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Volumn 7, Issue SUPPL. 4, 2010, Pages

A review of nanoparticle functionality and toxicity on the central nervous system

Author keywords

Central nervous system; Functionality; Nanoparticles; Toxicity

Indexed keywords

DRUG DOSAGE; EPOXY RESINS; LEACHING; METAL IONS; RESINS; SILVER OXIDES; TOXICITY;

EID: 77955739920     PISSN: 17425689     EISSN: 17425662     Source Type: Journal    
DOI: 10.1098/rsif.2010.0158.focus     Document Type: Review
Times cited : (225)

References (54)
  • 1
    • 36549018050 scopus 로고    scopus 로고
    • Potential impact of nanotechnology on the control of infectious diseases
    • doi:10.1016/j.trstmh.2007.07.003
    • Allaker, R. P. & Ren, G. 2008 Potential impact of nanotechnology on the control of infectious diseases. Trans. R. Soc. Trop. Med. Hygiene 102, 1-2. (doi:10.1016/j.trstmh.2007.07.003)
    • (2008) Trans. R. Soc. Trop. Med. Hygiene , vol.102 , pp. 1-2
    • Allaker, R.P.1    Ren, G.2
  • 2
    • 36048937333 scopus 로고    scopus 로고
    • Effects of nanoparticles on the adhesion and cell viability on astrocytes
    • doi:10.1007/s12011-007-0067-z
    • Au, C., Mutkus, L., Dobson, A., Riffle, J., Lalli, J. & Aschner, M. 2007 Effects of nanoparticles on the adhesion and cell viability on astrocytes. Biol. Trace Elem. Res. 120, 248-256. (doi:10.1007/s12011-007-0067-z)
    • (2007) Biol. Trace Elem. Res. , vol.120 , pp. 248-256
    • Au, C.1    Mutkus, L.2    Dobson, A.3    Riffle, J.4    Lalli, J.5    Aschner, M.6
  • 3
    • 67650979228 scopus 로고    scopus 로고
    • Effects of carbon nanotubes on primary neurons and glial cells
    • doi:10.1016/j.neuro.2009.05.005
    • Belyanskaya, L., Weigel, S., Hirsch, C., Tobler, U., Krug, H. F. & Wick, P. 2009 Effects of carbon nanotubes on primary neurons and glial cells. Neurotoxicology 30, 702-711. (doi:10.1016/j.neuro.2009.05.005)
    • (2009) Neurotoxicology , vol.30 , pp. 702-711
    • Belyanskaya, L.1    Weigel, S.2    Hirsch, C.3    Tobler, U.4    Krug, H.F.5    Wick, P.6
  • 4
    • 0034891405 scopus 로고    scopus 로고
    • Transport of nanoparticles across the rat nasal mucosa
    • doi:10.3109/10611860108997935
    • Brooking, J., Davis, S. S. & Illum, L. 2001 Transport of nanoparticles across the rat nasal mucosa. J. Drug Targeting 9, 267-279. (doi:10.3109/10611860108997935)
    • (2001) J. Drug Targeting , vol.9 , pp. 267-279
    • Brooking, J.1    Davis, S.S.2    Illum, L.3
  • 5
    • 35348879232 scopus 로고    scopus 로고
    • Cytotoxic effects of nanoparticles assessed in Vitro and in Vivo
    • Cha, K. E. & Myung, H. 2007 Cytotoxic effects of nanoparticles assessed in vitro and in vivo. J. Microbial Biotechnol. 17, 1573-1578. (Pubitemid 47577761)
    • (2007) Journal of Microbiology and Biotechnology , vol.17 , Issue.9 , pp. 1573-1578
    • Cha, K.E.1    Myung, H.2
  • 6
    • 52449097520 scopus 로고    scopus 로고
    • Comparison of acute responses of mice livers to short-term exposure to nano-sized or micro-sized silver particles
    • doi:10.1007/s10529-008-9786-2
    • Cha, K., Hong, H. W., Choi, Y. G., Lee, M. J., Park, J. H., Chae, H. K., Ryu, G. & Myung, H. 2008 Comparison of acute responses of mice livers to short-term exposure to nano-sized or micro-sized silver particles. Biotechnol. Lett. 30, 1893-1899. (doi:10.1007/s10529-008-9786-2)
    • (2008) Biotechnol. Lett. , vol.30 , pp. 1893-1899
    • Cha, K.1    Hong, H.W.2    Choi, Y.G.3    Lee, M.J.4    Park, J.H.5    Chae, H.K.6    Ryu, G.7    Myung, H.8
  • 7
    • 33746866368 scopus 로고    scopus 로고
    • Effect of silver nanoparticle dressing on second degree burn wound
    • Chen, J., Han, C. M., Lin, X. W., Tang, Z. J. & Su, S. J. 2006 Effect of silver nanoparticle dressing on second degree burn wound. Zhonghua Wai Ke Za Zhi 44, 50-52.
