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Volumn 84, Issue 6, 2012, Pages 441-453

Treating the small airways

Author keywords

Asthma; Chronic obstructive pulmonary disease; Inhaled drug delivery; Small particle aerosols

Indexed keywords

BECLOMETASONE DIPROPIONATE; BECLOMETASONE DIPROPIONATE PLUS FORMOTEROL FUMARATE; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; BUDESONIDE; BUDESONIDE PLUS FORMOTEROL; CICLESONIDE; CORTICOSTEROID; FLUNISOLIDE; FLUTICASONE PROPIONATE; FLUTICASONE PROPIONATE PLUS SALMETEROL; FORMOTEROL; IPRATROPIUM BROMIDE PLUS SALBUTAMOL; LONG ACTING DRUG; MOMETASONE FUROATE; PREDNISONE; SALBUTAMOL;

EID: 84869389761     PISSN: 00257931     EISSN: 14230356     Source Type: Journal    
DOI: 10.1159/000343629     Document Type: Article
Times cited : (66)

References (106)
  • 1
    • 84863527826 scopus 로고    scopus 로고
    • Pathogenesis of small airways in asthma
    • Hamid Q: Pathogenesis of small airways in asthma. Respiration 2012; 84: 4-11
    • (2012) Respiration , vol.84 , pp. 4-11
    • Hamid, Q.1
  • 2
    • 84864867361 scopus 로고    scopus 로고
    • Pathophysiology of the small airways in chronic obstructive pulmonary disease
    • Baraldo S, Turato G, Saetta M: Pathophysiology of the small airways in chronic obstructive pulmonary disease. Respiration 2012; 84: 89-97
    • (2012) Respiration , vol.84 , pp. 89-97
    • Baraldo, S.1    Turato, G.2    Saetta, M.3
  • 3
    • 84866022465 scopus 로고    scopus 로고
    • Physiological measurement of the small airways
    • Verbanck S: Physiological measurement of the small airways. Respiration 2012; 84: 177- 188
    • (2012) Respiration , vol.84 , pp. 177-188
    • Verbanck, S.1
  • 6
    • 75349114365 scopus 로고    scopus 로고
    • Anatomy, pathology, and physiology of the tracheobronchial tree: Emphasis on the distal airways
    • suppl
    • Hyde DM, Hamid Q, Irvin CG: Anatomy, pathology, and physiology of the tracheobronchial tree: Emphasis on the distal airways. J Allergy Clin Immunol 2009; 124(6 suppl): S72-S77
    • (2009) J Allergy Clin Immunol , vol.124 , Issue.6
    • Hyde, D.M.1    Hamid, Q.2    Irvin, C.G.3
  • 11
    • 58249092645 scopus 로고    scopus 로고
    • The effect of montelukast on exhaled nitric oxide of alveolar and bronchial origin in inhaled corticosteroid-treated asthma
    • Fritscher LG, Rodrigues MT, Zamel N, Chapman KR: The effect of montelukast on exhaled nitric oxide of alveolar and bronchial origin in inhaled corticosteroid-treated asthma. Respir Med 2009; 103: 296-300
    • (2009) Respir Med , vol.103 , pp. 296-300
    • Fritscher, L.G.1    Rodrigues, M.T.2    Zamel, N.3    Chapman, K.R.4
  • 12
    • 0016729264 scopus 로고
    • Historical review of the use of parasympatholytic agents in the treatment of respiratory disorders
    • suppl
    • Gandevia B: Historical review of the use of parasympatholytic agents in the treatment of respiratory disorders. Postgrad Med J 1975; 51(7 suppl):13-20
    • (1975) Postgrad Med J , vol.51 , Issue.7 , pp. 13-20
    • Gandevia, B.1
  • 13
    • 0028230326 scopus 로고
    • The evolution of inhaler technology
    • Grossman J: The evolution of inhaler technology. J Asthma 1994; 31: 55-64 (Pubitemid 24087756)
    • (1994) Journal of Asthma , vol.31 , Issue.1 , pp. 55-64
    • Grossman, J.1
  • 14
    • 0038094385 scopus 로고    scopus 로고
    • Inhalation therapy: Technological milestones in asthma treatment
    • DOI 10.1016/S0169-409X(03)00077-2
    • Dalby R, Suman J: Inhalation therapy: Technological milestones in asthma treatment. Adv Drug Deliv Rev 2003; 55: 779-791 (Pubitemid 36776793)
    • (2003) Advanced Drug Delivery Reviews , vol.55 , Issue.7 , pp. 779-791
    • Dalby, R.1    Suman, J.2
  • 15
    • 0028047817 scopus 로고
    • Medical personnel's knowledge of and ability to use inhaling devices: Metered-dose inhalers, spacing chambers, and breath-actuated dry powder inhalers
