-
1
-
-
5644285309
-
Human tribbles, a protein family controlling mitogen-activated protein kinase cascades
-
Kiss-Toth E, Bagstaff SM, Sung HY, Jozsa V, Dempsey C, et al. (2004) Human tribbles, a protein family controlling mitogen-activated protein kinase cascades. J Biol Chem 279: 42703-42708.
-
(2004)
J Biol Chem
, vol.279
, pp. 42703-42708
-
-
Kiss-Toth, E.1
Bagstaff, S.M.2
Sung, H.Y.3
Jozsa, V.4
Dempsey, C.5
-
2
-
-
80054027591
-
TRB3 interacts with SMAD3 promoting tumor cell migration and invasion
-
Hua F, Mu R, Liu J, Xue J, Wang Z, et al. (2011) TRB3 interacts with SMAD3 promoting tumor cell migration and invasion. J Cell Sci 124: 3235-3246.
-
(2011)
J Cell Sci
, vol.124
, pp. 3235-3246
-
-
Hua, F.1
Mu, R.2
Liu, J.3
Xue, J.4
Wang, Z.5
-
3
-
-
76349093390
-
Molecular basis for antagonism between PDGF and the TGFbeta family of signalling pathways by control of miR-24 expression
-
Chan MC, Hilyard AC, Wu C, Davis BN, Hill NS, et al. (2010) Molecular basis for antagonism between PDGF and the TGFbeta family of signalling pathways by control of miR-24 expression. EMBO J 29: 559-573.
-
(2010)
EMBO J
, vol.29
, pp. 559-573
-
-
Chan, M.C.1
Hilyard, A.C.2
Wu, C.3
Davis, B.N.4
Hill, N.S.5
-
4
-
-
48649103713
-
Multiple pathways are involved in the anoxia response of SKIP3 including HuR-regulated RNA stability, NF-kappaB and ATF4
-
Rzymski T, Paantjens A, Bod J, Harris AL, (2008) Multiple pathways are involved in the anoxia response of SKIP3 including HuR-regulated RNA stability, NF-kappaB and ATF4. Oncogene 27: 4532-4543.
-
(2008)
Oncogene
, vol.27
, pp. 4532-4543
-
-
Rzymski, T.1
Paantjens, A.2
Bod, J.3
Harris, A.L.4
-
5
-
-
0037697247
-
SINK is a p65-interacting negative regulator of NF-kappa B-dependent transcription
-
Wu M, Xu LG, Zhai ZH, Shu HB, (2003) SINK is a p65-interacting negative regulator of NF-kappa B-dependent transcription. Journal of Biological Chemistry 278: 27072-27079.
-
(2003)
Journal of Biological Chemistry
, vol.278
, pp. 27072-27079
-
-
Wu, M.1
Xu, L.G.2
Zhai, Z.H.3
Shu, H.B.4
-
6
-
-
40949162295
-
PI3K activates negative and positive signals to regulate TRB3 expression in hepatic cells
-
Ding JX, Kato S, Du KY, (2008) PI3K activates negative and positive signals to regulate TRB3 expression in hepatic cells. Experimental Cell Research 314: 1566-1574.
-
(2008)
Experimental Cell Research
, vol.314
, pp. 1566-1574
-
-
Ding, J.X.1
Kato, S.2
Du, K.Y.3
-
7
-
-
80052025916
-
Tribbles homolog 3 denotes a poor prognosis in breast cancer and is involved in hypoxia response
-
Wennemers M, Bussink J, Scheijen B, Nagtegaal ID, van Laarhoven HW, et al. (2011) Tribbles homolog 3 denotes a poor prognosis in breast cancer and is involved in hypoxia response. Breast Cancer Res 13: R82.
-
(2011)
Breast Cancer Res
, vol.13
-
-
Wennemers, M.1
Bussink, J.2
Scheijen, B.3
Nagtegaal, I.D.4
van Laarhoven, H.W.5
-
8
-
-
70449346285
-
Abnormal expression of TRIB3 in colorectal cancer: a novel marker for prognosis
-
Miyoshi N, Ishii H, Mimori K, Takatsuno Y, Kim H, et al. (2009) Abnormal expression of TRIB3 in colorectal cancer: a novel marker for prognosis. Br J Cancer 101: 1664-1670.
