ANIMAL EXPERIMENT;
ANIMAL MODEL;
ANTICONVULSANT ACTIVITY;
ARTICLE;
CENTRAL NERVOUS SYSTEM;
DRUG DOSE INCREASE;
DRUG STRUCTURE;
DRUG SYNTHESIS;
ELECTRIC SHOCK;
MALE;
MOUSE;
NONHUMAN;
PROTON NUCLEAR MAGNETIC RESONANCE;
SEIZURE;
Substituted 1,2-dihydrophthalazines: Potent, selective, and noncompetitive inhibitors of the AMPA receptor
Pelletier C. J., Hesson P. D., Jones A. K. et al. Substituted 1,2-dihydrophthalazines: Potent, selective, and noncompetitive inhibitors of the AMPA receptor. J Med Chem: 1996; 39 343 346
Synthesis and anticonvulsant activity of novel and potent 6,7-methylenedioxyphthalazin-1(2H)-ones
Grasso S., Sarro D. G., Sarro D. A. et al. Synthesis and anticonvulsant activity of novel and potent 6,7-methylenedioxyphthalazin-1(2H)-ones. J Med Chem: 2000; 43 2851 2859
Inhibition of tobacco bacterial wilt with sulfone derivatives containing an 1,3,4-oxadiazole Moiety
Xu W., Han F., He M. et al. Inhibition of tobacco bacterial wilt with sulfone derivatives containing an 1,3,4-oxadiazole Moiety. J Agric Food Chem: 2012; 60 1036 1041
Microwave assisted synthesis, characterization & biological evaluation of Benzimidazole substituted1,3,4-oxadiazole
Jhal K. K., Kumar Y., Shaharyar M. et al. Microwave assisted synthesis, characterization & biological evaluation of Benzimidazole substituted1,3,4-oxadiazole. Int J ChemTech Res: 2010; 2 716 727
Synthesis and evaluation of substituted diphenyl-1,3,4-oxadiazole derivatives for central nervous system depressant activity
Singh P., Sharma K. P., Sharma K. J. et al. Synthesis and evaluation of substituted diphenyl-1,3,4-oxadiazole derivatives for central nervous system depressant activity. Org Med Chem Lett: 2012; 2 08 1 10
Quantitative chemical structure-pharmacokinetic data relationships. IV. Relationships between pharmacokinetic data and lipophilicity of iodine-substituted aromatic and arylaliphatic compounds
Laznicek M., Beno P., Waisser K. et al. Quantitative chemical structure-pharmacokinetic data relationships. IV. Relationships between pharmacokinetic data and lipophilicity of iodine-substituted aromatic and arylaliphatic compounds. Cesko-Slovenska Farmacie: 1985; 34 09 353 358
Effects of lipophilicity on the affinity and nonspecific binding of iodinated benzothiazole derivatives
Yanming W., Chester A. M., Guo-Feng H. et al. Effects of lipophilicity on the affinity and nonspecific binding of iodinated benzothiazole derivatives. J mol neurosci: 2003; 20 03 255 260
Pharmacological evaluation of some new 1-substituted-4 hydroxyphthalazines
Sivakumar R., Gnanasam K. S., Ramachandran S. et al. Pharmacological evaluation of some new 1-substituted-4 hydroxyphthalazines. Eur J med Chem: 2002; 37 793 801
Systemically Active Antagonists of the Glycine Site of the N-Methyl-D-aspartate Receptor: Electrophysiological, Biochemical and Behavioral Characterization
Parsons G. C., Danysz W., Quack N. G. et al. Systemically Active Antagonists of the Glycine Site of the N-Methyl-D-aspartate Receptor: Electrophysiological, Biochemical and Behavioral Characterization. J Pharmacol Exp Ther: 1997; 283 1264 1275
P-Substituted N-acetyl-L-(S)- and D(R)-.alpha.-amino-N phenylsuccinimides and -glutarimides. Substituent effects on stereoselective anticonvulsant activity
Witak T. D., Seth K. S., Baizman R. E. et al. p-Substituted N-acetyl-L-(S)- and D(R)-.alpha.-amino-N phenylsuccinimides and -glutarimides. Substituent effects on stereoselective anticonvulsant activity. J Med Chem: 1972; 15 1117 1123