Characterization of solid polymer dispersions of active pharmaceutical ingredients by 19F MAS NMR and factor analysis

Spectrochimica Acta - Part A: Molecular and Biomolecular Spectroscopy

Volumn 100, Issue , 2013, Pages 59-66

  Urbanova, Martina ^a   Brus, Jiri ^a   Sedenkova, Ivana ^a   Policianova, Olivia ^a   Kobera, Libor ^a  

^a INSTITUTE OF MACROMOLECULAR CHEMISTRY   (Czech Republic)

Author keywords

19F MAS NMR; API; Factor analysis; Magnetic susceptibility; Solid dispersions; Solid state NMR

Indexed keywords

ACTIVE PHARMACEUTICAL INGREDIENTS; API; ATORVASTATIN; CHEMOMETRIC APPROACH; ELECTRON CLOUDS; HIGH FREQUENCY HF; MAS NMR; MAS-NMR SPECTROSCOPY; MODEL SYSTEM; MOLECULAR ARRANGEMENTS; MULTI VARIATE ANALYSIS; NANOSIZED DOMAINS; POLYMER MATRICES; POORLY WATER-SOLUBLE DRUGS; SOLID DISPERSION; SOLID POLYMERS; SOLID STATE NMR; SPECTRAL CONTRIBUTION; STRUCTURAL DIFFERENCES; STRUCTURAL VARIABILITY;

DISPERSIONS; FACTOR ANALYSIS; MAGNETIC SUSCEPTIBILITY; MULTIVARIANT ANALYSIS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

APPLICATION PROGRAMMING INTERFACES (API);

ATORVASTATIN; DRUG; FLUORINE; HEPTANOIC ACID DERIVATIVE; POVIDONE; PYRROLE DERIVATIVE;

CHEMISTRY; CONFERENCE PAPER; CRYSTALLIZATION; FACTORIAL ANALYSIS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; TIME;

CRYSTALLIZATION; FACTOR ANALYSIS, STATISTICAL; FLUORINE; HEPTANOIC ACIDS; MAGNETIC RESONANCE SPECTROSCOPY; PHARMACEUTICAL PREPARATIONS; POVIDONE; PYRROLES; TIME FACTORS;

EID: 84869502830     PISSN: 13861425     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.saa.2012.02.057     Document Type: Conference Paper

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