    • (2006) Zhonghua Wai Ke Za Zhi , vol.44 , pp. 50-52
    • Chen, J.1    Han, C.M.2    Lin, X.W.3    Tang, Z.J.4    Su, S.J.5
  • 8
    • 4544273482 scopus 로고    scopus 로고
    • Preparation and radiolabeling of human serum albumin (HSA)-coated magnetite nanoparticles for magnetically targeted therapy
    • doi:10.1016/j.apradiso.2004.03.114
    • Chunfu, Z., Jinquan, C., Duanzhi, Y., Yongxian, W., Yanlin, F. & Jiaju, T. 2004 Preparation and radiolabeling of human serum albumin (HSA)-coated magnetite nanoparticles for magnetically targeted therapy. Appl. Radiat. Isot. 61, 1255-1259. (doi:10.1016/j.apradiso.2004.03.114)
    • (2004) Appl. Radiat. Isot. , vol.61 , pp. 1255-1259
    • Chunfu, Z.1    Jinquan, C.2    Duanzhi, Y.3    Yongxian, W.4    Yanlin, F.5    Jiaju, T.6
  • 9
    • 0037377537 scopus 로고    scopus 로고
    • Altered states: The clinical effects of ecstasy
    • doi:10.1016/S0163-7258(03)00003-2
    • Cole, J. C. & Sumnall, H. R. 2003 Altered states: the clinical effects of ecstasy. Pharmacol. Ther. 98, 35-58. (doi:10.1016/S0163-7258(03) 00003-2)
    • (2003) Pharmacol. Ther. , vol.98 , pp. 35-58
    • Cole, J.C.1    Sumnall, H.R.2
  • 10
    • 61349139614 scopus 로고    scopus 로고
    • Drug delivery and nanoparticles: Applications and hazards
    • De Jong, W. H. & Borm, P. J. 2008 Drug delivery and nanoparticles: applications and hazards. Int. J. Nanomed. 3, 133-149.
    • (2008) Int. J. Nanomed. , vol.3 , pp. 133-149
    • De Jong, W.H.1    Borm, P.J.2
  • 11
    • 3543010195 scopus 로고    scopus 로고
    • Detection of micro- and nano-sized biocompatible particles in the blood
    • doi:10.1023/B:JMSM.0000021122.49966.6d
    • Gatti, A. M., Montanari, S., Monari, E., Gambarelli, A., Capitani, F. & Parisini, B. 2004 Detection of micro- and nano-sized biocompatible particles in the blood. J. Mater. Sci. Mater. Med. 15, 469-472. (doi:10.1023/B:JMSM.0000021122.49966.6d)
    • (2004) J. Mater. Sci. Mater. Med. , vol.15 , pp. 469-472
    • Gatti, A.M.1    Montanari, S.2    Monari, E.3    Gambarelli, A.4    Capitani, F.5    Parisini, B.6
  • 12
    • 37349043190 scopus 로고    scopus 로고
    • Voltage-gated sodium channels Nav1.1, Nav1.3 and β1 subunit were up-regulated in the hippocampus of spontaneously epileptic rat
    • doi:10.1016/j.brainresbull.2007.10.005
    • Guo, F., Yu, N., Cai, J. Q., Quinn, T., Zong, Z. H., Zeng, Y. J. & Hao, L. Y. 2008 Voltage-gated sodium channels Nav1.1, Nav1.3 and β1 subunit were up-regulated in the hippocampus of spontaneously epileptic rat. Brain Res. Bull. 75, 179-187. (doi:10.1016/j.brainresbull.2007.10.005)
    • (2008) Brain Res. Bull. , vol.75 , pp. 179-187
    • Guo, F.1    Yu, N.2    Cai, J.Q.3    Quinn, T.4    Zong, Z.H.5    Zeng, Y.J.6    Hao, L.Y.7
  • 13
    • 13644259464 scopus 로고    scopus 로고
    • Nanoparticles - Known and unknown health risks
    • doi:10.1186/1477-3155-2-12
    • Hoet, P. H., Bruske-Hohlfeld, I. & Salata, O. V. 2004 Nanoparticles - known and unknown health risks. J. Nanobiotechnol. 2, 12. (doi:10.1186/1477- 3155-2-12)
    • (2004) J. Nanobiotechnol. , vol.2 , pp. 12
    • Hoet, P.H.1    Bruske-Hohlfeld, I.2    Salata, O.V.3
  • 14
    • 33745775422 scopus 로고    scopus 로고
    • The interaction of manganese nanoparticles with PC-12 cells induces dopamine depletion
