Antioxidant effect of astaxanthin on phospholipid peroxidation in human erythrocytes

British Journal of Nutrition

Volumn 105, Issue 11, 2011, Pages 1563-1571

  Nakagawa, Kiyotaka ^a   Kiko, Takehiro ^a   Miyazawa, Taiki ^a   Carpentero Burdeos, Gregor ^a   Kimura, Fumiko ^a   Satoh, Akira ^b   Miyazawa, Teruo ^a  

^a TOHOKU UNIVERSITY   (Japan)

^b YAMAHA MOTOR CO   (Japan)

Author keywords

Astaxanthin; Dementia; Erythrocytes; Phospholipid hydroperoxides

Indexed keywords

ASTAXANTHIN; LIPID HYDROPEROXIDE; PHOSPHOLIPID HYDROPEROXIDE; PLACEBO; UNCLASSIFIED DRUG;

ADULT; AGED; ANTIOXIDANT ACTIVITY; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DIET SUPPLEMENTATION; DOSE RESPONSE; DOUBLE BLIND PROCEDURE; DRUG BLOOD LEVEL; DRUG DISTRIBUTION; DRUG DOSE COMPARISON; DRUG EFFICACY; DRUG TARGETING; FEMALE; HUMAN; HUMAN EXPERIMENT; LIPID PEROXIDATION; MALE; NORMAL HUMAN; RANDOMIZED CONTROLLED TRIAL;

AGED; CHLOROPHYTA; DOUBLE-BLIND METHOD; ERYTHROCYTES; FEMALE; HUMANS; MALE; MIDDLE AGED; OXIDATION-REDUCTION; PHOSPHOLIPIDS; PLANT OILS; XANTHOPHYLLS;

EID: 79958768730     PISSN: 00071145     EISSN: 14752662     Source Type: Journal    
DOI: 10.1017/S0007114510005398     Document Type: Article

References (26)

