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Volumn 3, Issue 4, 2012, Pages 482-490

Hyperglycemia Accentuates Persistent "Functional Uncoupling" of Cerebral Microvascular Nitric Oxide and Superoxide Following Focal Ischemia/Reperfusion in Rats

Author keywords

Cerebral blood flow; Cerebral infarction; Hyperglycemia; Nitric oxide; Superoxide anion

Indexed keywords

3 NITROTYROSINE; FLUORESCENT DYE; NITRIC OXIDE; SUPEROXIDE;

EID: 84869797378     PISSN: 18684483     EISSN: 1868601X     Source Type: Journal    
DOI: 10.1007/s12975-012-0210-9     Document Type: Article
Times cited : (22)

References (45)
  • 7
    • 3242657072 scopus 로고    scopus 로고
    • How important is hyperglycemia during acute brain infarction?
    • Bruno A, Williams LS, Kent TA. How important is hyperglycemia during acute brain infarction? Neurologist. 2004; 10(4): 195-200.
    • (2004) Neurologist , vol.10 , Issue.4 , pp. 195-200
    • Bruno, A.1    Williams, L.S.2    Kent, T.A.3
  • 8
    • 80054994277 scopus 로고    scopus 로고
    • Inhibition of protein kinase Cbeta reverses increased blood-brain barrier permeability during hyperglycemic stroke and prevents edema formation in vivo
    • Cipolla MJ, Huang Q, Sweet JG. Inhibition of protein kinase Cbeta reverses increased blood-brain barrier permeability during hyperglycemic stroke and prevents edema formation in vivo. Stroke J cereb circ. 2011; 42(11): 3252-7.
    • (2011) Stroke J Cereb Circ , vol.42 , Issue.11 , pp. 3252-3257
    • Cipolla, M.J.1    Huang, Q.2    Sweet, J.G.3
  • 9
    • 80052296902 scopus 로고    scopus 로고
    • Neurovascular injury in acute hyperglycemia and diabetes: a comparative analysis in experimental stroke
    • Elgebaly MM, Ogbi S, Li W, Mezzetti EM, Prakash R, Johnson MH, et al. Neurovascular injury in acute hyperglycemia and diabetes: a comparative analysis in experimental stroke. Transl stroke res. 2011; 2(3): 391-8.
    • (2011) Transl Stroke Res , vol.2 , Issue.3 , pp. 391-398
    • Elgebaly, M.M.1    Ogbi, S.2    Li, W.3    Mezzetti, E.M.4    Prakash, R.5    Johnson, M.H.6
  • 10
    • 36649002215 scopus 로고    scopus 로고
    • Increased hemorrhagic transformation and altered infarct size and localization after experimental stroke in a rat model type 2 diabetes
    • Ergul A, Elgebaly MM, Middlemore ML, Li W, Elewa H, Switzer JA, et al. Increased hemorrhagic transformation and altered infarct size and localization after experimental stroke in a rat model type 2 diabetes. BMC Neurol. 2007; 7: 33.
    • (2007) BMC Neurol , vol.7 , pp. 33
    • Ergul, A.1    Elgebaly, M.M.2    Middlemore, M.L.3    Li, W.4    Elewa, H.5    Switzer, J.A.6
  • 11
    • 67349179497 scopus 로고    scopus 로고
    • Hyperglycemia, diabetes and stroke: focus on the cerebrovasculature
    • Ergul A, Li W, Elgebaly MM, Bruno A, Fagan SC. Hyperglycemia, diabetes and stroke: focus on the cerebrovasculature. Vasc Pharmacol. 2009; 51(1): 44-9.
    • (2009) Vasc Pharmacol , vol.51 , Issue.1 , pp. 44-49
    • Ergul, A.1    Li, W.2    Elgebaly, M.M.3    Bruno, A.4    Fagan, S.C.5
  • 13
    • 57749177096 scopus 로고    scopus 로고
    • Endothelial dysfunction and diabetes: roles of hyperglycemia, impaired insulin signaling and obesity
    • Bakker W, Eringa EC, Sipkema P, van Hinsbergh VW. Endothelial dysfunction and diabetes: roles of hyperglycemia, impaired insulin signaling and obesity. Cell Tissue Res. 2009; 335(1): 165-89.
