-
1
-
-
0037315208
-
Regulation of signaling protein function and trafficking by the hsp90/hsp70-based chaperone machinery
-
W.B. Pratt, and D.O. Toft Regulation of signaling protein function and trafficking by the hsp90/hsp70-based chaperone machinery Exp. Biol. Med. (Maywood) 228 2003 111 133
-
(2003)
Exp. Biol. Med. (Maywood)
, vol.228
, pp. 111-133
-
-
Pratt, W.B.1
Toft, D.O.2
-
2
-
-
33746660802
-
Comparative genomics and evolution of the HSP90 family of genes across all kingdoms of organisms
-
B. Chen, D. Zhong, and A. Monteiro Comparative genomics and evolution of the HSP90 family of genes across all kingdoms of organisms BMC Genomics 7 2006 156
-
(2006)
BMC Genomics
, vol.7
, pp. 156
-
-
Chen, B.1
Zhong, D.2
Monteiro, A.3
-
3
-
-
0032538995
-
In vivo function of Hsp90 is dependent on ATP binding and ATP hydrolysis
-
W.M. Obermann, and H. Sondermann F.U. Hartl In vivo function of Hsp90 is dependent on ATP binding and ATP hydrolysis J. Cell Biol. 143 1998 901 910
-
(1998)
J. Cell Biol.
, vol.143
, pp. 901-910
-
-
Obermann, W.M.1
Sondermann, H.2
Hartl, F.U.3
-
4
-
-
0032541344
-
ATP binding and hydrolysis are essential to the function of the Hsp90 molecular chaperone in vivo
-
B. Panaretou, and C. Prodromou L.H. Pearl ATP binding and hydrolysis are essential to the function of the Hsp90 molecular chaperone in vivo EMBO J. 17 1998 4829 4836
-
(1998)
EMBO J.
, vol.17
, pp. 4829-4836
-
-
Panaretou, B.1
Prodromou, C.2
Pearl, L.H.3
-
5
-
-
33646176246
-
Crystal structure of an Hsp90-nucleotide-p23/Sba1 closed chaperone complex
-
M.M.U. Ali, and S.M. Roe L.H. Pearl Crystal structure of an Hsp90-nucleotide-p23/Sba1 closed chaperone complex Nature 440 2006 1013 1017
-
(2006)
Nature
, vol.440
, pp. 1013-1017
-
-
Ali, M.M.U.1
Roe, S.M.2
Pearl, L.H.3
-
6
-
-
62049084010
-
Spatially and kinetically resolved changes in the conformational dynamics of the Hsp90 chaperone machine
-
C. Graf, and M. Stankiewicz M.P. Mayer Spatially and kinetically resolved changes in the conformational dynamics of the Hsp90 chaperone machine EMBO J. 28 2009 602 613
-
(2009)
EMBO J.
, vol.28
, pp. 602-613
-
-
Graf, C.1
Stankiewicz, M.2
Mayer, M.P.3
-
7
-
-
75149172037
-
Osmolyte-induced conformational changes in the Hsp90 molecular chaperone
-
T.O. Street, and K.A. Krukenberg D.A. Agard Osmolyte-induced conformational changes in the Hsp90 molecular chaperone Protein Sci. 19 2010 57 65
-
(2010)
Protein Sci.
, vol.19
, pp. 57-65
-
-
Street, T.O.1
Krukenberg, K.A.2
Agard, D.A.3
-
8
-
-
84859455527
-
Structure-based model of allostery predicts coupling between distant sites
-
P. Weinkam, J. Pons, and A. Sali Structure-based model of allostery predicts coupling between distant sites Proc. Natl. Acad. Sci. USA 109 2012 4875 4880
-
(2012)
Proc. Natl. Acad. Sci. USA
, vol.109
, pp. 4875-4880
-
-
Weinkam, P.1
Pons, J.2
Sali, A.3
-
9
-
-
38949190032
-
Allosteric effects in the marginally stable von Hippel-Lindau tumor suppressor protein and allostery-based rescue mutant design
-
J. Liu, and R. Nussinov Allosteric effects in the marginally stable von Hippel-Lindau tumor suppressor protein and allostery-based rescue mutant design Proc. Natl. Acad. Sci. USA 105 2008 901 906
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 901-906
-
-
Liu, J.1
Nussinov, R.2
-
10
-
-
70149109136
-
Computation of conformational coupling in allosteric proteins
-
B.A. Kidd, D. Baker, and W.E. Thomas Computation of conformational coupling in allosteric proteins PLOS Comput. Biol. 5 2009 e1000484
-
(2009)
PLOS Comput. Biol.
, vol.5
, pp. 1000484
-
-
Kidd, B.A.1
Baker, D.2
Thomas, W.E.3
-
11
-
-
77955249382
-
Mapping the druggable allosteric space of G-protein coupled receptors: A fragment-based molecular dynamics approach
-
A. Ivetac, and J.A. McCammon Mapping the druggable allosteric space of G-protein coupled receptors: a fragment-based molecular dynamics approach Chem. Biol. Drug Des. 76 2010 201 217
-
(2010)
Chem. Biol. Drug Des.
