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Volumn 8, Issue 26, 2012, Pages 7024-7035

Simulation of fusion-mediated nanoemulsion interactions with model lipid bilayers

Author keywords

[No Author keywords available]

Indexed keywords

COARSE GRAINED MODELS; COMPLEX FORMATIONS; DELIVERY MECHANISM; DIAGNOSTIC AGENTS; EXPERIMENTAL EVIDENCE; FORCE FIELDS; FUSION PROCESS; HYDROPHOBIC MOIETIES; HYDROPHOBIC MOLECULES; NANO-EMULSIONS; NANOEMULSION; PARTICLE SURFACE; PERFLUOROCARBONS; PHOSPHOLIPID MONOLAYERS; RATE-LIMITING STEPS; SPONTANEOUS CURVATURE; SURFACE CONTACT; TARGET CELLS; TWO PARTICLES;

EID: 84869594603     PISSN: 1744683X     EISSN: 17446848     Source Type: Journal    
DOI: 10.1039/c2sm25847a     Document Type: Article
Times cited : (19)

References (58)
  • 1
    • 68949208465 scopus 로고    scopus 로고
    • Nanocarriers' entry into the cell: Relevance to drug delivery
    • H. Hillaireau P. Couvreur Nanocarriers' entry into the cell: relevance to drug delivery Cell. Mol. Life Sci. 2009 66 17 2873 2896
    • (2009) Cell. Mol. Life Sci. , vol.66 , Issue.17 , pp. 2873-2896
    • Hillaireau, H.1    Couvreur, P.2
  • 2
    • 33846887854 scopus 로고    scopus 로고
    • Internalization of novel non-viral vector TAT-streptavidin into human cells
    • J. Rinne et al., Internalization of novel non-viral vector TAT-streptavidin into human cells BMC Biotechnol. 2007 7 1 1
    • (2007) BMC Biotechnol. , vol.7 , Issue.1 , pp. 1
    • Rinne, J.1
  • 3
    • 33645104169 scopus 로고    scopus 로고
    • Properties of cell penetrating peptides (CPPs)
    • A. Kerkis et al., Properties of cell penetrating peptides (CPPs) IUBMB Life 2006 58 1 7 13
    • (2006) IUBMB Life , vol.58 , Issue.1 , pp. 7-13
    • Kerkis, A.1
  • 4
    • 34547804141 scopus 로고    scopus 로고
    • Gene transfection of mammalian cells using membrane sandwich electroporation
    • DOI 10.1021/ac070482y
    • Z. Fei et al., Gene transfection of mammalian cells using membrane sandwich electroporation Anal. Chem. 2007 79 15 5719 5722 (Pubitemid 47229820)
    • (2007) Analytical Chemistry , vol.79 , Issue.15 , pp. 5719-5722
    • Fei, Z.1    Wang, S.2    Xie, Y.3    Henslee, B.E.4    Chee, G.K.5    Lee, L.J.6
  • 5
    • 37749040157 scopus 로고    scopus 로고
    • Electrophoresis-assisted single-cell electroporation for efficient intracellular delivery
    • C. Ionescu-Zanetti A. Blatz M. Khine Electrophoresis-assisted single-cell electroporation for efficient intracellular delivery Biomed. Microdevices 2008 10 1 113 116
    • (2008) Biomed. Microdevices , vol.10 , Issue.1 , pp. 113-116
    • Ionescu-Zanetti, C.1    Blatz, A.2    Khine, M.3
  • 6
    • 0034946773 scopus 로고    scopus 로고
    • Ultrasound-mediated disruption of cell membranes. I. Quantification of molecular uptake and cell viability
    • DOI 10.1121/1.1376131
    • H. R. Guzman et al., Ultrasound-mediated disruption of cell membranes. I. Quantification of molecular uptake and cell viability J. Acoust. Soc. Am. 2001 110 1 588 596 (Pubitemid 32642595)
    • (2001) Journal of the Acoustical Society of America , vol.110 , Issue.1 , pp. 588-596
    • Guzman, H.R.1    Nguyen, D.X.2    Khan, S.3    Prausnitz, M.R.4
  • 8
    • 3242697895 scopus 로고    scopus 로고
    • The powerful microbubble: From bench to bedside, from intravascular indicator to therapeutic delivery system, and beyond
    • S. B. Feinstein The powerful microbubble: from bench to bedside, from intravascular indicator to therapeutic delivery system, and beyond Am. J. Physiol. 2004 287 2 H450 H457
