Differentiation of putative hepatic stem cells derived from adult rats into mature hepatocytes in the presence of epidermal growth factor and hepatocyte growth factor

Differentiation

Volumn 71, Issue 4-5, 2003, Pages 281-290

  He, Z P ^a   Tan, W Q ^a   Tang, Y F ^a   Feng, M F ^a  

^a INSTITUTE OF ZOOLOGY   (China)

Author keywords

Differentiation; Epidermal growth factor; Hepatic stimulator substance; Hepatocyte growth factor; Mature hepatocytes; Oval cells; Small hepatocytes

Indexed keywords

ALBUMIN; ALPHA 1 ANTITRYPSIN; CYTOKERATIN 19; CYTOKERATIN 7; EPIDERMAL GROWTH FACTOR; MESSENGER RNA; OV 6 ANTIGEN; SCATTER FACTOR; TYROSINE AMINOTRANSFERASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL ASSAY; CELL DIFFERENTIATION; CELL FUNCTION; CELL ISOLATION; CELL MATURATION; CELL SECRETION; CELL SHAPE; CELL STRUCTURE; CELL TRANSPLANTATION; CELL TYPE; CELL ULTRASTRUCTURE; CONTROLLED STUDY; DENSITY GRADIENT CENTRIFUGATION; ENZYME ACTIVITY; LIVER CELL; MALE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN SECRETION; PROTEIN SYNTHESIS; RAT; STEM CELL; TISSUE ENGINEERING;

ANIMALIA;

EID: 0038010055     PISSN: 03014681     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1432-0436.2003.7104505.x     Document Type: Article

References (30)

