Functional modular dissection of debs1-te changes triketide lactone ratios and provides insight into acyl group loading, hydrolysis, and ACP transfer

Biochemistry

Volumn 51, Issue 46, 2012, Pages 9333-9341

  Yan, John ^a   Hazzard, Christopher ^a   Bonnett, Shilah A ^a   Reynolds, Kevin A ^a  

^a PORTLAND STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

6-DEOXYERYTHRONOLIDE B SYNTHASE; ACYL GROUP; EXTENSION MODULE; FUSION PROTEINS; KINETIC PRODUCT; RADIOLABELING; SACCHAROPOLYSPORA ERYTHRAEA; THERMODYNAMIC PRODUCTS;

BACTERIA; DISSECTION; ESTERS; VOLATILE FATTY ACIDS;

LOADING;

6 DEOXYERYTHRONOLIDE B; HYBRID PROTEIN; ISOBUTYRIC ACID; LACTONE; MACROLIDE; PROPIONIC ACID; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL STRUCTURE; CONTROLLED STUDY; DRUG HYDROLYSIS; ISOTOPE LABELING; NONHUMAN; PLASMID; PRIORITY JOURNAL; THERMODYNAMICS;

BASE SEQUENCE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DNA PRIMERS; FERMENTATION; HYDROLYSIS; LACTONES; MASS SPECTROMETRY; PLASMIDS; POLYKETIDE SYNTHASES; POLYMERASE CHAIN REACTION; SACCHAROPOLYSPORA;

SACCHAROPOLYSPORA ERYTHRAEA;

EID: 84869474456     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi300830q     Document Type: Article

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