    • (2004) Am. J. Physiol. , vol.287 , Issue.2
    • Feinstein, S.B.1
  • 9
    • 33746596651 scopus 로고    scopus 로고
    • Acoustic activation of targeted liquid perfluorocarbon nanoparticles does not compromise endothelial integrity
    • DOI 10.1109/TNB.2006.875052, 1637446
    • N. R. Soman et al., Acoustic activation of targeted liquid perfluorocarbon nanoparticles does not compromise endothelial integrity IEEE Trans. Nanobioscience 2006 5 2 69 75 (Pubitemid 44144061)
    • (2006) IEEE Transactions on Nanobioscience , vol.5 , Issue.2 , pp. 69-75
    • Soman, N.R.1    Marsh, J.N.2    Hughes, M.S.3    Lanza, G.M.4    Wickline, S.A.5
  • 10
    • 0034730121 scopus 로고    scopus 로고
    • Diagnostic ultrasound activation of contrast agent gas bodies induces capillary rupture in mice
    • D. L. Miller J. Quddus Diagnostic ultrasound activation of contrast agent gas bodies induces capillary rupture in mice Proc. Natl. Acad. Sci. U. S. A. 2000 97 18 10179 10184
    • (2000) Proc. Natl. Acad. Sci. U. S. A. , vol.97 , Issue.18 , pp. 10179-10184
    • Miller, D.L.1    Quddus, J.2
  • 12
    • 42549113101 scopus 로고    scopus 로고
    • New mechanisms for non-porative ultrasound stimulation of cargo delivery to cell cytosol with targeted perfluorocarbon nanoparticles
    • N. R. Soman et al., New mechanisms for non-porative ultrasound stimulation of cargo delivery to cell cytosol with targeted perfluorocarbon nanoparticles Nanotechnology 2008 19 18 185102
    • (2008) Nanotechnology , vol.19 , Issue.18 , pp. 185102
    • Soman, N.R.1
  • 13
    • 77049101923 scopus 로고    scopus 로고
    • Mechanisms of nucleotide trafficking during siRNA delivery to endothelial cells using perfluorocarbon nanoemulsions
    • M. M. Kaneda et al., Mechanisms of nucleotide trafficking during siRNA delivery to endothelial cells using perfluorocarbon nanoemulsions Biomaterials 2010 31 11 3079 3086
    • (2010) Biomaterials , vol.31 , Issue.11 , pp. 3079-3086
    • Kaneda, M.M.1
  • 14
    • 44349193333 scopus 로고    scopus 로고
    • Exploiting lipid raft transport with membrane targeted nanoparticles: A strategy for cytosolic drug delivery
    • K. C. Partlow G. M. Lanza S. A. Wickline Exploiting lipid raft transport with membrane targeted nanoparticles: a strategy for cytosolic drug delivery Biomaterials 2008 29 23 3367 3375
    • (2008) Biomaterials , vol.29 , Issue.23 , pp. 3367-3375
    • Partlow, K.C.1    Lanza, G.M.2    Wickline, S.A.3
  • 15
    • 43649093151 scopus 로고    scopus 로고
    • +-lipid interactions and finite size effects
    • +-lipid interactions and finite size effects Biophys. J. 2008 94 9 3565 3576
    • (2008) Biophys. J. , vol.94 , Issue.9 , pp. 3565-3576
    • Lee, S.-J.1    Song, Y.2    Baker, N.A.3
  • 17
    • 67949098831 scopus 로고    scopus 로고
    • Perturbations of membrane structure by cholesterol and cholesterol derivatives are determined by sterol orientation
    • B. N. Olsen P. H. Schlesinger N. A. Baker Perturbations of membrane structure by cholesterol and cholesterol derivatives are determined by sterol orientation J. Am. Chem. Soc. 2009 131 13 4854 4865
    • (2009) J. Am. Chem. Soc. , vol.131 , Issue.13 , pp. 4854-4865
    • Olsen, B.N.1    Schlesinger, P.H.2    Baker, N.A.3
  • 18
    • 26644433416 scopus 로고    scopus 로고