    • (2009) Cell Tissue Res , vol.335 , Issue.1 , pp. 165-189
    • Bakker, W.1    Eringa, E.C.2    Sipkema, P.3    van Hinsbergh, V.W.4
  • 15
    • 77955260310 scopus 로고    scopus 로고
    • Inhibition of endothelin-1 receptors improves impaired nitric oxide synthase-dependent dilation of cerebral arterioles in type-1 diabetic rats
    • Arrick DM, Mayhan WG. Inhibition of endothelin-1 receptors improves impaired nitric oxide synthase-dependent dilation of cerebral arterioles in type-1 diabetic rats. Microcirculation (New York, NY: 1994). 2010; 17(6): 439-46.
    • (2010) Microcirculation (New York, NY: 1994) , vol.17 , Issue.6 , pp. 439-446
    • Arrick, D.M.1    Mayhan, W.G.2
  • 16
    • 22644438381 scopus 로고    scopus 로고
    • Increased plasma markers of inflammation and endothelial dysfunction and their association with microvascular complications in type 1 diabetic patients without clinically manifest macroangiopathy
    • Targher G, Bertolini L, Zoppini G, Zenari L, Falezza G. Increased plasma markers of inflammation and endothelial dysfunction and their association with microvascular complications in type 1 diabetic patients without clinically manifest macroangiopathy. Diabet Med J British Diabet Assoc. 2005; 22(8): 999-1004.
    • (2005) Diabet Med J British Diabet Assoc , vol.22 , Issue.8 , pp. 999-1004
    • Targher, G.1    Bertolini, L.2    Zoppini, G.3    Zenari, L.4    Falezza, G.5
  • 17
    • 82955198542 scopus 로고    scopus 로고
    • Nitric oxide: a pleiotropic signal in the nervous system
    • Benarroch EE. Nitric oxide: a pleiotropic signal in the nervous system. Neurology. 2011; 77(16): 1568-76.
    • (2011) Neurology , vol.77 , Issue.16 , pp. 1568-1576
    • Benarroch, E.E.1
  • 18
    • 80053567234 scopus 로고    scopus 로고
    • Superoxide modulates myogenic contractions of mouse afferent arterioles
    • Lai EY, Wellstein A, Welch WJ, Wilcox CS. Superoxide modulates myogenic contractions of mouse afferent arterioles. Hypertension. 2011; 58(4): 650-6.
    • (2011) Hypertension , vol.58 , Issue.4 , pp. 650-656
    • Lai, E.Y.1    Wellstein, A.2    Welch, W.J.3    Wilcox, C.S.4
  • 19
    • 79957935756 scopus 로고    scopus 로고
    • NADPH oxidase-derived reactive oxygen species: involvement in vascular physiology and pathology
    • Manea A. NADPH oxidase-derived reactive oxygen species: involvement in vascular physiology and pathology. Cell Tissue Res. 2010; 342(3): 325-39.
    • (2010) Cell Tissue Res , vol.342 , Issue.3 , pp. 325-339
    • Manea, A.1
  • 20
    • 84862283957 scopus 로고    scopus 로고
    • Non-pharmacological therapy for atrial fibrillation: managing the left atrial appendage
    • Luis SA, Roper D, Incani A, Poon K, Haqqani H, Walters DL. Non-pharmacological therapy for atrial fibrillation: managing the left atrial appendage. Cardiol Res Pract. 2012; 2012: 304626.
    • (2012) Cardiol Res Pract , vol.2012 , pp. 304626
    • Luis, S.A.1    Roper, D.2    Incani, A.3    Poon, K.4    Haqqani, H.5    Walters, D.L.6
  • 21
    • 33751525147 scopus 로고    scopus 로고
    • Janus-faced role of endothelial NO synthase in vascular disease: uncoupling of oxygen reduction from NO synthesis and its pharmacological reversal
    • Förstermann U. Janus-faced role of endothelial NO synthase in vascular disease: uncoupling of oxygen reduction from NO synthesis and its pharmacological reversal. Biol Chem. 2006; 387(12): 1521-33.
