Atomic-Resolution simulations predict a transition state for vesicle fusion defined by contact of a few lipid tails

PLoS Computational Biology

Volumn 6, Issue 6, 2010, Pages 1-11

  Kasson, Peter M ^a,b   Lindahl, Erik ^b   Pande, Vijay S ^a  

^a STANFORD UNIVERSITY   (United States)

^b STOCKHOLM UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ATOMS; CELL MEMBRANES; INTERFACE STATES; PEPTIDES; VIRUSES;

ATOMIC-RESOLUTION; CATALYSE; CELLULARS; ENVELOPED VIRUS; FUSION PROTEINS; MEMBRANE FUSION; PROTEIN ASSEMBLY; TRANSITION STATE; VESICLE FUSION; VESICLE TRAFFICKING;

LIPID BILAYERS;

HYBRID PROTEIN; LIPID; PEPTIDE DERIVATIVE; VIRUS FUSION PROTEIN; 1 PALMITOYL 2 OLEOYLPHOSPHATIDYLETHANOLAMINE; 1-PALMITOYL-2-OLEOYLPHOSPHATIDYLCHOLINE; 1-PALMITOYL-2-OLEOYLPHOSPHATIDYLETHANOLAMINE; 2 OLEOYL 1 PALMITOYLPHOSPHATIDYLCHOLINE; PHOSPHATIDYLCHOLINE; PHOSPHATIDYLETHANOLAMINE; VIRUS HEMAGGLUTININ; WATER;

ANALYTIC METHOD; ARTICLE; CATALYSIS; CELL VACUOLE; HYDROPHILICITY; HYDROPHOBICITY; INFLUENZA; LIPID BILAYER; MEMBRANE FUSION; MOLECULAR BIOLOGY; PREDICTION; PROTEIN FUNCTION; PROTEIN LIPID INTERACTION; PROTEIN STRUCTURE; SIMULATION; CHEMICAL STRUCTURE; CHEMISTRY; COMPUTER SIMULATION; METABOLISM; ORTHOMYXOVIRUS; PHYSIOLOGY; TRANSPORT VESICLE;

COMPUTER SIMULATION; HEMAGGLUTININS, VIRAL; HYDROPHOBICITY; MEMBRANE FUSION; MODELS, MOLECULAR; ORTHOMYXOVIRIDAE; PHOSPHATIDYLCHOLINES; PHOSPHATIDYLETHANOLAMINES; TRANSPORT VESICLES; WATER;

EID: 77955486396     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1000829     Document Type: Article

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