메뉴 건너뛰기




Volumn 6, Issue 12, 2005, Pages 1137-1142

Glucose transporter 4: Cycling, compartments and controversies

Author keywords

Glucose uptake; GLUT4 compartments; GLUT4 traffic; Insulin signalling; Type 2 diabetes mellitus

Indexed keywords

CBL PROTEIN; GLUCOSE; GLUCOSE TRANSPORTER 4; INSULIN; NUCLEOTIDE BINDING PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN KINASE C; RAB PROTEIN; RAB10 PROTEIN; RAB11 PROTEIN; RAB14 PROTEIN; RAB8 PROTEIN; SNARE PROTEIN; SYNAPTOBREVIN; SYNTAXIN; TRANSFERRIN RECEPTOR; UNCLASSIFIED DRUG;

EID: 28544450844     PISSN: 1469221X     EISSN: 14693178     Source Type: Journal    
DOI: 10.1038/sj.embor.7400584     Document Type: Review
Times cited : (200)

References (60)
  • 1
    • 0032504208 scopus 로고    scopus 로고
    • Endocytosis of the glucose transporter GLUT4 is mediated by the GTPase dynamin
    • Al-Hasani H, Hinck CS, Cushman SW (1998) Endocytosis of the glucose transporter GLUT4 is mediated by the GTPase dynamin. J Biol Chem 273: 17504-17510
    • (1998) J Biol Chem , vol.273 , pp. 17504-17510
    • Al-Hasani, H.1    Hinck, C.S.2    Cushman, S.W.3
  • 4
    • 18044393626 scopus 로고    scopus 로고
    • Insulin signal transduction in human skeletal muscle: Identifying the defects in Type II diabetes
    • Björnholm M, Zierath JR (2005) Insulin signal transduction in human skeletal muscle: Identifying the defects in Type II diabetes. Biochem Soc Trans 33: 354-357
    • (2005) Biochem Soc Trans , vol.33 , pp. 354-357
    • Björnholm, M.1    Zierath, J.R.2
  • 5
    • 0034774069 scopus 로고    scopus 로고
    • Activation of protein kinase Cz induces serine phosphorylation of VAMP2 in the GLUT4 compartment and increases glucose transport in skeletal muscle
    • Braiman L, Alt A, Kuroki T, Ohba M, Bak A, Tennenbaum T, Sampson SR (2001) Activation of protein kinase Cz induces serine phosphorylation of VAMP2 in the GLUT4 compartment and increases glucose transport in skeletal muscle. Mol Cell Biol 21: 7852-7861
    • (2001) Mol Cell Biol , vol.21 , pp. 7852-7861
    • Braiman, L.1    Alt, A.2    Kuroki, T.3    Ohba, M.4    Bak, A.5    Tennenbaum, T.6    Sampson, S.R.7
  • 6
    • 0036270751 scopus 로고    scopus 로고
    • Regulated transport of the glucose transporter GLUT4
    • Bryant NJ, Govers R, James DE (2002) Regulated transport of the glucose transporter GLUT4. Nat Rev Mol Cell Biol 3: 267-277
    • (2002) Nat Rev Mol Cell Biol , vol.3 , pp. 267-277
    • Bryant, N.J.1    Govers, R.2    James, D.E.3
  • 7
    • 0030464997 scopus 로고    scopus 로고
    • Insulin-stimulated translocation of GLUT4 glucose transporters requires SNARE-complex proteins
    • Cheatham B, Volchuk A, Kahn CR, Wang L, Rhodes CJ, Klip A (1996) Insulin-stimulated translocation of GLUT4 glucose transporters requires SNARE-complex proteins. Proc Natl Acad Sci USA 93: 15169-15173
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 15169-15173
    • Cheatham, B.1    Volchuk, A.2    Kahn, C.R.3    Wang, L.4    Rhodes, C.J.5    Klip, A.6
  • 9
    • 4744362873 scopus 로고    scopus 로고
    • Insulin stimulates the entry of GLUT4 into the endosomal recycling pathway by a quantal mechanism
    • Coster AC, Govers R, James DE (2004) Insulin stimulates the entry of GLUT4 into the endosomal recycling pathway by a quantal mechanism. Traffic 5: 763-771
    • (2004) Traffic , vol.5 , pp. 763-771
    • Coster, A.C.1    Govers, R.2    James, D.E.3
