Identification of protease exosite-interacting peptides that enhance substrate cleavage kinetics

Biological Chemistry

Volumn 393, Issue 9, 2012, Pages 933-941

  Jabaiah, Abeer M ^a   Getz, Jennifer A ^a   Witkowski, Witold A ^b   Hardy, Jeanne A ^b   Daugherty, Patrick S ^a  

^a Santa Barbara   (United States)

^b UNIVERSITY OF MASSACHUSETTS   (United States)

Author keywords

CLiPS; Exosite; Protease; Substrate; Thrombin

Indexed keywords

BINDING PROTEIN; CASPASE 7; LIGAND; PEPTIDE; PROTEASE EXOSITE INTERACTING PEPTIDE; PROTEINASE; PROTEINASE ACTIVATED RECEPTOR 1; THROMBIN; UNCLASSIFIED DRUG;

ALLOSTERISM; AMINO ACID SEQUENCE; BACTERIAL CELL; CELL SURFACE; CONFERENCE PAPER; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME KINETICS; FLOW CYTOMETRY; FLUORESCENCE RESONANCE ENERGY TRANSFER; IN VITRO STUDY; METHODOLOGY; NONHUMAN; PEPTIDE ANALYSIS; PEPTIDE LIBRARY; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN MOTIF; SCREENING;

AMINO ACID SEQUENCE; CASPASE 7; CATALYTIC DOMAIN; HUMANS; KINETICS; LIGANDS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PEPTIDES; RECEPTOR, PAR-1; SUBSTRATE SPECIFICITY; THROMBIN;

EID: 84869478356     PISSN: 14316730     EISSN: 14374315     Source Type: Journal    
DOI: 10.1515/hsz-2012-0162     Document Type: Conference Paper

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