    • Hanania NA, Wittman R, Kesten S, Chapman KR: Medical personnel's knowledge of and ability to use inhaling devices. Metereddose inhalers, spacing chambers, and breathactuated dry powder inhalers. Chest 1994; 105: 111-116 (Pubitemid 24029087)
    • (1994) Chest , vol.105 , Issue.1 , pp. 111-116
    • Hanania, N.A.1    Wittman, R.2    Kesten, S.3    Chapman, K.R.4
  • 17
    • 0025327891 scopus 로고
    • Comparison of bronchodilator responses and deposition patterns of salbutamol inhaled from a pressurised metered dose inhaler, as a dry powder, and as a nebulised solution
    • Zainudin BM, Biddiscombe M, Tolfree SE, Short M, Spiro SG: Comparison of bronchodilator responses and deposition patterns of salbutamol inhaled from a pressurised metered dose inhaler, as a dry powder, and as a nebulised solution. Thorax 1990; 45: 469-473 (Pubitemid 20225175)
    • (1990) Thorax , vol.45 , Issue.6 , pp. 469-473
    • Zainudin, B.M.Z.1    Biddiscombe, M.2    Tolfree, S.E.J.3    Short, M.4    Spiro, S.G.5
  • 18
    • 0344513087 scopus 로고    scopus 로고
    • Pulmonary drug delivery. Part I: Physiological factors affecting therapeutic effectiveness of aerosolized medications
    • DOI 10.1046/j.1365-2125.2003.01892.x
    • Labiris NR, Dolovich MB: Pulmonary drug delivery. Part I: Physiological factors affecting therapeutic effectiveness of aerosolized medications (review). Br J Clin Pharmacol 2003; 56: 588-599 (Pubitemid 37491710)
    • (2003) British Journal of Clinical Pharmacology , vol.56 , Issue.6 , pp. 588-599
    • Labiris, N.R.1    Dolovich, M.B.2
  • 20
    • 84909715238 scopus 로고
    • Assessment of airway geometry with inert aerosols
    • Heyder J: Assessment of airway geometry with inert aerosols. J Aerosol Med 1989; 2: 89-97
    • (1989) J Aerosol Med , vol.2 , pp. 89-97
    • Heyder, J.1
  • 23
    • 0016322177 scopus 로고
    • Stratospheric sink for chlorofluoromethanes: Chlorine atomcatalysed destruction of ozone
    • Molina MJ, Rowland FS: Stratospheric sink for chlorofluoromethanes: Chlorine atomcatalysed destruction of ozone. Nature 1974; 249: 810-812
    • (1974) Nature , vol.249 , pp. 810-812
    • Molina, M.J.1    Rowland, F.S.2
  • 24
    • 0032805050 scopus 로고    scopus 로고
    • New delivery systems and propellants
    • Dolovich M: New delivery systems and propellants. Can Respir J 1999; 6: 290-295
    • (1999) Can Respir J , vol.6 , pp. 290-295
    • Dolovich, M.1
  • 25
    • 1842608807 scopus 로고    scopus 로고
    • Hydrofluoroalkane formulations of inhaled corticosteroids for the treatment of asthma
    • DOI 10.2165/00151829-200403010-00005
    • Zeidler M, Corren J: Hydrofluoroalkane formulations of inhaled corticosteroids for the treatment of asthma. Treat Respir Med 2004; 3: 35-44 (Pubitemid 38444330)
    • (2004) Treatments in Respiratory Medicine , vol.3 , Issue.1 , pp. 35-44
    • Zeidler, M.1    Corren, J.2
  • 26
    • 33847420001 scopus 로고    scopus 로고
    • Relevance of pharmacokinetics and pharmacodynamics of inhaled corticosteroids to asthma
    • DOI 10.1183/09031936.00074905
    • Derendorf H, Nave R, Drollmann A, Cerasoli F, Wurst W: Relevance of pharmacokinetics and pharmacodynamics of inhaled corticosteroids to asthma. Eur Respir J 2006; 28: 1042-1050 (Pubitemid 46335529)
    • (2006) European Respiratory Journal , vol.28 , Issue.5 , pp. 1042-1050
    • Derendorf, H.1    Nave, R.2    Drollmann, A.3    Cerasoli, F.4    Wurst, W.5
  • 27
    • 0036174758 scopus 로고    scopus 로고
    • Therapeutic significance of distal airway inflammation in asthma
    • Martin RJ: Therapeutic significance of distal airway inflammation in asthma. J Allergy Clin Immunol 2002; 109(2 suppl):S447-S460 (Pubitemid 34155294)
    • (2002) Journal of Allergy and Clinical Immunology , vol.109 , Issue.2 SUPPL.