  • 11
    • 18044382930 scopus 로고    scopus 로고
    • Atypical protein kinase C in insulin action and insulin resistance
    • Farese RV, Sajan MP, Standaert ML (2005) Atypical protein kinase C in insulin action and insulin resistance. Biochem Soc Trans 33: 350-353
    • (2005) Biochem Soc Trans , vol.33 , pp. 350-353
    • Farese, R.V.1    Sajan, M.P.2    Standaert, M.L.3
  • 12
    • 0035941297 scopus 로고    scopus 로고
    • Insulin accelerates inter-endosomal GLUT4 traffic via phosphatidylinositol 3-kinase and protein kinase B
    • Foster LJ, Li D, Randhawa VK, Klip A (2001) Insulin accelerates inter-endosomal GLUT4 traffic via phosphatidylinositol 3-kinase and protein kinase B. J Biol Chem 276: 44212-44221
    • (2001) J Biol Chem , vol.276 , pp. 44212-44221
    • Foster, L.J.1    Li, D.2    Randhawa, V.K.3    Klip, A.4
  • 14
    • 3042841303 scopus 로고    scopus 로고
    • Insulin increases cell surface GLUT4 levels by dose dependently discharging GLUT4 into a cell surface recycling pathway
    • Govers R, Coster AC, James DE (2004) Insulin increases cell surface GLUT4 levels by dose dependently discharging GLUT4 into a cell surface recycling pathway. Mol Cell Biol 24: 6456-6466
    • (2004) Mol Cell Biol , vol.24 , pp. 6456-6466
    • Govers, R.1    Coster, A.C.2    James, D.E.3
  • 15
    • 14544271905 scopus 로고    scopus 로고
    • Positive and negative regulation of insulin signaling through IRS-1 phosphorylation
    • Gual P, Le Marchand-Brustel Y, Tanti JF (2005) Positive and negative regulation of insulin signaling through IRS-1 phosphorylation. Biochimie 87: 99-109
    • (2005) Biochimie , vol.87 , pp. 99-109
    • Gual, P.1    Le Marchand-Brustel, Y.2    Tanti, J.F.3
  • 16
    • 21744449171 scopus 로고    scopus 로고
    • Identification of 80K-H as a protein involved in GLUT4 vesicle trafficking
    • Hodgkinson CP, Mander A, Sale GJ (2005) Identification of 80K-H as a protein involved in GLUT4 vesicle trafficking. Biochem J 388: 785-793
    • (2005) Biochem J , vol.388 , pp. 785-793
    • Hodgkinson, C.P.1    Mander, A.2    Sale, G.J.3
  • 17
    • 19644372736 scopus 로고    scopus 로고
    • p115 interacts with the GLUT4 vesicle protein, IRAP, and plays a critical role in insulin-stimulated GLUT4 translocation
    • Hosaka T, Brooks CC, Presman E, Kim SK, Zhang Z, Breen M, Gross DN, Sztul E, Pilch PF (2005) p115 interacts with the GLUT4 vesicle protein, IRAP, and plays a critical role in insulin-stimulated GLUT4 translocation. Mol Biol Cell 16: 2882-2890
    • (2005) Mol Biol Cell , vol.16 , pp. 2882-2890
    • Hosaka, T.1    Brooks, C.C.2    Presman, E.3    Kim, S.K.4    Zhang, Z.5    Breen, M.6    Gross, D.N.7    Sztul, E.8    Pilch, P.F.9
  • 18
    • 0035818483 scopus 로고    scopus 로고
    • Insulin can regulate GLUT4 internalization by signaling to Rab5 and the motor protein dynein
    • Huang J, Imamura T, Olefsky JM (2001) Insulin can regulate GLUT4 internalization by signaling to Rab5 and the motor protein dynein. Proc Natl Acad Sci USA 98: 13084-13089
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 13084-13089
    • Huang, J.1    Imamura, T.2    Olefsky, J.M.3
  • 19
    • 0038451252 scopus 로고    scopus 로고
    • Insulin-induced GLUT4 translocation involves protein kinase C-λ-mediated functional coupling between Rab4 and the motor protein kinesin