, vol.76
, pp. 201-217
-
-
Ivetac, A.1
McCammon, J.A.2
-
12
-
-
80053446329
-
Changes in dynamics upon oligomerization regulate substrate binding and allostery in amino acid kinase family members
-
E. Marcos, R. Crehuet, and I. Bahar Changes in dynamics upon oligomerization regulate substrate binding and allostery in amino acid kinase family members PLOS Comput. Biol. 7 2011 e1002201
-
(2011)
PLOS Comput. Biol.
, vol.7
, pp. 1002201
-
-
Marcos, E.1
Crehuet, R.2
Bahar, I.3
-
13
-
-
0242268469
-
Nonlinear elasticity, proteinquakes, and the energy landscapes of functional transitions in proteins
-
O. Miyashita, J.N. Onuchic, and P.G. Wolynes Nonlinear elasticity, proteinquakes, and the energy landscapes of functional transitions in proteins Proc. Natl. Acad. Sci. USA 100 2003 12570 12575
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 12570-12575
-
-
Miyashita, O.1
Onuchic, J.N.2
Wolynes, P.G.3
-
14
-
-
73449144096
-
Dynamic allostery in the methionine repressor revealed by force distribution analysis
-
W. Stacklies, F. Xia, and F. Gräter Dynamic allostery in the methionine repressor revealed by force distribution analysis PLOS Comput. Biol. 5 2009 e1000574
-
(2009)
PLOS Comput. Biol.
, vol.5
, pp. 1000574
-
-
Stacklies, W.1
Xia, F.2
Gräter, F.3
-
15
-
-
45849120595
-
Understanding ligand-based modulation of the Hsp90 molecular chaperone dynamics at atomic resolution
-
G. Colombo, and G. Morra G. Verkhivker Understanding ligand-based modulation of the Hsp90 molecular chaperone dynamics at atomic resolution Proc. Natl. Acad. Sci. USA 105 2008 7976 7981
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 7976-7981
-
-
Colombo, G.1
Morra, G.2
Verkhivker, G.3
-
16
-
-
63549104682
-
Modeling signal propagation mechanisms and ligand-based conformational dynamics of the Hsp90 molecular chaperone full-length dimer
-
G. Morra, G. Verkhivker, and G. Colombo Modeling signal propagation mechanisms and ligand-based conformational dynamics of the Hsp90 molecular chaperone full-length dimer PLOS Comput. Biol. 5 2009 e1000323
-
(2009)
PLOS Comput. Biol.
, vol.5
, pp. 1000323
-
-
Morra, G.1
Verkhivker, G.2
Colombo, G.3
-
17
-
-
84861005184
-
Corresponding functional dynamics across the Hsp90 Chaperone family: Insights from a multiscale analysis of MD simulations
-
G. Morra, and R. Potestio G. Colombo Corresponding functional dynamics across the Hsp90 Chaperone family: insights from a multiscale analysis of MD simulations PLOS Comput. Biol. 8 2012 e1002433
-
(2012)
PLOS Comput. Biol.
, vol.8
, pp. 1002433
-
-
Morra, G.1
Potestio, R.2
Colombo, G.3
-
18
-
-
77953464741
-
Mechanical energy transfer and dissipation in fibrous β-sheet-rich proteins
-
Z. Xu, and M.J. Buehler Mechanical energy transfer and dissipation in fibrous β-sheet-rich proteins Phys. Rev. E Stat. Nonlin. Soft Matter Phys. 81 2010 061910
-
(2010)
Phys. Rev. e Stat. Nonlin. Soft Matter Phys.
, vol.81
, pp. 061910
-
-
Xu, Z.1
Buehler, M.J.2
-
19
-
-
46249092554
-
Gromacs 4: Algorithms for highly efficient, load-balanced, and scalable molecular simulation
-
B. Hess, and C. Kutzner E. Lindahl Gromacs 4: algorithms for highly efficient, load-balanced, and scalable molecular simulation J. Chem. Theory Comput. 4 2008 435 447
-
(2008)
J. Chem. Theory Comput.
, vol.4
, pp. 435-447
-
-
Hess, B.1
Kutzner, C.2
Lindahl, E.3
-
20
-
-
0029912748
-
Development and testing of the opls all-atom force field on conformational energetics and properties of organic liquids
-
W.L. Jorgensen, D.S. Maxwell, and J. Tirado-Rives Development and testing of the opls all-atom force field on conformational energetics and properties of organic liquids J. Am. Chem. Soc. 118 1996 11225 11236
-
(1996)
J. Am. Chem. Soc.
, vol.118
, pp. 11225-11236
-
-
Jorgensen, W.L.1
Maxwell, D.S.2
Tirado-Rives, J.3
-
21
-
-
0038707540
-
Chemometric study of liquid water simulations. I. The parameters of the TIP4P model potential
-
M.Z. Hernandes, J.B.P. da Silva, and R.L. Longo Chemometric study of liquid water simulations. I. The parameters of the TIP4P model potential J. Comput. Chem. 24 2003 973 981
-
(2003)
