Mechanisms of nucleotide trafficking during siRNA delivery to endothelial cells using perfluorocarbon nanoemulsions

Biomaterials

Volumn 31, Issue 11, 2010, Pages 3079-3086

  Kaneda, Megan M ^a   Sasaki, Yo ^a   Lanza, Gregory M ^a   Milbrandt, Jeffrey ^a   Wickline, Samuel A ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Drug delivery; Endothelial cell; Gene therapy; Nanoparticle

Indexed keywords

ADHESION MOLECULES; CELL TRAFFICKING; CYTOSOLS; HEMIFUSION; IN-VITRO; LIPID RAFT; NANO-EMULSIONS; PERFLUOROCARBONS; RESEARCH TOOLS; RNA INTERFERENCE; SIRNA DELIVERY; THERAPEUTIC AGENTS; TRANSFECTION AGENTS; TRANSFECTION REAGENTS;

BLOOD VESSEL PROSTHESES; CELL MEMBRANES; COMPLEXATION; CYTOLOGY; DRUG DELIVERY; GENE EXPRESSION; GENE THERAPY; GENETIC ENGINEERING; NANOPARTICLES; NUCLEIC ACIDS; RNA; SELF ASSEMBLY;

ENDOTHELIAL CELLS;

1,2 DIOLEOYL 3 TRIMETHYLAMMONIOPROPANE; 1,4,7,10 TETRAAZACYCLODODECANE 1,4,7,10 TETRAACETIC ACID; FLUOROCARBON; LIPOFECTAMINE; NANOPARTICLE; SMALL INTERFERING RNA; VASCULAR CELL ADHESION MOLECULE 1;

ANIMAL CELL; ARTICLE; CELL INTERACTION; CONTROLLED STUDY; CYTOSOL; DRUG DELIVERY SYSTEM; ENDOTHELIUM CELL; GENETIC TRANSFECTION; LIPID RAFT; MOUSE; NANOEMULSION; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RNA INTERFERENCE; RNA TRANSPORT; UPREGULATION; WESTERN BLOTTING; ZETA POTENTIAL;

ANIMALS; CATIONS; CELL LINE; CELL MEMBRANE STRUCTURES; DRUG CARRIERS; EMULSIONS; ENDOTHELIAL CELLS; FLUOROCARBONS; INDICATORS AND REAGENTS; LIPIDS; MICE; NANOPARTICLES; NUCLEOTIDES; RNA INTERFERENCE; RNA, SMALL INTERFERING; TRANSFECTION;

EID: 77049101923     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2010.01.006     Document Type: Article

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