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Volumn 215, Issue 3, 2012, Pages 193-200

A chronic oral exposure of pigs with deoxynivalenol partially prevents the acute effects of lipopolysaccharides on hepatic histopathology and blood clinical chemistry

Author keywords

Blood chemistry; Deoxynivalenol; Escherichia coli lipopolysaccharide; Histopathology; Porcine liver

Indexed keywords

ALBUMIN; ASPARTATE AMINOTRANSFERASE; BILIRUBIN; DO 156; GAMMA GLUTAMYLTRANSFERASE; GLUTAMATE DEHYDROGENASE; LIPOPOLYSACCHARIDE; SODIUM CHLORIDE; UNCLASSIFIED DRUG; VOMITOXIN;

EID: 84869875397     PISSN: 03784274     EISSN: 18793169     Source Type: Journal    
DOI: 10.1016/j.toxlet.2012.10.009     Document Type: Article
Times cited : (22)

References (46)
  • 3
    • 0036109542 scopus 로고    scopus 로고
    • L-Arginine supplementation in pigs decreases liver protein turnover and increases hindquarter protein turnover both during and after endotoxemia
    • Bruins M.J., Soeters P.B., Lamers W.H., Deutz N.E. l-Arginine supplementation in pigs decreases liver protein turnover and increases hindquarter protein turnover both during and after endotoxemia. American Journal of Clinical Nutrition 2002, 75:1031-1044.
    • (2002) American Journal of Clinical Nutrition , vol.75 , pp. 1031-1044
    • Bruins, M.J.1    Soeters, P.B.2    Lamers, W.H.3    Deutz, N.E.4
  • 4
    • 0023898074 scopus 로고
    • Acute inflammation and microthrombosis induced by endotoxin, interleukin-1, and tumor necrosis factor and their implication in gram-negative infection
    • Cybulsky M.I., Chan M.K., Movat H.Z. Acute inflammation and microthrombosis induced by endotoxin, interleukin-1, and tumor necrosis factor and their implication in gram-negative infection. Laboratory Investigation 1988, 58:365-378.
    • (1988) Laboratory Investigation , vol.58 , pp. 365-378
    • Cybulsky, M.I.1    Chan, M.K.2    Movat, H.Z.3
  • 5
    • 0032957479 scopus 로고    scopus 로고
    • Intestinal and hepatic perfusion and metabolism in hypodynamic endotoxic shock. Effects of nitric oxide synthase inhibition
    • Dahm P.L., Thorne J., Myhre E., Grins E., Martensson L., Blomquist S. Intestinal and hepatic perfusion and metabolism in hypodynamic endotoxic shock. Effects of nitric oxide synthase inhibition. Acta Anaesthesiologica Scandinavica 1999, 43:56-63.
    • (1999) Acta Anaesthesiologica Scandinavica , vol.43 , pp. 56-63
    • Dahm, P.L.1    Thorne, J.2    Myhre, E.3    Grins, E.4    Martensson, L.5    Blomquist, S.6
  • 7
    • 32844469977 scopus 로고    scopus 로고
    • Lipopolysaccharide signaling in endothelial cells
    • Dauphinee S.M., Karsan A. Lipopolysaccharide signaling in endothelial cells. Laboratory Investigation 2006, 86:9-22.
    • (2006) Laboratory Investigation , vol.86 , pp. 9-22
    • Dauphinee, S.M.1    Karsan, A.2
  • 8
    • 79952158502 scopus 로고    scopus 로고
    • Vulnerability of polarised intestinal porcine epithelial cells to mycotoxin deoxynivalenol depends on the route of application
    • Diesing A.K., Nossol C., Dänicke S., Walk N., Post A., Kahlert S., Rothkötter H.J., Kluess J. Vulnerability of polarised intestinal porcine epithelial cells to mycotoxin deoxynivalenol depends on the route of application. PLoS ONE 2011, 6:e17472.
    • (2011) PLoS ONE , vol.6
    • Diesing, A.K.1    Nossol, C.2    Dänicke, S.3    Walk, N.4    Post, A.5    Kahlert, S.6    Rothkötter, H.J.7    Kluess, J.8
  • 9
    • 67649401662 scopus 로고    scopus 로고
    • Interactions of deoxynivalenol and lipopolysaccharides on cytotoxicity protein synthesis and metabolism of DON in porcine hepatocytes and Kupffer cell enriched hepatocyte cultures
    • Döll S., Schrickx J.A., Valenta H., Dänicke S., Fink-Gremmels J. Interactions of deoxynivalenol and lipopolysaccharides on cytotoxicity protein synthesis and metabolism of DON in porcine hepatocytes and Kupffer cell enriched hepatocyte cultures. Toxicology Letters 2009, 189:121-129.
    • (2009) Toxicology Letters , vol.189 , pp. 121-129