    • Molecular dynamics simulations of salicylate effects on the micro- and mesoscopic properties of a dipalmitoylphosphatidylcholine bilayer
    • DOI 10.1021/bi0506829
    • Y. Song V. Guallar N. A. Baker Molecular dynamics simulations of salicylate effects on the micro- and mesoscopic properties of a dipalmitoylphosphatidylcholine bilayer Biochemistry 2005 44 41 13425 13438 (Pubitemid 41443670)
    • (2005) Biochemistry , vol.44 , Issue.41 , pp. 13425-13438
    • Song, Y.1    Guallar, V.2    Baker, N.A.3
  • 19
    • 1642485164 scopus 로고    scopus 로고
    • Coarse grained model for semiquantitative lipid simulations
    • S. J. Marrink A. H. de Vries A. E. Mark Coarse grained model for semiquantitative lipid simulations J. Phys. Chem. B 2004 108 2 750 760
    • (2004) J. Phys. Chem. B , vol.108 , Issue.2 , pp. 750-760
    • Marrink, S.J.1    De Vries, A.H.2    Mark, A.E.3
  • 21
    • 0345098288 scopus 로고    scopus 로고
    • Molecular Dynamics Simulation of the Formation, Structure, and Dynamics of Small Phospholipid Vesicles
    • DOI 10.1021/ja0352092
    • S. J. Marrink A. E. Mark Molecular dynamics simulation of the formation, structure, and dynamics of small phospholipid vesicles J. Am. Chem. Soc. 2003 125 49 15233 15242 (Pubitemid 37509686)
    • (2003) Journal of the American Chemical Society , vol.125 , Issue.49 , pp. 15233-15242
    • Marrink, S.J.1    Mark, A.E.2
  • 22
    • 14544291957 scopus 로고    scopus 로고
    • A multiscale coarse-graining method for biomolecular systems
    • DOI 10.1021/jp044629q
    • S. Izvekov G. A. Voth A multiscale coarse-graining method for biomolecular systems J. Phys. Chem. B 2005 109 7 2469 2473 (Pubitemid 40304419)
    • (2005) Journal of Physical Chemistry B , vol.109 , Issue.7 , pp. 2469-2473
    • Izvekov, S.1    Voth, G.A.2
  • 23
    • 0036154247 scopus 로고    scopus 로고
    • Stalk model of membrane fusion: Solution of energy crisis
    • Y. Kozlovsky M. M. Kozlov Stalk model of membrane fusion: solution of energy crisis Biophys. J. 2002 82 2 882 895 (Pubitemid 34111229)
    • (2002) Biophysical Journal , vol.82 , Issue.2 , pp. 882-895
    • Kozlovsky, Y.1    Kozlov, M.M.2
  • 26
    • 77956067803 scopus 로고    scopus 로고
    • Splaying of aliphatic tails plays a central role in barrier crossing during liposome fusion
    • D. Mirjanian et al., Splaying of aliphatic tails plays a central role in barrier crossing during liposome fusion J. Phys. Chem. B 2010 114 34 11061 11068
    • (2010) J. Phys. Chem. B , vol.114 , Issue.34 , pp. 11061-11068
    • Mirjanian, D.1
  • 27
    • 77955486396 scopus 로고    scopus 로고
    • Atomic-resolution simulations predict a transition state for vesicle fusion defined by contact of a few lipid tails
    • P. M. Kasson E. Lindahl V. S. Pande Atomic-resolution simulations predict a transition state for vesicle fusion defined by contact of a few lipid tails PLoS Comput. Biol. 2010 6 6 e1000829
    • (2010) PLoS Comput. Biol. , vol.6 , Issue.6 , pp. 1000829
    • Kasson, P.M.1    Lindahl, E.2    Pande, V.S.3
  • 28
    • 80052539628 scopus 로고    scopus 로고
    • Low density lipoprotein: Structure, dynamics, and interactions of apoB-100 with lipids
    • T. Murtola et al., Low density lipoprotein: structure, dynamics, and interactions of apoB-100 with lipids Soft Matter 2012 7 18 8135 8141
    • (2012) Soft Matter , vol.7 , Issue.18 , pp. 8135-8141
    • Murtola, T.1
  • 29
    • 78349243645 scopus 로고    scopus 로고
    • Role of lipids in spheroidal high density lipoproteins
    • p.
