-
1
-
-
1242331823
-
Is Alzheimer's disease a neurodegenerative or a vascular disorder? Data, dogma, and dialectics
-
de la Torre JC, (2004) Is Alzheimer's disease a neurodegenerative or a vascular disorder? Data, dogma, and dialectics. Lancet Neurol 3: 184-190.
-
(2004)
Lancet Neurol
, vol.3
, pp. 184-190
-
-
de la Torre, J.C.1
-
2
-
-
0028945660
-
Evidence that A beta 42 is the real culprit in Alzheimer's disease
-
Younkin SG, (1995) Evidence that A beta 42 is the real culprit in Alzheimer's disease. Ann Neurol 37: 287-288.
-
(1995)
Ann Neurol
, vol.37
, pp. 287-288
-
-
Younkin, S.G.1
-
3
-
-
16044373524
-
Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease
-
Scheuner D, Eckman C, Jensen M, Song X, Citron M, et al. (1996) Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease. Nat Med 2: 864-870.
-
(1996)
Nat Med
, vol.2
, pp. 864-870
-
-
Scheuner, D.1
Eckman, C.2
Jensen, M.3
Song, X.4
Citron, M.5
-
4
-
-
0033975837
-
Plasma and cerebrospinal fluid levels of amyloid beta proteins 1-40 and 1-42 in Alzheimer disease
-
Mehta PD, Pirttilä T, Mehta SP, Sersen EA, Aisen PS, et al. (2000) Plasma and cerebrospinal fluid levels of amyloid beta proteins 1-40 and 1-42 in Alzheimer disease. Arch Neurol. 57: 100-105.
-
(2000)
Arch Neurol
, vol.57
, pp. 100-105
-
-
Mehta, P.D.1
Pirttilä, T.2
Mehta, S.P.3
Sersen, E.A.4
Aisen, P.S.5
-
5
-
-
33745959062
-
Plasma Abeta(1-40) and Abeta(1-42) and the risk of dementia: a prospective case-cohort study
-
van Oijen M, Hofman A, Soares HD, Koudstaal PJ, Breteler MM, (2006) Plasma Abeta(1-40) and Abeta(1-42) and the risk of dementia: a prospective case-cohort study. Lancet Neurol 5: 655-660.
-
(2006)
Lancet Neurol
, vol.5
, pp. 655-660
-
-
van Oijen, M.1
Hofman, A.2
Soares, H.D.3
Koudstaal, P.J.4
Breteler, M.M.5
-
6
-
-
33947282076
-
Association of low plasma Abeta42/Abeta40 ratios with increased imminent risk for mild cognitive impairment and Alzheimer disease
-
Graff-Radford NR, Crook JE, Lucas J, Boeve BF, Knopman DS, et al. (2007) Association of low plasma Abeta42/Abeta40 ratios with increased imminent risk for mild cognitive impairment and Alzheimer disease. Arch Neurol. 64: 354-362.
-
(2007)
Arch Neurol
, vol.64
, pp. 354-362
-
-
Graff-Radford, N.R.1
Crook, J.E.2
Lucas, J.3
Boeve, B.F.4
Knopman, D.S.5
-
7
-
-
0030609125
-
Abeta25-35 induces rapid lysis of red blood cells: contrast with Abeta1-42 and examination of underlying mechanisms
-
Mattson MP, Begley JG, Mark RJ, Furukawa K, (1997) Abeta25-35 induces rapid lysis of red blood cells: contrast with Abeta1-42 and examination of underlying mechanisms. Brain Res 771: 147-153.
-
(1997)
Brain Res
, vol.771
, pp. 147-153
-
-
Mattson, M.P.1
Begley, J.G.2
Mark, R.J.3
Furukawa, K.4
-
8
-
-
84934440941
-
Do red blood cell-beta-amyloid interactions alter oxygen delivery in Alzheimer's disease
-
Mohanty JG, Eckley DM, Williamson JD, Launer LJ, Rifkind JM, (2008) Do red blood cell-beta-amyloid interactions alter oxygen delivery in Alzheimer's disease? Adv Exp Med Biol 614: 29-35.
-
(2008)
Adv Exp Med Biol
, vol.614
, pp. 29-35
-
-
Mohanty, J.G.1
Eckley, D.M.2
Williamson, J.D.3
Launer, L.J.4
Rifkind, J.M.5
-
9
-
-
79954435392
-
Amyloid β-induced erythrocytic damage and its attenuation by carotenoids
-
Nakagawa K, Kiko T, Miyazawa T, Sookwong P, Tsuduki T, et al. (2011) Amyloid β-induced erythrocytic damage and its attenuation by carotenoids. FEBS Lett 585: 1249-1254.