    • doi:10.1093/toxsci/kfl020
    • Hussain, S. M., Javorina, A. K., Schrand, A. M., Duhart, H. M., Ali, S. F. & Schlager, J. J. 2006a The interaction of manganese nanoparticles with PC-12 cells induces dopamine depletion. Toxicol. Sci. 92, 456-463. (doi:10.1093/toxsci/kfl020)
    • (2006) Toxicol. Sci. , vol.92 , pp. 456-463
    • Hussain, S.M.1    Javorina, A.K.2    Schrand, A.M.3    Duhart, H.M.4    Ali, S.F.5    Schlager, J.J.6
  • 15
    • 33745775422 scopus 로고    scopus 로고
    • The interaction of manganese nanoparticles with PC-12 cells induces dopamine depletion
    • doi:10.1093/toxsci/kfl020
    • Hussain, S. M., Javorina, A. K., Schrand, A. M., Duhart, H. M., Ali, S. F. & Schlager, J. J. 2006b The interaction of manganese nanoparticles with PC-12 cells induces dopamine depletion. Toxicol. Sci. 92, 456-463. (doi:10.1093/toxsci/kfl020)
    • (2006) Toxicol. Sci. , vol.92 , pp. 456-463
    • Hussain, S.M.1    Javorina, A.K.2    Schrand, A.M.3    Duhart, H.M.4    Ali, S.F.5    Schlager, J.J.6
  • 16
    • 29544433253 scopus 로고    scopus 로고
    • Toxicity and tissue distribution of magnetic nanoparticles in mice
    • doi:10.1093/toxsci/kfj027
    • Kim, J. S. et al. 2006 Toxicity and tissue distribution of magnetic nanoparticles in mice. Toxicol. Sci. 89, 338-347. (doi:10.1093/toxsci/kfj027)
    • (2006) Toxicol. Sci. , vol.89 , pp. 338-347
    • Kim, J.S.1
  • 17
    • 63149166892 scopus 로고    scopus 로고
    • Antifungal activity and mode of action of silver nano-particles on Candida albicans
    • doi:10.1007/s10534-008-9159-2
    • Kim, K. J., Sung, W. S., Suh, B. K., Moon, S. K., Choi, J. S., Kim, J. G. & Lee, D. G. 2009 Antifungal activity and mode of action of silver nano-particles on Candida albicans. Biometals 22, 235-242. (doi:10.1007/s10534- 008-9159-2)
    • (2009) Biometals , vol.22 , pp. 235-242
    • Kim, K.J.1    Sung, W.S.2    Suh, B.K.3    Moon, S.K.4    Choi, J.S.5    Kim, J.G.6    Lee, D.G.7
  • 19
    • 77951933010 scopus 로고    scopus 로고
    • NanoBioInterface: A multidisciplinary challenge
    • doi:10.1098/rsif.2009.0489.focus
    • Kirkpatrick, C. J. & Bonfield, W. 2010 NanoBioInterface: a multidisciplinary challenge. J. R. Soc. Interface 7, S1-S4. (doi:10.1098/rsif. 2009.0489.focus)
    • (2010) J. R. Soc. Interface , vol.7
    • Kirkpatrick, C.J.1    Bonfield, W.2
  • 20
    • 4944234013 scopus 로고    scopus 로고
    • Laboratory assessment of the mobility of nanomaterials in porous media
    • doi:10.1021/es0352303
    • Lecoanet, H. F., Bottero, J. Y. &Wiesner, M. R. 2004 Laboratory assessment of the mobility of nanomaterials in porous media. Environ. Sci. Technol. 38, 5164-5169. (doi:10.1021/es0352303)
    • (2004) Environ. Sci. Technol. , vol.38 , pp. 5164-5169
    • Lecoanet, H.F.1    Bottero, J.Y.2    Wiesner, M.R.3
  • 21
    • 70349203669 scopus 로고    scopus 로고
    • Action potential changes associated with the inhibitory effects on voltage-gated sodium current of hippocampal CA1 neurons by silver nanoparticles
    • doi:10.1016/j.tox.2009.08.005
    • Liu, Z., Ren, G., Zhang, T. & Yang, Z. 2009 Action potential changes associated with the inhibitory effects on voltage-gated sodium current of hippocampal CA1 neurons by silver nanoparticles. Toxicology 264, 179-184. (doi:10.1016/j.tox.2009.08.005)
