Preparation, characterization, and cytotoxicity of CPT/Fe2O3-embedded PLGA ultrafine composite fibers: A synergistic approach to develop promising anticancer material

International Journal of Nanomedicine

Volumn 7, Issue , 2012, Pages 1659-1670

  Amna, Touseef ^a   Shamshi Hassan, M ^a   Nam, Ki Taek ^a   Bing, Yang You ^b   Barakat, Nasser A M ^a   Khil, Myung Seob ^a   Kim, Hak Yong ^a  

^a Chonbuk National University   (South Korea)

^b HENAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

C2C12 cells; Camptothecin; Cytotoxicity; Electrospinning; Fe2O3 nanoparticles

Indexed keywords

CAMPTOTHECIN; FERRIC OXIDE; NANOCOMPOSITE; POLYGLACTIN;

ANIMAL CELL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL VIABILITY; COMPOSITE MATERIAL; CONCENTRATION RESPONSE; CONTROLLED STUDY; CRYSTALLIZATION; DRUG CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG EFFECT; DRUG STABILITY; ELECTRON PROBE MICROANALYSIS; ELECTROSPINNING; IN VITRO STUDY; MOUSE; NANOENCAPSULATION; NANOPHARMACEUTICS; NONHUMAN; PHYSICAL CHEMISTRY; ROENTGEN SPECTROSCOPY; SCANNING ELECTRON MICROSCOPY; SLOW DRUG RELEASE; THERMOGRAVIMETRY; TIMED DRUG RELEASE; TRANSMISSION ELECTRON MICROSCOPY; ULTRAVIOLET SPECTROSCOPY; X RAY DIFFRACTION;

ANIMALS; CAMPTOTHECIN; CELL LINE; CELL SURVIVAL; DRUG CARRIERS; DRUG SYNERGISM; ELECTROCHEMICAL TECHNIQUES; LACTIC ACID; MAGNETITE NANOPARTICLES; MICE; NANOFIBERS; NANOTECHNOLOGY; POLYGLYCOLIC ACID;

EID: 84870016193     PISSN: 11769114     EISSN: 11782013     Source Type: Journal    
DOI: 10.2147/IJN.S24467     Document Type: Article

References (37)

