Inhibition of Pim1 kinase prevents peanut allergy by enhancing Runx3 expression and suppressing TH2 and TH17 T-cell differentiation

Journal of Allergy and Clinical Immunology

Volumn 130, Issue 4, 2012, Pages

  Wang, Meiqin ^a   Okamoto, Masakazu ^a   Domenico, Joanne ^a   Han, Junyan ^a   Ashino, Shigeru ^a   Shin, Yoo Seob ^a   Gelfand, Erwin W ^a,b  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

^b DEPARTMENT OF MEDICINE   (United States)

Author keywords

Intestinal Allergy; Peanut; Pim1 Kinase; Runx3

Indexed keywords

AR 460770; AR 60770; ENZYME INHIBITOR; PROTEIN KINASE PIM 1; TRANSCRIPTION FACTOR RUNX3; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL CULTURE; CELL EXPANSION; CELL FUNCTION; CONTROLLED STUDY; ENTERITIS; ENZYME INHIBITION; FEMALE; LYMPHOCYTE DIFFERENTIATION; MOUSE; NONHUMAN; PEANUT ALLERGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INTERACTION; SIGNAL TRANSDUCTION; TH17 CELL; TH2 CELL; WILD TYPE;

EID: 84869143393     PISSN: 00916749     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2012.07.032     Document Type: Article

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