    • Imamura T, Huang J, Usui I, Satoh H, Bever J, Olefsky JM (2003) Insulin-induced GLUT4 translocation involves protein kinase C-λ-mediated functional coupling between Rab4 and the motor protein kinesin. Mol Cell Biol 23: 4892-4900
    • (2003) Mol Cell Biol , vol.23 , pp. 4892-4900
    • Imamura, T.1    Huang, J.2    Usui, I.3    Satoh, H.4    Bever, J.5    Olefsky, J.M.6
  • 20
    • 23344431984 scopus 로고    scopus 로고
    • Insulin regulates the membrane arrival, fusion, and C-terminal unmasking of glucose transporter-4 via distinct phosphoinositides
    • Ishiki M, Randhawa VK, Poon V, Jebailey L, Klip A (2005) Insulin regulates the membrane arrival, fusion, and C-terminal unmasking of glucose transporter-4 via distinct phosphoinositides. J Biol Chem 280: 28792-28802
    • (2005) J Biol Chem , vol.280 , pp. 28792-28802
    • Ishiki, M.1    Randhawa, V.K.2    Poon, V.3    Jebailey, L.4    Klip, A.5
  • 21
    • 0842312945 scopus 로고    scopus 로고
    • Skeletal muscle cells and adipocytes differ in their reliance on TC10 and Rac for insulin-induced actin remodeling
    • JeBailey L, Rudich A, Huang X, Di Ciano-Oliveira C, Kapus A, Klip A (2004) Skeletal muscle cells and adipocytes differ in their reliance on TC10 and Rac for insulin-induced actin remodeling. Mol Endocrinol 18: 359-372
    • (2004) Mol Endocrinol , vol.18 , pp. 359-372
    • JeBailey, L.1    Rudich, A.2    Huang, X.3    Di Ciano-Oliveira, C.4    Kapus, A.5    Klip, A.6
  • 23
    • 0032566652 scopus 로고    scopus 로고
    • Expression of a dominant interfering dynamin mutant in 3T3L1 adipocytes inhibits GLUT4 endocytosis without affecting insulin signaling
    • Kao AW, Ceresa BP, Santeler SR, Pessin JE (1998) Expression of a dominant interfering dynamin mutant in 3T3L1 adipocytes inhibits GLUT4 endocytosis without affecting insulin signaling. J Biol Chem 273: 25450-25457
    • (1998) J Biol Chem , vol.273 , pp. 25450-25457
    • Kao, A.W.1    Ceresa, B.P.2    Santeler, S.R.3    Pessin, J.E.4
  • 24
    • 0742288016 scopus 로고    scopus 로고
    • GLUT4 is retained by an intracellular cycle of vesicle formation and fusion with endosomes
    • Karylowski O, Zeigerer A, Cohen A, McGraw TE (2004) GLUT4 is retained by an intracellular cycle of vesicle formation and fusion with endosomes. Mol Biol Cell 15: 870-882
    • (2004) Mol Biol Cell , vol.15 , pp. 870-882
    • Karylowski, O.1    Zeigerer, A.2    Cohen, A.3    McGraw, T.E.4
  • 25
    • 1542778629 scopus 로고    scopus 로고
    • The insulin-regulated aminopeptidase: A companion and regulator of GLUT4
    • Keller SR (2003) The insulin-regulated aminopeptidase: A companion and regulator of GLUT4. Front Biosci 8: S410-s420
    • (2003) Front Biosci , vol.8
    • Keller, S.R.1
  • 26
    • 27744584659 scopus 로고    scopus 로고
    • Insulin signaling meets vesicle traffic of GLUT4 at a plasma-membrane-activated fusion step
    • Koumanov F, Jin B, Yang J, Holman GD (2005) Insulin signaling meets vesicle traffic of GLUT4 at a plasma-membrane-activated fusion step. Cell Metab 2: 179-189
    • (2005) Cell Metab , vol.2 , pp. 179-189
    • Koumanov, F.1    Jin, B.2    Yang, J.3    Holman, G.D.4
  • 27
    • 28544444987 scopus 로고    scopus 로고
    • Characterisation of the role of the RabGAP AS160 in insulin-regulated GLUT4 trafficking
    • [epub ahead of print]
    • Larance M et al (2005) Characterisation of the role of the RabGAP AS160 in insulin-regulated GLUT4 trafficking. J Biol Chem [epub ahead of print]
