Asthma treatment guidelines meet the real world

New England Journal of Medicine

Volumn 364, Issue 18, 2011, Pages 1769-1770

  Dahlén, Sven Erik ^a   Dahlén, Barbro ^a   Drazen, Jeffrey M ^b  

^a KAROLINSKA INSTITUTE   (Sweden)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; GLUCOCORTICOID; LEUKOTRIENE RECEPTOR BLOCKING AGENT; LONG ACTING DRUG; MONTELUKAST; PLACEBO; ZAFIRLUKAST; ANTIASTHMATIC AGENT; BETA ADRENERGIC RECEPTOR STIMULATING AGENT;

ASTHMA; BONE GROWTH; CLINICAL PRACTICE; DISEASE CONTROL; EDITORIAL; HUMAN; LUNG FUNCTION; PRACTICE GUIDELINE; PRIORITY JOURNAL; SIDE EFFECT; UNITED KINGDOM; DRUG COMBINATION; INHALATIONAL DRUG ADMINISTRATION; NOTE; ORAL DRUG ADMINISTRATION; RANDOMIZED CONTROLLED TRIAL (TOPIC);

ADMINISTRATION, INHALATION; ADMINISTRATION, ORAL; ADRENERGIC BETA-AGONISTS; ANTI-ASTHMATIC AGENTS; ASTHMA; DRUG THERAPY, COMBINATION; GLUCOCORTICOIDS; HUMANS; LEUKOTRIENE ANTAGONISTS; PRACTICE GUIDELINES AS TOPIC; RANDOMIZED CONTROLLED TRIALS AS TOPIC;

EID: 79955714713     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJMe1100937     Document Type: Editorial

References (10)

1. Herland K, Akselsen JP, Skjønsberg OH, Bjermer L. How representative are clinical study patients with asthma or COPD for a larger "real life" population of patients with obstructive lung disease? Respir Med 2005;99:11-9. (Pubitemid 40017378)
2. Price D, Musgrave SD, Shepstone L, et al. Leukotriene antagonists as first-line or add-on asthma-controller therapy. N Engl J Med 2011;364:1695-707.
3. Dahlén S-E. Treatment of asthma with antileukotrienes: first line or last resort therapy? Eur J Pharmacol 2006;533:40-56. (Pubitemid 43348343)
4. Ware JH, Hamel MB. Pragmatic trials -guides to better patient care? N Engl J Med 2011;364:1685-7.
5. Pedersen S, Agertoft L, Williams-Herman D, et al. Placebocontrolled study of montelukast and budesonide on short-term growth in pre-pubertal asthmatic children. Pediatr Pulmonol 2007;42:838-43. (Pubitemid 47580811)
6. Kazani S, Ware JH, Drazen JM, Taylor DR, Sears MR. The safety of long-acting beta agonists: more evidence is needed. Respirology 2010;15:881-5.
7. Roquet A, Dahlén B, Kumlin M, et al. Combined antagonism of leukotrienes and histamine produces predominant inhibition of allergen-induced early and late phase airway obstruction in asthmatics. Am J Respir Crit Care Med 1997;155:1856-63. (Pubitemid 27256109)
8. Davis BE, Illamperuma C, Gauvreau GM, et al. Single-dose desloratadine and montelukast and allergen-induced late airway responses. Eur Respir J 2009;33:1302-8.
9. Barnes N, Pavord I, Chuchalin A, et al. A randomised, double-blind, placebo-controlled study of the CRTH2 antagonist OC000459 on moderate persistent asthma. Eur Respir J 2009; 34:Suppl:564-5.
10. Wenzel S, Wilbraham D, Fuller R, Getz EB, Longphre M. Effect of an interleukin-4 variant on late phase asthmatic response to allergen challenge in asthmatic patients: results of two phase 2a studies. Lancet 2007;370:1422-31. (Pubitemid 47576168)