-
(2009)
Br J Cancer
, vol.101
, pp. 1664-1670
-
-
Miyoshi, N.1
Ishii, H.2
Mimori, K.3
Takatsuno, Y.4
Kim, H.5
-
9
-
-
80655124688
-
TRIB3 protein denotes a good prognosis in breast cancer patients and is associated with hypoxia sensitivity
-
Wennemers M, Bussink J, Grebenchtchikov N, Sweep FC, Span PN, (2011) TRIB3 protein denotes a good prognosis in breast cancer patients and is associated with hypoxia sensitivity. Radiother Oncol 101: 198-202.
-
(2011)
Radiother Oncol
, vol.101
, pp. 198-202
-
-
Wennemers, M.1
Bussink, J.2
Grebenchtchikov, N.3
Sweep, F.C.4
Span, P.N.5
-
10
-
-
80053990934
-
TRB3 overexpression due to endoplasmic reticulum stress inhibits AKT kinase activation of tongue squamous cell carcinoma
-
Zhang J, Wen HJ, Guo ZM, Zeng MS, Li MZ, et al. (2011) TRB3 overexpression due to endoplasmic reticulum stress inhibits AKT kinase activation of tongue squamous cell carcinoma. Oral Oncol 47: 934-939.
-
(2011)
Oral Oncol
, vol.47
, pp. 934-939
-
-
Zhang, J.1
Wen, H.J.2
Guo, Z.M.3
Zeng, M.S.4
Li, M.Z.5
-
11
-
-
76349108260
-
Anaphase-promoting complex/cyclosome-cdh1 mediates the ubiquitination and degradation of TRB3
-
Ohoka N, Sakai S, Onozaki K, Nakanishi M, Hayashi H, Anaphase-promoting complex/cyclosome-cdh1 mediates the ubiquitination and degradation of TRB3. Biochem Biophys Res Commun 392: 289-294.
-
Biochem Biophys Res Commun
, vol.392
, pp. 289-294
-
-
Ohoka, N.1
Sakai, S.2
Onozaki, K.3
Nakanishi, M.4
Hayashi, H.5
-
12
-
-
33645321647
-
MicroRNAs in cell proliferation, cell death, and tumorigenesis
-
Hwang HW, Mendell JT, (2006) MicroRNAs in cell proliferation, cell death, and tumorigenesis. Br J Cancer 94: 776-780.
-
(2006)
Br J Cancer
, vol.94
, pp. 776-780
-
-
Hwang, H.W.1
Mendell, J.T.2
-
13
-
-
11844278458
-
Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets
-
Lewis BP, Burge CB, Bartel DP, (2005) Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell 120: 15-20.
-
(2005)
Cell
, vol.120
, pp. 15-20
-
-
Lewis, B.P.1
Burge, C.B.2
Bartel, D.P.3
-
14
-
-
79959805164
-
miRWalk-database: prediction of possible miRNA binding sites by "walking" the genes of three genomes
-
Dweep H, Sticht C, Pandey P, Gretz N, (2011) miRWalk-database: prediction of possible miRNA binding sites by "walking" the genes of three genomes. J Biomed Inform 44: 839-847.
-
(2011)
J Biomed Inform
, vol.44
, pp. 839-847
-
-
Dweep, H.1
Sticht, C.2
Pandey, P.3
Gretz, N.4
-
15
-
-
33847234988
-
A microRNA signature of hypoxia
-
Kulshreshtha R, Ferracin M, Wojcik SE, Garzon R, Alder H, et al. (2007) A microRNA signature of hypoxia. Mol Cell Biol 27: 1859-1867.
-
(2007)
Mol Cell Biol
, vol.27
, pp. 1859-1867
-
-
Kulshreshtha, R.1
Ferracin, M.2
Wojcik, S.E.3
Garzon, R.4
Alder, H.5
-
16
-
-
79951782373
-
MicroRNA-24 regulates the processing of latent TGFbeta1 during cyclic mechanical stress in human trabecular meshwork cells through direct targeting of FURIN
-
Luna C, Li G, Qiu J, Epstein DL, Gonzalez P, (2011) MicroRNA-24 regulates the processing of latent TGFbeta1 during cyclic mechanical stress in human trabecular meshwork cells through direct targeting of FURIN. J Cell Physiol 226: 1407-1414.
-
(2011)
J Cell Physiol
, vol.226
, pp. 1407-1414
-
-
Luna, C.1
Li, G.2
Qiu, J.3
Epstein, D.L.4
Gonzalez, P.5
-
17
-
-
68949169031
-
MicroRNA-23b cluster microRNAs regulate transforming growth factor-beta/bone morphogenetic protein signaling and liver stem cell differentiation by targeting Smads
-
Rogler CE, Levoci L, Ader T, Massimi A, Tchaikovskaya T, et al. (2009) MicroRNA-23b cluster microRNAs regulate transforming growth factor-beta/bone morphogenetic protein signaling and liver stem cell differentiation by targeting Smads. Hepatology 50: 575-584.
