Substituted 1,2-dihydrophthalazines: Potent, selective, and noncompetitive inhibitors of the AMPA receptor

Journal of Medicinal Chemistry

Volumn 39, Issue 2, 1996, Pages 343-346

  Pelletier, Jeffrey C ^a   Hesson, David P ^a   Jones, Kenneth A ^a   Costa, Anna Maria ^a  

^a Symphony Pharmaceuticals   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 (4 AMINOPHENYL) 3,4 DIHYDRO 4 METHYL 3 METHYLCARBAMOYL 7,8 METHYLENEDIOXY 5H 2,3 BENZODIAZEPINE; 1 (4 AMINOPHENYL) 4 METHYL 7,8 METHYLENEDIOXY 5H 2,3 BENZODIAZEPINE; 4 (4 AMINOPHENYL) N BUTYL 1,2 DIHYDRO 1 METHYL 6,7 METHYLENEDIOXY 2 PHTHALAZINECARBOXAMIDE; 6 NITRO 7 SULFAMOYLBENZO[F]QUINOXALINE 2,3 DIONE; ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLEPROPIONIC ACID; AMPA RECEPTOR; GLUTAMATE RECEPTOR; GLUTAMATE RECEPTOR AGONIST; GLUTAMATE RECEPTOR ANTAGONIST; PHTHALAZINE DERIVATIVE; RECEPTOR SUBTYPE; SYM 2207; UNCLASSIFIED DRUG;

ARTICLE; DRUG PENETRATION; NERVE CELL LESION; NERVE DEGENERATION; NEUROPROTECTION; RECEPTOR BINDING; STRUCTURE ACTIVITY RELATION;

ANIMALS; CELLS, CULTURED; HUMANS; KIDNEY CORTEX; PHTHALAZINES; RATS; RECEPTORS, AMPA;

EID: 0030034762     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm950740w     Document Type: Article

References (20)