    • (2009) Toxicology , vol.264 , pp. 179-184
    • Liu, Z.1    Ren, G.2    Zhang, T.3    Yang, Z.4
  • 22
    • 71849101617 scopus 로고    scopus 로고
    • Oxidative stress and apoptosis induced by nanosized titanium dioxide in PC12 cells
    • doi:10.1016/j.tox.2009.11.012
    • Liu, S., Xu, L., Zhang, T., Ren, G. & Yang, Z. 2010 Oxidative stress and apoptosis induced by nanosized titanium dioxide in PC12 cells. Toxicology 267, 172-177. (doi:10.1016/j.tox.2009.11.012)
    • (2010) Toxicology , vol.267 , pp. 172-177
    • Liu, S.1    Xu, L.2    Zhang, T.3    Ren, G.4    Yang, Z.5
  • 23
    • 33746255334 scopus 로고    scopus 로고
    • Titanium dioxide (P25) produces reactive oxygen species in immortalized brain microglia (BV2): Implications for nanoparticle neurotoxicity
    • doi:10.1021/es060589n
    • Long, T. C., Saleh, N., Tilton, R. D., Lowry, G. V. & Veronesi, B. 2006 Titanium dioxide (P25) produces reactive oxygen species in immortalized brain microglia (BV2): implications for nanoparticle neurotoxicity. Environ. Sci. Technol. 40, 4346-4352. (doi:10.1021/es060589n)
    • (2006) Environ. Sci. Technol. , vol.40 , pp. 4346-4352
    • Long, T.C.1    Saleh, N.2    Tilton, R.D.3    Lowry, G.V.4    Veronesi, B.5
  • 24
    • 44649203035 scopus 로고    scopus 로고
    • Construction, application and biosafety of silver nanocrystalline chitosan wound dressing
    • doi:10.1016/j.burns.2007.08.020
    • Lu, S., Gao, W. & Gu, H. Y. 2008 Construction, application and biosafety of silver nanocrystalline chitosan wound dressing. Burns 34, 623-628. (doi:10.1016/j.burns.2007.08.020)
    • (2008) Burns , vol.34 , pp. 623-628
    • Lu, S.1    Gao, W.2    Gu, H.Y.3
  • 25
    • 23644439941 scopus 로고    scopus 로고
    • Sodium channel mutations in epilepsy and other neurological disorders
    • doi:10.1172/JCI25466
    • Meisler, M. H. & Kearney, J. A. 2005 Sodium channel mutations in epilepsy and other neurological disorders. J. Clin. Invest. 115, 2010-2017. (doi:10.1172/JCI25466)
    • (2005) J. Clin. Invest. , vol.115 , pp. 2010-2017
    • Meisler, M.H.1    Kearney, J.A.2
  • 26
    • 0035380036 scopus 로고    scopus 로고
    • Synthetic bone graft substitutes
    • doi:10.1046/j.1440-1622.2001.02128.x
    • Moore, W. R., Graves, S. E. & Bain, G. I. 2001 Synthetic bone graft substitutes. ANZ J. Surg. 71, 354-361. (doi:10.1046/j.1440-1622.2001.02128.x)
    • (2001) ANZ J. Surg. , vol.71 , pp. 354-361
    • Moore, W.R.1    Graves, S.E.2    Bain, G.I.3
  • 27
    • 60249083615 scopus 로고    scopus 로고
    • Targeted nanomedicines: Effective treatment modalities for cancer, AIDS and brain disorders
    • doi:10.2217/17435889.4.1.105
    • Muthu, M. S. & Singh, S. 2009 Targeted nanomedicines: effective treatment modalities for cancer, AIDS and brain disorders. Nanomedicine (Lond.) 4, 105-118. (doi:10.2217/17435889.4.1.105)
    • (2009) Nanomedicine (Lond.) , vol.4 , pp. 105-118
    • Muthu, M.S.1    Singh, S.2
  • 28
    • 3543146722 scopus 로고    scopus 로고
    • Manufactured nanomaterials (fullerenes, C60) induce oxidative stress in the brain of juvenile largemouth bass
    • Oberdörster, E. 2004 Manufactured nanomaterials (fullerenes, C60) induce oxidative stress in the brain of juvenile largemouth bass. Environ. Health Perspect. 112, 1058-1062.