-
(2009)
Hepatology
, vol.50
, pp. 575-584
-
-
Rogler, C.E.1
Levoci, L.2
Ader, T.3
Massimi, A.4
Tchaikovskaya, T.5
-
18
-
-
43349091055
-
Transforming growth factor-beta-regulated miR-24 promotes skeletal muscle differentiation
-
Sun Q, Zhang Y, Yang G, Chen X, Cao G, et al. (2008) Transforming growth factor-beta-regulated miR-24 promotes skeletal muscle differentiation. Nucleic Acids Res 36: 2690-2699.
-
(2008)
Nucleic Acids Res
, vol.36
, pp. 2690-2699
-
-
Sun, Q.1
Zhang, Y.2
Yang, G.3
Chen, X.4
Cao, G.5
-
19
-
-
74049111298
-
Increased MKK4 abundance with replicative senescence is linked to the joint reduction of multiple microRNAs
-
Marasa BS, Srikantan S, Masuda K, Abdelmohsen K, Kuwano Y, et al. (2009) Increased MKK4 abundance with replicative senescence is linked to the joint reduction of multiple microRNAs. Sci Signal 2: ra69.
-
(2009)
Sci Signal
, vol.2
-
-
Marasa, B.S.1
Srikantan, S.2
Masuda, K.3
Abdelmohsen, K.4
Kuwano, Y.5
-
20
-
-
46849122501
-
p16(INK4a) translation suppressed by miR-24
-
Lal A, Kim HH, Abdelmohsen K, Kuwano Y, Pullmann R Jr, et al. (2008) p16(INK4a) translation suppressed by miR-24. PLoS One 3: e1864.
-
(2008)
PLoS One
, vol.3
-
-
Lal, A.1
Kim, H.H.2
Abdelmohsen, K.3
Kuwano, Y.4
Pullmann Jr., R.5
-
21
-
-
77949495697
-
MiR-24 tumor suppressor activity is regulated independent of p53 and through a target site polymorphism
-
Mishra PJ, Song B, Wang Y, Humeniuk R, Banerjee D, et al. (2009) MiR-24 tumor suppressor activity is regulated independent of p53 and through a target site polymorphism. PLoS One 4: e8445.
-
(2009)
PLoS One
, vol.4
-
-
Mishra, P.J.1
Song, B.2
Wang, Y.3
Humeniuk, R.4
Banerjee, D.5
-
22
-
-
23844534811
-
Reporting recommendations for tumor marker prognostic studies (REMARK)
-
McShane LM, Altman DG, Sauerbrei W, Taube SE, Gion M, et al. (2005) Reporting recommendations for tumor marker prognostic studies (REMARK). J Natl Cancer Inst 97: 1180-1184.
-
(2005)
J Natl Cancer Inst
, vol.97
, pp. 1180-1184
-
-
McShane, L.M.1
Altman, D.G.2
Sauerbrei, W.3
Taube, S.E.4
Gion, M.5
-
24
-
-
39749116239
-
Hypoxia and regulation of messenger RNA translation
-
Koritzinsky M, Wouters BG, (2007) Hypoxia and regulation of messenger RNA translation. Methods Enzymol 435: 247-273.
-
(2007)
Methods Enzymol
, vol.435
, pp. 247-273
-
-
Koritzinsky, M.1
Wouters, B.G.2
-
25
-
-
84871146734
-
-
TargetScanHuman Whitehead Institute for Biomedical Research
-
http://www.targetscan.org/ (2012) TargetScanHuman Whitehead Institute for Biomedical Research.
-
(2012)
-
-
-
26
-
-
17144417669
-
TRB3, a novel ER stress-inducible gene, is induced via ATF4-CHOP pathway and is involved in cell death
-
Ohoka N, Yoshii S, Hattori T, Onozaki K, Hayashi H, (2005) TRB3, a novel ER stress-inducible gene, is induced via ATF4-CHOP pathway and is involved in cell death. Embo Journal 24: 1243-1255.
-
(2005)
Embo Journal
, vol.24
, pp. 1243-1255
-
-
Ohoka, N.1
Yoshii, S.2
Hattori, T.3
Onozaki, K.4
Hayashi, H.5
-
27
-
-
34548647535
-
TRB3 protects cells against the growth inhibitory and cytotoxic effect of ATF4
-
Ord D, Meerits K, Ord T, (2007) TRB3 protects cells against the growth inhibitory and cytotoxic effect of ATF4. Experimental Cell Research 313: 3556-3567.