1. Miyazawa T, Yasuda K, Fujimoto K, et al. (1988) Presence of phosphatidylcholine hydroperoxide in human plasma. J Biochem 103, 744-746.
2. Miyazawa T, Suzuki T, Fujimoto K, et al. (1992) Chemiluminescent simultaneous determination of phosphatidylcholine hydroperoxide and phosphatidylethanolamine hydroperoxide in the liver and brain of the rat. J Lipid Res 33, 1051-1059.
3. Miyazawa T, Suzuki T, Yasuda K, et al. (1992) Accumulation of phospholipid hydroperoxides in red blood cell membranes in Alzheimer disease. In Oxygen Radicals, pp. 327-330 [K Yagi, M Kondo, E Niki and T Yoshikawa, editors]. Amsterdam: Elsevier Science Publishing.
4. Bosman GJ, Bartholomeus IG, de Man AJ, et al. (1991) Erythrocyte membrane characteristics indicate abnormal cellular aging in patients with Alzheimer's disease. Neurobiol Aging 12, 13-18.
5. Goodall HB, Reid AH, Findlay DJ, et al. (1994) Irregular distortion of the erythrocytes (acanthocytes, spur cells) in senile dementia. Dis Markers 12, 23-41. (Pubitemid 24313522)
6. Solerte SB, Ceresini G, Ferrari E, et al. (2000) Hemorheological changes and overproduction of cytokines from immune cells in mild to moderate dementia of the Alzheimer's type: adverse effects on cerebromicrovascular system. Neurobiol Aging 21, 271-281. (Pubitemid 30387085)
7. Ajmani RS, Metter EJ, Jaykumar R, et al. (2000) Hemodynamic changes during aging associated with cerebral blood flow and impaired cognitive function. Neurobiol Aging 21, 257-269. (Pubitemid 30387084)
8. Mohanty JG, Eckley DM, Williamson JD, et al. (2008) Do red blood cell-b-amyloid interactions alter oxygen delivery in Alzheimer's disease? Adv Exp Med Biol 614, 29-35.
9. Nakagawa K, Kiko T, Hatade K, et al. (2008) Development of an HPLC-based assay for carotenoids in human red blood cells: application to clinical studies. Anal Biochem 381, 129-134.
10. Nakagawa K, Miyazawa T, Kiko T, et al. (2010) Effect of carotenoids towards lipid peroxidation in vivo. J JSMUFF 6, 123-130 [in Japanese].
11. Nakagawa K, Kiko T, Hatade K, et al. (2009) Antioxidant effect of lutein towards phospholipid hydroperoxidation in human erythrocytes. Br J Nutr 102, 1280-1284.
12. Nakagawa K, Fujimoto K & Miyazawa T (1996) b-Carotene as a high-potency antioxidant to prevent the formation of phospholipid hydroperoxides in red blood cells of mice. Biochim Biophys Acta 1299, 110-116.
13. Asai A, Nakagawa K & Miyazawa T (1999) Antioxidative effects of turmeric, rosemary and capsicum extracts on membrane phospholipid peroxidation and liver lipid metabolism in mice. Biosci Biotechnol Biochem 63, 2118-2122. (Pubitemid 129549033)
14. Higuera-Ciapara I, Félix-Valenzuela L & Goycoolea FM (2006) Astaxanthin: a review of its chemistry and applications. Crit Rev Food Sci Nutr 46, 185-196.
15. Hussein G, Sankawa U, Goto H, et al. (2006) Astaxanthin, a carotenoid with potential in human health and nutrition. J Nat Prod 69, 443-449.
16. Guerin M, Huntley ME & Olaizola M (2003) Haematococcus astaxanthin: applications for human health and nutrition. Trends Biotechnol 21, 210-216. (Pubitemid 36515074)
17. Satoh A, Ishikura M, Murakami N, et al. (2010) The innovation of technology for microalgae cultivation and its application in functional foods and the nutraceutical industry. In Biotechnology in Functional Foods and Nutraceuticals, pp. 313-329 [D Bagchi, FC Lau and DK Ghosh, editors]. London: Taylor & Francis Group, CRC Press.
18. Ikeda S, Tohyama T, Yoshimura H, et al. (2003) Dietary a-tocopherol decreases a-tocotrienol but not g-tocotrienol concentration in rats. J Nutr 133, 428-434. (Pubitemid 36172895)
19. Fotouhi N, Meydani M, Santos MS, et al. (1996) Carotenoid and tocopherol concentrations in plasma, peripheral blood mononuclear cells, and red blood cells after long-term b-carotene supplementation in men. Am J Clin Nutr 63, 553-558. (Pubitemid 26099248)
20. Norkus EP, Bhagavan HN & Nair PP (1990) Relationship between individual carotenoids in plasma, platelets and red blood cells (RBC) of adult subjects. FASEB J 4, A1774.
21. Murata T, Tamai H, Morinobu T, et al. (1992) Determination of b-carotene in plasma, blood cells and buccal mucosa by electrochemical detection. Lipids 27, 840-843.
22. Miyazawa T (1989) Determination of phospholipid hydroperoxides in human blood plasma by a chemiluminescence- HPLC assay. Free Radic Biol Med 7, 209-217. (Pubitemid 19220723)
23. Moriya K, Nakagawa K, Santa T, et al. (2001) Oxidative stress in the absence of inflammation in a mouse model for hepatitis C virus-associated hepatocarcinogenesis. Cancer Res 61, 4365-4370. (Pubitemid 32685760)
24. Uchiyama A & Okada Y (2008) Clinical efficacy of astaxanthin- containing Haematococcus pluvialis extract for the volunteers at risk of metabolic syndrome. J Clin Biochem Nutr 43, 38-43.
25. Satoh A, Tsuji S, Okada Y, et al. (2009) Preliminary clinical evaluation of toxicity and efficacy of a new astaxanthinrich Haematococcus pluvialis extract. J Clin Biochem Nutr 44, 280-284.
26. Satoh A, Kawamura T, Horibe T, et al. (2009) Effect of the intake of astaxanthin-containing Haematococcus pluvialis extract on the severity, immunofunction and physiological function in patients with atopic dermatitis. J Environ Dermatol Cutan Allergol 3 429-438 [in Japanese].