    • (2004) Environ. Health Perspect. , vol.112 , pp. 1058-1062
    • Oberdörster, E.1
  • 29
    • 33845214358 scopus 로고    scopus 로고
    • Review: Principles for characterizing the potential human health effects from exposure to nanomaterials elements of a screening strategy
    • ILSI Research Foundation/Risk Science Institute Nanomaterial Toxicity Screening Working Group doi:10.1186/1743-8977-2-8
    • Oberdörster, G. et al. & ILSI Research Foundation/Risk Science Institute Nanomaterial Toxicity Screening Working Group. 2005 Review: principles for characterizing the potential human health effects from exposure to nanomaterials elements of a screening strategy. Part. Fibre Toxicol. 2, 8. (doi:10.1186/1743-8977-2-8)
    • (2005) Part. Fibre Toxicol. , vol.2 , pp. 8
    • Oberdörster, G.1
  • 30
    • 56549119606 scopus 로고    scopus 로고
    • Silver or silver nanoparticles: A hazardous threat to the environment and human health?
    • Panyala, N. R., Pena-Mendez, E. M. & Havel, J. 2008 Silver or silver nanoparticles: a hazardous threat to the environment and human health? J. Appl. Biomed. 6, 117-129.
    • (2008) J. Appl. Biomed. , vol.6 , pp. 117-129
    • Panyala, N.R.1    Pena-Mendez, E.M.2    Havel, J.3
  • 32
    • 27744473488 scopus 로고    scopus 로고
    • Relative risk analysis of several manufactured nanomaterials: An insurance industry context
    • doi:10.1021/es0506509
    • Robichaud, C. O., Tanzil, D., Weilenmann, U. & Wiesner, M. R. 2005 Relative risk analysis of several manufactured nanomaterials: an insurance industry context. Environ. Sci. Technol. 39, 8985-8994. (doi:10.1021/es0506509)
    • (2005) Environ. Sci. Technol. , vol.39 , pp. 8985-8994
    • Robichaud, C.O.1    Tanzil, D.2    Weilenmann, U.3    Wiesner, M.R.4
  • 33
    • 10444245515 scopus 로고    scopus 로고
    • Royal Academy of Engineering BMRB Social Research Report for the Royal Society and Royal Academy of Engineering Nanotechnology Working Group, BMRB/45/101-666. London, UK: BMRB Social Research
    • Royal Academy of Engineering 2004 Nanotechnology: views of the general public. Quantitative and qualitative research carried out as part of the Nanotechnology Study. BMRB Social Research Report for the Royal Society and Royal Academy of Engineering Nanotechnology Working Group, BMRB/45/101-666. London, UK: BMRB Social Research.