    • Martin, R.J.1
  • 29
    • 0033894918 scopus 로고    scopus 로고
    • Pharmaceutical transition to non-CFC pressurized metered dose inhalers
    • DOI 10.1053/rmed.2000.0850
    • Cripps A, Riebe M, Schulze M, Woodhouse R: Pharmaceutical transition to non-CFC pressurized metered dose inhalers. Respir Med 2000; 94(suppl B):S3-S9 (Pubitemid 30599243)
    • (2000) Respiratory Medicine , vol.94 , Issue.SUPPL. B
    • Cripps, A.1    Riebe, M.2    Schulze, M.3    Woodhouse, R.4
  • 30
    • 33846999016 scopus 로고    scopus 로고
    • ® technology
    • DOI 10.1016/j.pupt.2006.05.005, PII S1094553906000538
    • Acerbi D, Brambilla G, Kottakis I: Advances in asthma and COPD management: Delivering CFC-free inhaled therapy using Modulite technology. Pulm Pharmacol Ther 2007; 20: 290-303 (Pubitemid 46242202)
    • (2007) Pulmonary Pharmacology and Therapeutics , vol.20 , Issue.3 , pp. 290-303
    • Acerbi, D.1    Brambilla, G.2    Kottakis, I.3
  • 31
    • 0032438394 scopus 로고    scopus 로고
    • Improved airway targeting with the CFC-free HFA-beclomethasone metered- dose inhaler compared with CFC-beclomethasone
    • DOI 10.1183/09031936.98.12061346
    • Leach CL, Davidson PJ, Boudreau RJ: Improved airway targeting with the CFC-free HFA-beclomethasone metered-dose inhaler compared with CFC-beclomethasone. Eur Respir J 1998; 12: 1346-1353 (Pubitemid 29011427)
    • (1998) European Respiratory Journal , vol.12 , Issue.6 , pp. 1346-1353
    • Leach, C.L.1    Davidson, P.J.2    Boudreau, R.J.3
  • 33
    • 67649121826 scopus 로고    scopus 로고
    • Comparative in vitro evaluation of four corticosteroid metered dose inhalers: Consistency of delivered dose and particle size distribution
    • de Vries TW, Rottier BL, Gjaltema D, Hagedoorn P, Frijlink HW, de Boer AH: Comparative in vitro evaluation of four corticosteroid metered dose inhalers: Consistency of delivered dose and particle size distribution. Respir Med 2009; 103: 1167-1173
    • (2009) Respir Med , vol.103 , pp. 1167-1173
    • De Vries, T.W.1    Rottier, B.L.2    Gjaltema, D.3    Hagedoorn, P.4    Frijlink, H.W.5    De Boer, A.H.6
  • 34
    • 33747345377 scopus 로고    scopus 로고
    • Beclomethasone dipropionate and formoterol association within a combination HFA solution MDI
    • Lewis D, Brambilla G, Church T, Meakin B: Beclomethasone dipropionate and formoterol association within a combination HFA solution MDI. Respir Drug Deliv 2006; 3: 939- 942
    • (2006) Respir Drug Deliv , vol.3 , pp. 939-942
    • Lewis, D.1    Brambilla, G.2    Church, T.3    Meakin, B.4
  • 35
    • 0036036475 scopus 로고    scopus 로고
    • Lung deposition of hydrofluoroalkane-134a beclomethasone is greater than that of chlorofluorocarbon fluticasone and chlorofluorocarbon beclomethasone: A cross-over study in healthy volunteers
    • DOI 10.1378/chest.122.2.510
    • Leach CL, Davidson PJ, Hasselquist BE, Boudreau RJ: Lung deposition of hydrofluoroalkane- 134a beclomethasone is greater than that of chlorofluorocarbon fluticasone and chlorofluorocarbon beclomethasone: A cross-over study in healthy volunteers. Chest 2002; 122: 510-516 (Pubitemid 35002128)
    • (2002) Chest , vol.122 , Issue.2 , pp. 510-516
    • Leach, C.L.1    Davidson, P.J.2    Hasselquist, B.E.3    Boudreau, R.J.4
  • 36
    • 84857694861 scopus 로고    scopus 로고
    • Characterization of respiratory deposition of fluticasone-salmeterol hydrofluoroalkane-134a and hydrofluoroalkane- 134a beclomethasone in asthmatic patients
    • Leach CL, Kuehl PJ, Chand R, Ketai L, Norenberg JP, McDonald JD: Characterization of respiratory deposition of fluticasone-salmeterol hydrofluoroalkane-134a and hydrofluoroalkane- 134a beclomethasone in asthmatic patients. Ann Allergy Asthma Immunol 2012; 108: 195-200
    • (2012) Ann Allergy Asthma Immunol , vol.108 , pp. 195-200
    • Leach, C.L.1    Kuehl, P.J.2    Chand, R.3    Ketai, L.4    Norenberg, J.P.5    McDonald, J.D.6
  • 37
    • 32644435870 scopus 로고    scopus 로고
    • 99mTc-labeled ciclesonide administered via HFA-MDI to patients with asthma
    • DOI 10.1016/j.rmed.2005.09.027, PII S0954611105004051
    • Newman S, Salmon A, Nave R, Drollmann A: High lung deposition of 99m Tc-labeled ciclesonide administered via HFA-MDI to patients with asthma. Respir Med 2006; 100: 375-384 (Pubitemid 43239871)
    • (2006) Respiratory Medicine , vol.100 , Issue.3 , pp. 375-384
    • Newman, S.1    Salmon, A.2    Nave, R.3    Drollmann, A.4