-
(2007)
Experimental Cell Research
, vol.313
, pp. 3556-3567
-
-
Ord, D.1
Meerits, K.2
Ord, T.3
-
28
-
-
66449115318
-
Cannabinoid action induces autophagy-mediated cell death through stimulation of ER stress in human glioma cells
-
Salazar M, Carracedo A, Salanueva IJ, Hernandez-Tiedra S, Lorente M, et al. (2009) Cannabinoid action induces autophagy-mediated cell death through stimulation of ER stress in human glioma cells. Journal of Clinical Investigation 119: 1359-1372.
-
(2009)
Journal of Clinical Investigation
, vol.119
, pp. 1359-1372
-
-
Salazar, M.1
Carracedo, A.2
Salanueva, I.J.3
Hernandez-Tiedra, S.4
Lorente, M.5
-
29
-
-
0036896722
-
Pimonidazole binding and tumor vascularity predict for treatment outcome in head and neck cancer
-
Kaanders JH, Wijffels KI, Marres HA, Ljungkvist AS, Pop LA, et al. (2002) Pimonidazole binding and tumor vascularity predict for treatment outcome in head and neck cancer. Cancer Res 62: 7066-7074.
-
(2002)
Cancer Res
, vol.62
, pp. 7066-7074
-
-
Kaanders, J.H.1
Wijffels, K.I.2
Marres, H.A.3
Ljungkvist, A.S.4
Pop, L.A.5
-
30
-
-
43649107785
-
Molecular aspects of tumour hypoxia
-
Rademakers SE, Span PN, Kaanders JH, Sweep FC, van der Kogel AJ, et al. (2008) Molecular aspects of tumour hypoxia. Mol Oncol 2: 41-53.
-
(2008)
Mol Oncol
, vol.2
, pp. 41-53
-
-
Rademakers, S.E.1
Span, P.N.2
Kaanders, J.H.3
Sweep, F.C.4
van der Kogel, A.J.5
-
31
-
-
74949118681
-
The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5
-
Rouschop KM, van den Beucken T, Dubois L, Niessen H, Bussink J, et al. (2010) The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5. J Clin Invest 120: 127-141.
-
(2010)
J Clin Invest
, vol.120
, pp. 127-141
-
-
Rouschop, K.M.1
van den Beucken, T.2
Dubois, L.3
Niessen, H.4
Bussink, J.5
-
32
-
-
77956475436
-
Cooperative and individualistic functions of the microRNAs in the miR-23a~27a~24-2 cluster and its implication in human diseases
-
Chhabra R, Dubey R, Saini N, (2010) Cooperative and individualistic functions of the microRNAs in the miR-23a~27a~24-2 cluster and its implication in human diseases. Mol Cancer 9: 232.
-
(2010)
Mol Cancer
, vol.9
, pp. 232
-
-
Chhabra, R.1
Dubey, R.2
Saini, N.3
-
33
-
-
77949731645
-
miR-24 regulates apoptosis by targeting the open reading frame (ORF) region of FAF1 in cancer cells
-
Qin W, Shi Y, Zhao B, Yao C, Jin L, et al. (2010) miR-24 regulates apoptosis by targeting the open reading frame (ORF) region of FAF1 in cancer cells. PLoS One 5: e9429.
-
(2010)
PLoS One
, vol.5
-
-
Qin, W.1
Shi, Y.2
Zhao, B.3
Yao, C.4
Jin, L.5
-
34
-
-
65449176088
-
microRNA-24a is required to repress apoptosis in the developing neural retina
-
Walker JC, Harland RM, (2009) microRNA-24a is required to repress apoptosis in the developing neural retina. Genes Dev 23: 1046-1051.
-
(2009)
Genes Dev
, vol.23
, pp. 1046-1051
-
-
Walker, J.C.1
Harland, R.M.2
-
35
-
-
84890439615
-
Preferential star strand biogenesis of pre-miR-24-2 targets PKC-alpha and suppresses cell survival in MCF-7 breast cancer cells
-
Martin EC, Elliott S, Rhodes LV, Antoon JW, Fewell C, et al. (2012) Preferential star strand biogenesis of pre-miR-24-2 targets PKC-alpha and suppresses cell survival in MCF-7 breast cancer cells. Mol Carcinog.
-
(2012)
Mol Carcinog
-
-
Martin, E.C.1
Elliott, S.2
Rhodes, L.V.3
Antoon, J.W.4
Fewell, C.5
-
36
-
-
15444370110
-
Characterization of human NIPK (TRB3, SKIP3) gene activation in stressful conditions
-
Ord D, Ord T, (2005) Characterization of human NIPK (TRB3, SKIP3) gene activation in stressful conditions. Biochemical and Biophysical Research Communications 330: 210-218.