    • (2004) Nanotechnology: Views of the General Public. Quantitative and Qualitative Research Carried out As Part of the Nanotechnology Study
  • 34
    • 0020618017 scopus 로고
    • Localization of exogenous silver in brain and spinal cord of silver exposed rats
    • doi:10.1007/BF00685352
    • Rungby, J. & Danscher, G. 1983 Localization of exogenous silver in brain and spinal cord of silver exposed rats. Acta Neuropathol. 60, 92-98. (doi:10.1007/BF00685352)
    • (1983) Acta Neuropathol. , vol.60 , pp. 92-98
    • Rungby, J.1    Danscher, G.2
  • 35
    • 60749134708 scopus 로고    scopus 로고
    • Effective transvascular delivery of nanoparticles across the blood-brain tumor barrier into malignant glioma cells
    • doi:10.1186/1479-5876-6-80
    • Sarin, H. et al. 2008 Effective transvascular delivery of nanoparticles across the blood-brain tumor barrier into malignant glioma cells. J. Transl. Med. 6, 80. (doi:10.1186/1479-5876-6-80)
    • (2008) J. Transl. Med. , vol.6 , pp. 80
    • Sarin, H.1
  • 36
    • 68549095935 scopus 로고    scopus 로고
    • Tissue distribution of 20 nm, 100 nm and 1000 nm fluorescent polystyrene latex nanospheres following acute systemic or acute and repeat airway exposure in the rat
    • doi:10.1016/j.tox.2009.07.002
    • Sarlo, K. et al. 2009 Tissue distribution of 20 nm, 100 nm and 1000 nm fluorescent polystyrene latex nanospheres following acute systemic or acute and repeat airway exposure in the rat. Toxicology 263, 117-126. (doi:10.1016/j.tox. 2009.07.002)
    • (2009) Toxicology , vol.263 , pp. 117-126
    • Sarlo, K.1
  • 37
    • 77951903853 scopus 로고    scopus 로고
    • Nanoparticles, human health hazard and regulation
    • doi:10.1098/rsif.2009.0252.focus
    • Seaton, A., Tran, L., Aitken, R. & Donaldson, K. 2010 Nanoparticles, human health hazard and regulation. J. R. Soc. Interface 7, S119-S129. (doi:10.1098/rsif.2009.0252.focus)
    • (2010) J. R. Soc. Interface , vol.7
    • Seaton, A.1    Tran, L.2    Aitken, R.3    Donaldson, K.4
  • 38
    • 34249887202 scopus 로고    scopus 로고
    • DNA enables nanoscale control of the structure of matter
    • Seeman, N. C. 2006 DNA enables nanoscale control of the structure of matter. Q. Rev. Biophys. 6, 1-9.
    • (2006) Q. Rev. Biophys. , vol.6 , pp. 1-9
    • Seeman, N.C.1
  • 39
    • 0025643806 scopus 로고
    • Evaluation of health risks by airborne particulates from in vitro cyto- and genotoxicity testing on human and rodent tissue culture cells: A longitudinal study from 1975 until now
    • doi:10.1016/0021-8502(90)90290-E
    • Seemayer, N. H., Hadnagy, W. & Tomingas, T. 1990 Evaluation of health risks by airborne particulates from in vitro cyto- and genotoxicity testing on human and rodent tissue culture cells: a longitudinal study from 1975 until now. J. Aerosol. Sci. 21(Suppl. 1), 501-504. (doi:10.1016/0021-8502(90)90290-E)
    • (1990) J. Aerosol. Sci. , vol.21 , Issue.SUPPL. 1 , pp. 501-504
    • Seemayer, N.H.1    Hadnagy, W.2    Tomingas, T.3
  • 40
    • 17344367164 scopus 로고    scopus 로고
    • GLUT-1 deficiency syndrome caused by haploinsufficiency of the blood-brain barrier hexose carrier
    • doi:10.1038/ng0298-188
    • Seidner, G. et al. 1998 GLUT-1 deficiency syndrome caused by haploinsufficiency of the blood-brain barrier hexose carrier. Nat. Genet. 18, 188-191. (doi:10.1038/ng0298-188)
    • (1998) Nat. Genet. , vol.18 , pp. 188-191
    • Seidner, G.1
  • 41
    • 34447628891 scopus 로고    scopus 로고
    • Nanoparticles aggravate heat stress induced cognitive deficits, blood-brain barrier disruption, edema formation and brain pathology
    • doi:10.1016/S0079-6123(06)62013-X
    • Sharma, H. S. & Sharma, A. 2007 Nanoparticles aggravate heat stress induced cognitive deficits, blood-brain barrier disruption, edema formation and brain pathology. Prog. Brain Res. 162, 245-273. (doi:10.1016/S0079-6123(06) 62013-X)
