Osteopontin Level in Synovial Fluid Is Associated with the Severity of Joint Pain and Cartilage Degradation after Anterior Cruciate Ligament Rupture

PLoS ONE

Volumn 7, Issue 11, 2012, Pages

  Yamaga, Mika ^a   Tsuji, Kunikazu ^a   Miyatake, Kazumasa ^a   Yamada, Jun ^a   Abula, Kahaer ^a   Ju, Young Jin ^a   Sekiya, Ichiro ^a   Muneta, Takeshi ^a  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

C REACTIVE PROTEIN; OSTEOPONTIN;

AMINO TERMINAL SEQUENCE; ANTERIOR CRUCIATE LIGAMENT RUPTURE; ARTHRALGIA; ARTHROSCOPY; ARTICLE; ARTICULAR CARTILAGE; CARTILAGE DEGENERATION; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE SEVERITY; ENZYME KINETICS; ENZYME LINKED IMMUNOSORBENT ASSAY; HOMEOSTASIS; HUMAN; HUMAN TISSUE; PROTEIN DEGRADATION; QUANTITATIVE ANALYSIS; SYNOVIAL FLUID LEVEL; VISUAL ANALOG SCALE;

ADOLESCENT; ADULT; ANTERIOR CRUCIATE LIGAMENT; ARTHRALGIA; ARTHROSCOPY; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMANS; MALE; MIDDLE AGED; OSTEOARTHRITIS; OSTEOPONTIN; STATISTICS, NONPARAMETRIC; SYNOVIAL FLUID;

EID: 84869221078     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0049014     Document Type: Article

References (38)

