Rhein protects against obesity and related metabolic disorders through liver X receptor-mediated uncoupling protein 1 upregulation in brown adipose tissue

International Journal of Biological Sciences

Volumn 8, Issue 10, 2012, Pages 1375-1384

  Sheng, Xiaoyan ^a   Zhu, Xuehua ^b   Zhang, Yuebo ^a   Cui, Guoliang ^a   Peng, Linling ^c   Lu, Xiong ^d   Zang, Ying Qin ^a  

^a Chinese Academy of Sciences   (China)

^b TONGJI UNIVERSITY   (China)

^c SHANGHAI SECOND MEDICAL UNIVERSITY   (China)

^d SHANGHAI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

Author keywords

Antagonist; Diet induced obesity; LXR; Rhein; UCP1

Indexed keywords

ANTHRAQUINONE DERIVATIVE; ANTIOBESITY AGENT; ION CHANNEL; LIVER X RECEPTOR; MITOCHONDRIAL PROTEIN; MITOCHONDRIAL UNCOUPLING PROTEIN; ORPHAN NUCLEAR RECEPTOR; RHEIN;

ADIPOCYTE; ANIMAL; ARTICLE; BROWN ADIPOSE TISSUE; C57BL MOUSE; CELL STRAIN 3T3; CHEMISTRY; DRUG ANTAGONISM; DRUG EFFECT; GENE EXPRESSION; GENE INACTIVATION; GENETICS; LIPID DIET; METABOLIC DISORDER; METABOLISM; MOLECULAR GENETICS; MOUSE; MOUSE MUTANT; NUCLEOTIDE SEQUENCE; OBESITY; ORAL DRUG ADMINISTRATION; RHEUM; SURFACE PLASMON RESONANCE;

ADIPOCYTES; ADIPOSE TISSUE, BROWN; ADMINISTRATION, ORAL; ANIMALS; ANTHRAQUINONES; ANTI-OBESITY AGENTS; DIET, HIGH-FAT; GENE EXPRESSION; GENE KNOCKOUT TECHNIQUES; ION CHANNELS; METABOLIC DISEASES; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MITOCHONDRIAL PROTEINS; MOLECULAR SEQUENCE DATA; NIH 3T3 CELLS; OBESITY; ORPHAN NUCLEAR RECEPTORS; RHEUM; SURFACE PLASMON RESONANCE;

MUS; RHEUM PALMATUM;

EID: 84869785022     PISSN: 14492288     EISSN: None     Source Type: Journal    
DOI: 10.7150/ijbs.4575     Document Type: Article

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