    • (2007) Prog. Brain Res. , vol.162 , pp. 245-273
    • Sharma, H.S.1    Sharma, A.2
  • 42
    • 78649361273 scopus 로고    scopus 로고
    • Influence of nanoparticles on blood-brain barrier permeability and brain edema formation in rats
    • doi:10.1007/978-3-211-98811-4-65
    • Sharma, H. S., Hussain, S., Schlager, J., Ali, S. F. & Sharma, A. 2010 Influence of nanoparticles on blood-brain barrier permeability and brain edema formation in rats. Acta Neurochir. Suppl. 106, 359-364. (doi:10.1007/978-3-211-98811-4-65)
    • (2010) Acta Neurochir. Suppl. , vol.106 , pp. 359-364
    • Sharma, H.S.1    Hussain, S.2    Schlager, J.3    Ali, S.F.4    Sharma, A.5
  • 43
    • 68949212357 scopus 로고    scopus 로고
    • Maternal exposure to nanoparticulate titanium dioxide during the prenatal period alters gene expression related to brain development in the mouse
    • doi:10.1186/1743-8977-6-20
    • Shimizu, M., Tainaka, H., Oba, T., Mizuo, K., Umezawa, M. & Takeda, K. 2009 Maternal exposure to nanoparticulate titanium dioxide during the prenatal period alters gene expression related to brain development in the mouse. Part. Fibre Toxicol. 6, 20. (doi:10.1186/1743-8977-6-20)
    • (2009) Part. Fibre Toxicol. , vol.6 , pp. 20
    • Shimizu, M.1    Tainaka, H.2    Oba, T.3    Mizuo, K.4    Umezawa, M.5    Takeda, K.6
  • 44
    • 35748933519 scopus 로고    scopus 로고
    • The effects of nano-silver on the proliferation and cytokine expression by peripheral blood mononuclear cells
    • doi:10.1016/j.intimp.2007.08.025
    • Shin, S. H., Ye, M. K., Kim, H. S. & Kang, H. S. 2007 The effects of nano-silver on the proliferation and cytokine expression by peripheral blood mononuclear cells. Int. Immunopharmacol. 7, 1813-1818. (doi:10.1016/j.intimp. 2007.08.025)
    • (2007) Int. Immunopharmacol. , vol.7 , pp. 1813-1818
    • Shin, S.H.1    Ye, M.K.2    Kim, H.S.3    Kang, H.S.4
  • 45
    • 58149154662 scopus 로고    scopus 로고
    • Nano-silver-modified PQC/DNA biosensor for detecting E. coli in environmental water
    • doi:10.1016/j.bios.2008.08.008
    • Sun, H., Choy, T. S., Zhu, D. R., Yam, W. C. & Fung, Y. S. 2009 Nano-silver-modified PQC/DNA biosensor for detecting E. coli in environmental water. Biosens. Bioelectron. 24, 1405-1410. (doi:10.1016/j.bios.2008.08.008)
    • (2009) Biosens. Bioelectron. , vol.24 , pp. 1405-1410
    • Sun, H.1    Choy, T.S.2    Zhu, D.R.3    Yam, W.C.4    Fung, Y.S.5
  • 46
    • 46749130939 scopus 로고    scopus 로고
    • Unmodified CdSe quantum dots induce elevation of cytoplasmic calcium levels and impairment of functional properties of sodium channels in rat primary cultured hippocampal neurons
    • doi:10.1289/ehp.11225
    • Tang, M. et al. 2008 Unmodified CdSe quantum dots induce elevation of cytoplasmic calcium levels and impairment of functional properties of sodium channels in rat primary cultured hippocampal neurons. Environ. Health Perspect. 116, 915-922. (doi:10.1289/ehp.11225)
    • (2008) Environ. Health Perspect. , vol.116 , pp. 915-922
    • Tang, M.1
  • 47
    • 70350418852 scopus 로고    scopus 로고
    • Distribution, translocation and accumulation of silver nanoparticles in rats
    • doi:10.1166/jnn.2009.1269
    • Tang, J., Xiong, L., Wang, S., Wang, J., Liu, L., Li, J., Yuan, F. & Xi, T. 2009 Distribution, translocation and accumulation of silver nanoparticles in rats. J. Nanosci. Nanotechnol. 9, 4924-4932. (doi:10.1166/jnn.2009.1269)
    • (2009) J. Nanosci. Nanotechnol. , vol.9 , pp. 4924-4932
    • Tang, J.1    Xiong, L.2    Wang, S.3    Wang, J.4    Liu, L.5    Li, J.6    Yuan, F.7    Xi, T.8
  • 48
    • 39649098687 scopus 로고    scopus 로고