    • T. Vuorela, et al., Role of lipids in spheroidal high density lipoproteins, PLoS Comput. Biol., 2010, 6 (10), p. e1000964
    • (2010) PLoS Comput. Biol. , vol.6 , Issue.10 , pp. 1000964
    • Vuorela, T.1
  • 30
    • 58149471766 scopus 로고    scopus 로고
    • Molecular dynamics study of a phospholipid monolayer at a water-triglyceride interface: Towards lipid emulsion modelling
    • G. Henneré et al., Molecular dynamics study of a phospholipid monolayer at a water-triglyceride interface: towards lipid emulsion modelling Chem. Phys. Lipids 2009 157 2 86 93
    • (2009) Chem. Phys. Lipids , vol.157 , Issue.2 , pp. 86-93
    • Henneré, G.1
  • 31
    • 27544473312 scopus 로고    scopus 로고
    • Membrane hemifusion: Crossing a chasm in two leaps
    • DOI 10.1016/j.cell.2005.10.015, PII S0092867405010901
    • L. V. Chernomordik M. M. Kozlov Membrane hemifusion: crossing a chasm in two leaps Cell 2005 123 3 375 382 (Pubitemid 41546669)
    • (2005) Cell , vol.123 , Issue.3 , pp. 375-382
    • Chernomordik, L.V.1    Kozlov, M.M.2
  • 33
    • 0035465476 scopus 로고    scopus 로고
    • Oxygen Carriers ("Blood Substitutes") Raison d'Etre, Chemistry, and Some Physiology Blut ist ein ganz besondrer Saft 1
    • J. G. Riess Oxygen Carriers ("Blood Substitutes") Raison d'Etre, Chemistry, and Some Physiology Blut ist ein ganz besondrer Saft 1 Chem. Rev. 2001 101 9 2797 2920
    • (2001) Chem. Rev. , vol.101 , Issue.9 , pp. 2797-2920
    • Riess, J.G.1
  • 34
    • 0025006946 scopus 로고
    • Physical and acoustical properties of perfluorooctylbromide, an ultrasound contrast agent
    • M. Andre T. Nelson R. Mattrey Physical and acoustical properties of perfluorooctylbromide, an ultrasound contrast agent Invest. Radiol. 1990 25 9 983 987 (Pubitemid 20274018)
    • (1990) Investigative Radiology , vol.25 , Issue.9 , pp. 983-987
    • Andre, M.1    Nelson, T.2    Mattrey, R.3
  • 38
    • 46249092554 scopus 로고    scopus 로고
    • GROMACS 4: Algorithms for highly efficient, load-balanced, and scalable molecular simulation
    • B. Hess et al., GROMACS 4: algorithms for highly efficient, load-balanced, and scalable molecular simulation J. Chem. Theory Comput. 2008 4 3 435 447
    • (2008) J. Chem. Theory Comput. , vol.4 , Issue.3 , pp. 435-447
    • Hess, B.1
  • 39
    • 33750587438 scopus 로고
    • Molecular dynamics with coupling to an external bath
    • H. J. C. Berendsen et al., Molecular dynamics with coupling to an external bath J. Chem. Phys. 1984 81 8 3684 3690
    • (1984) J. Chem. Phys. , vol.81 , Issue.8 , pp. 3684-3690
    • Berendsen, H.J.C.1
  • 40
    • 36949024736 scopus 로고    scopus 로고
    • Control of membrane fusion mechanism by lipid composition: Predictions from ensemble molecular dynamics
    • preprint(2007)
    • P. Kasson V. S. Pande Control of membrane fusion mechanism by lipid composition: predictions from ensemble molecular dynamics PLoS Comput. Biol. 2005 e220
    • (2005) PLoS Comput. Biol. , pp. 220
    • Kasson, P.1    Pande, V.S.2
  • 41
    • 77955312522 scopus 로고    scopus 로고
    • Characterization of perfluorooctylbromide-based nanoemulsion particles using atomistic molecular dynamics simulations
    • S.-J. Lee et al., Characterization of perfluorooctylbromide-based nanoemulsion particles using atomistic molecular dynamics simulations J. Phys. Chem. B 2010 114 31 10086 10096
    • (2010) J. Phys. Chem. B , vol.114 , Issue.31 , pp. 10086-10096
    • Lee, S.-J.1
  • 42
    • 62349108909 scopus 로고    scopus 로고
    • Curvature effects on lipid packing and dynamics in liposomes revealed by coarse grained molecular dynamics simulations
