Esophageal cancer related gene 4 (ECRG4) is a marker of articular chondrocyte differentiation and cartilage destruction

Gene

Volumn 448, Issue 1, 2009, Pages 7-15

  Huh, Yun Hyun ^a   Ryu, Je Hwang ^a   Shin, Sun ^a   Lee, Dong Uk ^a   Yang, Siyoung ^a   Oh, Kyung Shin ^a   Chun, Churl Hong ^b   Choi, Jeong Keun ^a   Song, Woo Keun ^a   Chun, Jang Soo ^a  

^a Cell Dynamics Research Center   (South Korea)

^b Wonkwang University School of Medicine   (South Korea)

Author keywords

Articular cartilage; Chondrocytes; Collagen II; ECRG4; Osteoarthritis

Indexed keywords

ESOPHAGEAL CANCER RELATED GENE 4; GENE PRODUCT; INTERLEUKIN 1BETA; UNCLASSIFIED DRUG;

ADULT; AGED; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; ARTICULAR CARTILAGE; CARTILAGE CELL; CARTILAGE DEGENERATION; CELL DIFFERENTIATION; CELL PROLIFERATION; CHONDROGENESIS; CONTROLLED STUDY; EMBRYO; EXPRESSED SEQUENCE TAG; EXTRACELLULAR MATRIX; GENETIC REGULATION; HUMAN; HUMAN TISSUE; IN VITRO STUDY; LIMB BUD; MESENCHYME CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SECRETION; TISSUE SPECIFICITY; TRANSGENIC MOUSE;

ANIMALS; BIOLOGICAL MARKERS; BONE DEVELOPMENT; CARTILAGE; CELL DIFFERENTIATION; CELLS, CULTURED; CHONDROCYTES; CHONDROGENESIS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; LIMB BUDS; MICE; NEOPLASM PROTEINS; ORGAN SPECIFICITY;

MUS MUSCULUS;

EID: 70349782350     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.gene.2009.08.015     Document Type: Article

References (24)

1. Altman R., et al. Development of criteria for the classification and reporting of osteoarthritis. Classification of osteoarthritis of the knee. Diagnostic and Therapeutic Criteria Committee of the American Rheumatism Association. Arthritis Rheum. 29 (1986) 1039-1049
2. Blom A.B., et al. Crucial role of macrophages in matrix metalloproteinase-mediated cartilage destruction during experimental osteoarthritis: involvement of matrix metalloproteinase 3. Arthritis Rheum. 56 (2007) 147-157
3. DeLise A.M., Fischer L., and Tuan R.S. Cellular interactions and signaling in cartilage development. Osteoarthritis Cartilage 8 (2000) 309-334
4. Fukumoto T., et al. Combined effects of insulin-like growth factor-1 and transforming growth factor-beta1 on periosteal mesenchymal cells during chondrogenesis in vitro. Osteoarthritis Cartilage 11 (2003) 55-64
5. Goldring M.B., Tsuchimochi K., and Ijiri K. The control of chondrogenesis. J. Cell. Biochem. 97 (2006) 33-44
6. Gouttenoire J., Valcourt U., Ronzière M.C., Aubert-Foucher E., Mallein-Gerin F., and Herbage D. Modulation of collagen synthesis in normal and osteoarthritic cartilage. Biorheology 41 (2004) 535-542
7. Hong S., et al. Identification and integrative analysis of 28 novel genes specifically expressed and developmentally regulated in murine spermatogenic cells. J. Biol. Chem. 280 (2005) 7685-7693
8. Huh Y.H., Ryu J.H., and Chun J.S. Regulation of type II collagen expression by histone deacetylase in articular chondrocytes. J. Biol. Chem. 282 (2007) 17123-17131
9. Kim J.S., Ryoo Z.Y., and Chun J.S. Cytokine-like 1 (CYTL1) regulates the chondrogenesis of mesenchymal cells. J. Biol. Chem. 282 (2008) 29359-29367
10. Li L.W., et al. Expression of esophageal cancer related gene 4 (ECRG4), a novel tumor suppressor gene, in esophageal cancer and its inhibitory effect on the tumor growth in vitro. Int. J. cancer. 125 (2009) 1505-1513
11. Liu X., Rapp N., Deans R., and Cheng L. Molecular cloning and chromosomal mapping of a candidate cytokine gene selectively expressed in human CD34+ cells. Genomics 65 (2000) 283-292
12. Malemud C.J. Fundamental pathways in osteoarthritis: overview. Frontiers Biosci. 4 (1999) d659-d661
13. Mankin H.J., Dorfman H., Lippiello L., and Zarins A. Biochemical and metabolic abnormalities in articular cartilage from osteo-arthritic human hips. II. Correlation of morphology with biochemical and metabolic data. J. Bone Jt. Surg. Am. 53 (1971) 523-537
14. Mariani F.V., and Martin G.R. Deciphering skeletal patterning: clues from the limb. Nature 423 (2003) 319-325
15. Mello M.A., and Tuan R.S. High density micromass cultures of embryonic limb bud mesenchymal cells: an in vitro model of endochondral skeletal development. In Vitro Cell Dev. Biol. Anim. 35 (1999) 262-269
16. Oh C.D., and Chun J.S. Signaling mechanisms leading to the regulation of differentiation and apoptosis of articular chondrocytes by insulin-like growth factor-1. J. Biol. Chem. 278 (2003) 36563-36571
17. Peale Jr. F.V., and Gerritsen M.E. Gene profiling techniques and their application in angiogenesis and vascular development. J. Pathol. 195 (2001) 7-19
18. Ryu J.H., and Chun J.S. Opposing roles of WNT-5A and WNT-11 in interleukin-1beta regulation of type II collagen expression in articular chondrocytes. J. Biol. Chem. 281 (2006) 22039-22047
19. Steck E., Breit S., Breusch S.J., Axtm M., and Richter W. Enhanced expression of the human chitinase 3-like 2 gene (YKL-39) but not chitinase 3-like 1 gene (YKL-40) in osteoarthritic cartilage. Biochem. Biophys. Res. Commun. 299 (2002) 109-115
20. Su T., Liu H., and Lu S. Cloning and identification of cDNA fragments related to human esophageal cancer. Zhonghua Zhong Liu Za Zhi 20 (1998) 254-257
21. Tickle C. Molecular basis of vertebrate limb patterning. Am. J. Med. Genet. 112 (2002) 250-255
22. Ueta C., et al. Skeletal malformations caused by overexpression of Cbfa1 or its dominant negative form in chondrocytes. J. Cell Biol. 153 (2001) 87-100
23. Vanaja D.K., et al. Hypermethylation of genes for diagnosis and risk stratification of prostate cancer. Cancer Invest 27 (2009) 549-560
24. Yoon Y.M., et al. Maintenance of differentiated phenotype of articular chondrocytes by protein kinase C and extracellular signal-regulated protein kinase. J. Biol. Chem. 277 (2002) 8412-8420