1. (CDC) CfDCaP (2009) Prevalence and most common causes of disability among adults-United States, 2005. MMWR Morb Mortal Wkly Rep 58: 421-426.
2. Muraki S, Akune T, Oka H, En-yo Y, Yoshida M, et al. (2010) Association of radiographic and symptomatic knee osteoarthritis with health-related quality of life in a population-based cohort study in Japan: the ROAD study. Osteoarthritis Cartilage 18: 1227-1234.
3. Kon E, Filardo G, Drobnic M, Madry H, Jelic M, et al. (2011) Non-surgical management of early knee osteoarthritis. Knee Surg Sports Traumatol Arthrosc.
4. Mitchell PG, Magna HA, Reeves LM, Lopresti-Morrow LL, Yocum SA, et al. (1996) Cloning, expression, and type II collagenolytic activity of matrix metalloproteinase-13 from human osteoarthritic cartilage. J Clin Invest 97: 761-768.
5. Reboul P, Pelletier JP, Tardif G, Cloutier JM, Martel-Pelletier J, (1996) The new collagenase, collagenase-3, is expressed and synthesized by human chondrocytes but not by synoviocytes. A role in osteoarthritis. J Clin Invest 97: 2011-2019.
6. Knäuper V, Will H, López-Otin C, Smith B, Atkinson SJ, et al. (1996) Cellular mechanisms for human procollagenase-3 (MMP-13) activation. Evidence that MT1-MMP (MMP-14) and gelatinase a (MMP-2) are able to generate active enzyme. J Biol Chem 271: 17124-17131.
7. Nagase H, Kashiwagi M, (2003) Aggrecanases and cartilage matrix degradation. Arthritis Res Ther 5: 94-103.
8. Pullig O, Weseloh G, Gauer S, Swoboda B, (2000) Osteopontin is expressed by adult human osteoarthritic chondrocytes: protein and mRNA analysis of normal and osteoarthritic cartilage. Matrix Biol 19: 245-255.
9. Attur MG, Dave MN, Stuchin S, Kowalski AJ, Steiner G, et al. (2001) Osteopontin: an intrinsic inhibitor of inflammation in cartilage. Arthritis Rheum 44: 578-584.
10. Huh YH, Ryu JH, Shin S, Lee DU, Yang S, et al. (2009) Esophageal cancer related gene 4 (ECRG4) is a marker of articular chondrocyte differentiation and cartilage destruction. Gene 448: 7-15.
11. Johansen JS, Hvolris J, Hansen M, Backer V, Lorenzen I, et al. (1996) Serum YKL-40 levels in healthy children and adults. Comparison with serum and synovial fluid levels of YKL-40 in patients with osteoarthritis or trauma of the knee joint. Br J Rheumatol 35: 553-559.
12. Steck E, Breit S, Breusch SJ, Axt M, Richter W, (2002) Enhanced expression of the human chitinase 3-like 2 gene (YKL-39) but not chitinase 3-like 1 gene (YKL-40) in osteoarthritic cartilage. Biochem Biophys Res Commun 299: 109-115.
13. Wang KX, Denhardt DT, (2008) Osteopontin: role in immune regulation and stress responses. Cytokine Growth Factor Rev 19: 333-345.
14. Franzén A, Heinegård D, (1985) Isolation and characterization of two sialoproteins present only in bone calcified matrix. Biochem J 232: 715-724.
15. Patarca R, Freeman GJ, Singh RP, Wei FY, Durfee T, et al. (1989) Structural and functional studies of the early T lymphocyte activation 1 (Eta-1) gene. Definition of a novel T cell-dependent response associated with genetic resistance to bacterial infection. J Exp Med 170: 145-161.
16. Patarca R, Saavedra RA, Cantor H, (1993) Molecular and cellular basis of genetic resistance to bacterial infection: the role of the early T-lymphocyte activation-1/osteopontin gene. Crit Rev Immunol 13: 225-246.
17. Bayless KJ, Davis GE, (2001) Identification of dual alpha 4beta1 integrin binding sites within a 38 amino acid domain in the N-terminal thrombin fragment of human osteopontin. J Biol Chem 276: 13483-13489.
18. Yokosaki Y, Matsuura N, Sasaki T, Murakami I, Schneider H, et al. (1999) The integrin alpha(9)beta(1) binds to a novel recognition sequence (SVVYGLR) in the thrombin-cleaved amino-terminal fragment of osteopontin. J Biol Chem 274: 36328-36334.
19. Gao YA, Agnihotri R, Vary CP, Liaw L, (2004) Expression and characterization of recombinant osteopontin peptides representing matrix metalloproteinase proteolytic fragments. Matrix Biol 23: 457-466.
20. Maeda K, Takahashi K, Takahashi F, Tamura N, Maeda M, et al. (2001) Distinct roles of osteopontin fragments in the development of the pulmonary involvement in sarcoidosis. Lung 179: 279-291.
21. Hasegawa M, Nakoshi Y, Iino T, Sudo A, Segawa T, et al. (2009) Thrombin-cleaved osteopontin in synovial fluid of subjects with rheumatoid arthritis. J Rheumatol 36: 240-245.
22. Hasegawa M, Segawa T, Maeda M, Yoshida T, Sudo A, (2011) Thrombin-cleaved osteopontin levels in synovial fluid correlate with disease severity of knee osteoarthritis. J Rheumatol 38: 129-134.
23. Rodan GA, (1995) Osteopontin overview. Ann N Y Acad Sci 760: 1-5.
24. Senger DR, Ledbetter SR, Claffey KP, Papadopoulos-Sergiou A, Peruzzi CA, et al. (1996) Stimulation of endothelial cell migration by vascular permeability factor/vascular endothelial growth factor through cooperative mechanisms involving the alphavbeta3 integrin, osteopontin, and thrombin. Am J Pathol 149: 293-305.
25. Agnihotri R, Crawford HC, Haro H, Matrisian LM, Havrda MC, et al. (2001) Osteopontin, a novel substrate for matrix metalloproteinase-3 (stromelysin-1) and matrix metalloproteinase-7 (matrilysin). J Biol Chem 276: 28261-28267.
26. Jain S, Chakraborty G, Kundu GC, (2006) The crucial role of cyclooxygenase-2 in osteopontin-induced protein kinase C alpha/c-Src/IkappaB kinase alpha/beta-dependent prostate tumor progression and angiogenesis. Cancer Res 66: 6638-6648.
27. O'Regan A, Berman JS, (2000) Osteopontin: a key cytokine in cell-mediated and granulomatous inflammation. Int J Exp Pathol 81: 373-390.
28. Matsui Y, Iwasaki N, Kon S, Takahashi D, Morimoto J, et al. (2009) Accelerated development of aging-associated and instability-induced osteoarthritis in osteopontin-deficient mice. Arthritis Rheum 60: 2362-2371.
29. Yumoto K, Ishijima M, Rittling SR, Tsuji K, Tsuchiya Y, et al. (2002) Osteopontin deficiency protects joints against destruction in anti-type II collagen antibody-induced arthritis in mice. Proc Natl Acad Sci U S A 99: 4556-4561.
30. Louboutin H, Debarge R, Richou J, Selmi TA, Donell ST, et al. (2009) Osteoarthritis in patients with anterior cruciate ligament rupture: a review of risk factors. Knee 16: 239-244.
31. Li RT, Lorenz S, Xu Y, Harner CD, Fu FH, et al. (2011) Predictors of radiographic knee osteoarthritis after anterior cruciate ligament reconstruction. Am J Sports Med 39: 2595-2603.
32. Asano H, Muneta T, Ikeda H, Yagishita K, Kurihara Y, et al. (2004) Arthroscopic evaluation of the articular cartilage after anterior cruciate ligament reconstruction: a short-term prospective study of 105 patients. Arthroscopy 20: 474-481.
33. Denhardt DT, Noda M (1998) Osteopontin expression and function: role in bone remodeling. J Cell Biochem Suppl 30-31: 92-102.
34. Xu G, Sun W, He D, Wang L, Zheng W, et al. (2005) Overexpression of osteopontin in rheumatoid synovial mononuclear cells is associated with joint inflammation, not with genetic polymorphism. J Rheumatol 32: 410-416.
35. Courtney P, Doherty M, (2009) Joint aspiration and injection and synovial fluid analysis. Best Pract Res Clin Rheumatol 23: 161-192.
36. Mori N, Majima T, Iwasaki N, Kon S, Miyakawa K, et al. (2007) The role of osteopontin in tendon tissue remodeling after denervation-induced mechanical stress deprivation. Matrix Biol 26: 42-53.
37. Toma CD, Ashkar S, Gray ML, Schaffer JL, Gerstenfeld LC, (1997) Signal transduction of mechanical stimuli is dependent on microfilament integrity: identification of osteopontin as a mechanically induced gene in osteoblasts. J Bone Miner Res 12: 1626-1636.
38. Dunn WR, Spindler KP, Amendola A, Andrish JT, Kaeding CC, et al. (2010) Which preoperative factors, including bone bruise, are associated with knee pain/symptoms at index anterior cruciate ligament reconstruction (ACLR)? A Multicenter Orthopaedic Outcomes Network (MOON) ACLR Cohort Study. Am J Sports Med 38: 1778-1787.