    • J. Risselada S. Marrink Curvature effects on lipid packing and dynamics in liposomes revealed by coarse grained molecular dynamics simulations Phys. Chem. Chem. Phys. 2009 11 12 2056 2067
    • (2009) Phys. Chem. Chem. Phys. , vol.11 , Issue.12 , pp. 2056-2067
    • Risselada, J.1    Marrink, S.2
  • 43
    • 0001563901 scopus 로고
    • Molecular dynamics simulation of a smectic liquid crystal with atomic detail
    • E. Egberts H. J. C. Berendsen Molecular dynamics simulation of a smectic liquid crystal with atomic detail J. Chem. Phys. 1988 89 6 3718 3732
    • (1988) J. Chem. Phys. , vol.89 , Issue.6 , pp. 3718-3732
    • Egberts, E.1    Berendsen, H.J.C.2
  • 44
    • 77955312522 scopus 로고    scopus 로고
    • Characterization of perfluorooctylbromide-based nanoemulsion particles using atomistic molecular dynamics simulations
    • S.-J. Lee et al., Characterization of perfluorooctylbromide-based nanoemulsion particles using atomistic molecular dynamics simulations J. Phys. Chem. B 2010 114 31 10086 10096
    • (2010) J. Phys. Chem. B , vol.114 , Issue.31 , pp. 10086-10096
    • Lee, S.-J.1
  • 45
    • 34250322707 scopus 로고    scopus 로고
    • Molecular dynamics simulations of lipid vesicle fusion in atomic detail
    • DOI 10.1529/biophysj.106.103572
    • V. Knecht S.-J. Marrink Molecular dynamics simulations of lipid vesicle fusion in atomic detail Biophys. J. 2007 92 12 4254 4261 (Pubitemid 46910541)
    • (2007) Biophysical Journal , vol.92 , Issue.12 , pp. 4254-4261
    • Knecht, V.1    Marrink, S.-J.2
  • 46
    • 0020482336 scopus 로고
    • Minimal size phosphatidylcholine vesicles: Effects of radius of curvature on head group packing and conformation
    • C. G. Brouillette et al., Minimal size phosphatidylcholine vesicles: effects of radius of curvature on head group packing and conformation Biochemistry 1982 21 19 4569 4575
    • (1982) Biochemistry , vol.21 , Issue.19 , pp. 4569-4575
    • Brouillette, C.G.1
  • 48
    • 34249933061 scopus 로고    scopus 로고
    • How synaptotagmin promotes membrane fusion
    • DOI 10.1126/science.1142614
    • S. Martens M. M. Kozlov H. T. McMahon How synaptotagmin promotes membrane fusion Science 2007 316 5828 1205 1208 (Pubitemid 46877485)
    • (2007) Science , vol.316 , Issue.5828 , pp. 1205-1208
    • Martens, S.1    Kozlov, M.M.2    McMahon, H.T.3
  • 49
    • 68749083522 scopus 로고    scopus 로고
    • 2+-regulated fusion
    • 2+-regulated fusion Cell 2009 138 4 709 721
    • (2009) Cell , vol.138 , Issue.4 , pp. 709-721
    • Hui, E.1
  • 50
    • 44449136550 scopus 로고    scopus 로고
    • Synthesis and characterization of stable fluorocarbon nanostructures as drug delivery vehicles for cytolytic peptides
    • N. R. Soman et al., Synthesis and characterization of stable fluorocarbon nanostructures as drug delivery vehicles for cytolytic peptides Nano Lett. 2008 8 1131 1136
    • (2008) Nano Lett. , vol.8 , pp. 1131-1136
    • Soman, N.R.1
  • 51
    • 28844495352 scopus 로고    scopus 로고
    • Sonic activation of molecularly-targeted nanoparticles accelerates transmembrane lipid delivery to cancer cells through contact-mediated mechanisms: Implications for enhanced local drug delivery
    • DOI 10.1016/j.ultrasmedbio.2005.07.022, PII S030156290500308X
    • K. Crowder et al., Sonic activation of molecularly targeted nanoparticles accelerates transmembrane lipid delivery to cancer cells through contact-mediated mechanisms: implications for enhanced local drug delivery. Ultrasound Med. Biol. 2005 31 12 1693 1700 (Pubitemid 41774687)
    • (2005) Ultrasound in Medicine and Biology , vol.31 , Issue.12 , pp. 1693-1700
    • Crowder, K.C.1    Hughes, M.S.2    Marsh, J.N.3    Barbieri, A.M.4    Fuhrhop, R.W.5    Lanza, G.M.6    Wickline, S.A.7
