Biosynthesis of the 22nd genetically encoded amino acid pyrrolysine: Structure and reaction mechanism of PylC at 1.5 Å resolution

Journal of Molecular Biology

Volumn 424, Issue 5, 2012, Pages 270-282

  Quitterer, Felix ^a   List, Anja ^a   Beck, Philipp ^a   Bacher, Adelbert ^a   Groll, Michael ^a  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

amino acid; ATP grasp enzyme; biosynthesis of pyrrolysine; isopeptide bond formation; X ray crystallography

Indexed keywords

ADENINE NUCLEOTIDE; ADENOSINE DIPHOSPHATE; ADENYLYLIMIDODIPHOSPHATE; AMINO ACID; CARBONIC ACID; ENZYME; ENZYME PYRROLYSINEC; LYSINE; MAGNESIUM ION; ORNITHINE; PHOSPHATE; PYRROLYSINE; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; BIOSYNTHESIS; CARBOXY TERMINAL SEQUENCE; CATALYSIS; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME MECHANISM; ENZYME STRUCTURE; ENZYME SUBSTRATE COMPLEX; GENETIC CODE; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN STABILITY;

EID: 84869228168     PISSN: 00222836     EISSN: 10898638     Source Type: Journal    
DOI: 10.1016/j.jmb.2012.09.007     Document Type: Article

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