Anti-diabetic effect of sorghum extract on hepatic gluconeogenesis of streptozotocin-induced diabetic rats

Nutrition and Metabolism

Volumn 9, Issue , 2012, Pages

  Kim, Jungmin ^a   Park, Yongsoon ^a  

^a Hanyang University   (South Korea)

Author keywords

Diabetic rats; Hepatic gluconeogenetic enzyme expression; Sorghum

Indexed keywords

ANTIDIABETIC AGENT; GLIBENCLAMIDE; GLUCOSE; GLUCOSE TRANSPORTER 4; INSULIN; MITOGEN ACTIVATED PROTEIN KINASE P38; PHOSPHOENOLPYRUVATE CARBOXYKINASE (GTP); PLANT EXTRACT; PROTEIN KINASE B; SORGHUM EXTRACT; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; VERY LOW DENSITY LIPOPROTEIN CHOLESTEROL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CONTROLLED STUDY; DIABETES MELLITUS; DRUG MECHANISM; FOOD INTAKE; GLUCONEOGENESIS; GLUCOSE BLOOD LEVEL; GLUCOSE TOLERANCE TEST; GLUCOSE TRANSPORT; INSULIN BLOOD LEVEL; LIVER FUNCTION; MALE; NONHUMAN; ORGAN WEIGHT; PROTEIN EXPRESSION; RAT; SORGHUM; STREPTOZOCIN DIABETES;

RATTUS; RATTUS NORVEGICUS;

EID: 84869882396     PISSN: None     EISSN: 17437075     Source Type: Journal    
DOI: 10.1186/1743-7075-9-106     Document Type: Article

References (30)