    • (2005) J Biol Chem
    • Larance, M.1
  • 28
    • 0035933728 scopus 로고    scopus 로고
    • Hyperosmolarity reduces GLUT4 endocytosis and increases its exocytosis from a VAMP2-independent pool in 16 muscle cells
    • Li D, Randhawa VK, Patel N, Hayashi M, Klip A (2001) Hyperosmolarity reduces GLUT4 endocytosis and increases its exocytosis from a VAMP2-independent pool in 16 muscle cells. J Biol Chem 276: 22883-22891
    • (2001) J Biol Chem , vol.276 , pp. 22883-22891
    • Li, D.1    Randhawa, V.K.2    Patel, N.3    Hayashi, M.4    Klip, A.5
  • 29
    • 18844405437 scopus 로고    scopus 로고
    • Insulin stimulates the halting, tethering, and fusion of mobile GLUT4 vesicles in rat adipose cells
    • Lizunov VA, Matsumoto H, Zimmerberg J, Cushman SW, Frolov VA (2005) Insulin stimulates the halting, tethering, and fusion of mobile GLUT4 vesicles in rat adipose cells. J Cell Biol 169: 481-489
    • (2005) J Cell Biol , vol.169 , pp. 481-489
    • Lizunov, V.A.1    Matsumoto, H.2    Zimmerberg, J.3    Cushman, S.W.4    Frolov, V.A.5
  • 30
    • 0042466604 scopus 로고    scopus 로고
    • Insulin induces phosphatidylinositol-3-phosphate formation through TC10 activation
    • Maffucci T, Brancaccio A, Piccolo E, Stein RC, Falasca M (2003) Insulin induces phosphatidylinositol-3-phosphate formation through TC10 activation. EMBO J 22: 4178-4189
    • (2003) EMBO J , vol.22 , pp. 4178-4189
    • Maffucci, T.1    Brancaccio, A.2    Piccolo, E.3    Stein, R.C.4    Falasca, M.5
  • 31
    • 0034537706 scopus 로고    scopus 로고
    • Immunoelectron microscopic evidence that GLUT4 translocation explains the stimulation of glucose transport in isolated rat white adipose cells
    • Malide D, Ramm G, Cushman SW, Slot JW (2000) Immunoelectron microscopic evidence that GLUT4 translocation explains the stimulation of glucose transport in isolated rat white adipose cells. J Cell Sci 113: 4203-4210
    • (2000) J Cell Sci , vol.113 , pp. 4203-4210
    • Malide, D.1    Ramm, G.2    Cushman, S.W.3    Slot, J.W.4
  • 32
    • 0031891004 scopus 로고    scopus 로고
    • Vesicle-associated membrane protein 2 plays a specific role in the insulin-dependent trafficking of the facilitative glucose transporter GLUT4 in 3T3-L1 adipocytes
    • Martin LB, Shewan A, Millar CA, Gould GW, James DE (1998) Vesicle-associated membrane protein 2 plays a specific role in the insulin-dependent trafficking of the facilitative glucose transporter GLUT4 in 3T3-L1 adipocytes. J Biol Chem 273: 1444-1452
    • (1998) J Biol Chem , vol.273 , pp. 1444-1452
    • Martin, L.B.1    Shewan, A.2    Millar, C.A.3    Gould, G.W.4    James, D.E.5
  • 33
    • 0029741442 scopus 로고    scopus 로고
    • The glucose transporter (GLUT-4) and vesicle-associated membrane protein-2 (VAMP-2) are segregated from recycling endosomes in insulin-sensitive cells
    • Martin S, Tellam J, Livingstone C, Slot JW, Gould GW, James DE (1996) The glucose transporter (GLUT-4) and vesicle-associated membrane protein-2 (VAMP-2) are segregated from recycling endosomes in insulin-sensitive cells. J Cell Biol 134: 625-635
    • (1996) J Cell Biol , vol.134 , pp. 625-635
    • Martin, S.1    Tellam, J.2    Livingstone, C.3    Slot, J.W.4    Gould, G.W.5    James, D.E.6
  • 34
    • 26844573782 scopus 로고    scopus 로고
    • AS160, the Akt substrate regulating GLUT4 translocation, has a functional Rab GTPase activating protein domain
