On the origin of the liver

Journal of Clinical Investigation

Volumn 121, Issue 12, 2011, Pages 4630-4633

  Friedman, Joshua R ^a   Kaestner, Klaus H ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,4 DIHYDRO 2,4,6 TRIMETHYL 3,5 PYRIDINEDICARBOXYLIC ACID DIETHYL ESTER; ALPHA 1 ANTITRYPSIN; CARBON TETRACHLORIDE; PARVOVIRUS VECTOR; THYMIDINE; TRANSCRIPTION FACTOR SOX9;

BILE DUCT LIGATION; CELL DIFFERENTIATION; CELL LINEAGE; CELL METABOLISM; CELL POPULATION; CELL PROLIFERATION; CELL RENEWAL; CELL THERAPY; CHOLESTASIS; ENDODERM; HUMAN; IMMUNOHISTOCHEMISTRY; INTRAHEPATIC BILE DUCT; LIVER CELL; LIVER DEVELOPMENT; LIVER DISEASE; LIVER INJURY; LIVER PARENCHYMA; LIVER REGENERATION; LIVER RESECTION; NOTE; PRIORITY JOURNAL; RETROVIRUS INFECTION; STEM CELL;

ANIMALS; HEPATOCYTES; HOMEOSTASIS; LIVER; LIVER REGENERATION;

EID: 84055191103     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI59652     Document Type: Note

References (19)

1. Malato Y, et al. Fate tracing of mature hepatocytes in mouse liver homeostasis and regeneration. J Clin Invest. 2011;121(12):4850-4860.
2. Zorn AM. Liver development. In: Girard L, ed. Stem- Book. Cambridge, Massachusetts, USA: Harvard Stem Cell Institute; 2008.
3. Brues AM, Marble BB. An analysis of mitosis in liver restoration. J Exp Med. 1937;65(1):15-27.
4. Duncan AW, Dorrell C, Grompe M. Stem cells and liver regeneration. Gastroenterology. 2009;137(2):466-481.
5. Overturf K, al-Dhalimy M, Ou CN, Finegold M, Grompe M. Serial transplantation reveals the stem-cell-like regenerative potential of adult mouse hepatocytes. Am J Path. 1997;151(5):1273-1280. (Pubitemid 27479757)
6. Grisham JW. A morphologic study of deoxyribonucleic acid synthesis and cell proliferation in regenerating rat liver; autoradiography with thymidine- H3. Cancer Res. 1962;22:842-849.
7. Zajicek G, Oren R, Weinreb M Jr. The streaming liver. Liver. 1985;5(6):293-300. (Pubitemid 16162133)
8. Fletcher J, et al. The inhibitory role of stromal cell mesenchyme on human embryonic stem cell hepatocyte differentiation is overcome by Wnt3a treatment. Cloning Stem Cells. 2008; 10(3):331-339.
9. Kennedy S, Rettinger S, Flye MW, Ponder KP. Experiments in transgenic mice show that hepatocytes are the source for postnatal liver growth and do not stream. Hepatology. 1995;22(1):160-168.
10. Bralet MP, Branchereau S, Brechot C, Ferry N. Cell lineage study in the liver using retroviral mediated gene transfer. Evidence against the streaming of hepatocytes in normal liver. Am J Pathol. 1994;144(5):896-905. (Pubitemid 24160631)
11. Grisham JW. Grisham: reply. Am J Pathol. 1995; 146(3):773-776.
12. Suzuki A, et al. Flow cytometric isolation and clonal identification of self-renewing bipotent hepatic progenitor cells in adult mouse liver. Hepatology. 2008;48(6):1964-1978.
13. Wang X, Foster M, Al-Dhalimy M, Lagasse E, Finegold M, Grompe M. The origin and liver repopulating capacity of murine oval cells. Proc Natl Acad Sci U S A. 2003;100 suppl 1:11881-11888. (Pubitemid 37205899)
14. Shin S, et al. Foxl1-Cre-marked adult hepatic progenitors have clonogenic and bilineage differentiation potential. Genes Dev. 2011;25(11):1185-1192.
15. Schwartz RE, et al. Multipotent adult progenitor cells from bone marrow differentiate into functional hepatocyte-like cells. J Clin Invest. 2002;109(10):1291-1302. (Pubitemid 34546893)
16. Jiang Y, et al. Pluripotency of mesenchymal stem cells derived from adult marrow. Nature. 2002; 418(6893):41-49. (Pubitemid 34742565)
17. Furuyama K, et al. Continuous cell supply from a Sox9-expressing progenitor zone in adult liver, exocrine pancreas and intestine. Nat Genet. 2011; 43(1):34-41.
18. Antoniou A, et al. Intrahepatic bile ducts develop according to a new mode of tubulogenesis regulated by the transcription factor SOX9. Gastroenterology. 2009;136(7):2325-2333.
19. Seymour PA, et al. SOX9 is required for maintenance of the pancreatic progenitor cell pool. Proc Natl Acad Sci U S A. 2007;104(6):1865-1870. (Pubitemid 46239870)