메뉴 건너뛰기




Volumn 38, Issue 2, 2012, Pages 457-462

Advances and prospects of anginex as a promising anti-angiogenesis and anti-tumor agent

Author keywords

Sheet; peptides; Anginex; Angiogenesis; Endothelial cell; Tumor growth

Indexed keywords

ANGINEX; ANGIOSTATIN; CARBOPLATIN; ENDOSTATIN; FIBRONECTIN; GALECTIN 1; INTERLEUKIN 8; THROMBOCYTE FACTOR 4;

EID: 84869101647     PISSN: 01969781     EISSN: 18735169     Source Type: Journal    
DOI: 10.1016/j.peptides.2012.09.007     Document Type: Review
Times cited : (24)

References (53)
  • 1
    • 13844315323 scopus 로고    scopus 로고
    • Angiostatic peptides use plasma fibronectin to home to angiogenic vasculature
    • M.E. Akerman, J. Pilch, D. Peters, and E. Ruoslahti Angiostatic peptides use plasma fibronectin to home to angiogenic vasculature Proc Natl Acad Sci USA 102 2005 2040 2045
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 2040-2045
    • Akerman, M.E.1    Pilch, J.2    Peters, D.3    Ruoslahti, E.4
  • 2
    • 33947512932 scopus 로고    scopus 로고
    • Antiangiogenesis therapy using a novel angiogenesis inhibitor, anginex, following radiation causes tumor growth delay
    • M. Amano, M. Suzuki, S. Andoh, H. Monzen, K. Terai, and B. Williams Antiangiogenesis therapy using a novel angiogenesis inhibitor, anginex, following radiation causes tumor growth delay Int J Clin Oncol 12 2007 42 47
    • (2007) Int J Clin Oncol , vol.12 , pp. 42-47
    • Amano, M.1    Suzuki, M.2    Andoh, S.3    Monzen, H.4    Terai, K.5    Williams, B.6
  • 3
    • 0037967272 scopus 로고    scopus 로고
    • Tumorigenesis and the angiogenic switch
    • G. Bergers, and L.E. Benjamin Tumorigenesis and the angiogenic switch Nat Rev Cancer 3 2003 401 410
    • (2003) Nat Rev Cancer , vol.3 , pp. 401-410
    • Bergers, G.1    Benjamin, L.E.2
  • 4
    • 0035958848 scopus 로고    scopus 로고
    • A novel linear amphipathic beta-sheet cationic antimicrobial peptide with enhanced selectivity for bacterial lipids
    • J. Blazyk, R. Wiegand, J. Klein, J. Hammer, R.M. Epand, and R.F. Epand A novel linear amphipathic beta-sheet cationic antimicrobial peptide with enhanced selectivity for bacterial lipids J Biol Chem 276 2001 27899 27906
    • (2001) J Biol Chem , vol.276 , pp. 27899-27906
    • Blazyk, J.1    Wiegand, R.2    Klein, J.3    Hammer, J.4    Epand, R.M.5    Epand, R.F.6
  • 7
    • 0027122245 scopus 로고
    • Crystal structure of transforming growth factor-beta 2: An unusual fold for the superfamily
    • S. Daopin, K.A. Piez, Y. Ogawa, and D.R. Davies Crystal structure of transforming growth factor-beta 2: an unusual fold for the superfamily Science 257 1992 369 373
    • (1992) Science , vol.257 , pp. 369-373
    • Daopin, S.1    Piez, K.A.2    Ogawa, Y.3    Davies, D.R.4
  • 9
    • 34250660932 scopus 로고    scopus 로고
    • Scheduling of radiation with angiogenesis inhibitors anginex and avastin improves therapeutic outcome viavessel normalization
    • R.P. Dings, M. Loren, H. Heun, E. McNiel, A.W. Griffioen, and K.H. Mayo Scheduling of radiation with angiogenesis inhibitors anginex and avastin improves therapeutic outcome viavessel normalization Clin Cancer Res 13 2007 3395 3402
    • (2007) Clin Cancer Res , vol.13 , pp. 3395-3402
    • Dings, R.P.1    Loren, M.2    Heun, H.3    McNiel, E.4    Griffioen, A.W.5    Mayo, K.H.6
  • 11
    • 74949118349 scopus 로고    scopus 로고
    • Inhibiting tumor growth by targeting tumor vasculature with galectin-1 antagonist anginex conjugated to the cytotoxic acylfulvene, 6- hydroxylpropylacylfulvene
    • R.P. Dings, E.S. Van Laar, M. Loren, J. Webber, Y. Zhang, and S.J. Waters Inhibiting tumor growth by targeting tumor vasculature with galectin-1 antagonist anginex conjugated to the cytotoxic acylfulvene, 6- hydroxylpropylacylfulvene Bioconjugate Chem 21 2010 20 27
    • (2010) Bioconjugate Chem , vol.21 , pp. 20-27
    • Dings, R.P.1    Van Laar, E.S.2    Loren, M.3    Webber, J.4    Zhang, Y.5    Waters, S.J.6
  • 12
    • 17844374383 scopus 로고    scopus 로고
    • Anginex synergizes with radiation therapy to inhibit tumor growth by radiosensitizing endothelial cells
    • R.P. Dings, B.W. Williams, C.W. Song, A.W. Griffioen, K.H. Mayo, and R.J. Griffin Anginex synergizes with radiation therapy to inhibit tumor growth by radiosensitizing endothelial cells Int J Cancer 115 2005 312 319