-
(2011)
FEBS Lett
, vol.585
, pp. 1249-1254
-
-
Nakagawa, K.1
Kiko, T.2
Miyazawa, T.3
Sookwong, P.4
Tsuduki, T.5
-
10
-
-
0038095183
-
Red cell perturbations by amyloid beta-protein
-
Jayakumar R, Kusiak JW, Chrest FJ, Demehin AA, Murali J, et al. (2003) Red cell perturbations by amyloid beta-protein. Biochim Biophys Acta 1622: 20-28.
-
(2003)
Biochim Biophys Acta
, vol.1622
, pp. 20-28
-
-
Jayakumar, R.1
Kusiak, J.W.2
Chrest, F.J.3
Demehin, A.A.4
Murali, J.5
-
11
-
-
80054959119
-
Amyloid β induces adhesion of erythrocytes to endothelial cells and affects endothelial viability and functionality
-
Nakagawa K, Kiko T, Kuriwada S, Miyazawa T, Kimura F, et al. (2011) Amyloid β induces adhesion of erythrocytes to endothelial cells and affects endothelial viability and functionality. Biosci Biotechnol Biochem 75: 2030-2033.
-
(2011)
Biosci Biotechnol Biochem
, vol.75
, pp. 2030-2033
-
-
Nakagawa, K.1
Kiko, T.2
Kuriwada, S.3
Miyazawa, T.4
Kimura, F.5
-
12
-
-
79958768730
-
Antioxidant effect of astaxanthin on phospholipid peroxidation in human erythrocytes
-
Nakagawa K, Kiko T, Miyazawa T, Carpentero Burdeos G, Kimura F, et al. (2011) Antioxidant effect of astaxanthin on phospholipid peroxidation in human erythrocytes. Br J Nutr 105: 1563-1571.
-
(2011)
Br J Nutr
, vol.105
, pp. 1563-1571
-
-
Nakagawa, K.1
Kiko, T.2
Miyazawa, T.3
Carpentero Burdeos, G.4
Kimura, F.5
-
13
-
-
84863232523
-
Significance of lutein in red blood cells of Alzheimer's disease patients
-
Kiko T, Nakagawa K, Tsuduki T, Suzuki T, Arai H, et al. (2012) Significance of lutein in red blood cells of Alzheimer's disease patients. J Alzheimers Dis. 28: 593-600.
-
(2012)
J Alzheimers Dis
, vol.28
, pp. 593-600
-
-
Kiko, T.1
Nakagawa, K.2
Tsuduki, T.3
Suzuki, T.4
Arai, H.5
-
14
-
-
73349122343
-
Antioxidant effect of lutein towards phospholipid hydroperoxidation in human erythrocytes
-
Nakagawa K, Kiko T, Hatade K, Sookwong P, Arai H, et al. (2009) Antioxidant effect of lutein towards phospholipid hydroperoxidation in human erythrocytes. Br J Nutr 102: 1280-1284.
-
(2009)
Br J Nutr
, vol.102
, pp. 1280-1284
-
-
Nakagawa, K.1
Kiko, T.2
Hatade, K.3
Sookwong, P.4
Arai, H.5
-
15
-
-
49049092325
-
Development of an HPLC-based assay for carotenoids in human red blood cells: application to clinical studies
-
Nakagawa K, Kiko T, Hatade K, Asai A, Kimura F, et al. (2008) Development of an HPLC-based assay for carotenoids in human red blood cells: application to clinical studies. Anal Biochem 381: 129-134.
-
(2008)
Anal Biochem
, vol.381
, pp. 129-134
-
-
Nakagawa, K.1
Kiko, T.2
Hatade, K.3
Asai, A.4
Kimura, F.5
-
16
-
-
0026740745
-
Chemiluminescent simultaneous determination of phosphatidylcholine hydroperoxide and phosphatidylethanolamine hydroperoxide in the liver and brain of the rat
-
Miyazawa T, Suzuki T, Fujimoto K, Yasuda K, (1992) Chemiluminescent simultaneous determination of phosphatidylcholine hydroperoxide and phosphatidylethanolamine hydroperoxide in the liver and brain of the rat. J Lipid Res 33: 1051-1059.
-
(1992)
J Lipid Res
, vol.33
, pp. 1051-1059
-
-
Miyazawa, T.1
Suzuki, T.2
Fujimoto, K.3
Yasuda, K.4
-
17
-
-
0031729335
-
Quantification of modified amyloid beta peptides in Alzheimer disease and Down syndrome brains
-
Hosoda R, Saido TC, Otvos L Jr, Arai T, Mann DM, et al. (1998) Quantification of modified amyloid beta peptides in Alzheimer disease and Down syndrome brains. J Neuropathol Exp Neurol 57: 1089-1095.