    • Döll, S.1    Schrickx, J.A.2    Valenta, H.3    Dänicke, S.4    Fink-Gremmels, J.5
  • 10
    • 68349144573 scopus 로고    scopus 로고
    • Interactions of deoxynivalenol and lipopolysaccharides on cytokine excretion and mRNA expression in porcine hepatocytes and Kupffer cell enriched hepatocyte cultures
    • Döll S., Schrickx J.A., Dänicke S., Fink-Gremmels J. Interactions of deoxynivalenol and lipopolysaccharides on cytokine excretion and mRNA expression in porcine hepatocytes and Kupffer cell enriched hepatocyte cultures. Toxicology Letters 2009, 190:96-105.
    • (2009) Toxicology Letters , vol.190 , pp. 96-105
    • Döll, S.1    Schrickx, J.A.2    Dänicke, S.3    Fink-Gremmels, J.4
  • 11
    • 8844247487 scopus 로고    scopus 로고
    • Opinion of the scientific panel on contaminants in the food chain on a request from the commission related to deoxynivalenol (DON) as undesirable substance in animal feed
    • EFSA
    • EFSA Opinion of the scientific panel on contaminants in the food chain on a request from the commission related to deoxynivalenol (DON) as undesirable substance in animal feed. The EFSA Journal 2004, 73:1-42.
    • (2004) The EFSA Journal , vol.73 , pp. 1-42
  • 12
    • 0023103518 scopus 로고
    • Protein synthesis inhibition by 8-oxo-12,13-epoxytrichothecenes
    • Ehrlich K.C., Daigle K.W. Protein synthesis inhibition by 8-oxo-12,13-epoxytrichothecenes. Biochimica et Biophysica Acta 1987, 923:206-213.
    • (1987) Biochimica et Biophysica Acta , vol.923 , pp. 206-213
    • Ehrlich, K.C.1    Daigle, K.W.2
  • 14
    • 0031842549 scopus 로고    scopus 로고
    • Endotoxaemic liver injury in a porcine model-relation to tumour necrosis factor-alpha release and survival
    • Eriksson M., Larsson A., Lundkvist K., Loof L. Endotoxaemic liver injury in a porcine model-relation to tumour necrosis factor-alpha release and survival. Scandinavian Journal of Infectious Diseases 1998, 30:169-172.
    • (1998) Scandinavian Journal of Infectious Diseases , vol.30 , pp. 169-172
    • Eriksson, M.1    Larsson, A.2    Lundkvist, K.3    Loof, L.4
  • 16
    • 0345487501 scopus 로고    scopus 로고
    • Lipopolysaccharide induces apoptosis in a bovine endothelial cell line via a soluble CD14 dependent pathway
    • Frey E.A., Finlay B.B. Lipopolysaccharide induces apoptosis in a bovine endothelial cell line via a soluble CD14 dependent pathway. Microbial Pathogenesis 1998, 24:101-109.
    • (1998) Microbial Pathogenesis , vol.24 , pp. 101-109
    • Frey, E.A.1    Finlay, B.B.2
  • 17
    • 39149120354 scopus 로고    scopus 로고
    • Ausschuss für Bedarfsnormen der Gesellschaft für Ernährungsphysiologie, Frankfurt/Main.,. GfE
    • GfE Empfehlungen zur Energie- und Nährstoffversorgung von Schweinen 2006, Ausschuss für Bedarfsnormen der Gesellschaft für Ernährungsphysiologie, Frankfurt/Main.
    • (2006) Empfehlungen zur Energie- und Nährstoffversorgung von Schweinen
  • 18
    • 33645872701 scopus 로고    scopus 로고
    • Bioavailability of the Fusarium toxin deoxynivalenol (DON) from naturally contaminated wheat for the pig
    • Goyarts T., Dänicke S. Bioavailability of the Fusarium toxin deoxynivalenol (DON) from naturally contaminated wheat for the pig. Toxicology Letters 2006, 163:171-182.
    • (2006) Toxicology Letters , vol.163 , pp. 171-182
    • Goyarts, T.1    Dänicke, S.2
  • 19
    • 33749582285 scopus 로고    scopus 로고
    • Effects of the Fusarium toxin deoxynivalenol from naturally contaminated wheat given subchronically or as one single dose on the in vivo protein synthesis of peripheral blood lymphocytes and plasma proteins in the pig
    • Goyarts T., Grove N., Dänicke S. Effects of the Fusarium toxin deoxynivalenol from naturally contaminated wheat given subchronically or as one single dose on the in vivo protein synthesis of peripheral blood lymphocytes and plasma proteins in the pig. Food and Chemical Toxicology 2006, 44:1953-1965.
    • (2006) Food and Chemical Toxicology , vol.44 , pp. 1953-1965
