Intravenous inoculation of Staphylococcus aureus in pigs induces severe sepsis as indicated by increased hypercoagulability and hepatic dysfunction

FEMS Microbiology Letters

Volumn 309, Issue 2, 2010, Pages 208-216

  Leifsson, Páll S ^a   Iburg, Tine ^a   Jensen, Henrik E ^a   Agerholm, Jørgen S ^a   Kjelgaard Hansen, Mads ^a   Wiinberg, Bo ^a   Heegaard, Peter M H ^b   Astrup, Lærke B ^a   Olsson, Anna E ^a   Skov, Mette G ^a   Aalbæk, Bent ^a   Nielsen, Ole L ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b TECHNICAL UNIVERSITY OF DENMARK   (Denmark)

Author keywords

animal model; blood clotting; clinical chemistry; liver; severe sepsis; Staphylococcus aureus

Indexed keywords

C REACTIVE PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOPSY; BACTERIAL COUNT; BILIRUBIN BLOOD LEVEL; BLOOD CELL COUNT; BLOOD SAMPLING; BODY WEIGHT; CONTROLLED STUDY; DISEASE SEVERITY; FEMALE; HISTOPATHOLOGY; HYPERCOAGULABILITY; IRON BLOOD LEVEL; LIVER DYSFUNCTION; LIVER FAILURE; NEUTROPHILIA; NONHUMAN; PRIORITY JOURNAL; SEPSIS; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS INFECTION; SWINE; THROMBOCYTE COUNT; THROMBOELASTOGRAPHY; ANIMAL; BLOOD; BLOOD CLOTTING; DISEASE MODEL; HUMAN; LIVER DISEASE; METABOLISM; MICROBIOLOGY; PATHOGENICITY; PATHOLOGY; PHYSIOLOGY; RANDOMIZATION;

ANIMALIA; BACTERIA (MICROORGANISMS); STAPHYLOCOCCUS AUREUS; SUIDAE;

ANIMALS; BLOOD COAGULATION; C-REACTIVE PROTEIN; DISEASE MODELS, ANIMAL; FEMALE; HUMANS; INTERLEUKIN-6; LIVER DISEASES; PLATELET COUNT; RANDOM ALLOCATION; SEPSIS; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCUS AUREUS; SWINE;

EID: 77954696884     PISSN: 03781097     EISSN: 15746968     Source Type: Journal    
DOI: 10.1111/j.1574-6968.2010.02042.x     Document Type: Article

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