-
(1998)
J Neuropathol Exp Neurol
, vol.57
, pp. 1089-1095
-
-
Hosoda, R.1
Saido, T.C.2
Otvos Jr., L.3
Arai, T.4
Mann, D.M.5
-
18
-
-
0030293676
-
Familial Alzheimer's disease-linked presenilin 1 variants elevate Abeta1-42/1-40 ratio in vitro and in vivo
-
Borchelt DR, Thinakaran G, Eckman CB, Lee MK, Davenport F, et al. (1996) Familial Alzheimer's disease-linked presenilin 1 variants elevate Abeta1-42/1-40 ratio in vitro and in vivo. Neuron 17: 1005-1013.
-
(1996)
Neuron
, vol.17
, pp. 1005-1013
-
-
Borchelt, D.R.1
Thinakaran, G.2
Eckman, C.B.3
Lee, M.K.4
Davenport, F.5
-
19
-
-
84863167950
-
Cerebrospinal fluid Aβ and tau level fluctuation in an older clinical cohort
-
Moghekar A, Goh J, Li M, Albert M, O'Brien RJ, (2012) Cerebrospinal fluid Aβ and tau level fluctuation in an older clinical cohort. Arch Neurol 69: 246-250.
-
(2012)
Arch Neurol
, vol.69
, pp. 246-250
-
-
Moghekar, A.1
Goh, J.2
Li, M.3
Albert, M.4
O'Brien, R.J.5
-
20
-
-
0028322017
-
An increased percentage of long amyloid beta protein secreted by familial amyloid beta protein precursor (beta APP717) mutants
-
Suzuki N, Cheung TT, Cai XD, Odaka A, Otvos L Jr, et al. (1994) An increased percentage of long amyloid beta protein secreted by familial amyloid beta protein precursor (beta APP717) mutants. Science 264: 1336-1340.
-
(1994)
Science
, vol.264
, pp. 1336-1340
-
-
Suzuki, N.1
Cheung, T.T.2
Cai, X.D.3
Odaka, A.4
Otvos Jr., L.5
-
21
-
-
0242412140
-
Plasma A[beta]40 and A[beta]42 and Alzheimer's disease: relation to age, mortality, and risk
-
Mayeux R, Honig LS, Tang MX, Manly J, Stern Y, et al. (2003) Plasma A[beta]40 and A[beta]42 and Alzheimer's disease: relation to age, mortality, and risk. Neurology 61: 1185-1190.
-
(2003)
Neurology
, vol.61
, pp. 1185-1190
-
-
Mayeux, R.1
Honig, L.S.2
Tang, M.X.3
Manly, J.4
Stern, Y.5
-
22
-
-
0035863055
-
Age-dependent changes in brain, CSF, and plasma amyloid (beta) protein in the Tg2576 transgenic mouse model of Alzheimer's disease
-
Kawarabayashi T, Younkin LH, Saido TC, Shoji M, Ashe KH, et al. (2001) Age-dependent changes in brain, CSF, and plasma amyloid (beta) protein in the Tg2576 transgenic mouse model of Alzheimer's disease. J Neurosci 21: 372-381.
-
(2001)
J Neurosci
, vol.21
, pp. 372-381
-
-
Kawarabayashi, T.1
Younkin, L.H.2
Saido, T.C.3
Shoji, M.4
Ashe, K.H.5
-
23
-
-
0030035294
-
Fate of cerebrospinal fluid-borne amyloid beta-peptide: rapid clearance into blood and appreciable accumulation by cerebral arteries
-
Ghersi-Egea JF, Gorevic PD, Ghiso J, Frangione B, Patlak CS, et al. (1996) Fate of cerebrospinal fluid-borne amyloid beta-peptide: rapid clearance into blood and appreciable accumulation by cerebral arteries. J Neurochem 67: 880-883.
-
(1996)
J Neurochem
, vol.67
, pp. 880-883
-
-
Ghersi-Egea, J.F.1
Gorevic, P.D.2
Ghiso, J.3
Frangione, B.4
Patlak, C.S.5
-
24
-
-
2542475986
-
Clearing amyloid through the blood-brain barrier
-
Zlokovic BV, (2004) Clearing amyloid through the blood-brain barrier. J Neurochem 89: 807-811.