    • Miinea CP, Sano H, Kane S, Sano E, Fukuda M, Peranen J, Lane WS, Lienhard GE (2005) AS160, the Akt substrate regulating GLUT4 translocation, has a functional Rab GTPase activating protein domain. Biochem J 391: 87-93
    • (2005) Biochem J , vol.391 , pp. 87-93
    • Miinea, C.P.1    Sano, H.2    Kane, S.3    Sano, E.4    Fukuda, M.5    Peranen, J.6    Lane, W.S.7    Lienhard, G.E.8
  • 35
    • 0030937422 scopus 로고    scopus 로고
    • Syntaxin 4, VAMP2, and/or VAMP3/cellubrevin are functional target membrane and vesicle SNAP receptors for insulin-stimulated GLUT4 translocation in adipocytes
    • Olson AL, Knight JB, Pessin JE (1997) Syntaxin 4, VAMP2, and/or VAMP3/ cellubrevin are functional target membrane and vesicle SNAP receptors for insulin-stimulated GLUT4 translocation in adipocytes. Mol Cell Biol 17: 2425-2435
    • (1997) Mol Cell Biol , vol.17 , pp. 2425-2435
    • Olson, A.L.1    Knight, J.B.2    Pessin, J.E.3
  • 36
    • 28544450587 scopus 로고    scopus 로고
    • Cellular location of insulin-triggered signals and implications for glucose uptake
    • (in the press)
    • Patel N, Huang C, Klip A (2005) Cellular location of insulin-triggered signals and implications for glucose uptake. Pflugers Arch (in the press)
    • (2005) Pflugers Arch
    • Patel, N.1    Huang, C.2    Klip, A.3
  • 37
    • 0036117713 scopus 로고    scopus 로고
    • Exploring the whereabouts of GLUT4 in skeletal muscle
    • (review)
    • Ploug T, Ralston E (2002) Exploring the whereabouts of GLUT4 in skeletal muscle (review). Mol Membr Biol 19: 39-49
    • (2002) Mol Membr Biol , vol.19 , pp. 39-49
    • Ploug, T.1    Ralston, E.2
  • 38
    • 9444251776 scopus 로고    scopus 로고
    • Insulin and hypertonicity recruit GLUT4 to the plasma membrane of muscle cells by using N-ethylmaleimide-sensitive factor-dependent SNARE mechanisms but different v-SNAREs: Role of TI-VAMP
    • Randhawa VK, Thong FS, Lim DY, Li D, Garg RR, Rudge R, Galli T, Rudich A, Klip A (2004) Insulin and hypertonicity recruit GLUT4 to the plasma membrane of muscle cells by using N-ethylmaleimide-sensitive factor-dependent SNARE mechanisms but different v-SNAREs: Role of TI-VAMP. Mol Biol Cell 15: 5565-5573
    • (2004) Mol Biol Cell , vol.15 , pp. 5565-5573
    • Randhawa, V.K.1    Thong, F.S.2    Lim, D.Y.3    Li, D.4    Garg, R.R.5    Rudge, R.6    Galli, T.7    Rudich, A.8    Klip, A.9
  • 39
    • 0041659271 scopus 로고    scopus 로고
    • Push/pull mechanisms of GLUT4 traffic in muscle cells
    • Rudich A, Klip A (2003) Push/pull mechanisms of GLUT4 traffic in muscle cells. Acta Physiol Scand 178: 297-308
    • (2003) Acta Physiol Scand , vol.178 , pp. 297-308
    • Rudich, A.1    Klip, A.2
  • 40
    • 0036470213 scopus 로고    scopus 로고
    • Insulin signaling pathways in time and space
    • Saltiel AR, Pessin JE (2002) Insulin signaling pathways in time and space. Trends Cell Biol 12: 65-71
    • (2002) Trends Cell Biol , vol.12 , pp. 65-71
    • Saltiel, A.R.1    Pessin, J.E.2
  • 41
    • 19744378802 scopus 로고    scopus 로고
    • Synip phosphorylation does not regulate insulin-stimulated GLUT4 translocation
    • Sano H, Kane S, Sano E, Lienhard GE (2005) Synip phosphorylation does not regulate insulin-stimulated GLUT4 translocation. Biochem Biophys Res Commun 332: 880-884
    • (2005) Biochem Biophys Res Commun , vol.332 , pp. 880-884
