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Volumn 3, Issue 6, 2003, Pages 897-907

Anhydrates and Hydrates of Olanzapine: Crystallization, Solid-State Characterization, and Structural Relationships

Author keywords

[No Author keywords available]

Indexed keywords

OLANZAPINE;

EID: 0344583871     PISSN: 15287483     EISSN: None     Source Type: Journal    
DOI: 10.1021/cg034055z     Document Type: Article
Times cited : (122)

References (57)
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  • 27
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    • Cambridge Crystallographic Data Centre: Cambridge, UK, November update
    • Cambridge Structural Database, Version 5.24; Cambridge Crystallographic Data Centre: Cambridge, UK, November 2002 update.
    • (2002) Cambridge Structural Database, Version 5.24
  • 34
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    • (1998) SMART, Version 5.05
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    • Bruker AXS, Inc.: Madison, Wisconsin
    • SAINT, Version 6.2, Bruker AXS, Inc.: Madison, Wisconsin, 2001.
    • (2001) SAINT, Version 6.2
  • 37
    • 0344756921 scopus 로고    scopus 로고
    • note
    • The crystal structure of the EtOH-water solvate will be disclosed in a separate report.
  • 40
    • 0003422019 scopus 로고
    • Wavefunction, Inc.: Irvine, CA
    • Spartan, Version 5.0; Wavefunction, Inc.: Irvine, CA, 1992.
    • (1992) Spartan, Version 5.0
  • 41
    • 37049105897 scopus 로고
    • Rapid interconversion of diazepine ring conformers has also been observed in the structurally related dibenzodiazepine, clozapine and is attributed to the low activation energy for inversion. Petcher, T. J.; Weber, H.-P. J. Chem. Soc., Perkin Trans. 2 1976, 1415-1420.
    • (1976) J. Chem. Soc., Perkin Trans. 2 , pp. 1415-1420
    • Petcher, T.J.1    Weber, H.-P.2
  • 42
    • 0344324773 scopus 로고    scopus 로고
    • note
    • 2 hemisolvate), for which X-ray structures have been determined, each feature the olanzapine dimer.
  • 43
    • 0345187264 scopus 로고    scopus 로고
    • note
    • Refcodes for retrieved structures: CIJMIR, HIFRET, NDNCLH01, NDNHCL01, NDNHCL10, and YUYMUA.
  • 44
    • 0345619354 scopus 로고    scopus 로고
    • note
    • The energetically equivalent mirror image of conformer A was also obtained.
  • 45
    • 0026600109 scopus 로고
    • Analysis of hydrogen-bonding patterns in small peptides has previously revealed that water most frequently donates two hydrogen bonds and accepts one. The criteria for hydrogen bonding outlined by Görbitz and Etter were used to establish the hydrogen-bonding topology in the olanzapine dihydrates. Görbitz, C. H.; Etter, M. C. Int. J. Peptide Protein Res. 1992, 39, 93-110.
    • (1992) Int. J. Peptide Protein Res. , vol.39 , pp. 93-110
    • Görbitz, C.H.1    Etter, M.C.2
  • 46
    • 0344756920 scopus 로고    scopus 로고
    • note
    • Because the water hydrogens were not located in the crystal structure determinations, nonbonded contacts to the waters of crystallization were identified by carefully examining heavy atom distances, with consideration given to hydrogen-bond angles.
  • 49
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    • 15N resonance will shift to higher or lower frequencies, respectively. Naito, A.; Tuzi, S.; Saito, H. Eur. J. Biochem. 1994, 224, 729-734.
    • (1994) Eur. J. Biochem. , vol.224 , pp. 729-734
    • Naito, A.1    Tuzi, S.2    Saito, H.3
  • 53
    • 0344324772 scopus 로고    scopus 로고
    • note
    • 3, respectively, were calculated.
  • 56
    • 0344756919 scopus 로고    scopus 로고
    • note
    • There are numerous examples of highly studied pharmaceutical compounds (aspirin (ACSALA01), ibuprofen (IBPRAC), and fluoxetine HCl (FUDCOW) - the active ingredient in Prozac, to name a few) that, to date, are monomorphic.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.