Oral peanut immunotherapy in children with peanut anaphylaxis

Journal of Allergy and Clinical Immunology

Volumn 126, Issue 1, 2010, Pages

  Blumchen, Katharina ^a   Ulbricht, Helen ^a   Staden, Ute ^a   Dobberstein, Kerstin ^a   Beschorner, John ^a   de Oliveira, Lucila Camargo Lopes ^a   Shreffler, Wayne G ^b   Sampson, Hugh A ^b   Niggemann, Bodo ^a   Wahn, Ulrich ^a   Beyer, Kirsten ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

Allergy; anaphylaxis; children; food; oral immunotherapy; peanut; specific oral tolerance induction; tolerance

Indexed keywords

IMMUNOGLOBULIN E; IMMUNOGLOBULIN G4; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 5; PLACEBO;

ADOLESCENT; ANAPHYLAXIS; ARTICLE; CHILD; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CYTOKINE PRODUCTION; HUMAN; IMMUNOTHERAPY; LUNG; OBSTRUCTION; PEANUT; PEANUT ALLERGY; PERIPHERAL BLOOD MONONUCLEAR CELL; PRESCHOOL CHILD; PRIORITY JOURNAL; SCHOOL CHILD;

EID: 77953958163     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jaci.2010.04.030     Document Type: Article

References (37)