    • Sano, H.1    Kane, S.2    Sano, E.3    Lienhard, G.E.4
  • 43
    • 0027290847 scopus 로고
    • Use of bismannose photolabel to elucidate insulin-regulated GLUT4 subcellular trafficking kinetics in rat adipose cells. Evidence that exocytosis is a critical site of hormone action
    • Satoh S, Nishimura H, Clark AE, Kozka IJ, Vannucci SJ, Simpson IA, Quon MJ, Cushman SW, Holman GD (1993) Use of bismannose photolabel to elucidate insulin-regulated GLUT4 subcellular trafficking kinetics in rat adipose cells. Evidence that exocytosis is a critical site of hormone action. J Biol Chem 268: 17820-17829
    • (1993) J Biol Chem , vol.268 , pp. 17820-17829
    • Satoh, S.1    Nishimura, H.2    Clark, A.E.3    Kozka, I.J.4    Vannucci, S.J.5    Simpson, I.A.6    Quon, M.J.7    Cushman, S.W.8    Holman, G.D.9
  • 44
    • 0037341432 scopus 로고    scopus 로고
    • GLUT4 recycles via a trans-Golgi network (TGN) subdomain enriched in syntaxins 6 and 16 but not TGN38: Involvement of an acidic targeting motif
    • Shewan AM, van Dam EM, Martin S, Luen TB, Hong W, Bryant NJ, James DE (2003) GLUT4 recycles via a trans-Golgi network (TGN) subdomain enriched in syntaxins 6 and 16 but not TGN38: Involvement of an acidic targeting motif. Mol Biol Cell 14: 973-986
    • (2003) Mol Biol Cell , vol.14 , pp. 973-986
    • Shewan, A.M.1    van Dam, E.M.2    Martin, S.3    Luen, T.B.4    Hong, W.5    Bryant, N.J.6    James, D.E.7
  • 45
    • 21344439799 scopus 로고    scopus 로고
    • Sortilin is essential and sufficient for the formation of Glut4 storage vesicles in 3T3-L1 adipocytes
    • Shi J, Kandror KV (2005) Sortilin is essential and sufficient for the formation of Glut4 storage vesicles in 3T3-L1 adipocytes. Dev Cell 9: 99-108
    • (2005) Dev Cell , vol.9 , pp. 99-108
    • Shi, J.1    Kandror, K.V.2
  • 46
    • 0025761381 scopus 로고
    • Immunolocalization of the insulin regulatable glucose transporter in brown adipose tissue of the rat
    • Slot JW, Geuze HJ, Gigengack S, Lienhard GE, James DE (1991) Immunolocalization of the insulin regulatable glucose transporter in brown adipose tissue of the rat. J Cell Biol 113: 123-135
    • (1991) J Cell Biol , vol.113 , pp. 123-135
    • Slot, J.W.1    Geuze, H.J.2    Gigengack, S.3    Lienhard, G.E.4    James, D.E.5
  • 47
    • 2942556680 scopus 로고    scopus 로고
    • The synaptic vesicle cycle
    • Südhof TC (2004) The synaptic vesicle cycle. Annu Rev Neurosci 27: 509-547
    • (2004) Annu Rev Neurosci , vol.27 , pp. 509-547
    • Südhof, T.C.1
  • 48
    • 24044468429 scopus 로고    scopus 로고
    • Turning signals on and off: GLUT4 traffic in the insulin-signaling highway
    • Thong FS, Dugani CB, Klip A (2005) Turning signals on and off: GLUT4 traffic in the insulin-signaling highway. Physiology (Bethesda) 20: 271-284
    • (2005) Physiology (Bethesda) , vol.20 , pp. 271-284
    • Thong, F.S.1    Dugani, C.B.2    Klip, A.3
  • 49
    • 9444259803 scopus 로고    scopus 로고
    • Insulin but not PDGF relies on actin remodeling and on VAMP2 for GLUT4 translocation in myoblasts
    • Török D, Patel N, Jebailey L, Thong FS, Randhawa VK, Klip A, Rudich A (2004) Insulin but not PDGF relies on actin remodeling and on VAMP2 for GLUT4 translocation in myoblasts. J Cell Sci 117: 5447-5455
    • (2004) J Cell Sci , vol.117 , pp. 5447-5455
    • Török, D.1    Patel, N.2    Jebailey, L.3    Thong, F.S.4    Randhawa, V.K.5    Klip, A.6    Rudich, A.7
