Protein tyrosine phosphatase SHP2 regulates TGF-β1 production in airway epithelia and asthmatic airway remodeling in mice

Allergy: European Journal of Allergy and Clinical Immunology

Volumn 67, Issue 12, 2012, Pages 1547-1556

  Qin, X J ^a   Zhang, G S ^a   Zhang, X ^a   Qiu, Z W ^a   Wang, P L ^a   Li, Y W ^a   Li, W ^a   Xie, Q M ^a   Ke, Y H ^a   Lee, J J ^c   Shen, H H ^a,b  

^a ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b State Key Laboratory of Respiratory Disease   (China)

^c MAYO GRADUATE SCHOOL   (United States)

Author keywords

airway epithelia; asthma; mice; protein tyrosine phosphatase SHP2; remodeling

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; PROTEIN TYROSINE PHOSPHATASE SHP 2; TRANSFORMING GROWTH FACTOR BETA1;

AIRWAY REMODELING; ANIMAL EXPERIMENT; ARTICLE; ASTHMA; CELL INFILTRATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; FEMALE; GENE DELETION; GENE EXPRESSION; GENE INACTIVATION; IN VITRO STUDY; INHALATION TEST; LUNG ALVEOLUS EPITHELIUM; LUNG FIBROSIS; LUNG FLUID; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; WILD TYPE;

AIRWAY REMODELING; ALLERGENS; ANIMALS; ASTHMA; COLLAGEN; DISEASE MODELS, ANIMAL; FEMALE; FIBROBLASTS; GENE EXPRESSION REGULATION; GENE TARGETING; HUMANS; LUNG; MALE; MICE; MICE, KNOCKOUT; MYOFIBROBLASTS; OVALBUMIN; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 11; RESPIRATORY MUCOSA; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84869496367     PISSN: 01054538     EISSN: 13989995     Source Type: Journal    
DOI: 10.1111/all.12048     Document Type: Article

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