    • Goyarts, T.1    Grove, N.2    Dänicke, S.3
  • 20
    • 34250857361 scopus 로고    scopus 로고
    • On the transfer of the Fusarium toxins deoxynivalenol (DON) and zearalenone (ZON) from sows to their fetuses during days 35-70 of gestation
    • Goyarts T., Dänicke S., Brüssow K.P., Valenta H., Ueberschar K.H., Tiemann U. On the transfer of the Fusarium toxins deoxynivalenol (DON) and zearalenone (ZON) from sows to their fetuses during days 35-70 of gestation. Toxicology Letters 2007, 171:38-49.
    • (2007) Toxicology Letters , vol.171 , pp. 38-49
    • Goyarts, T.1    Dänicke, S.2    Brüssow, K.P.3    Valenta, H.4    Ueberschar, K.H.5    Tiemann, U.6
  • 23
    • 31444448616 scopus 로고    scopus 로고
    • LPS priming potentiates and prolongs proinflammatory cytokine response to the trichothecene deoxynivalenol in the mouse
    • Islam Z., Pestka J.J. LPS priming potentiates and prolongs proinflammatory cytokine response to the trichothecene deoxynivalenol in the mouse. Toxicology and Applied Pharmacology 2006, 211:53-63.
    • (2006) Toxicology and Applied Pharmacology , vol.211 , pp. 53-63
    • Islam, Z.1    Pestka, J.J.2
  • 24
    • 80052393337 scopus 로고    scopus 로고
    • Propolis derivatives inhibit the systemic inflammatory response and protect hepatic and neuronal cells in acute septic shock
    • Korish A.A., Arafa M.M. Propolis derivatives inhibit the systemic inflammatory response and protect hepatic and neuronal cells in acute septic shock. Brazilian Journal of Infectious Diseases 2011, 15:332-338.
    • (2011) Brazilian Journal of Infectious Diseases , vol.15 , pp. 332-338
    • Korish, A.A.1    Arafa, M.M.2
  • 30
    • 77952704260 scopus 로고    scopus 로고
    • Induction of apoptotic lesions in liver and lymphoid tissues and modulation of cytokine mRNA expression by acute exposure to deoxynivalenol in piglets
    • Mikami O., Yamaguchi H., Murata H., Nakajima Y., Miyazaki S. Induction of apoptotic lesions in liver and lymphoid tissues and modulation of cytokine mRNA expression by acute exposure to deoxynivalenol in piglets. Journal of Veterinary Science 2010, 11:107-113.
    • (2010) Journal of Veterinary Science , vol.11 , pp. 107-113
    • Mikami, O.1    Yamaguchi, H.2    Murata, H.3    Nakajima, Y.4    Miyazaki, S.5
  • 31
    • 18944367082 scopus 로고    scopus 로고
    • An acute inflammatory response alters bone homeostasis body composition, and the humoral immune response of broiler chickens
    • Mireles A.J., Kim S.M., Klasing K.C. An acute inflammatory response alters bone homeostasis body composition, and the humoral immune response of broiler chickens. Poultry Science 2005, 84:553-560.
    • (2005) Poultry Science , vol.84 , pp. 553-560
    • Mireles, A.J.1    Kim, S.M.2    Klasing, K.C.3
  • 32
    • 0030848071 scopus 로고    scopus 로고
    • Effect of growth hormone or chromium picolinate on swine metabolism and inflammatory cytokine production after endotoxin challenge exposure
    • Myers M.J., Farrell D.E., Evock-Clover C.M., McDonald M.W., Steele N.C. Effect of growth hormone or chromium picolinate on swine metabolism and inflammatory cytokine production after endotoxin challenge exposure. American Journal of Veterinary Research 1997, 58:594-600.
    • (1997) American Journal of Veterinary Research , vol.58 , pp. 594-600
    • Myers, M.J.1    Farrell, D.E.2    Evock-Clover, C.M.3    McDonald, M.W.4    Steele, N.C.5
  • 34
    • 70849100264 scopus 로고    scopus 로고
    • Mechanisms of deoxynivalenol-induced gene expression and apoptosis
    • Pestka J.J. Mechanisms of deoxynivalenol-induced gene expression and apoptosis. Food Additives and Contaminants 2008, 25:1128-1140.
    • (2008) Food Additives and Contaminants , vol.25 , pp. 1128-1140
    • Pestka, J.J.1
  • 35
    • 77957802278 scopus 로고    scopus 로고
    • Deoxynivalenol: mechanisms of action, human exposure, and toxicological relevance
    • Pestka J.J. Deoxynivalenol: mechanisms of action, human exposure, and toxicological relevance. Archives of Toxicology 2010, 84:663-679.
