PurT-encoded glycinamide ribonucleotide transformylase. Accommodation of adenosine nucleotide analogs within the active site

Journal of Biological Chemistry

Volumn 277, Issue 26, 2002, Pages 23898-23908

  Thoden, James B ^a   Firestine, Steven M ^b   Benkovic, Stephen J ^c   Holden, Hazel M ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b DUQUESNE UNIVERSITY   (United States)

^c PENNSYLVANIA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOSYNTHESIS; CATALYSIS; ENCODING (SYMBOLS); ENZYMES; ESCHERICHIA COLI; X RAY DIFFRACTION ANALYSIS;

LIGANDS;

BIOCHEMISTRY;

ADENOSINE DERIVATIVE; ADENOSINE DIPHOSPHATE MAGNESIUM; ADENOSINE NUCLEOTIDE DERIVATIVE; ADENOSINE TRIPHOSPHATE MAGNESIUM; ADENOSINE TRIPHOSPHATE MAGNESIUM GAMMA S; BIOTIN CARBOXYLASE; CARBAMOYL PHOSPHATE SYNTHASE; CARBOXYLASE; FORMIC ACID; GLYCINE; LIGAND; LYSINE; MAGNESIUM 5' ADENYLYLIMIDODIPHOSPHATE; MAGNESIUM BETA,GAMMA METHYLENEADENOSINE 5' TRIPHOSPHATE; NUCLEOTIDE; NUCLEOTIDE DERIVATIVE; PHOSPHORIBOSYLGLYCINAMIDE FORMYLTRANSFERASE; PURT TRANSFORMYLASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; CATALYSIS; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME ANALYSIS; ENZYME CONFORMATION; ESCHERICHIA COLI; NONHUMAN; OPTICAL RESOLUTION; PRIORITY JOURNAL; PROTEIN MOTIF; PROTEIN STRUCTURE; PURINE SYNTHESIS; X RAY DIFFRACTION;

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; ADENYLYL IMIDODIPHOSPHATE; BINDING SITES; CRYSTALLIZATION; CRYSTALLOGRAPHY, X-RAY; HYDROXYMETHYL AND FORMYL TRANSFERASES; PHOSPHORIBOSYLGLYCINAMIDE FORMYLTRANSFERASE;

ANIMALIA; ESCHERICHIA COLI; NEGIBACTERIA;

EID: 0037189553     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M202251200     Document Type: Article

References (22)