  • 41
    • 0022646915 scopus 로고
    • The effect of bronchial obstruction on central airway deposition of a saline aerosol in patients with asthma
    • Laube BL, Swift DL, Wagner HN, Norman PS, Adams GK: The effect of bronchial obstruction on central airway deposition of a saline aerosol in patients with asthma. Am Rev Respir Dis 1986; 133: 740-743 (Pubitemid 16116495)
    • (1986) American Review of Respiratory Disease , vol.133 , Issue.5 , pp. 740-743
    • Laube, B.L.1    Swift, D.L.2    Wagner Jr., H.N.3
  • 42
    • 0023680103 scopus 로고
    • Effect of methacholine induced bronchoconstriction on the pulmonary distribution and plasma pharmacokinetics of inhaled sodium cromoglycate in subjects with normal and hyperreactive airways
    • Richards R, Haas A, Simpson S, Britten A, Renwick A, Holgate S: Effect of methacholine induced bronchoconstriction on the pulmonary distribution and plasma pharmacokinetics of inhaled sodium cromoglycate in subjects with normal and hyperreactive airways. Thorax 1988; 43: 611-616
    • (1988) Thorax , vol.43 , pp. 611-616
    • Richards, R.1    Haas, A.2    Simpson, S.3    Britten, A.4    Renwick, A.5    Holgate, S.6
  • 43
    • 56749121960 scopus 로고    scopus 로고
    • Beclomethasone/formoterol fixed combination for the management of asthma: Patient considerations
    • Nicolini G, Scichilone N, Bizzi A, Papi A, Fabbri LM: Beclomethasone/formoterol fixed combination for the management of asthma: Patient considerations. Ther Clin Risk Manag 2008; 4: 855-864
    • (2008) Ther Clin Risk Manag , vol.4 , pp. 855-864
    • Nicolini, G.1    Scichilone, N.2    Bizzi, A.3    Papi, A.4    Fabbri, L.M.5
  • 44
    • 77949663450 scopus 로고    scopus 로고
    • Comparison of effectiveness in ciclesonide and fluticasone propionate on small airway function in mild asthma
    • Hoshino M: Comparison of effectiveness in ciclesonide and fluticasone propionate on small airway function in mild asthma. Allergol Int 2010; 59: 59-66
    • (2010) Allergol Int , vol.59 , pp. 59-66
    • Hoshino, M.1
  • 46
    • 23744448863 scopus 로고    scopus 로고
    • Clinical applications of forced oscillation to assess peripheral airway function
    • DOI 10.1016/j.resp.2005.05.026, PII S156990480500159X
    • Goldman MD, Saadeh C, Ross D: Clinical applications of forced oscillation to assess peripheral airway function. Respir Physiol Neurobiol 2005; 148: 179-194 (Pubitemid 41135872)
    • (2005) Respiratory Physiology and Neurobiology , vol.148 , pp. 179-194
    • Goldman, M.D.1    Saadeh, C.2    Ross, D.3
  • 47
    • 77949791521 scopus 로고    scopus 로고
    • Comparison of inspiratory and expiratory resistance and reactance in patients with asthma and chronic obstructive pulmonary disease
    • Paredi P, Goldman M, Alamen A, Ausin P, Usmani OS, Pride NB, Barnes PJ: Comparison of inspiratory and expiratory resistance and reactance in patients with asthma and chronic obstructive pulmonary disease. Thorax 2010; 65: 263-267
    • (2010) Thorax , vol.65 , pp. 263-267
    • Paredi, P.1    Goldman, M.2    Alamen, A.3    Ausin, P.4    Usmani, O.S.5    Pride, N.B.6    Barnes, P.J.7
  • 48
    • 0029152965 scopus 로고
    • Comparison of samples collected by sputum induction and bronchoscopy from asthmatic and healthy subjects
    • Fahy JV, Wong H, Liu J, Boushey HA: Comparison of samples collected by sputum induction and bronchoscopy from asthmatic and healthy subjects. Am J Respir Crit Care Med 1995; 152: 53-58
    • (1995) Am J Respir Crit Care Med , vol.152 , pp. 53-58
    • Fahy, J.V.1    Wong, H.2    Liu, J.3    Boushey, H.A.4
  • 49
    • 73449086493 scopus 로고    scopus 로고
    • Global Initiative for Asthma (GINA): GINA Report revised 2011
    • Global Initiative for Asthma (GINA): GINA Report, Global Strategy for Asthma Management and Prevention, revised 2011. http:// www.ginasthma.org
    • Global Strategy for Asthma Management and Prevention
  • 51
    • 0037901033 scopus 로고    scopus 로고
    • Stepping down inhaled corticosteroids in asthma: Randomised controlled trial
    • British Thoracic Society (BTS) and Scottish Intercollegiate Guidelines Network (SIGN): British Guideline on the Management of Asthma, revised 2012. http://www.britthoracic. org.uk/guidelines/asthma-guidelines. aspx. 51 Hawkins G, McMahon AD, Twaddle S, Wood SF, Ford I, Thomson NC: Stepping down inhaled corticosteroids in asthma: Randomised controlled trial. BMJ 2003; 326: 1115-1118 (Pubitemid 36613440)