-
(2004)
J Neurochem
, vol.89
, pp. 807-811
-
-
Zlokovic, B.V.1
-
25
-
-
78149392229
-
Peripherally applied Abeta-containing inoculates induce cerebral beta-amyloidosis
-
Eisele YS, Obermüller U, Heilbronner G, Baumann F, Kaeser SA, et al. (2010) Peripherally applied Abeta-containing inoculates induce cerebral beta-amyloidosis. Science 330: 980-982.
-
(2010)
Science
, vol.330
, pp. 980-982
-
-
Eisele, Y.S.1
Obermüller, U.2
Heilbronner, G.3
Baumann, F.4
Kaeser, S.A.5
-
26
-
-
0035902619
-
Peripheral anti-A beta antibody alters CNS and plasma A beta clearance and decreases brain A beta burden in a mouse model of Alzheimer's disease
-
DeMattos RB, Bales KR, Cummins DJ, Dodart JC, Paul SM, et al. (2001) Peripheral anti-A beta antibody alters CNS and plasma A beta clearance and decreases brain A beta burden in a mouse model of Alzheimer's disease. Proc Natl Acad Sci U S A 98: 8850-8855.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 8850-8855
-
-
DeMattos, R.B.1
Bales, K.R.2
Cummins, D.J.3
Dodart, J.C.4
Paul, S.M.5
-
27
-
-
0029100939
-
Platelets are the primary source of amyloid β-peptide in human blood
-
Chen M, Inestrosa NC, Ross GS, Fernandez HL, (1995) Platelets are the primary source of amyloid β-peptide in human blood. Biochem Biophys Res Commun 213: 96-103.
-
(1995)
Biochem Biophys Res Commun
, vol.213
, pp. 96-103
-
-
Chen, M.1
Inestrosa, N.C.2
Ross, G.S.3
Fernandez, H.L.4
-
28
-
-
0033975837
-
Plasma and cerebrospinal fluid levels of amyloid beta proteins 1-40 and 1-42 in Alzheimer disease
-
Mehta PD, Pirttilä T, Mehta SP, Sersen EA, Aisen PS, et al. (2000) Plasma and cerebrospinal fluid levels of amyloid beta proteins 1-40 and 1-42 in Alzheimer disease. Arch Neurol 57: 100-105.
-
(2000)
Arch Neurol
, vol.57
, pp. 100-105
-
-
Mehta, P.D.1
Pirttilä, T.2
Mehta, S.P.3
Sersen, E.A.4
Aisen, P.S.5
-
29
-
-
0034708137
-
Amyloid-beta peptides interact with plasma proteins and erythrocytes: implications for their quantitation in plasma
-
Kuo YM, Kokjohn TA, Kalback W, Luchrs D, Galasko DR, et al. (2000) Amyloid-beta peptides interact with plasma proteins and erythrocytes: implications for their quantitation in plasma. Biochem Biophys Res Commun 268: 750-756.
-
(2000)
Biochem Biophys Res Commun
, vol.268
, pp. 750-756
-
-
Kuo, Y.M.1
Kokjohn, T.A.2
Kalback, W.3
Luchrs, D.4
Galasko, D.R.5
-
30
-
-
0029802659
-
Fusogenic properties of the C-terminal domain of the Alzheimer beta-amyloid peptide
-
Pillot T, Goethals M, Vanloo B, Talussot C, Brasseur R, et al. (1996) Fusogenic properties of the C-terminal domain of the Alzheimer beta-amyloid peptide. J Biol Chem 271: 28757-28765.
-
(1996)
J Biol Chem
, vol.271
, pp. 28757-28765
-
-
Pillot, T.1
Goethals, M.2
Vanloo, B.3
Talussot, C.4
Brasseur, R.5
-
31
-
-
0037699792
-
Age but not diagnosis is the main predictor of plasma amyloid beta-protein levels
-
Fukumoto H, Tennis M, Locascio JJ, Hyman BT, Growdon JH, et al. (2003) Age but not diagnosis is the main predictor of plasma amyloid beta-protein levels. Arch Neurol 60: 958-964.
-
(2003)
Arch Neurol
, vol.60
, pp. 958-964
-
-
Fukumoto, H.1
Tennis, M.2
Locascio, J.J.3
Hyman, B.T.4
Growdon, J.H.5
-
32
-
-
84934440941
-
Do red blood cell-beta-amyloid interactions alter oxygen delivery in Alzheimer's disease
-
Mohanty JG, Eckley DM, Williamson JD, Launer LJ, Rifkind JM, (2008) Do red blood cell-beta-amyloid interactions alter oxygen delivery in Alzheimer's disease? Adv Exp Med Biol 614: 29-35.