  • 50
    • 15244356165 scopus 로고    scopus 로고
    • Akt activation is required at a late stage of insulin-induced GLUT4 translocation to the plasma membrane
    • van Dam EM, Govers R, James DE (2005) Akt activation is required at a late stage of insulin-induced GLUT4 translocation to the plasma membrane. Mol Endocrinol 19: 1067-1077
    • (2005) Mol Endocrinol , vol.19 , pp. 1067-1077
    • van Dam, E.M.1    Govers, R.2    James, D.E.3
  • 51
    • 0032478621 scopus 로고    scopus 로고
    • Perturbation of dynamin II with an amphiphysin SH3 domain increases GLUT4 glucose transporters at the plasma membrane in 3T3-L1 adipocytes. Dynamin II participates in GLUT4 endocytosis
    • Volchuk A, Narine S, Foster LJ, Grabs D, De Camilli P, Klip A (1998) Perturbation of dynamin II with an amphiphysin SH3 domain increases GLUT4 glucose transporters at the plasma membrane in 3T3-L1 adipocytes. Dynamin II participates in GLUT4 endocytosis. J Biol Chem 273: 8169-8176
    • (1998) J Biol Chem , vol.273 , pp. 8169-8176
    • Volchuk, A.1    Narine, S.2    Foster, L.J.3    Grabs, D.4    De Camilli, P.5    Klip, A.6
  • 52
    • 10344236432 scopus 로고    scopus 로고
    • Regulated membrane trafficking of the insulin-responsive glucose transporter 4 in adipocytes
    • Watson RT, Kanzaki M, Pessin JE (2004a) Regulated membrane trafficking of the insulin-responsive glucose transporter 4 in adipocytes. Endocr Rev 25: 177-204
    • (2004) Endocr Rev , vol.25 , pp. 177-204
    • Watson, R.T.1    Kanzaki, M.2    Pessin, J.E.3
  • 55
    • 0042818205 scopus 로고    scopus 로고
    • Tomosyn interacts with the t-SNAREs syntaxin4 and SNAP23 and plays a role in insulin-stimulated GLUT4 translocation
    • Widberg CH, Bryant NJ, Girotti M, Rea S, James DE (2003) Tomosyn interacts with the t-SNAREs syntaxin4 and SNAP23 and plays a role in insulin-stimulated GLUT4 translocation. J Biol Chem 278: 35093-35101
    • (2003) J Biol Chem , vol.278 , pp. 35093-35101
    • Widberg, C.H.1    Bryant, N.J.2    Girotti, M.3    Rea, S.4    James, D.E.5
  • 57
    • 0030059569 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase acts at an intracellular membrane site to enhance GLUT4 exocytosis in 3T3-L1 cells
    • Yang J, Clarke JF, Ester CJ, Young PW, Kasuga M, Holman GD (1996) Phosphatidylinositol 3-kinase acts at an intracellular membrane site to enhance GLUT4 exocytosis in 3T3-L1 cells. Biochem J 313: 125-132
    • (1996) Biochem J , vol.313 , pp. 125-132
    • Yang, J.1    Clarke, J.F.2    Ester, C.J.3    Young, P.W.4    Kasuga, M.5    Holman, G.D.6
  • 59
    • 4644300287 scopus 로고    scopus 로고
    • Insulin stimulation of GLUT4 exocytosis, but not its inhibition of endocytosis, is dependent on RabGAP AS160
    • Zeigerer A, McBrayer MK, McGraw TE (2004) Insulin stimulation of GLUT4 exocytosis, but not its inhibition of endocytosis, is dependent on RabGAP AS160. Mol Biol Cell 15: 4406-4415
    • (2004) Mol Biol Cell , vol.15 , pp. 4406-4415
    • Zeigerer, A.1    McBrayer, M.K.2    McGraw, T.E.3
  • 60
    • 0035856920 scopus 로고    scopus 로고
    • Global and societal implications of the diabetes epidemic
    • Zimmet P, Alberti KG, Shaw J (2001) Global and societal implications of the diabetes epidemic. Nature 414: 782-787
    • (2001) Nature , vol.414 , pp. 782-787
    • Zimmet, P.1    Alberti, K.G.2    Shaw, J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.