1. Avital, I., Inderbitzin, D., Aoki, T., Tyan, D.B., Cohen, A.H., Ferraresso, C., Rozga, J., Arnaout, W.S. and Demetriou, A.A. (2001) Isolation, characterization, and transplantation of bone marrow-derived hepatocyte stem cells. Biochem Biophys Res Commun 288:156-164.
2. Block, G.D., Locker, J., Bowen, W.C., Petersen, B.E., Katyal, S., Strom, S.C., Riley, T., Howard, T.A. and Michalopoulos, G.K. (1996) Population expansion, clonal growth and specific differentiation patterns in primary cultures of hepatocytes induced by HGF/SF, EGF and TGF alpha in a chemically defined (HGM) medium. J Cell Biol 132:1133-1149.
3. Crosby, H.A., Kelly, D.A. and Strain, A.J. (2001) Human hepatic stem like cells isolated using c-kit or CD34 can differentiate into biliary epithelium. Gastroenterology 120:534-544.
4. Dumble, M.L., Croager, E.J., Yeoh, G.C. and Quail, E.A. (2002) Generation and characterization of p53 null transformed hepatic progenitor cells: oval cells give rise to hepatocellular carcinoma. Carcinogenesis 23:435-445.
5. Faris, R.A., Konkin, T. and Halpert, G. (2001) Liver stem cells: a potential source of hepatocytes for the treatment of human liver disease. Artif Organs 25:513-521.
6. Faris, R.A., Monfils, B.A., Dunsford, H.A. and Hixson, D.C. (1991) Antigenic relationship between oval cells and a subpopulation of hepatic foci, nodules, and carcinomas induced by the "resistant hepatocytes" model system. Cancer Res 51:1308-1317.
7. Fleig, W.E. and Hoss, G. (1989) Partial purification of rat hepatic stimulator substance and characterization of its action on hepatoma cells and normal hepatocytes. Hepatology 9:240-248.
8. Golding, M., Sarraf, C.E., Lalani, E.N., Anilkumar, T.V., Edwards, R.J., Nagy, P., Thorgeirsson, S.S. and Alison, M.R. (1995) Oval cell differentiation into hepatocytes in the acetylaminofluorene-treated regenerating rat liver. Hepatology 22:1243-1253.
9. He, Z.P., Tang, Y.F., Liu, Y.B. and Feng, M.F. (2003) Advances in studies on hepatic stem cells. Prog Nat Sci 13:166-172.
10. Hixson, D.C., Chapman, L., McBride, A., Faris, R. and Yang, L. (1997) Antigenic phenotypes common to rat oval cells, primary hepatocellular carcinomas and developing bile ducts. Carcinogenesis 18:1169-1175.
11. Isfort, R.J., Cody, D.B., Stuard, S.B., Randall, C.J., Miller, C., Ridder, G.M., Doersen, C.J., Richards, W.G., Yoder, B.K., Wilkinson, J.E. and Woychik, R.P. (1997) The combination of epidermal growth factor and transforming growth factor-beta induces novel phenotypic changes in mouse liver stem cell lines. J Cell Sci 10:3117-3129.
12. LaBrecque, D.R. (1991) Hepatic stimulator substance: discovery, characteristics and mechanism of action. Dig Dis Sci 36:669-673.
13. Lazaro, C.A., Rhim, J.A., Yamada, Y. and Fausto, N. (1998) Generation of hepatocytes from oval precursors in culture. Cancer Res 58:5514-5522.
14. Liu, X.J., An, W., Lei, T.G., Rong, Y. and Du, G.G. (1998) Regulator effect of hepatic stimulator substance on the proliferation of human hepatoma cell. Acta Physiol Sin 50:543-550.
15. Monga, S.P., Tang, Y., Candotti, F., Rashid, A., Wildner, O., Mishra, B., Iqbal, S. and Mishra, L. (2001) Expansion of hepatic and hematopoietic stem cells utilizing mouse embryonic liver explants. Cell Transplant 10:81-89.
16. Pack, R., Heck, R., Dienes, H.P., Oesch, F. and Steinberg, P. (1993) Isolation, biochemical characterization, long-term culture, and phenotype modulation of oval cells form carcinogen-fed rats. Exp Cell Res 204:198-209.
17. Petersen, B.E. (2001) Hepatic "stem cells" coming full circle. Blood Cell Mol Dis 27:590-600.
18. Petersen, B.E., Bowen, W.C., Patrene, K.D., Mars, W.M., Sullivan, A.K., Murase, N., Boggs, S.S., Greenberger, J.S. and Goff, J.P. (1999) Bone marrow as a potential source of hepatic oval cells. Science 284:1168-1170.
19. Ruck, P., Xiao, J.C. and Kaiserling, E. (1996) Small epithelial cells and histogenesis of hepato-blastoma: electron microscopic, immunoelectron microscopic, and immunohistochemical findings. Am J Pathol 148:321-329.
20. Schmidt, C., Bladt, F., Goedecke, S., Brinkmann, V., Zschiesche, W., Sharpe, M., Gherardi, E. and Bichmeir, C. (1995) Scatter factor/hepatocyte growth factor is essential for live development. Nature 373:699-702.
21. Sell, S. (1990) Is there a liver stem cell? Cancer Res 50:3811-3815.
22. Sell, S. and Pierce, G.B. (1994) Maturation arrest of stem cell differentiation is a common pathway for the cellular origin of teratocarcinomas and epithelial cancers. Lab Invest 70:6-21.
23. Strain, A.J. and Neuberger, J.M. (2002) A bioartificial liver-state of the art. Science 295:1005-1009.
24. Strain, A.J., Wallace, L., Joplin, R., Daikuhara, Y., Ishii, T., Kelly, D.A. and Neuberger, J.M. (1995) Characterization of biliary epithelial cells isolated from needle biopsies of human liver in the presence of hepatocyte growth factor. Am J Pathol 146:537-545.
25. Suzuki, A., Zheng, Y.W., Kaneko, S., Onodera, M., Fukao, K., Nakauchi, H. and Taniguchi, H. (2002) Clonal identification and characterization of self-renewing pluripotent stem cells in the developing liver. J Cell Biol 156:173-184.
26. Tatematsu, M., Kaku, T., Medline, A. and Farber, E. (1985) Intestinal metaplasia as a common option of oval cells in relation to cholangiofibrosis in liver of rats exposed to 2-acetylaminofluorene. Lab Invest 52:354-362.
27. Theise, N.D., Nimmakayalu, M., Gardner, R., Illei, P.B., Morgan, G., Teperman, L., Henegariu, O. and Krause, D.S. (2000) Liver from bone marrow in humans. Hepatology 32:11-16.
28. Thorgeirsson, S.S., Evarts, R.P., Bisgaard, H.C., Fujio, K. and Hu, Z. (1993) Hepatic stem cell compartment: activation and lineage commitment. Proc Soc Exp Bio Med 204:253-260.
29. Yang, L., Li, S., Hatch, H., Ahrens, K., Cornel, J.G., Petersen, B.E. and Peck, A.B. (2002) In vitro trans-differentiation of adult hepatic stem cells into pancreatic endocrine hormone-producing cells. Proc Natl Acad Sci U S A 99:8078-8083.
30. Zhou, Z., Tan, R., Su, S. and Zhou, C. (1992) Effects of human HSS on hepatocyte and hepatoma cell proliferation and D-GAL induced acute liver failure. Chin Med Sci J 7:197-200.