1. Definition, epidemiology and classification of diabetes in children and adolescents. Craig ME, Hattersley A, Donaghue KC, Pediatr Diabetes 2009 10 3 12 19930220
2. New hepatic targets for glycaemic control in diabetes. Agius L, Best Pract Res Clin Endocrinol Metab 2007 21 587 605 10.1016/j.beem.2007.09.001 18054737 (Pubitemid 350177566)
3. Skeletal muscle insulin resistance in obesity-associated type 2 diabetes in monkeys is linked to a defect in insulin activation of protein kinase C-zeta/lambda/iota. Standaert ML, Ortmeyer HK, Sajan MP, Kanoh Y, Bandyopadhyay G, Hansen BC, Farese RV, Diabetes 2002 51 2936 2943 10.2337/diabetes.51.10.2936 12351430
4. p38 Mitogen-activated protein kinase plays a stimulatory role in hepatic gluconeogenesis. Cao W, Collins QF, Becker TC, Robidoux J, Lupo EG Jr, Lupo EG, Xiong Y, Daniel KW, Floering L, Collins S, J Biol Chem 2005 280 42731 42737 10.1074/jbc.M506223200 16272151 (Pubitemid 43049233)
5. Molecular physiology of the regulation of hepatic gluconeogenesis and glycolysis. Pilkis SJ, Granner DK, Annu Rev Physiol 1992 54 885 909 10.1146/annurev.ph.54.030192.004321 1562196
6. How many signals impinge on GLUT4 activation by insulin? He A, Liu X, Liu L, Chang Y, Fang F, Cell Signal 2007 19 1 7 10.1016/j.cellsig.2006.05.018 16919913 (Pubitemid 44880239)
7. Berberine improves glucose metabolism in diabetic rats by inhibition of hepatic gluconeogenesis. Xia X, Yan J, Shen Y, Tang K, Yin J, Zhang Y, Yang D, Liang H, Ye J, Weng J, PLoS One 2011 6 16556 e16565 10.1371/journal.pone.0016556 21304897
8. Chitosan reduces gluconeogenesis and increases glucose uptake in skeletal muscle in streptozotocin-induced diabetic rats. Liu SH, Chang YH, Chiang MT, J Agric Food Chem 2010 58 5795 5800 10.1021/jf100662r 20397731
9. Astragalus polysaccharide improves insulin sensitivity in KKAy mice: regulation of PKB/GLUT4 signaling in skeletal muscle. Liu M, Wu K, Mao X, Wu Y, Ouyang J, J Ethnopharmacol 2010 127 32 37 10.1016/j.jep.2009.09.055 19800959
10. Sorghum phytochemicals and their potential impact on human health. Awika JM, Rooney LW, Phytochemistry 2004 65 1199 1221 10.1016/j.phytochem.2004.04.001 15184005 (Pubitemid 38746667)
11. Anti-oxidative activities of sorghum, foxtail millet and proso millet extracts. Kim JS, Hyun TK, Kim MJ, Afr J Biotechnol 2010 9 2683 2690
12. Antioxidant effect of a crude phenolic extract from sorghum bran in sunflower oil in the presence of ferric ions. Sikwese FE, Duodu KG, Food Chem 2007 104 324 331 10.1016/j.foodchem.2006.11.042 (Pubitemid 46561130)
13. Epidemiologic and dietary evidence for a specific nutritional predisposition to esophageal cancer. van Rensburg SJ, J Natl Cancer Inst 1981 67 243 251 6943364 (Pubitemid 11010355)
14. Sorghum distillers dried grain lipid extract increases cholesterol excretion and decreases plasma and liver cholesterol concentration in hamsters. Hoi JT, Weller CL, Schlegel VL, Cuppett SL, Lee JY, Carr TP, J Funct Foods 2009 1 381 386 10.1016/j.jff.2009.09.005
15. Grain sorghum lipid extract reduces cholesterol absorption and plasma non-HDL cholesterol concentration in hamsters. Carr TP, Weller CL, Schlegel VL, Cuppett SL, Guderian DM Jr, Johnson KR, J Nutr 2005 135 2236 2240 16140904 (Pubitemid 41298393)
16. Antidiabetic effects of three Korean sorghum phenolic extracts in normal and streptozotocin-induced diabetic rats. Chung IM, Kim EH, Yeo MA, Kim SJ, Seo MC, Moon HI, Food Res Int 2011 44 127 132 10.1016/j.foodres.2010.10.051
17. Effect of oral oleoyl-estrone on adipose tissue composition in male rats. Remesar X, Fernández-López JA, Blay MT, Savall P, Salas A, Díaz-Silva M, Esteve M, Grasa MM, Alemany M, Int J Obes Relat Metab Disord 2002 26 1092 102 10.1038/sj.ijo.0802056 12119575
18. Sorghum extract exerts an anti-diabetic effect through improvement of insulin sensitivity via PPAR-γ in mice with high-fat diet. Park JH, Lee SH, Chung IM, Park Y, Nutr Res Pract 2012 6 322 327 10.4162/nrp.2012.6.4.322 22977686
19. The inhibitory effects of ethanol extracts from sorghum, foxtail millet and proso millet on glucosidase and amylase activities. Kim JS, Hyun TK, Kim MJ, Food Chem 2011 124 1647 1651 10.1016/j.foodchem.2010.08.020
20. Hypoglycemic effect of selected sorghum recipes. Lakshmi KB, Vimala V, Nutr Res 1996 16 1651 1658 10.1016/0271-5317(96)00184-4 (Pubitemid 26336953)
21. Establishment and characterization of a novel method for evaluating gluconeogenesis using hepatic cell lines, H4IIE and HepG2. Okamoto T, Kanemoto N, Ban T, Sudo T, Nagano K, Niki I, Arch Biochem Biophys 2009 491 46 52 10.1016/j.abb.2009.09.015 19799852
22. CCAAT/enhancer-binding protein alpha mediates induction of hepatic phosphoenolpyruvate carboxykinase by p38 mitogen-activated protein kinase. Qiao L, MacDougald OA, Shao J, J Biol Chem 2006 281 24390 24397 10.1074/jbc. M603038200 16807249 (Pubitemid 44274211)
23. Activating transcription factor-2 regulates phosphoenolpyruvate carboxykinase transcription through a stress-inducible mitogen-activated protein kinase pathway. Cheong J, Coligan JE, Shuman JD, J Biol Chem 1998 273 22714 22718 10.1074/jbc.273.35.22714 9712902 (Pubitemid 28399843)
24. Inhibition of gluconeogenesis through transcriptional activation of EGR1 and DUSP4 by AMP-activated kinase. Berasi SP, Huard C, Li D, Shih HH, Zhong W, Paulsen JE, Brown EL, Gimeno RE, Martinez RV, J Biol Chem 2006 281 27167 27177 10.1074/jbc.M602416200 16849326 (Pubitemid 44401746)
25. Liver adenosine monophosphate-activated kinase-alpha2 catalytic subunit is a key target for the control of hepatic glucose production by adiponectin and leptin but not insulin. Andreelli F, Foretz M, Knauf C, Cani PD, Perrin C, Iqlesias MA, Pillot B, Bado A, Tronche F, Mithieux G, Vaulont S, Burcelin R, Viollet B, Endocrinology 2006 147 2432 2441 10.1210/en.2005-0898 16455782
26. Berberine stimulates glucose transport through a mechanism distinct from insulin. Zhou L, Yang Y, Wang X, Liu S, Shang W, Yuan G, Li F, Tang J, Chen M, Chen J, Metabolism 2007 56 405 412 10.1016/j.metabol.2006.10.025 17292731 (Pubitemid 46209231)
27. Glucose transporter 4: cycling, compartments and controversies. Dugani CB, Klip A, EMBO Rep 2005 6 1137 1142 10.1038/sj.embor.7400584 16319959 (Pubitemid 41741696)
28. Akt activation is required at a late stage of insulin-induced GLUT4 translocation to the plasma membrane. van Dam EM, Govers R, James DE, Mol Endocrinol 2005 19 1067 1077 10.1210/me.2004-0413 15650020 (Pubitemid 40397069)
29. Insights into insulin resistance and type 2 diabetes from knockout mouse models. Kadowaki T, J Clin Invest 2000 106 459 465 10.1172/JCI10830 10953020 (Pubitemid 30666378)
30. Expression of GLUT1 and GLUT4 glucose transporters in skeletal muscle of humans with insulin-dependent diabetes mellitus: regulatory effects of metabolic factors. Kahn BB, Rosen AS, Bak JF, Andersen PH, Damsbo P, Lund S, Pedersen O, J Clin Endocrinol Metab 1992 74 1101 1109 10.1210/jc.74.5.1101 1569156