    • (2003) British Medical Journal , vol.326 , Issue.7399 , pp. 1115-1118
    • Hawkins, G.1    McMahon, A.D.2    Twaddle, S.3    Wood, S.F.4    Ford, I.5    Thomson, N.C.6
  • 53
    • 77953928883 scopus 로고    scopus 로고
    • Down-titration from high-dose combination therapy in asthma: Removal of long-acting beta(2)- agonist
    • Reddel HK, Gibson PG, Peters MJ, Wark PA, Sand IB, Hoyos CM, Jenkins CR: Down-titration from high-dose combination therapy in asthma: Removal of long-acting beta(2)- agonist. Respir Med 2010; 104: 1110-1120
    • (2010) Respir Med , vol.104 , pp. 1110-1120
    • Reddel, H.K.1    Gibson, P.G.2    Peters, M.J.3    Wark, P.A.4    Sand, I.B.5    Hoyos, C.M.6    Jenkins, C.R.7
  • 54
    • 48949114938 scopus 로고    scopus 로고
    • Maintaining asthma control in persistent asthma: Comparison of three strategies in a 6-month double- blind randomised study
    • Godard P, Greillier P, Pigearias B, Nachbaur G, Desfourgeres JL, Attali V: Maintaining asthma control in persistent asthma: Comparison of three strategies in a 6-month double- blind randomised study. Respir Med 2008; 102: 1124-1131
    • (2008) Respir Med , vol.102 , pp. 1124-1131
    • Godard, P.1    Greillier, P.2    Pigearias, B.3    Nachbaur, G.4    Desfourgeres, J.L.5    Attali, V.6
  • 55
    • 33644763830 scopus 로고    scopus 로고
    • Asthma control can be maintained when fluticasone propionate/salmeterol in a single inhaler is stepped down
    • DOI 10.1016/j.jaci.2005.11.036, PII S0091674905025947
    • Bateman ED, Jacques L, Goldfrad C, Atienza T, Mihaescu T, Duggan M: Asthma control can be maintained when fluticasone propionate/ salmeterol in a single inhaler is stepped down. J Allergy Clin Immunol 2006; 117: 563-570 (Pubitemid 43340219)
    • (2006) Journal of Allergy and Clinical Immunology , vol.117 , Issue.3 , pp. 563-570
    • Bateman, E.D.1    Jacques, L.2    Goldfrad, C.3    Atienza, T.4    Mihaescu, T.5    Duggan, M.6
  • 56
    • 13844322153 scopus 로고    scopus 로고
    • Step-down compared to fixed-dose treatment with inhaled fluticasone propionate in asthma
    • DOI 10.1378/chest.127.1.117
    • Foresi A, Mastropasqua B, Chetta A, D'Ippolito R, Testi R, Olivieri D, Pelucchi A: Step-down compared to fixed-dose treatment with inhaled fluticasone propionate in asthma. Chest 2005; 127: 117-124 (Pubitemid 41724564)
    • (2005) Chest , vol.127 , Issue.1 , pp. 117-124
    • Foresi, A.1    Mastropasqua, B.2    Chetta, A.3    D'Ippolito, R.4    Testi, R.5    Olivieri, D.6    Pelucchi, A.7
  • 57
    • 34247645201 scopus 로고    scopus 로고
    • A proof of concept study to evaluate stepping down the dose of fluticasone in combination with salmeterol and tiotropium in severe persistent asthma
    • DOI 10.1016/j.rmed.2006.11.001, PII S0954611106005506
    • Fardon T, Haggart K, Lee DK, Lipworth BJ: A proof of concept study to evaluate stepping down the dose of fluticasone in combination with salmeterol and tiotropium in severe persistent asthma. Respir Med 2007; 101: 1218-1228 (Pubitemid 46679499)
    • (2007) Respiratory Medicine , vol.101 , Issue.6 , pp. 1218-1228
    • Fardon, T.1    Haggart, K.2    Lee, D.K.C.3    Lipworth, B.J.4
  • 58
    • 0036286458 scopus 로고    scopus 로고
    • Step-down therapy with low-dose fluticasone-salmeterol combination or medium-dose hydrofluoroalkane 134a-beclomethasone alone
    • DOI 10.1067/mai.2002.123869
    • Fowler SJ, Currie GP, Lipworth BJ: Stepdown therapy with low-dose fluticasone salmeterol combination or medium dose hydrofluoroalkane 134a-beclomethasone alone. J Allergy Clin Immunol 2002; 109: 929-935 (Pubitemid 34634301)
    • (2002) Journal of Allergy and Clinical Immunology , vol.109 , Issue.6 , pp. 929-935
    • Fowler, S.J.1    Currie, G.P.2    Lipworth, B.J.3
  • 59
    • 0029125012 scopus 로고
    • Aerosol particle generation from dry powder inhalers: Can they equal pressurized metered dose inhalers
    • SUPPL3
    • Olsson B: Aerosol particle generation from dry powder inhalers: Can they equal pressurized metered dose inhalers? J Aerosol Med 1995; 8(suppl 3):S13-S18
    • (1995) J Aerosol Med , vol.8
    • Olsson, B.1
  • 60
    • 0031903693 scopus 로고    scopus 로고
    • Improved delivery of inhaled steroids to the large and small airways
    • suppl A
    • Leach CL: Improved delivery of inhaled steroids to the large and small airways. Respir Med 1998; 92(suppl A):3-8