    • (2006) Biol Chem , vol.387 , Issue.12 , pp. 1521-1533
    • Förstermann, U.1
  • 22
    • 84857835223 scopus 로고    scopus 로고
    • Inhalation of nitric oxide prevents ischemic brain damage in experimental stroke by selective dilatation of collateral arterioles
    • Terpolilli NA, Kim SW, Thal SC, Kataoka H, Zeisig V, Nitzsche B et al. Inhalation of nitric oxide prevents ischemic brain damage in experimental stroke by selective dilatation of collateral arterioles. Circ Res. 2011; 110: 727-738.
    • (2011) Circ Res. , vol.110 , pp. 727-738
    • Terpolilli, N.A.1    Kim, S.W.2    Thal, S.C.3    Kataoka, H.4    Zeisig, V.5    Nitzsche, B.6
  • 24
    • 0032475865 scopus 로고    scopus 로고
    • Superoxide generation from endothelial nitric-oxide synthase. A Ca2+/calmodulin-dependent and tetrahydrobiopterin regulatory process
    • Xia Y, Tsai AL, Berka V, Zweier JL. Superoxide generation from endothelial nitric-oxide synthase. A Ca2+/calmodulin-dependent and tetrahydrobiopterin regulatory process. J Biol Chem. 1998; 273(40): 25804-8.
    • (1998) J Biol Chem , vol.273 , Issue.40 , pp. 25804-25808
    • Xia, Y.1    Tsai, A.L.2    Berka, V.3    Zweier, J.L.4
  • 25
    • 57049119708 scopus 로고    scopus 로고
    • Perivascular nitric oxide and superoxide in neonatal cerebral hypoxia-ischemia
    • Fabian RH, Perez-Polo JR, Kent TA. Perivascular nitric oxide and superoxide in neonatal cerebral hypoxia-ischemia. Am J Physiol Heart Circ Physiol. 2008; 295(4): H1809-14.
    • (2008) Am J Physiol Heart Circ Physiol , vol.295 , Issue.4
    • Fabian, R.H.1    Perez-Polo, J.R.2    Kent, T.A.3
  • 26
    • 0034705774 scopus 로고    scopus 로고
    • Directed sampling for electrolyte analysis and water content of micro-punch samples shows large differences between normal and ischemic rat brain cortex
    • Hu W, Kharlamov A, Wang Y, Perez-Trepichio AD, Jones SC. Directed sampling for electrolyte analysis and water content of micro-punch samples shows large differences between normal and ischemic rat brain cortex. Brain Res. 2000; 868(2): 370-5.
    • (2000) Brain Res , vol.868 , Issue.2 , pp. 370-375
    • Hu, W.1    Kharlamov, A.2    Wang, Y.3    Perez-Trepichio, A.D.4    Jones, S.C.5
  • 27
    • 0027289075 scopus 로고
    • The evolution of acute stroke recorded by multimodal magnetic resonance imaging
    • Quast MJ, Huang NC, Hillman GR, Kent TA. The evolution of acute stroke recorded by multimodal magnetic resonance imaging. Magn Reson Imag. 1993; 11(4): 465-71.
    • (1993) Magn Reson Imag , vol.11 , Issue.4 , pp. 465-471
    • Quast, M.J.1    Huang, N.C.2    Hillman, G.R.3    Kent, T.A.4
  • 28
    • 33846882646 scopus 로고    scopus 로고
    • Brain oedema in focal ischaemia: molecular pathophysiology and theoretical implications
    • Simard JM, Kent TA, Chen M, Tarasov KV, Gerzanich V. Brain oedema in focal ischaemia: molecular pathophysiology and theoretical implications. Lancet Neurol. 2007; 6(3): 258-68.
