Secondary damage caused by CD11b+ microglia following diffuse axonal injury in rats

Journal of Trauma and Acute Care Surgery

Volumn 73, Issue 5, 2012, Pages 1168-1174

  Jia, Xianxian ^a   Cong, Bin ^a   Wang, Songjun ^a   Dong, Liru ^b   Ma, Chunling ^a   Li, Yingmin ^a  

^a HEBEI MEDICAL UNIVERSITY   (China)

^b HEBEI UNITED UNIVERSITY   (China)

Author keywords

A amyloid peptide precursor; CD11b; Diffuse axonal injury; Interleukin 6; Microglia

Indexed keywords

AMYLOID BETA PROTEIN; CD11B ANTIGEN; INTERLEUKIN 6;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CD11B+ CELL; CELL ACTIVATION; DIFFUSE AXONAL INJURY; HISTOPATHOLOGY; IMMUNOCYTOCHEMISTRY; MICROGLIA; MYELIN SHEATH; NICK END LABELING; NISSL SUBSTANCE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REACTION TIME; STAINING;

AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; ANTIGENS, CD11B; APOPTOSIS; DIFFUSE AXONAL INJURY; INTERLEUKIN-6; MALE; MICROGLIA; RATS; RATS, SPRAGUE-DAWLEY; TIME FACTORS;

EID: 84869845799     PISSN: 21630755     EISSN: 21630763     Source Type: Journal    
DOI: 10.1097/TA.0b013e318246eaf4     Document Type: Article

References (24)

1. Li XY, Li J, Feng DF, Gu L. Diffuse axonal injury induced by simultaneous moderate linear and angular head accelerations in rats. Neuroscience. 2010;169: 357-369.
2. Eastman CL,Verley DR, Fender JS, et al.Antiepileptic and antiepileptogenic performance of carisbamate after head injury in the rat: blind and randomized studies. J Pharmacol Exp Ther. 2011;336: 779-790.
3. Duncan CC, Summers AC, Perla EJ, Coburn KL, Mirsky AF. Evaluation of traumatic brain injury: brain potentials in diagnosis, function, and prognosis. Int J Psychophysiol. 2011;82: 24-40.
4. Kondo K, Maruishi M, Ueno H, et al. The pathophysiology of prospective memory failure after diffuse axonal injuryYlesion-symptom analysis using diffusion tensor imaging. BMC Neurosci. 2010;11:147.
5. Graham DI, Smith C, Reichard R, Leclercq PD, Gentleman SM. Trials and tribulations of using beta-amyloid precursor protein immunohistochemistry to evaluate traumatic brain injury in adults. Forensic Sci Int. 2004;146: 89-96.
6. Ljungqvist J, Nilsson D, Ljungberg M, et al. Longitudinal study of the diffusion tensor imaging properties of the corpus callosum in acute and chronic diffuse axonal injury. Brain Inj. 2011;25: 370-378.
7. Dohi K, Ohtaki H, Nakamachi T, et al. Gp91phox (NOX2) in classically activated microglia exacerbates traumatic brain injury. J Neuroinflammation. 2010;7:41.
8. Woiciechowsky C, Schöning B, Cobanov J, Lanksch WR, Volk HD, Döcke WD. Early IL-6 plasma concentrations correlate with severity of brain injury and pneumonia in brain-injured patients. J Trauma. 2002;52: 339-345.
9. Loane DJ, Byrnes KR. Role of microglia in neurotrauma. Neurotherapeutics. 2010;7: 366-377.
10. Johnson VE, StewartW, Smith DH. Traumatic brain injury and amyloid-A pathology: a link to Alzheimer's disease? Nat Rev Neurosci. 2010;11: 361-370.
11. Choucair-Jaafar N, Laporte V, Levy R, Poindron P, Lombard Y, Gies JP. Complement receptor 3 (CD11b/CD18) is implicated in the elimination of A-amyloid peptides. Fundam Clin Pharmacol. 2011;25: 115-122.
12. Thored P, Heldmann U, Gomes-Leal W, et al. Long-term accumulation of microglia with proneurogenic phenotype concomitant with persistent neurogenesis in adult subventricular zone after stroke. Glia. 2009;57: 835-849.
13. Matsumoto H, Kumon Y, Watanabe H, et al. Antibodies to CD11b, CD68, and lectin label neutrophils rather than microglia in traumatic and ischemic brain lesions. J Neurosci Res. 2007;85: 994-1009.
14. Venkatesan C, Chrzaszcz M, Choi N, Wainwright MS. Chronic upregulation of activated microglia immunoreactive for galectin-3/Mac-2 and nerve growth factor following diffuse axonal injury. J Neuroinflammation. 2010;7:32.
15. Schroeter M, Jander S, Huitinga I, Witte OW, Stoll G. Phagocytic response in photochemically induced infarction of rat cerebral cortex. The role of resident microglia. Stroke. 1997;28: 382-386.
16. Marmarou A, Foda MA, van den BrinkW, Campbell J, Kita H, Demetriadou K. A new model of diffuse brain injury in rats. Part I: pathophysiology and biomechanics. J Neurosurg. 1994;80: 291-300.
17. Foda MA, Marmarou A. A new model of diffuse brain injury in rats.Part II: morphological characterization. J Neurosurg. 1994;80: 301-313.
18. Hayashi T, Ago K, Ago M, Ogata M. Two patterns of beta-amyloid precursor protein (APP) immunoreactivity in cases of blunt head injury. Leg Med (Tokyo). 2009;11(Suppl 1):S171YS173.
19. Lucin KM, Wyss-Coray T. Immune activation in brain aging and neurodegeneration: too much or too little? Neuron. 2009;64: 110-122.
20. Aarli JA. Role of cytokines in neurological disorders. Curr Med Chem. 2003;10: 1931-1937.
21. Mima T, Nishimoto N. Clinical value of blocking IL-6 receptor. Curr Opin Rheumatol. 2009;21: 224-230.
22. Keightley M, Green S, Reed N, Agnihotri S, Wilkinson A, Lobaugh N. An investigation of the effects of sports-related concussion in youth using functional magnetic resonance imaging and the head impact telemetry system. J Vis Exp. 2011;(47):pii: 2226.
23. Yanagawa Y, Imamura T, Iwamoto S. A case of cerebral amyloid angiopathy mimicking diffuse axonal injury. Am J Emerg Med. 2010;28: 646.e1Ye3.
24. Smith EE, Greenberg SM. Beta-amyloid, blood vessels, and brain function. Stroke. 2009;40: 2601-2606.