Incorporation of drugs in an amorphous state into electrospun nanofibers composed of a water-insoluble, nonbiodegradable polymer

Journal of Controlled Release

Volumn 92, Issue 3, 2003, Pages 349-360

  Verreck, Geert ^a   Chun, Iksoo ^b   Rosenblatt, Joel ^b   Peeters, Jef ^a   Van Dijck, Alex ^a   Mensch, Jurgen ^a   Noppe, Marc ^a   Brewster, Marcus E ^a  

^a JANSSEN RESEARCH AND DEVELOPMENT   (Belgium)

^b JOHNSON AND JOHNSON   (United States)

Author keywords

Electrostatic spinning; Itraconazole; Ketanserin; Nanofibers; Polyurethane

Indexed keywords

DIFFUSION; NANOSTRUCTURED MATERIALS; NONWOVEN FABRICS; POLYURETHANES; SPINNING (FIBERS);

DRUG DIFFUSION; DRUG LOADING;

CONTROLLED DRUG DELIVERY;

ITRACONAZOLE; KETANSERIN; N,N DIMETHYLACETAMIDE; N,N DIMETHYLFORMAMIDE; POLYMER; POLYURETHAN;

ARTICLE; CORRELATION ANALYSIS; DRUG DELIVERY SYSTEM; DRUG DIFFUSION; DRUG RELEASE; LINEAR SYSTEM; LOADING TEST; MEDICAL INSTRUMENTATION; PRIORITY JOURNAL; TIME;

CALORIMETRY, DIFFERENTIAL SCANNING; DELAYED-ACTION PREPARATIONS; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; ELECTROSTATICS; ITRACONAZOLE; KETANSERIN; KINETICS; MICROSCOPY, ELECTRON, SCANNING; MOLECULAR STRUCTURE; NANOTECHNOLOGY; PHASE TRANSITION; POLYMERS; POLYURETHANES;

EID: 1642271597     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-3659(03)00342-0     Document Type: Article

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