1. Redinbo MR, Stewart L, Kuhn P, Champoux JJ, Hol WG. Crystal structures of human topoisomerase I in covalent and noncovalent complexes with DNA. Science. 1998;279(5356):1504-1513.
2. Staker BL, Hjerrild K, Feese MD, Behnke CA, Burgin AB Jr, Stewart L. The mechanism of topoisomerase I poisoning by a camptothecin analogue. Proc Natl Acad Sci U S A. 2002;99(24): 15387-15392.
3. Li SY, Adair KT. Camptotheca acuminata Decaisne (Xi Shu, Chinese Happy Tree): A Promising Antitumor and Antiviral Tree for the 21st Century. Nacogdoches, TX: Stephen F Austin State University;1994.
4. Oberlies NH, Kroll DJ. Camptothecin and taxol: historic achievements in natural products research. J Nat Prod. 2004;67(2):129-135.
5. Wall ME, Wani MC, Cook CE, Palmer KH, McPhail AT, Sim GA. Plant antitumor agents. I. The isolation and structure of camptothecin, a novel alkaloidal leukemia and tumor inhibitor from Camptotheca acuminata. J Am Chem Soc. 1966;88(16):3888-3890.
6. Fassberg J, Stella VJ. A kinetic and mechanistic study of the hydrolysis of camptothecin and some analogues. J Pharm Sci. 1992;81(7):676-684.
7. Chourpa I, Millot JM, Sockalingum GD, Riou JF, Manfait M. Kinetics of lactone hydrolysis in antitumor drugs of camptothecin series as studied by fluorescence spectroscopy. Biochim Biophys Acta. 1998;1379(3):353-366.
8. Venditto VJ, Simanek EE. Cancer therapies utilizing the camptothecin: a review of in vivo literature. Mol Pharm. 2010;7(2):307-349.
9. 4 and polylactide nanofibers for application in drug uptake and induction of cell death of leukemia cancer cells. Langmuir. 2008;24(5):2151-2156.
10. Lalloo A, Chao P, Hu P, Stein S, Sinko PJ. Pharmacokinetic and pharmacodynamic evaluation of a novel in situ forming poly(ethylene glycol)-based hydrogel for the controlled delivery of the camptothecins. J Control Release. 2006;112(3):333-342.
11. Zhang L, Yang M, Wang Q, et al. 10-Hydroxycamptothecin loaded nanoparticles: preparation and antitumor activity in mice. J Control Release. 2007;119(2):153-162.
12. Zahedi P, Rezaeian I, Ranaei-Siadat SO, Jafari SH, Supaphol PA. A review on wound dressings with an emphasis on electrospun nanofibrous polymeric bandages. Polym Adv Technol. 2010;21(2):77-95.
13. Reneker DH, Chun I. Nanometer diameter fibers of polymer produced by electrospinning. Nanotechnology. 1996;7:216-223.
14. Huang ZM, Zhang YZ, Kotaki M, Ramakrishna S. A review on polymer nanofibers by electrospinning and their applications in nanocomposites. Compos Sci Technol. 2003;63(15):2223-2253.
15. Greiner A, Wendorff JH. Electrospinning: a fascinating method for the preparation of ultrathin fibers. Angew Chem Int Ed Engl. 2007;46(30):5670-5703.
16. Matsumura Y, Maeda H. A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs. Cancer Res. 1986; 46(12 Pt 1):6387-6392.
17. Duncan R. The dawning era of polymer therapeutics. Nat Rev Drug Discov. 2003;2(5):347-360.
18. Jain TK, Morales MA, Sahoo SK, Leslie-Pelecky DL, Labhasetwar V. Iron oxide nanoparticles for sustained delivery of anticancer agents. Mol Pharm. 2005;2(3):194-205.
19. Lubbe AS, Alexiou C, Bergemann C. Clinical applications of magnetic drug targeting. J Surg Res. 2008;95:200-206.
20. Martina MS, Wilhem C, Lesieur S. The effect of magnetic targeting on the uptake of magnetic-fluid-loaded liposomes by human prostatic adenocarcinoma cells. Biomaterials. 2008;29(30):4137-4145.
21. Scarberry KE, Dickerson EB, McDonald JF, Zhang ZJ. Magnetic nanoparticle-peptide conjugates for in vitro and in vivo targeting and extraction of cancer cells. J Am Chem Soc. 2008;130(31):10258-10262.
22. Leuner C, Dressman J. Improving drug solubility for oral delivery using solid dispersion. Eur J Pharm Biopharm. 2000;50(1):47-60.
23. 4 nanoparticles for camptothecin loading and release. Acta Biomater. 2009;5(5):1489-1498.
24. Zhao H, Lee C, Sai P, et al. 20-O-acylcamptothecin derivatives: evidence for lactone stabilization. J Org Chem. 2000;65(15):4601-4606.
25. Lee J, Cho EC, Cho K. Incorporation and release behavior of hydrophobic drug in functionalized poly(D, L-lactide)-block-poly(ethylene oxide) micelles. J Control Release. 2004;94(2-3):323-335.
26. Allen C, Maysinger D, Eisenberg A. Nano-engineering block copolymer aggregates for drug delivery. Colloids Surf B Biointerfaces. 1999;16(1-4):3-27.
27. Liu F, Guo R, Shen M, Wang S, Shi X. Effect of processing variables on the morphology of electrospun poly(lactic acid)-co-(glycolic acid) nanofibers. Macromol Mater Eng. 2009;294(10):666-672.
28. Armentano I, Dottori M, Puglia D, Kenny JM. Effects of carbon nanotubes (CNTs) on the processing and in-vitro degradation of poly(DL-lactide-co-glycolide)/CNT films. J Mater Sci Mater Med. 2008;19(6):2377-2387.
29. Hatefi A, Amsden B. Camptothecin delivery methods. Pharm Res. 2002;19(10):1389-1399.
30. Shenderova A, Burke TG, Schwendeman SP. Stabilization of 10-hydroxycamptothecin in poly(lactide-co-glycolide) microsphere delivery vehicles. Pharm Res. 1997;14(10):1406-1414.
31. Cortesi R, Esposito E, Maietti A, Menegatti E, Nastruzzi C. Formulation study for the antitumor drug camptothecin: liposomes, micellar solutions and a microemulsion. Int J Pharm. 1997;159(1):95-103.
32. Kunii R, Onishi H, Machida Y. Preparation and antitumor characteristics of PLA/(PEG-PPG-PEG) nanoparticles loaded with camptothecin. Eur J Pharm Biopharm. 2007;67(1):9-17.
33. Davis ME. Design and development of IT-101, a cyclodextrin containing polymer conjugate of camptothecin. Adv Drug Deliv Rev. 2009;61(13):1189-1192.
34. Huang ZR, Hua SC, Yang YL, Fang JY. Development and evaluation of lipid nanoparticles for camptothecin delivery: a comparison of solid lipid nanoparticles, nanostructured lipid carriers, and lipid emulsion. Acta Pharmacol Sin. 2008;29(9):1094-1102.
35. Berrada M, Serreqi A, Dabbarh F, Owusu A, Gupta A, Lehnert S. A novel non-toxic camptothecin formulation for cancer chemotherapy. Biomaterials. 2005;26(14):2115-2120.
36. Verreck G, Chun I, Rosenblatt J, et al. Incorporation of drugs in an amorphous state into electrospun nanofibers composed of a water-insoluble, nonbiodegradable polymer. J Control Release. 2003;92(3):349-360.
37. Fernandez-Pacheco R, Marquina C, Valdivia JG, et al. Magnetic nanoparticles for local drug delivery using magnetic implants. J Magn Magn Mater. 2007;311(1):318-322.