  • 52
    • 70349220917 scopus 로고    scopus 로고
    • Molecularly targeted nanocarriers deliver the cytolytic peptide melittin specifically to tumor cells in mice, reducing tumor growth
    • N. R. Soman et al., Molecularly targeted nanocarriers deliver the cytolytic peptide melittin specifically to tumor cells in mice, reducing tumor growth J. Clin. Invest. 2009 119 9 2830 2842
    • (2009) J. Clin. Invest. , vol.119 , Issue.9 , pp. 2830-2842
    • Soman, N.R.1
  • 53
    • 33847166920 scopus 로고    scopus 로고
    • Noncavitational mechanisms of interaction of ultrasound with targeted perfluorocarbon nanoparticles: Implications for drug delivery
    • DOI 10.1109/ULTSYM.2005.1603195, 1603195, 2005 IEEE Ultrasonics Symposium
    • N. R. Soman et al., Noncavitational mechanisms of interaction of ultrasound with targeted perfluorocarbon nanoparticles: implications for drug delivery IEEE Int. Ultrason. Symp. 2005 vol. 3 1712 1715 (Pubitemid 46285151)
    • (2005) Proceedings - IEEE Ultrasonics Symposium , vol.3 , pp. 1712-1715
    • Soman, N.R.1    Marsh, J.N.2    Hughes, M.S.3    Lanza, G.M.4    Wickline, S.A.5
  • 54
    • 0031740415 scopus 로고    scopus 로고
    • Hydrophobic mismatch between proteins and lipids in membranes
    • K. J. Antoinette Hydrophobic mismatch between proteins and lipids in membranes Biochim. Biophys. Acta, Rev. Biomembr. 1998 1376 3 401 416
    • (1998) Biochim. Biophys. Acta, Rev. Biomembr. , vol.1376 , Issue.3 , pp. 401-416
    • Antoinette, K.J.1
  • 55
    • 70349221698 scopus 로고    scopus 로고
    • Perfluorocarbon nanoemulsions for quantitative molecular imaging and targeted therapeutics
    • M. Kaneda et al., Perfluorocarbon nanoemulsions for quantitative molecular imaging and targeted therapeutics Ann. Biomed. Eng. 2009 37 10 1922 1933
    • (2009) Ann. Biomed. Eng. , vol.37 , Issue.10 , pp. 1922-1933
    • Kaneda, M.1
  • 56
    • 46549104564 scopus 로고
    • The shape of lipid molecules and monolayer membrane fusion
    • L. V. Chernomordik et al., The shape of lipid molecules and monolayer membrane fusion Biochim. Biophys. Acta, Biomembr. 1985 812 3 643 655
    • (1985) Biochim. Biophys. Acta, Biomembr. , vol.812 , Issue.3 , pp. 643-655
    • Chernomordik, L.V.1
  • 57
    • 0344467181 scopus 로고    scopus 로고
    • Modeling alkane + perfluoroalkane interactions using all-atom potentials: Failure of the usual combining rules
    • W. Song P. J. Rossky M. Maroncelli Modeling alkane + perfluoroalkane interactions using all-atom potentials: failure of the usual combining rules J. Chem. Phys. 2003 119 17 9145 9162
    • (2003) J. Chem. Phys. , vol.119 , Issue.17 , pp. 9145-9162
    • Song, W.1    Rossky, P.J.2    Maroncelli, M.3
  • 58
    • 0037180413 scopus 로고    scopus 로고
    • Targeted antiproliferative drug delivery to vascular smooth muscle cells with a magnetic resonance imaging nanoparticle contrast agent: Implications for rational therapy of restenosis
    • DOI 10.1161/01.CIR.0000044020.27990.32
    • G. M. Lanza X. Yu P. M. Winter D. R. Abendschein K. K. Karukstis M. J. Scott L. K. Chinen R. W. Fuhrhop D. E. Scherrer S. A. Wickline Targeted antiproliferative drug delivery to vascular smooth muscle cells with a magnetic resonance imaging nanoparticle contrast agent Circulation 2002 106 22 2842 2847 (Pubitemid 35396985)
    • (2002) Circulation , vol.106 , Issue.22 , pp. 2842-2847
    • Lanza, G.M.1    Yu, X.2    Winter, P.M.3    Abendschein, D.R.4    Karukstis, K.K.5    Scott, M.J.6    Chinen, L.K.7    Fuhrhop, R.W.8    Scherrer, D.E.9    Wickline, S.A.10


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