    • (1998) Respir Med , vol.92 , pp. 3-8
    • Leach, C.L.1
  • 61
    • 33646475553 scopus 로고    scopus 로고
    • Ciclesonide reduces the need for oral steroid use in adult patients with severe, persistent asthma
    • Bateman E, Karpel J, Casale T, Wenzel S, Banerji D: Ciclesonide reduces the need for oral steroid use in adult patients with severe, persistent asthma. Chest 2006; 129: 1176-1187
    • (2006) Chest , vol.129 , pp. 1176-1187
    • Bateman, E.1    Karpel, J.2    Casale, T.3    Wenzel, S.4    Banerji, D.5
  • 63
    • 0031925428 scopus 로고    scopus 로고
    • Oral glucocorticosteroid-sparing effect of budesonide administered by Turbuhaler: A double-blind, placebo-controlled study in adults with moderate- to-severe chronic asthma
    • Nelson HS, Bernstein IL, Fink J, et al: Oral glucocorticosteroid-sparing effect of budesonide administered by Turbuhaler: A double-blind, placebo-controlled study in adults with moderate-to-severe chronic asthma. Pulmicort Turbuhaler Study Group. Chest 1998; 113: 1264-1271 (Pubitemid 28223814)
    • (1998) Chest , vol.113 , Issue.5 , pp. 1264-1271
    • Nelson, H.S.1    Bernstein, I.L.2    Fink, J.3    Edwards, T.B.4    Spector, S.L.5    Storms, W.W.6    Tashkin, D.P.7
  • 65
    • 84862621035 scopus 로고    scopus 로고
    • Step-down from high dose fixed combination therapy in asthma patients: A randomized controlled trial
    • Papi A, Nicolini G, Crimi N, Fabbri L, Olivieri D, Rossi A, Paggiaro P: Step-down from high dose fixed combination therapy in asthma patients: A randomized controlled trial. Respir Res 2012; 13: 54
    • (2012) Respir Res , vol.13 , pp. 54
    • Papi, A.1    Nicolini, G.2    Crimi, N.3    Fabbri, L.4    Olivieri, D.5    Rossi, A.6    Paggiaro, P.7
  • 66
    • 79955714713 scopus 로고    scopus 로고
    • Asthma treatment guidelines meet the real world
    • Dahlén S-E, Dahlén B, Drazen JM: Asthma treatment guidelines meet the real world. N Engl J Med 2011; 364: 1769-1770
    • (2011) N Engl J Med , vol.364 , pp. 1769-1770
    • Dahlén, S.-E.1    Dahlén, B.2    Drazen, J.M.3
  • 67
    • 79955736485 scopus 로고    scopus 로고
    • Pragmatic trials - guides to better patient care?
    • Ware JH, Hamel MB: Pragmatic trials - guides to better patient care? N Engl J Med 2011; 364: 1685-1687
    • (2011) N Engl J Med , vol.364 , pp. 1685-1687
    • Ware, J.H.1    Hamel, M.B.2
  • 68
    • 84655170190 scopus 로고    scopus 로고
    • Real-life prospective study on asthma control in Italy: Cross-sectional phase results
    • PRISMA (PRospectIve Study On AsthMA Control) Study Group
    • Allegra L, Cremonesi G, Girbino G, Ingrassia E, Marsico S, Nicolini G, Terzano C; PRISMA (PRospectIve Study on asthMA control) Study Group. Real-life prospective study on asthma control in Italy: Cross-sectional phase results. Respir Med 2012; 106: 205-214
    • (2012) Respir Med , vol.106 , pp. 205-214
    • Allegra, L.1    Cremonesi, G.2    Girbino, G.3    Ingrassia, E.4    Marsico, S.5    Nicolini, G.6    Terzano, C.7
  • 71
    • 0014424329 scopus 로고
    • Site and nature of airway obstruction in chronic obstructive lung disease
    • Hogg JC, Macklem PT, Thurlbeck WM: Site and nature of airway obstruction in chronic obstructive lung disease. N Engl J Med 1968; 278: 1355-1360
    • (1968) N Engl J Med , vol.278 , pp. 1355-1360
    • Hogg, J.C.1    Macklem, P.T.2    Thurlbeck, W.M.3
  • 72
    • 2942735127 scopus 로고    scopus 로고
    • Small airways in COPD
    • DOI 10.1056/NEJMp048102
    • Barnes PJ: Small airways in COPD. N Engl J Med 2004; 350: 2635-2637 (Pubitemid 38787995)
    • (2004) New England Journal of Medicine , vol.350 , Issue.26 , pp. 2635-2637
    • Barnes, P.J.1
  • 74
    • 0032778472 scopus 로고    scopus 로고
    • Spirometric correlates of improvement in exercise performance after anticholinergic therapy in chronic obstructive pulmonary disease
    • O'Donnell DE, Lam MIU, Webb KA: Spirometric correlates of improvement in exercise performance after anticholinergic therapy in chronic obstructive pulmonary disease. Am J Respir Crit Care Med 1999; 160: 542-549 (Pubitemid 29380670)
    • (1999) American Journal of Respiratory and Critical Care Medicine , vol.160 , Issue.2 , pp. 542-549
    • O'Donnell, D.E.1    Lam, M.2    Webb, K.A.3
  • 77
    • 0029115523 scopus 로고
    • Protective effects of a glucocorticoid on downregulation of pulmonary beta-2 adrenergic receptors in vivo