    • The role of electrosprayed nanoapatites in guiding osteoblast behaviour
    • doi:10.1016/j.biomaterials.2008.01.007
    • Thian, E. S. et al. 2008 The role of electrosprayed nanoapatites in guiding osteoblast behaviour. Biomaterials 29, 1833-1843. (doi:10.1016/j. biomaterials.2008.01.007)
    • (2008) Biomaterials , vol.29 , pp. 1833-1843
    • Thian, E.S.1
  • 49
    • 56549115351 scopus 로고    scopus 로고
    • Potential neurological lesion after nasal instillation of TiO(2) nanoparticles in the anatase and rutile crystal phases
    • doi:10. 1016/j.toxlet.2008.10.001
    • Wang, J. et al. 2008 Potential neurological lesion after nasal instillation of TiO(2) nanoparticles in the anatase and rutile crystal phases. Toxicol. Lett. 183, 72-80. (doi:10. 1016/j.toxlet.2008.10.001)
    • (2008) Toxicol. Lett. , vol.183 , pp. 72-80
    • Wang, J.1
  • 50
    • 71249090339 scopus 로고    scopus 로고
    • Expression changes of dopaminergic system-related genes in PC12 cells induced by manganese, silver, or copper nanoparticles
    • doi:10.1016/j.neuro.2009.09.005
    • Wang, J., Rahman, M. F., Duhart, H. M., Newport, G. D., Patterson, T. A., Murdock, R. C., Hussain, S. M., Schlager, J. J. & Ali, S. F. 2009 Expression changes of dopaminergic system-related genes in PC12 cells induced by manganese, silver, or copper nanoparticles. Neurotoxicology 30, 926-933. (doi:10.1016/j.neuro.2009.09.005)
    • (2009) Neurotoxicology , vol.30 , pp. 926-933
    • Wang, J.1    Rahman, M.F.2    Duhart, H.M.3    Newport, G.D.4    Patterson, T.A.5    Murdock, R.C.6    Hussain, S.M.7    Schlager, J.J.8    Ali, S.F.9
  • 51
    • 0942269167 scopus 로고    scopus 로고
    • Comparative pulmonary toxicity assessment of single-wall carbon nanotubes in rats
    • doi:10.1093/toxsci/kfg228
    • Warheit, D. B., Laurence, B. R., Reed, K. L., Roach, D. H., Reynolds, G. A. &Webb, T. R. 2004 Comparative pulmonary toxicity assessment of single-wall carbon nanotubes in rats. Toxicol. Sci. 77, 117-125. (doi:10.1093/toxsci/kfg228)
    • (2004) Toxicol. Sci. , vol.77 , pp. 117-125
    • Warheit, D.B.1    Laurence, B.R.2    Reed, K.L.3    Roach, D.H.4    Reynolds, G.A.5    Webb, T.R.6
  • 52
    • 66849119252 scopus 로고    scopus 로고
    • In vitro study on influence of nano particles of CuO on CA1 pyramidal neurons of rat hippocampus potassium currents
    • doi:10.1002/tox.20418
    • Xu, L. J., Zhao, J. X., Zhang, T., Ren, G. G. & Yang, Z. 2009 In vitro study on influence of nano particles of CuO on CA1 pyramidal neurons of rat hippocampus potassium currents. Environ. Toxicol. 24, 211-217. (doi:10.1002/tox.20418)
    • (2009) Environ. Toxicol. , vol.24 , pp. 211-217
    • Xu, L.J.1    Zhao, J.X.2    Zhang, T.3    Ren, G.G.4    Yang, Z.5
  • 53
    • 61849159858 scopus 로고    scopus 로고
    • Influences of nanoparticle zinc oxide on acutely isolated rat hippocampal CA3 pyramidal neurons
    • doi:10.1016/j.neuro.2008.12.005
    • Zhao, J., Xu, L., Zhang, T., Ren, G. & Yang, Z. 2009 Influences of nanoparticle zinc oxide on acutely isolated rat hippocampal CA3 pyramidal neurons. Neurotoxicology 30, 220-230. (doi:10.1016/j.neuro.2008.12.005)
    • (2009) Neurotoxicology , vol.30 , pp. 220-230
    • Zhao, J.1    Xu, L.2    Zhang, T.3    Ren, G.4    Yang, Z.5
  • 54
    • 0033963568 scopus 로고    scopus 로고
    • Blockade of U50488H on sodium currents in acutely isolated mice hippocampal CA3 pyramidal neurons
    • doi:10.1016/S0006-8993(99)02360-4
    • Zou, B., Chen, Y., Wu, C. & Zhou, P. 2000 Blockade of U50488H on sodium currents in acutely isolated mice hippocampal CA3 pyramidal neurons. Brain Res. 855, 132-136. (doi:10.1016/S0006-8993(99)02360-4)
    • (2000) Brain Res. , vol.855 , pp. 132-136
    • Zou, B.1    Chen, Y.2    Wu, C.3    Zhou, P.4


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