    • (2010) Archives of Toxicology , vol.84 , pp. 663-679
    • Pestka, J.J.1
  • 36
    • 79952099319 scopus 로고    scopus 로고
    • Deoxynivalenol-induced proinflammatory gene expression: mechanisms and pathological sequelae
    • Pestka J.J. Deoxynivalenol-induced proinflammatory gene expression: mechanisms and pathological sequelae. Toxins (Basel) 2010, 2:1300-1317.
    • (2010) Toxins (Basel) , vol.2 , pp. 1300-1317
    • Pestka, J.J.1
  • 37
    • 0031951337 scopus 로고    scopus 로고
    • Limulus antilipopolysaccharide factor prevents mortality late in the course of endotoxemia
    • Roth R.I., Su D., Child A.H., Wainwright N.R., Levin J. Limulus antilipopolysaccharide factor prevents mortality late in the course of endotoxemia. Journal of Infectious Diseases 1998, 177:388-394.
    • (1998) Journal of Infectious Diseases , vol.177 , pp. 388-394
    • Roth, R.I.1    Su, D.2    Child, A.H.3    Wainwright, N.R.4    Levin, J.5
  • 38
    • 77957187583 scopus 로고
    • Influence of low-level exposure to Fusarium mycotoxins on selected immunological and hematological parameters in young swine
    • Rotter B.A., Thompson B.K., Lessard M., Trenholm H.L., Tryphonas H. Influence of low-level exposure to Fusarium mycotoxins on selected immunological and hematological parameters in young swine. Fundamental and Applied Toxicology 1994, 23:117-124.
    • (1994) Fundamental and Applied Toxicology , vol.23 , pp. 117-124
    • Rotter, B.A.1    Thompson, B.K.2    Lessard, M.3    Trenholm, H.L.4    Tryphonas, H.5
  • 41
    • 33745212442 scopus 로고    scopus 로고
    • Effects of diets with cereal grains contaminated by graded levels of two Fusarium toxins on selected immunological and histological measurements in the spleen of gilts
    • Tiemann U., Brüssow K.P., Jonas L., Pöhland R., Schneider F., Dänicke S. Effects of diets with cereal grains contaminated by graded levels of two Fusarium toxins on selected immunological and histological measurements in the spleen of gilts. Journal of Animal Science 2006, 84:236-245.
    • (2006) Journal of Animal Science , vol.84 , pp. 236-245
    • Tiemann, U.1    Brüssow, K.P.2    Jonas, L.3    Pöhland, R.4    Schneider, F.5    Dänicke, S.6
  • 42
    • 45849116247 scopus 로고    scopus 로고
    • The effect of feeding a diet naturally contaminated with deoxynivalenol (DON) and zearalenone (ZON) on the spleen and liver of sow and fetus from day 35 to 70 of gestation
    • Tiemann U., Brüssow K.P., Dannenberger D., Jonas L., Pohland R., Jager K., Dänicke S., Hagemann E. The effect of feeding a diet naturally contaminated with deoxynivalenol (DON) and zearalenone (ZON) on the spleen and liver of sow and fetus from day 35 to 70 of gestation. Toxicology Letters 2008, 179:113-117.
    • (2008) Toxicology Letters , vol.179 , pp. 113-117
    • Tiemann, U.1    Brüssow, K.P.2    Dannenberger, D.3    Jonas, L.4    Pohland, R.5    Jager, K.6    Dänicke, S.7    Hagemann, E.8
  • 44
    • 0038447123 scopus 로고    scopus 로고
    • Receptors mediators, and mechanisms involved in bacterial sepsis and septic shock
    • Van Amersfoort E.S., Van Berkel T.J., Kuiper J. Receptors mediators, and mechanisms involved in bacterial sepsis and septic shock. Clinical Microbiology Reviews 2003, 16:379-414.
    • (2003) Clinical Microbiology Reviews , vol.16 , pp. 379-414
    • Van Amersfoort, E.S.1    Van Berkel, T.J.2    Kuiper, J.3
  • 45
    • 30044451139 scopus 로고    scopus 로고
    • In vitro and in vivo effects of deoxynivalenol (DNV) on regulators of cap dependent translation control in porcine endometrium
    • Wollenhaupt K., Dänicke S., Brüssow K.P., Tiemann U. In vitro and in vivo effects of deoxynivalenol (DNV) on regulators of cap dependent translation control in porcine endometrium. Reproductive Toxicology 2006, 21:60-73.
    • (2006) Reproductive Toxicology , vol.21 , pp. 60-73
    • Wollenhaupt, K.1    Dänicke, S.2    Brüssow, K.P.3    Tiemann, U.4


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