Crystal structures of branched-chain amino acid aminotransferase complexed with glutamate and glutarate: True reaction intermediate and double substrate recognition of the enzyme

Biochemistry

Volumn 42, Issue 13, 2003, Pages 3725-3733

  Goto, Masaru ^a   Miyahara, Ikuko ^a   Hayashi, Hideyuki ^b   Kagamiyama, Hiroyuki ^b   Hirotsu, Ken ^a  

^a Osaka Prefecture University   (Japan)

^b OSAKA MEDICAL COLLEGE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ABSORPTION; AMINO ACIDS; CRYSTAL STRUCTURE; ENZYMES; SUBSTRATES;

BOND STRUCTURE;

BIOCHEMISTRY;

2 OXOGLUTARIC ACID; AROMATIC AMINO ACID; BACTERIAL ENZYME; BRANCHED CHAIN AMINO ACID AMINOTRANSFERASE; CARBOXYLIC ACID; GLUTAMIC ACID; GLUTARIC ACID; HISTIDINOL PHOSPHATASE; IMINE; ISOLEUCINE; KITIMINE; LEUCINE; POLYPEPTIDE; UNCLASSIFIED DRUG; VALINE;

ABSORPTION SPECTROSCOPY; AMINO ACID TRANSPORT; ARTICLE; BIOSYNTHESIS; CATALYSIS; CHEMICAL BOND; CHEMICAL REACTION; COMPLEX FORMATION; CRYSTAL STRUCTURE; ENZYME ANALYSIS; ENZYME BINDING; ENZYME STRUCTURE; ENZYME SUBSTRATE COMPLEX; ESCHERICHIA COLI; HYDROGEN BOND; HYDROPHOBICITY; PRIORITY JOURNAL; PROTEIN DOMAIN; SIGNAL TRANSDUCTION; X RAY DIFFRACTION;

BINDING SITES; ESCHERICHIA COLI; GLUTAMATES; GLUTARATES; HYDROGEN BONDING; MODELS, MOLECULAR; PROTEIN CONFORMATION; PYRIDOXAL PHOSPHATE; STEREOISOMERISM; SUBSTRATE SPECIFICITY; TRANSAMINASES; X-RAY DIFFRACTION;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; HOMO; NEGIBACTERIA;

EID: 0037426327     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi026722f     Document Type: Article

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