-
(2005)
Biochemical and Biophysical Research Communications
, vol.330
, pp. 210-218
-
-
Ord, D.1
Ord, T.2
-
37
-
-
0038242819
-
TRB3: A tribbles homolog that inhibits Akt/PKB activation by insulin in liver
-
Du KY, Herzig S, Kulkarni RN, Montminy M, (2003) TRB3: A tribbles homolog that inhibits Akt/PKB activation by insulin in liver. Science 300: 1574-1577.
-
(2003)
Science
, vol.300
, pp. 1574-1577
-
-
Du, K.Y.1
Herzig, S.2
Kulkarni, R.N.3
Montminy, M.4
-
38
-
-
33744955437
-
Chronic ethanol intake impairs insulin signaling in rats by disrupting akt association with the cell membrane - Role of TRB3 in inhibition of Akt/protein kinase B activation
-
He L, Simmen FA, Mehendale HM, Ronis MJJ, Badger TM, (2006) Chronic ethanol intake impairs insulin signaling in rats by disrupting akt association with the cell membrane- Role of TRB3 in inhibition of Akt/protein kinase B activation. Journal of Biological Chemistry 281: 11126-11134.
-
(2006)
Journal of Biological Chemistry
, vol.281
, pp. 11126-11134
-
-
He, L.1
Simmen, F.A.2
Mehendale, H.M.3
Ronis, M.J.J.4
Badger, T.M.5
-
39
-
-
32144463321
-
TRB3 is a PI 3-kinase dependent indicator for nutrient starvation
-
Schwarzer R, Dames S, Tondera D, Klippel A, Kaufmann J, (2006) TRB3 is a PI 3-kinase dependent indicator for nutrient starvation. Cellular Signalling 18: 899-909.
-
(2006)
Cellular Signalling
, vol.18
, pp. 899-909
-
-
Schwarzer, R.1
Dames, S.2
Tondera, D.3
Klippel, A.4
Kaufmann, J.5
-
40
-
-
37249059260
-
Critical and functional regulation of CHOP (c/EBP homologous protein) through the N-terminal portion
-
Ohoka N, Hattori T, Kitagawa M, Onozaki K, Hayashi H, (2007) Critical and functional regulation of CHOP (c/EBP homologous protein) through the N-terminal portion. Journal of Biological Chemistry 282: 35687-35694.
-
(2007)
Journal of Biological Chemistry
, vol.282
, pp. 35687-35694
-
-
Ohoka, N.1
Hattori, T.2
Kitagawa, M.3
Onozaki, K.4
Hayashi, H.5
-
41
-
-
34447503956
-
TRB3 inhibits the transcriptional activation of stress-regulated genes by a negative feedback on the ATF4 pathway
-
Jousse C, Deval C, Maurin AC, Parry L, Cherasse Y, et al. (2007) TRB3 inhibits the transcriptional activation of stress-regulated genes by a negative feedback on the ATF4 pathway. Journal of Biological Chemistry 282: 15851-15861.
-
(2007)
Journal of Biological Chemistry
, vol.282
, pp. 15851-15861
-
-
Jousse, C.1
Deval, C.2
Maurin, A.C.3
Parry, L.4
Cherasse, Y.5
-
42
-
-
39849095838
-
E3 ubiquitin ligase SIAH1 mediates ubiquitination and degradation of TRB3
-
Zhou Y, Li L, Liu QM, Xing GC, Kuai XZ, et al. (2008) E3 ubiquitin ligase SIAH1 mediates ubiquitination and degradation of TRB3. Cellular Signalling 20: 942-948.
-
(2008)
Cellular Signalling
, vol.20
, pp. 942-948
-
-
Zhou, Y.1
Li, L.2
Liu, Q.M.3
Xing, G.C.4
Kuai, X.Z.5
-
43
-
-
0035947778
-
Feedback inhibition of the unfolded protein response by GADD34-mediated dephosphorylation of eIF2alpha
-
Novoa I, Zeng H, Harding HP, Ron D, (2001) Feedback inhibition of the unfolded protein response by GADD34-mediated dephosphorylation of eIF2alpha. J Cell Biol 153: 1011-1022.
-
(2001)
J Cell Biol
, vol.153
, pp. 1011-1022
-
-
Novoa, I.1
Zeng, H.2
Harding, H.P.3
Ron, D.4
|