Differential effects of nicotine treatment and ethanol self-administration on CYP2A6, CYP2B6 and nicotine pharmacokinetics in African green monkeys

Journal of Pharmacology and Experimental Therapeutics

Volumn 343, Issue 3, 2012, Pages 628-637

  Ferguson, C S ^a   Miksys, S ^a   Palmour, R M ^b   Tyndale, Rachel F ^a  

^a UNIVERSITY OF TORONTO   (Canada)

^b MCGILL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL; AMFEBUTAMONE; COTININE; COUMARIN; CYTOCHROME P450 2A6; CYTOCHROME P450 2B6; MESSENGER RNA; NICOTINE;

ALCOHOL CONSUMPTION; ANIMAL EXPERIMENT; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; CHEMICAL MODIFICATION; CHLOROCEBUS; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME REGULATION; HALF LIFE TIME; IN VITRO STUDY; IN VIVO STUDY; LIVER EXAMINATION; LIVER MICROSOME METABOLISM; MALE; MAXIMUM PLASMA CONCENTRATION; MOLECULAR INTERACTION; NONHUMAN; OXIDATION; PRIORITY JOURNAL; RNA ANALYSIS; XENOBIOTIC METABOLISM;

ANIMALS; ARYL HYDROCARBON HYDROXYLASES; CERCOPITHECUS AETHIOPS; COTININE; DRUG INTERACTIONS; ETHANOL; HALF-LIFE; LIVER; MALE; MICROSOMES, LIVER; NICOTINE; OXIDOREDUCTASES, N-DEMETHYLATING; SELF ADMINISTRATION; TISSUE DISTRIBUTION;

EID: 84869219873     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.112.198564     Document Type: Article

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