    • Mak JC, Nishikawa M, Shirasaki H, Miyayasu K, Barnes PJ: Protective effects of a glucocorticoid on downregulation of pulmonary beta-2 adrenergic receptors in vivo. J Clin Invest 1995; 96: 99-106
    • (1995) J Clin Invest , vol.96 , pp. 99-106
    • Mak, J.C.1    Nishikawa, M.2    Shirasaki, H.3    Miyayasu, K.4    Barnes, P.J.5
  • 78
    • 0033534727 scopus 로고    scopus 로고
    • Ligand-independent activation of the glucocorticoid receptor by beta2-adrenergic receptor agonists in primary human lung fibroblasts and vascular smooth muscle cells
    • Eickelberg O, Roth M, Lorx R, Bruce V, Rudiger J, Johnson M, Block LM: Ligand-independent activation of the glucocorticoid receptor by beta2-adrenergic receptor agonists in primary human lung fibroblasts and vascular smooth muscle cells. J Biol Chem 1999; 274: 1005-1010
    • (1999) J Biol Chem , vol.274 , pp. 1005-1010
    • Eickelberg, O.1    Roth, M.2    Lorx, R.3    Bruce, V.4    Rudiger, J.5    Johnson, M.6    Block, L.M.7
  • 79
    • 0037180086 scopus 로고    scopus 로고
    • 2 agonists on bronchial airway smooth muscle cells through synchronised cellular signalling
    • DOI 10.1016/S0140-6736(02)11319-5
    • Roth M, Johnson PR, Rudiger JJ, King GG, Ge Q, Burgess JK, Anderson G, Tamm M, Black JL: Interaction between glucocorticoids and beta2 agonists on bronchial airway smooth muscle cells through synchronised cellular signalling. Lancet 2002; 360: 1293- 1299 (Pubitemid 35284621)
    • (2002) Lancet , vol.360 , Issue.9342 , pp. 1293-1299
    • Roth, M.1    Johnson, P.R.A.2    Rudiger, J.J.3    King, G.G.4    Ge, Q.5    Burgess, J.K.6    Anderson, G.7    Tamm, M.8    Black, J.L.9
  • 80
    • 24944482440 scopus 로고    scopus 로고
    • S'ng CT, Kotoula V, Savic S, Tamm M, Roth M: Steroids and - 2 agonists regulate hyaluronan metabolism in asthma airway smooth muscle cells. Am J Respir Cell Mol Biol 2012, E-pub ahead of print. 81 Usmani OS, Ito K, Maneechotesuwan K, Ito M, Johnson M, Barnes PJ, Adcock IM: Glucocorticoid receptor nuclear translocation in airway cells after inhaled combination therapy
    • Papakonstantinou E, Klagas I, Karakiulakis G, Hostettler K, S'ng CT, Kotoula V, Savic S, Tamm M, Roth M: Steroids and - 2 agonists regulate hyaluronan metabolism in asthma airway smooth muscle cells. Am J Respir Cell Mol Biol 2012, E-pub ahead of print. 81 Usmani OS, Ito K, Maneechotesuwan K, Ito M, Johnson M, Barnes PJ, Adcock IM: Glucocorticoid receptor nuclear translocation in airway cells after inhaled combination therapy. Am J Respir Crit Care Med 2005; 172: 704-712
    • (2005) Am J Respir Crit Care Med , vol.172 , pp. 704-712
    • Papakonstantinou, E.1    Klagas, I.2    Karakiulakis, G.3    Hostettler, K.4
  • 82
    • 0032724631 scopus 로고    scopus 로고
    • An antiinflammatory effect of salmeterol, a long-acting - 2 agonist, assessed in airway biopsies and bronchoalveolar lavage in asthma
    • Li X, Ward C, Thien F, Bish R, Bamford T, Bao X, Bailey M, Wilson JW, Walters EH: An antiinflammatory effect of salmeterol, a long-acting - 2 agonist, assessed in airway biopsies and bronchoalveolar lavage in asthma. Am J Respir Crit Care Med 1999; 160: 1493-1499
    • (1999) Am J Respir Crit Care Med , vol.160 , pp. 1493-1499
    • Li, X.1    Ward, C.2    Thien, F.3    Bish, R.4    Bamford, T.5    Bao, X.6    Bailey, M.7    Wilson, J.W.8    Walters, E.H.9
  • 84
    • 0028264310 scopus 로고
    • Added salmeterol versus higher-dose corticosteroid in asthma patients with symptoms on existing inhaled corticosteroid
    • DOI 10.1016/S0140-6736(94)92996-3
    • Greening AP, Ind PW, Northfield M, Shaw G: Added salmeterol versus higher-dose corticosteroid in asthma patients with symptoms on existing inhaled corticosteroid. Lancet 1994; 344: 219-224 (Pubitemid 24229008)
    • (1994) Lancet , vol.344 , Issue.8917 , pp. 219-224
    • Greening, A.P.1    Ind, P.W.2    Northfield, M.3    Shaw, G.4
  • 86
    • 1842370350 scopus 로고    scopus 로고
    • Effect of inhaled formoterol and budesonide on exacerbations of asthma. Formoterol and Corticosteroids Establishing Therapy (FACET) International Study Group
    • Pauwels RA, Lofdahl CG, Postma DS, Tattersfield AE, O'Byrne P, Barnes PJ, Ullman A: Effect of inhaled formoterol and budesonide on exacerbations of asthma. Formoterol and Corticosteroids Establishing Therapy (FACET) International Study Group. N Engl J Med 1997; 337: 1405-1411