-
(2008)
Adv Exp Med Biol
, vol.614
, pp. 29-35
-
-
Mohanty, J.G.1
Eckley, D.M.2
Williamson, J.D.3
Launer, L.J.4
Rifkind, J.M.5
-
33
-
-
0032946019
-
Lipoprotein-free amyloidogenic peptides in plasma are elevated in patients with sporadic Alzheimer's disease and Down's syndrome
-
Matsubara E, Ghiso J, Frangione B, Amari M, Tomidokoro Y, et al. (1999) Lipoprotein-free amyloidogenic peptides in plasma are elevated in patients with sporadic Alzheimer's disease and Down's syndrome. Ann Neurol 45: 537-541.
-
(1999)
Ann Neurol
, vol.45
, pp. 537-541
-
-
Matsubara, E.1
Ghiso, J.2
Frangione, B.3
Amari, M.4
Tomidokoro, Y.5
-
34
-
-
4544227975
-
Vitamin A exhibits potent antiamyloidogenic and fibril-destabilizing effects in vitro
-
Ono K, Yoshiike Y, Takashima A, Hasegawa K, Naiki H, et al. (2004) Vitamin A exhibits potent antiamyloidogenic and fibril-destabilizing effects in vitro. Exp Neurol 189: 380-392.
-
(2004)
Exp Neurol
, vol.189
, pp. 380-392
-
-
Ono, K.1
Yoshiike, Y.2
Takashima, A.3
Hasegawa, K.4
Naiki, H.5
-
35
-
-
81855199775
-
Vitamin A has anti-oligomerization effects on amyloid-β in vitro
-
Takasaki J, Ono K, Yoshiike Y, Hirohata M, Ikeda T, et al. (2011) Vitamin A has anti-oligomerization effects on amyloid-β in vitro. J Alzheimers Dis 27: 271-280.
-
(2011)
J Alzheimers Dis
, vol.27
, pp. 271-280
-
-
Takasaki, J.1
Ono, K.2
Yoshiike, Y.3
Hirohata, M.4
Ikeda, T.5
-
36
-
-
0037306664
-
Apolipoprotein E influences amyloid-beta clearance from the murine periphery
-
Hone E, Martins IJ, Fonte J, Martins RN, (2003) Apolipoprotein E influences amyloid-beta clearance from the murine periphery. J Alzheimers Dis 5: 1-8.
-
(2003)
J Alzheimers Dis
, vol.5
, pp. 1-8
-
-
Hone, E.1
Martins, I.J.2
Fonte, J.3
Martins, R.N.4
-
37
-
-
8544240891
-
Systemic catabolism of Alzheimer's Abeta40 and Abeta42
-
Ghiso J, Shayo M, Calero M, Ng D, Tomidokoro Y, et al. (2004) Systemic catabolism of Alzheimer's Abeta40 and Abeta42. J Biol Chem 279: 45897-45908.
-
(2004)
J Biol Chem
, vol.279
, pp. 45897-45908
-
-
Ghiso, J.1
Shayo, M.2
Calero, M.3
Ng, D.4
Tomidokoro, Y.5
-
38
-
-
8544240891
-
Systemic catabolism of Alzheimer's Abeta40 and Abeta42
-
Tamaki C, Ohtsuki S, Terasaki T, (2004) Systemic catabolism of Alzheimer's Abeta40 and Abeta42. J Biol Chem 279: 45897-45908.
-
(2004)
J Biol Chem
, vol.279
, pp. 45897-45908
-
-
Tamaki, C.1
Ohtsuki, S.2
Terasaki, T.3
-
39
-
-
0036905921
-
Amyloid beta-peptide (1-42)-induced oxidative stress and neurotoxicity: implications for neurodegeneration in Alzheimer's disease brain. A review
-
Butterfield DA, (2002) Amyloid beta-peptide (1-42)-induced oxidative stress and neurotoxicity: implications for neurodegeneration in Alzheimer's disease brain. A review. Free Radic Res 36: 1307-1313.
-
(2002)
Free Radic Res
, vol.36
, pp. 1307-1313
-
-
Butterfield, D.A.1
-
40
-
-
0032880901
-
Methionine residue 35 is important in amyloid beta-peptide-associated free radical oxidative stress
-
Varadarajan S, Yatin S, Kanski J, Jahanshahi F, Butterfield DA, (1999) Methionine residue 35 is important in amyloid beta-peptide-associated free radical oxidative stress. Brain Res Bull 50: 133-141.
-
(1999)
Brain Res Bull
, vol.50
, pp. 133-141
-
-
Varadarajan, S.1
Yatin, S.2
Kanski, J.3
Jahanshahi, F.4
Butterfield, D.A.5
|