    • (2007) Lancet Neurol , vol.6 , Issue.3 , pp. 258-268
    • Simard, J.M.1    Kent, T.A.2    Chen, M.3    Tarasov, K.V.4    Gerzanich, V.5
  • 29
    • 0024494427 scopus 로고
    • Reversible middle cerebral artery occlusion without craniectomy in rats
    • Longa EZ, Weinstein PR, Carlson S, Cummins R. Reversible middle cerebral artery occlusion without craniectomy in rats. Stroke J cereb circ. 1989; 20(1): 84-91.
    • (1989) Stroke J Cereb Circ , vol.20 , Issue.1 , pp. 84-91
    • Longa, E.Z.1    Weinstein, P.R.2    Carlson, S.3    Cummins, R.4
  • 30
    • 0038672174 scopus 로고    scopus 로고
    • Mislocalization of eNOS and upregulation of cerebral vascular Ca2+ channel activity in angiotensin-hypertension
    • Gerzanich V, Ivanova S, Zhou H, Simard JM. Mislocalization of eNOS and upregulation of cerebral vascular Ca2+ channel activity in angiotensin-hypertension. Hypertension. 2003; 41: 1124-30.
    • (2003) Hypertension , vol.41 , pp. 1124-1130
    • Gerzanich, V.1    Ivanova, S.2    Zhou, H.3    Simard, J.M.4
  • 32
    • 77950515980 scopus 로고    scopus 로고
    • Hydroethidine- and MitoSOX-derived red fluorescence is not a reliable indicator of intracellular superoxide formation: another inconvenient truth
    • Zielonka J, Kalyanaraman B. Hydroethidine- and MitoSOX-derived red fluorescence is not a reliable indicator of intracellular superoxide formation: another inconvenient truth. Free Radic Biol Med. 2010; 48(8): 983-1001.
    • (2010) Free Radic Biol Med , vol.48 , Issue.8 , pp. 983-1001
    • Zielonka, J.1    Kalyanaraman, B.2
  • 34
    • 0032054944 scopus 로고    scopus 로고
    • The statistics of synergism
    • Slinker BK. The statistics of synergism. J Mol Cell Cardiol. 1998; 30(4): 723-31.
    • (1998) J Mol Cell Cardiol , vol.30 , Issue.4 , pp. 723-731
    • Slinker, B.K.1
  • 35
    • 84863266319 scopus 로고    scopus 로고
    • Exacerbation of endothelial dysfunction during the progression of diabetes: role of oxidative stress
    • Huang A, Yang YM, Feher A, Bagi Z, Kaley G, Sun D. Exacerbation of endothelial dysfunction during the progression of diabetes: role of oxidative stress. Am J Physiol Regul Integr Comp Physiol. 2012; 302(6): R674-81.
    • (2012) Am J Physiol Regul Integr Comp Physiol , vol.302 , Issue.6
    • Huang, A.1    Yang, Y.M.2    Feher, A.3    Bagi, Z.4    Kaley, G.5    Sun, D.6
  • 36
    • 4644265193 scopus 로고    scopus 로고
    • Acetylcholine-induced relaxation of rabbit basilar artery in vitro is rapidly reduced by reactive oxygen species in acute hyperglycemia: role of NADPH oxidase
    • Sercombe R, Vicaut E, Oudart N, Sercombe C, Girard P. Acetylcholine-induced relaxation of rabbit basilar artery in vitro is rapidly reduced by reactive oxygen species in acute hyperglycemia: role of NADPH oxidase. J Cardiovasc Pharmacol. 2004; 44(4): 507-16.
    • (2004) J Cardiovasc Pharmacol , vol.44 , Issue.4 , pp. 507-516
    • Sercombe, R.1    Vicaut, E.2    Oudart, N.3    Sercombe, C.4    Girard, P.5
  • 37
    • 79960014508 scopus 로고    scopus 로고
    • Nitric oxide, a Janus-faced therapeutic target for diabetic microangiopathy-friend or foe?
    • Yamagishi S, Matsui T. Nitric oxide, a Janus-faced therapeutic target for diabetic microangiopathy-friend or foe? Pharmacol Res Off J Italian Pharmacol Soc. 2011; 64(3): 187-94.