    • (1997) N Engl J Med , vol.337 , pp. 1405-1411
    • Pauwels, R.A.1    Lofdahl, C.G.2    Postma, D.S.3    Tattersfield, A.E.4    O'Byrne, P.5    Barnes, P.J.6    Ullman, A.7
  • 88
    • 0034690661 scopus 로고    scopus 로고
    • Meta-analysis of increased dose of inhaled steroid or addition of salmeterol in symptomatic asthma (MIASMA)
    • Shrewsbury S, Pyke S, Britton M: Meta-analysis of increased dose of inhaled steroid or addition of salmeterol in symptomatic asthma (MIASMA). BMJ 2000; 320: 1368-1373 (Pubitemid 30261116)
    • (2000) British Medical Journal , vol.320 , Issue.7246 , pp. 1368-1373
    • Shrewsbury, S.1    Pyke, S.2    Britton, M.3
  • 89
    • 0035013066 scopus 로고    scopus 로고
    • Addition of salmeterol to low-dose fluticasone versus higher-dose fluticasone: An analysis of asthma exacerbations
    • DOI 10.1067/mai.2001.114709
    • Matz J, Emmett A, Rickard K, Kalberg C: Addition of salmeterol to low-dose fluticasone versus higher-dose fluticasone: An analysis of asthma exacerbations. J Allergy Clin Immunol 2001; 107: 783-789 (Pubitemid 32436910)
    • (2001) Journal of Allergy and Clinical Immunology , vol.107 , Issue.5 SUPPL. , pp. 783-789
    • Matz, J.1    Emmett, A.2    Rickard, K.3    Kalberg, C.4
  • 91
    • 58049218972 scopus 로고    scopus 로고
    • Lung function and asthma control with beclomethasone and formoterol in a single inhaler
    • Huchon G, Magnussen H, Chuchalin A, Dymek L, Gonod FB, Bousquet J: Lung function and asthma control with beclomethasone and formoterol in a single inhaler. Respir Med 2009; 103: 41-49
    • (2009) Respir Med , vol.103 , pp. 41-49
    • Huchon, G.1    Magnussen, H.2    Chuchalin, A.3    Dymek, L.4    Gonod, F.B.5    Bousquet, J.6
  • 95
    • 0036794862 scopus 로고    scopus 로고
    • Relationship between exacerbation frequency and lung function decline in chronic obstructive pulmonary disease
    • DOI 10.1136/thorax.57.10.847
    • Donaldson GC, Seemungal TA, Bhowmik A, Wedzicha JA: Relationship between exacerbation frequency and lung function decline in chronic obstructive pulmonary disease. Thorax 2002; 57: 847-852 (Pubitemid 35178607)
    • (2002) Thorax , vol.57 , Issue.10 , pp. 847-852
    • Donaldson, G.C.1    Seemungal, T.A.R.2    Bhowmik, A.3    Wedzicha, J.A.4
  • 99
    • 67649421218 scopus 로고    scopus 로고
    • Interpreting clinical trial results of patient-perceived onset of effect in asthma: Methods and results of a Delphi panel
    • Harding G, Leidy NK, Meddis D, Kleinman L, Wagner S, O'Brien CD: Interpreting clinical trial results of patient-perceived onset of effect in asthma: Methods and results of a Delphi panel. Curr Med Res Opin 2009; 25: 1563-1571
    • (2009) Curr Med Res Opin , vol.25 , pp. 1563-1571
    • Harding, G.1    Leidy, N.K.2    Meddis, D.3    Kleinman, L.4    Wagner, S.5    O'Brien, C.D.6
  • 100
    • 20144384260 scopus 로고    scopus 로고
    • U.S. regulatory perspective on the minimal clinically important difference in chronic obstructive pulmonary disease
    • DOI 10.1081/COPD-200050660
    • Meyer RJ: U.S. regulatory perspective on the minimal clinically important difference in chronic obstructive pulmonary disease. COPD 2005; 2: 47-49 (Pubitemid 40776222)
    • (2005) COPD: Journal of Chronic Obstructive Pulmonary Disease , vol.2 , Issue.1 , pp. 47-49
    • Meyer, R.J.1
  • 101
    • 20144384492 scopus 로고    scopus 로고
    • The relation between the minimally important difference and patient benefit
    • DOI 10.1081/COPD-200051249
    • Norman GR: The relation between the minimally important difference and patient benefit. COPD 2005; 2: 69-73 (Pubitemid 40776226)
    • (2005) COPD: Journal of Chronic Obstructive Pulmonary Disease , vol.2 , Issue.1 , pp. 69-73
    • Norman, G.R.1
  • 102
    • 84866991691 scopus 로고    scopus 로고
    • Tomographic imaging of small airways
    • King GG: Tomographic imaging of small airways. Respiration 2012;84:265-274
    • (2012) Respiration , vol.84 , pp. 265-274
    • King, G.G.1
  • 106
    • 84863513518 scopus 로고    scopus 로고
    • Unravelling the small airways: Structure-function-treatment relationships in asthma and COPD
    • Usmani OS: Unravelling the small airways: structure-function-treatment relationships in asthma and COPD. Respiration 2012; 84: 1-3.
    • (2012) Respiration , vol.84 , pp. 1-3
    • Usmani, O.S.1


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