Hip geometry in diabetic women: Implications for fracture risk

Metabolism: Clinical and Experimental

Volumn 61, Issue 12, 2012, Pages 1756-1762

  Garg, Rajesh ^a   Chen, Zhao ^b   Beck, Thomas ^c   Cauley, Jane A ^d   Wu, Guanglin ^b   Nelson, Dorothy ^e   Lewis, Beth ^f   Lacroix, Andrea ^g   Leboff, Meryl S ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b UNIVERSITY OF ARIZONA   (United States)

^c Quantum Medical Metrics   (United States)

^d UNIVERSITY OF PITTSBURGH   (United States)

^e OAKLAND UNIVERSITY   (United States)

^f UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^g Fred Hutchinson Cancer Research Center   (United States)

Author keywords

Bone Geometry; Diabetes mellitus; Hip structural analysis; Women's Health Initiative Study

Indexed keywords

INSULIN; ORAL ANTIDIABETIC AGENT;

ADULT; ARTICLE; BONE DENSITY; BONE SCINTISCANNING; BONE STRENGTH; BONE STRUCTURE; COMPARATIVE STUDY; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; DIABETIC PATIENT; DUAL ENERGY X RAY ABSORPTIOMETRY; FEMALE; FRACTURE; GEOMETRY; HEIGHT; HIP; HUMAN; LEAN BODY WEIGHT; MAJOR CLINICAL STUDY; NON INSULIN DEPENDENT DIABETES MELLITUS; PRIORITY JOURNAL; RISK ASSESSMENT;

ABSORPTIOMETRY, PHOTON; AGED; BODY COMPOSITION; BONE DENSITY; BONE REMODELING; CROSS-SECTIONAL STUDIES; DIABETES MELLITUS, TYPE 2; DIABETIC DIET; FEMALE; FEMORAL NECK FRACTURES; FEMUR NECK; HUMANS; HYPOGLYCEMIC AGENTS; MIDDLE AGED; POSTMENOPAUSE; RISK ASSESSMENT; RISK FACTORS; TENSILE STRENGTH; WOMEN'S HEALTH;

EID: 84869508757     PISSN: 00260495     EISSN: 15328600     Source Type: Journal    
DOI: 10.1016/j.metabol.2012.05.010     Document Type: Article

References (35)

