Structural analysis of mycobacterial branched-chain aminotransferase: Implications for inhibitor design

Acta Crystallographica Section D: Biological Crystallography

Volumn 66, Issue 5, 2010, Pages 549-557

  Castell, Alina ^a   Mille, Christian ^a   Unge, Torsten ^a  

^a UPPSALA UNIVERSITY   (Sweden)

Author keywords

Branched chain aminotransferases; Mycobacterium smegmatis; Mycobacterium tuberculosis; O benzylhydroxylamine; Rv2210c

Indexed keywords

AMINOTRANSFERASE; BRANCHED CHAIN AMINO ACID TRANSAMINASE; BRANCHED-CHAIN-AMINO-ACID TRANSAMINASE; ENZYME INHIBITOR;

AMINO ACID SEQUENCE; ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; DRUG ANTAGONISM; ENZYME ACTIVE SITE; ENZYMOLOGY; METABOLISM; MOLECULAR GENETICS; MYCOBACTERIUM; MYCOBACTERIUM TUBERCULOSIS; PROTEIN CONFORMATION; SEQUENCE ALIGNMENT; X RAY CRYSTALLOGRAPHY;

AMINO ACID SEQUENCE; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; ENZYME INHIBITORS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MYCOBACTERIUM; MYCOBACTERIUM TUBERCULOSIS; PROTEIN CONFORMATION; SEQUENCE ALIGNMENT; TRANSAMINASES;

BACTERIA (MICROORGANISMS); MYCOBACTERIUM SMEGMATIS; MYCOBACTERIUM TUBERCULOSIS;

EID: 77952058501     PISSN: 09074449     EISSN: 13990047     Source Type: Journal    
DOI: 10.1107/S0907444910004877     Document Type: Article

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