    • (2011) Pharmacol Res Off J Italian Pharmacol Soc , vol.64 , Issue.3 , pp. 187-194
    • Yamagishi, S.1    Matsui, T.2
  • 39
    • 84855362074 scopus 로고    scopus 로고
    • Hyperglycemia promotes tissue plasminogen activator-induced hemorrhage by increasing superoxide production
    • Won SJ, Tang XN, Suh SW, Yenari MA, Swanson RA. Hyperglycemia promotes tissue plasminogen activator-induced hemorrhage by increasing superoxide production. Ann Neurol. 2011; 70(4): 583-90.
    • (2011) Ann Neurol , vol.70 , Issue.4 , pp. 583-590
    • Won, S.J.1    Tang, X.N.2    Suh, S.W.3    Yenari, M.A.4    Swanson, R.A.5
  • 40
    • 0028939857 scopus 로고
    • Nitric oxide synthase inhibitor NG-nitro-l-arginine methyl ester decreases ischemic damage in reversible focal cerebral ischemia in hyperglycemic rats
    • Quast MJ, Wei J, Huang NC. Nitric oxide synthase inhibitor NG-nitro-l-arginine methyl ester decreases ischemic damage in reversible focal cerebral ischemia in hyperglycemic rats. Brain Res. 1995; 677(2): 204-12.
    • (1995) Brain Res , vol.677 , Issue.2 , pp. 204-212
    • Quast, M.J.1    Wei, J.2    Huang, N.C.3
  • 41
    • 80051549032 scopus 로고    scopus 로고
    • Synthesis and recycling of tetrahydrobiopterin in endothelial function and vascular disease
    • Crabtree MJ, Channon KM. Synthesis and recycling of tetrahydrobiopterin in endothelial function and vascular disease. Nitr Oxide Biol Chem/Off J Nitr Oxide Soc. 2011; 25(2): 81-8.
    • (2011) Nitr Oxide Biol Chem/Off J Nitr Oxide Soc , vol.25 , Issue.2 , pp. 81-88
    • Crabtree, M.J.1    Channon, K.M.2
  • 43
    • 65949123566 scopus 로고    scopus 로고
    • Association of plasma asymmetrical dimethylarginine (ADMA) with elevated vascular superoxide production and endothelial nitric oxide synthase uncoupling: implications for endothelial function in human atherosclerosis
    • Antoniades C, Shirodaria C, Leeson P, Antonopoulos A, Warrick N, Van-Assche T, et al. Association of plasma asymmetrical dimethylarginine (ADMA) with elevated vascular superoxide production and endothelial nitric oxide synthase uncoupling: implications for endothelial function in human atherosclerosis. Eur Hear J. 2009; 30(9): 1142-50.
    • (2009) Eur Hear J , vol.30 , Issue.9 , pp. 1142-1150
    • Antoniades, C.1    Shirodaria, C.2    Leeson, P.3    Antonopoulos, A.4    Warrick, N.5    Van-Assche, T.6
  • 44
    • 0030988138 scopus 로고    scopus 로고
    • Nitric oxide synthase in models of focal ischemia
    • Samdani AF, Dawson TM, Dawson VL. Nitric oxide synthase in models of focal ischemia. Stroke J cereb circ. 1997; 28(6): 1283-8.
    • (1997) Stroke J Cereb Circ , vol.28 , Issue.6 , pp. 1283-1288
    • Samdani, A.F.1    Dawson, T.M.2    Dawson, V.L.3
  • 45
    • 84555208247 scopus 로고    scopus 로고
    • Effects of tetrahydrobiopterin on cerebral infarction after transient focal ischemia in rats
    • Tang LL, Zheng JS. Effects of tetrahydrobiopterin on cerebral infarction after transient focal ischemia in rats. Neurol Res. 2011; 33(10): 1064-7.
    • (2011) Neurol Res. , vol.33 , Issue.10 , pp. 1064-1067
    • Tang, L.L.1    Zheng, J.S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.