1. Sicherer S.H., Munoz-Furlong A., and Sampson H.A. Prevalence of peanut and tree nut allergy in the United States determined by means of a random digit dial telephone survey: a 5-year follow-up study. J Allergy Clin Immunol 112 (2003) 1203-1207
2. Ben-Shoshan M., Kagan R.S., Alizadehfar R., Joseph L., Turnbull E., St Pierre Y., et al. Is the prevalence of peanut allergy increasing? a 5-year follow-up study in children in Montreal. J Allergy Clin Immunol 123 (2009) 783-788
3. Du Toit G., Katz Y., Sasieni P., Mesher D., Maleki S.J., Fisher H.R., et al. Early consumption of peanuts in infancy is associated with a low prevalence of peanut allergy. J Allergy Clin Immunol 122 (2008) 984-991
4. Wood R.A. The natural history of food allergy. Pediatrics 111 (2003) 1631-1637
5. Yu J.W., Kagan R., Verreault N., Nicolas N., Joseph L., St Pierre Y., et al. Accidental ingestions in children with peanut allergy. J Allergy Clin Immunol 118 (2006) 466-472
6. Ewan P.W., and Clark A.T. Efficacy of a management plan based on severity assessment in longitudinal and case-controlled studies of 747 children with nut allergy: proposal for good practice. Clin Exp Allergy 35 (2005) 751-756
7. Pumphrey R.S. Lessons for management of anaphylaxis from a study of fatal reactions. Clin Exp Allergy 30 (2000) 1144-1150
8. Mehl A., Wahn U., and Niggemann B. Anaphylactic reactions in children-a questionnaire-based survey in Germany. Allergy 60 (2005) 1440-1445
9. Host A., and Halken S. A prospective study of cow milk allergy in Danish infants during the first 3 years of life: clinical course in relation to clinical and immunological type of hypersensitivity reaction. Allergy 45 (1990) 587-596
10. Skolnick H.S., Conover-Walker M.K., Koerner C.B., Sampson H.A., Burks W., and Wood R.A. The natural history of peanut allergy. J Allergy Clin Immunol 107 (2001) 367-374
11. Pumphrey R.S., and Gowland M.H. Further fatal allergic reactions to food in the United Kingdom, 1999-2006. J Allergy Clin Immunol 119 (2007) 1018-1019
12. Primeau M.N., Kagan R., Joseph L., Lim H., Dufresne C., Duffy C., et al. The psychological burden of peanut allergy as perceived by adults with peanut allergy and the parents of peanut-allergic children. Clin Exp Allergy 30 (2000) 1135-1143
13. Oppenheimer J.J., Nelson H.S., Bock S.A., Christensen F., and Leung D.Y. Treatment of peanut allergy with rush immunotherapy. J Allergy Clin Immunol 90 (1992) 256-262
14. Nelson H.S., Lahr J., Rule R., Bock A., and Leung D. Treatment of anaphylactic sensitivity to peanuts by immunotherapy with injections of aqueous peanut extract. J Allergy Clin Immunol 99 (1997) 744-751
15. Leung D.Y., Sampson H.A., Yunginger J.W., Burks Jr. A.W., Schneider L.C., Wortel C.H., et al. Effect of anti-IgE therapy in patients with peanut allergy. N Engl J Med 348 (2003) 986-993
16. Li X.M., Srivastava K., Grishin A., Huang C.K., Schofield B., Burks W., et al. Persistent protective effect of heat-killed Escherichia coli producing "engineered," recombinant peanut proteins in a murine model of peanut allergy. J Allergy Clin Immunol 112 (2003) 159-167
17. Srivastava K.D., Kattan J.D., Zou Z.M., Li J.H., Zhang L., Wallenstein S., et al. The Chinese herbal medicine formula FAHF-2 completely blocks anaphylactic reactions in a murine model of peanut allergy. J Allergy Clin Immunol 115 (2005) 171-178
18. Souci S., Fachmann W., and Kraut H. Food composition and nutrition tables. 7th ed. (2008), Medpharm Scientific Publishers, Stuttgart
19. Burks A.W., Williams L.W., Connaughton C., Cockrell G., O'Brien T.J., and Helm R.M. Identification and characterization of a second major peanut allergen, Ara h II, with use of the sera of patients with atopic dermatitis and positive peanut challenge. J Allergy Clin Immunol 90 (1992) 962-969
20. Staden U., Blumchen K., Blankenstein N., Dannenberg N., Ulbricht H., Dobberstein K., et al. Rush oral immunotherapy in children with persistent cow's milk allergy. J Allergy Clin Immunol 122 (2008) 418-419
21. Vadas P., and Perelman B. Presence of undeclared peanut protein in chocolate bars imported from Europe. J Food Prot 66 (2003) 1932-1934
22. Schappi G.F., Konrad V., Imhof D., Etter R., and Wuthrich B. Hidden peanut allergens detected in various foods: findings and legal measures. Allergy 56 (2001) 1216-1220
23. Patriarca G., Nucera E., Pollastrini E., Roncallo C., De Pasquale T., Lombardo C., et al. Oral specific desensitization in food-allergic children. Dig Dis Sci 52 (2007) 1662-1672
24. Clark A.T., Islam S., King Y., Deighton J., Anagnostou K., and Ewan P.W. Successful oral tolerance induction in severe peanut allergy. Allergy 64 (2009) 1218-1220
25. Mansfield L. Successful oral desensitization for systemic peanut allergy. Ann Allergy Asthma Immunol 97 (2006) 266-267
26. Jones S.M., Pons L., Roberts J.L., Scurlock A.M., Perry T.T., Kulis M., et al. Clinical efficacy and immune regulation with peanut oral immunotherapy. J Allergy Clin Immunol 124 (2009) 292-300 e1-97
27. Skripak J.M., Nash S.D., Rowley H., Brereton N.H., Oh S., Hamilton R.G., et al. A randomized, double-blind, placebo-controlled study of milk oral immunotherapy for cow's milk allergy. J Allergy Clin Immunol 122 (2008) 1154-1160
28. Longo G., Barbi E., Berti I., Meneghetti R., Pittalis A., Ronfani L., et al. Specific oral tolerance induction in children with very severe cow's milk-induced reactions. J Allergy Clin Immunol 121 (2008) 343-347
29. Hofmann A.M., Scurlock A.M., Jones S.M., Palmer K.P., Lokhnygina Y., Steele P.H., et al. Safety of a peanut oral immunotherapy protocol in children with peanut allergy. J Allergy Clin Immunol 124 (2009) 286-291 91 e1-6
30. Sampson H.A., Munoz-Furlong A., Campbell R.L., Adkinson Jr. N.F., Bock S.A., Branum A., et al. Second symposium on the definition and management of anaphylaxis: summary report-Second National Institute of Allergy and Infectious Disease/Food Allergy and Anaphylaxis Network symposium. J Allergy Clin Immunol 117 (2006) 391-397
31. Muraro A., Roberts G., Clark A., Eigenmann P.A., Halken S., Lack G., et al. The management of anaphylaxis in childhood: position paper of the European Academy of Allergology and Clinical Immunology. Allergy 62 (2007) 857-871
32. Turcanu V., Maleki S.J., and Lack G. Characterization of lymphocyte responses to peanuts in normal children, peanut-allergic children, and allergic children who acquired tolerance to peanuts. J Clin Invest 111 (2003) 1065-1072
33. Weiner H.L. Oral tolerance, an active immunologic process mediated by multiple mechanisms. J Clin Invest 106 (2000) 935-937
34. Hoyne G.F., Tan K., Corsin-Jimenez M., Wahl K., Stewart M., Howie S.E., et al. Immunological tolerance to inhaled antigen. Am J Respir Crit Care Med 162 (2000) S169-S174
35. Karlsson M.R., Rugtveit J., and Brandtzaeg P. Allergen-responsive CD4+CD25+ regulatory T cells in children who have outgrown cow's milk allergy. J Exp Med 199 (2004) 1679-1688
36. Wahn U., Tabar A., Kuna P., Halken S., Montagut A., de Beaumont O., et al. Efficacy and safety of 5-grass-pollen sublingual immunotherapy tablets in pediatric allergic rhinoconjunctivitis. J Allergy Clin Immunol 123 (2009) 160-166 e3
37. Bufe A., Eberle P., Franke-Beckmann E., Funck J., Kimmig M., Klimek L., et al. Safety and efficacy in children of an SQ-standardized grass allergen tablet for sublingual immunotherapy. J Allergy Clin Immunol 123 (2009) 167-173 e7