. Mater. Med. 2010, 21, 2601-2609
23. Sun, B.; Tran, K. K.; Shen, H. Enabling customization of non-viral gene delivery systems for individual cell types by surface-induced mineralization Biomaterials 2009, 30, 6386-6393
24. Cheang, T. Y.; Wang, S. M.; Hu, Z. J.; Xing, Z. H.; Chang, G. Q.; Yao, C.; Liu, Y.; Zhang, H.; Xu, A. W. Calcium carbonate/CaIP6 nanocomposite particles as gene delivery vehicles for human vascular smooth muscle cells J. Mater. Chem. 2010, 20, 8050-8055
25. Chen, S.; Zhao, D.; Li, F.; Zhuo, R. X.; Cheng, S. X. Co-delivery of gene and drug with nanostructured calcium carbonate for cancer therapy RSC Adv. 2012, 2, 1820-1826
26. Chen, S.; Li, F.; Zhuo, R. X.; Cheng, S. X. Efficient non-viral gene delivery mediated by nanostructured calcium carbonate in solution-based transfection and solid-phase transfection Mol. BioSyst. 2011, 7, 2841-2847
27. Zhao, D.; Zhuo, R. X.; Cheng, S. X. Alginate modified nanostructured calcium carbonate with enhanced delivery efficiency for gene and drug delivery Mol. BioSyst. 2012, 8, 753-759
28. 3 microparticles Colloids Surf., A 2010, 353, 132-139
29. Wang, J.; Chen, S.; Zong, J. Y.; Zhao, D.; Li, F.; Zhuo, R. X.; Cheng, S. X. Calcium carbonate/carboxymethyl chitosan hybrid microspheres and nanospheres for drug delivery J. Phys. Chem. C 2010, 114, 18940-18945
30. Lee, Y.; Park, S. Y.; Mok, H.; Park, T. G. Synthesis, characterization, antitumor activity of pluronic mimicking copolymer micelles conjugated with doxorubicin via acid-cleavable linkage Bioconjugate Chem. 2008, 19, 525-531
31. Momparler, R. L.; Karon, M.; Siegel, S. E.; Avila, F. Effect of adriamycin on DNA, RNA, and protein synthesis in cell-free systems and intact cells Cancer Res. 1976, 36, 2891-2895