J. Comput. Chem.
, vol.24
, pp. 973-981
-
-
Hernandes, M.Z.1
Da Silva, J.B.P.2
Longo, R.L.3
-
22
-
-
33750008686
-
Structural analysis of E. coli hsp90 reveals dramatic nucleotide-dependent conformational rearrangements
-
A.K. Shiau, and S.F. Harris D.A. Agard Structural analysis of E. coli hsp90 reveals dramatic nucleotide-dependent conformational rearrangements Cell 127 2006 329 340
-
(2006)
Cell
, vol.127
, pp. 329-340
-
-
Shiau, A.K.1
Harris, S.F.2
Agard, D.A.3
-
23
-
-
0346882663
-
ModLoop: Automated modeling of loops in protein structures
-
A. Fiser, and A. Sali ModLoop: automated modeling of loops in protein structures Bioinformatics 19 2003 2500 2501
-
(2003)
Bioinformatics
, vol.19
, pp. 2500-2501
-
-
Fiser, A.1
Sali, A.2
-
24
-
-
0025398721
-
What if: A molecular modeling and drug design program
-
G. Vriend What if: A molecular modeling and drug design program J. Mol. Graph. 8 1990 52 56
-
(1990)
J. Mol. Graph.
, vol.8
, pp. 52-56
-
-
Vriend, G.1
-
25
-
-
0000388705
-
Lincs: A linear constraint solver for molecular simulations
-
B. Hess, and H. Bekker J.G.E.M. Fraaije Lincs: A linear constraint solver for molecular simulations J. Comput. Chem. 18 1997 1463 1472
-
(1997)
J. Comput. Chem.
, vol.18
, pp. 1463-1472
-
-
Hess, B.1
Bekker, H.2
Fraaije, J.G.E.M.3
-
26
-
-
33846823909
-
lowast log(n) method for ewald sums in large systems
-
lowast log(n) method for ewald sums in large systems J. Chem. Phys. 98 1993 10089 10092
-
(1993)
J. Chem. Phys.
, vol.98
, pp. 10089-10092
-
-
Darden, T.1
York, D.2
Pedersen, L.3
-
27
-
-
79955082365
-
Implementation of force distribution analysis for molecular dynamics simulations
-
W. Stacklies, C. Seifert, and F. Graeter Implementation of force distribution analysis for molecular dynamics simulations BMC Bioinformatics 12 2011 101
-
(2011)
BMC Bioinformatics
, vol.12
, pp. 101
-
-
Stacklies, W.1
Seifert, C.2
Graeter, F.3
-
28
-
-
56849131626
-
Species-dependent ensembles of conserved conformational states define the Hsp90 chaperone ATPase cycle
-
D.R. Southworth, and D.A. Agard Species-dependent ensembles of conserved conformational states define the Hsp90 chaperone ATPase cycle Mol. Cell 32 2008 631 640
-
(2008)
Mol. Cell
, vol.32
, pp. 631-640
-
-
Southworth, D.R.1
Agard, D.A.2
-
29
-
-
61949212626
-
The large conformational changes of Hsp90 are only weakly coupled to ATP hydrolysis
-
M. Mickler, and M. Hessling T. Hugel The large conformational changes of Hsp90 are only weakly coupled to ATP hydrolysis Nat. Struct. Mol. Biol. 16 2009 281 286
-
(2009)
Nat. Struct. Mol. Biol.
, vol.16
, pp. 281-286
-
-
Mickler, M.1
Hessling, M.2
Hugel, T.3
-
30
-
-
84862098170
-
Probing molecular mechanisms of the Hsp90 chaperone: Biophysical modeling identifies key regulators of functional dynamics
-
A. Dixit, and G.M. Verkhivker Probing molecular mechanisms of the Hsp90 chaperone: biophysical modeling identifies key regulators of functional dynamics PLoS ONE 7 2012 e37605
-
(2012)
PLoS ONE
, vol.7
, pp. 37605
-
-
Dixit, A.1
Verkhivker, G.M.2
-
31
-
-
60649109828
-
Protein allostery, signal transmission and dynamics: A classification scheme of allosteric mechanisms
-
C.-J. Tsai, A. Del Sol, and R. Nussinov Protein allostery, signal transmission and dynamics: a classification scheme of allosteric mechanisms Mol. Biosyst. 5 2009 207 216
-
(2009)
Mol. Biosyst.
, vol.5
, pp. 207-216
-
-
Tsai, C.-J.1
Del Sol, A.2
Nussinov, R.3
-
32
-
-
79960698348
-
Dynamic interaction of hsp90 with its client protein p53
-
S.J. Park, M. Kostic, and H.J. Dyson Dynamic interaction of hsp90 with its client protein p53 J. Mol. Biol. 411 2011 158 173
-
(2011)
J. Mol. Biol.
, vol.411
, pp. 158-173
-
-
Park, S.J.1
Kostic, M.2
Dyson, H.J.3
|