1. http://www.who.int/mediacentre/factsheets/fs312/en/.
2. http://www.iofbonehealth.org/health-professionals/about-osteoporosis/ epidemiology.html.
3. I.I. de Liefde, M. van der Klift, and C.E. de Laet Bone mineral density and fracture risk in type-2 diabetes mellitus: the Rotterdam Study Osteoporos Int 16 12 2005 1713 1720 (Pubitemid 41790880)
4. E.S. Strotmeyer, J.A. Cauley, and A.V. Schwartz Diabetes is associated independently of body composition with BMD and bone volume in older white and black men and women: the Health, Aging, and Body Composition Study J Bone Miner Res 19 7 2004 1084 1091 (Pubitemid 41110559)
5. E.S. Strotmeyer, J.A. Cauley, and A.V. Schwartz Nontraumatic fracture risk with diabetes mellitus and impaired fasting glucose in older white and black adults: the health, aging, and body composition study Arch Intern Med 165 14 2005 1612 1617 (Pubitemid 41124155)
6. J. Robbins, A.K. Aragaki, and C. Kooperberg Factors associated with 5-year risk of hip fracture in postmenopausal women JAMA 298 20 2007 2389 2398 (Pubitemid 350190780)
7. L.L. Lipscombe, S.A. Jamal, and G.L. Booth The risk of hip fractures in older individuals with diabetes: a population-based study Diabetes Care 30 4 2007 835 841 (Pubitemid 46556575)
8. D.E. Bonds, J.C. Larson, and A.V. Schwartz Risk of fracture in women with type 2 diabetes: the Women's Health Initiative Observational Study J Clin Endocrinol Metab 91 9 2006 3404 3410 (Pubitemid 44402111)
9. P. Vestergaard Discrepancies in bone mineral density and fracture risk in patients with type 1 and type 2 diabetes - a meta-analysis Osteoporos Int 18 4 2007 427 444 (Pubitemid 46354916)
10. A.V. Schwartz, E. Vittinghoff, and D.C. Bauer Association of BMD and FRAX score with risk of fracture in older adults with type 2 diabetes JAMA 305 21 2011 2184 2192
11. M.L. Bouxsein Mechanisms of osteoporosis therapy: a bone strength perspective Clin Cornerstone Suppl. 2 2003 S13 S21
12. L.J. Melton III, T.J. Beck, and S. Amin Contributions of bone density and structure to fracture risk assessment in men and women Osteoporos Int 16 5 2005 460 467
13. S. Ishii, J.A. Cauley, and C.J. Crandall Diabetes and femoral neck strength: findings from the Hip Strength Across the Menopausal Transition Study J Clin Endocrinol Metab 97 1 2012 190 197
14. T.J. Beck, C.B. Ruff, and K.E. Warden Predicting femoral neck strength from bone mineral data. A structural approach Invest Radiol 25 1 1990 6 18 (Pubitemid 20040519)
15. Z. Chen, L. Qi, and T.J. Beck Stronger bone correlates with African admixture in African-American women J Bone Miner Res 26 9 2011 2307 2316
16. D.A. Nelson, T.J. Beck, and G. Wu Ethnic differences in femur geometry in the women's health initiative observational study Osteoporos Int 22 5 2011 1377 1388
17. R.B. Martin, and D.B. Burr Non-invasive measurement of long bone cross-sectional moment of inertia by photon absorptiometry J Biomech 17 3 1984 195 201 (Pubitemid 14149624)
18. T.J. Beck, M.A. Petit, and G. Wu Does obesity really make the femur stronger? BMD, geometry, and fracture incidence in the women's health initiative-observational study J Bone Miner Res 24 8 2009 1369 1379
19. T.G. Travison, A.B. Araujo, and G.R. Esche Lean mass and not fat mass is associated with male proximal femur strength J Bone Miner Res 23 2 2008 189 198 (Pubitemid 351160032)
20. T.J. Beck, T.L. Oreskovic, and K.L. Stone Structural adaptation to changing skeletal load in the progression toward hip fragility: the study of osteoporotic fractures J Bone Miner Res 16 6 2001 1108 1119 (Pubitemid 32467155)
21. K.F. Moseley, D.A. Dobrosielski, and K.J. Stewart Lean mass predicts hip geometry in men and women with non-insulin-requiring type 2 diabetes mellitus J Clin Densitom 14 3 2011 332 339
22. A.J. Burghardt, A.S. Issever, and A.V. Schwartz High-resolution peripheral quantitative computed tomographic imaging of cortical and trabecular bone microarchitecture in patients with type 2 diabetes mellitus J Clin Endocrinol Metab 95 11 2010 5045 5055
23. S.W. Park, B.H. Goodpaster, and E.S. Strotmeyer Decreased muscle strength and quality in older adults with type 2 diabetes: the health, aging, and body composition study Diabetes 55 6 2006 1813 1818 (Pubitemid 44324137)
24. F. Elefteriou, J.D. Ahn, and S. Takeda Leptin regulation of bone resorption by the sympathetic nervous system and CART Nature 434 7032 2005 514 520 (Pubitemid 40477060)
25. S. Patel, S. Hyer, and K. Tweed Risk factors for fractures and falls in older women with type 2 diabetes mellitus Calcif Tissue Int 82 2 2008 87 91
26. A.V. Schwartz, and D.E. Sellmeyer Diabetes, fracture, and bone fragility Curr Osteoporos Rep 5 3 2007 105 111 (Pubitemid 47571960)
27. K.E. Barbour, J.M. Zmuda, and R. Boudreau Adipokines and the risk of fracture in older adults J Bone Miner Res 26 7 2011 1568 1576
28. N. Napoli, C. Pedone, and P. Pozzilli Adiponectin and bone mass density: the InCHIANTI study Bone 47 6 2010 1001 1005
29. I. Kanazawa, T. Yamaguchi, and T. Sugimoto Baseline serum total adiponectin level is positively associated with changes in bone mineral density after 1-year treatment of type 2 diabetes mellitus Metabolism 59 9 2010 1252 1256
30. M.D. Kontogianni, U.G. Dafni, and J.G. Routsias Blood leptin and adiponectin as possible mediators of the relation between fat mass and BMD in perimenopausal women J Bone Miner Res 19 4 2004 546 551 (Pubitemid 41071213)
31. O. Vasilkova, T. Mokhort, and T. Sharshakova Leptin is an independent determinant of bone mineral density in men with type 2 diabetes mellitus Acta Diabetol 48 4 2011 291 295
32. G.M. Pieper, and H. Riaz-ul-Haq Activation of nuclear factor-kappaB in cultured endothelial cells by increased glucose concentration: prevention by calphostin C J Cardiovasc Pharmacol 30 4 1997 528 532 (Pubitemid 27527591)
33. J.A. Cauley, M.E. Danielson, and R.M. Boudreau Inflammatory markers and incident fracture risk in older men and women: the Health Aging and Body Composition Study J Bone Miner Res 22 7 2007 1088 1095 (Pubitemid 351339731)
34. S.Y. Tang, and D. Vashishth Non-enzymatic glycation alters microdamage formation in human cancellous bone Bone 46 1 2010 148 154
35. M. Yamamoto, T. Yamaguchi, and M. Yamauchi Low serum level of the endogenous secretory receptor for advanced glycation end products (esRAGE) is a risk factor for prevalent vertebral fractures independent of bone mineral density in patients with type 2 diabetes Diabetes Care 32 12 2009 2263 2268