    • (2005) Int J Cancer , vol.115 , pp. 312-319
    • Dings, R.P.1    Williams, B.W.2    Song, C.W.3    Griffioen, A.W.4    Mayo, K.H.5    Griffin, R.J.6
  • 13
    • 0037439824 scopus 로고    scopus 로고
    • The designed angiostatic peptide anginex synergistically improves chemotherapy and antiangiogenesis therapy with angiostatin1
    • R.P. Dings, Y. Yokoyama, S. Ramakrishnan, A.W. Griffioen, and K.H. Mayo The designed angiostatic peptide anginex synergistically improves chemotherapy and antiangiogenesis therapy with angiostatin1 Cancer Res 63 2003 382 385
    • (2003) Cancer Res , vol.63 , pp. 382-385
    • Dings, R.P.1    Yokoyama, Y.2    Ramakrishnan, S.3    Griffioen, A.W.4    Mayo, K.H.5
  • 14
    • 70349946971 scopus 로고    scopus 로고
    • Anti-angiogenesis and anti-tumor activity of AdNT4-anginex: A recombinant adenovirus secreting and expressing anginex
    • D.F. Dong, E.X. Li, J.B. Wang, Y.Y. Wu, F. Shi, and J.J. Guo Anti-angiogenesis and anti-tumor activity of AdNT4-anginex: a recombinant adenovirus secreting and expressing anginex Cancer Lett 28 2009 218 224
    • (2009) Cancer Lett , vol.28 , pp. 218-224
    • Dong, D.F.1    Li, E.X.2    Wang, J.B.3    Wu, Y.Y.4    Shi, F.5    Guo, J.J.6
  • 15
    • 0026787018 scopus 로고
    • The structure of human lymphotoxin (tumor necrosis factor-beta) at 1.9 A/resolution
    • M.J. Eck, M. Ultsch, E. Rinderknecht, A.M. de Vos, and S.R. Sprang The structure of human lymphotoxin (tumor necrosis factor-beta) at 1.9 A/resolution J Biol Chem 267 1992 2119 2122
    • (1992) J Biol Chem , vol.267 , pp. 2119-2122
    • Eck, M.J.1    Ultsch, M.2    Rinderknecht, E.3    De Vos, A.M.4    Sprang, S.R.5
  • 16
    • 0028929803 scopus 로고
    • Angiogenesis in cancer, vascular, rheumatoid and other disease
    • J. Folkman Angiogenesis in cancer, vascular, rheumatoid and other disease Nat Med 1 1995 27 31
    • (1995) Nat Med , vol.1 , pp. 27-31
    • Folkman, J.1
  • 17
    • 0023157363 scopus 로고
    • Angiogenic factors
    • J. Folkman, and M. Klagsbrun Angiogenic factors Science 235 1987 442 447
    • (1987) Science , vol.235 , pp. 442-447
    • Folkman, J.1    Klagsbrun, M.2
  • 18
    • 17444376781 scopus 로고    scopus 로고
    • Potentiation of the antitumor effect of ionizing radiation by brief concomitant exposures to angiostatin
    • D.H. Gorski, H.J. Mauceri, R.M. Salloum, S. Gately, S. Hellman, and M.A. Beckett Potentiation of the antitumor effect of ionizing radiation by brief concomitant exposures to angiostatin Cancer Res 58 1998 5686 5689
    • (1998) Cancer Res , vol.58 , pp. 5686-5689
    • Gorski, D.H.1    Mauceri, H.J.2    Salloum, R.M.3    Gately, S.4    Hellman, S.5    Beckett, M.A.6
  • 19
    • 0029739950 scopus 로고    scopus 로고
    • Control of adhesion-dependent cell survival by focal adhesion kinase
    • S.M. Frisch, K. Vuori, E. Ruoslahti, and P.Y. Chan-Hui Control of adhesion-dependent cell survival by focal adhesion kinase J Cell Biol 134 1996 793 799
    • (1996) J Cell Biol , vol.134 , pp. 793-799
    • Frisch, S.M.1    Vuori, K.2    Ruoslahti, E.3    Chan-Hui, P.Y.4
  • 20
    • 0029044454 scopus 로고
    • B/PI-derived synthetic peptides: Synergistic effects in tethered bactericidal and endotoxin neutralizing peptides
    • B.H. Gray, J.R. Haseman, and K.H. Mayo B/PI-derived synthetic peptides: synergistic effects in tethered bactericidal and endotoxin neutralizing peptides Biochim Biophys Acta 1244 1995 185 190
    • (1995) Biochim Biophys Acta , vol.1244 , pp. 185-190
    • Gray, B.H.1    Haseman, J.R.2    Mayo, K.H.3
  • 21
    • 0034090097 scopus 로고    scopus 로고
    • Angiogenesis: Potentials for pharmacologic intervention in the treatment of cancer, cardiovascular diseases, and chronic inflammation
    • A.W. Griffioen, and G. Molema Angiogenesis: potentials for pharmacologic intervention in the treatment of cancer, cardiovascular diseases, and chronic inflammation Pharmacol Rev 52 2000 237 268
    • (2000) Pharmacol Rev , vol.52 , pp. 237-268
    • Griffioen, A.W.1    Molema, G.2
  • 23
    • 0027944881 scopus 로고
    • Inhibition of endothelial cell proliferation by platelet factor-4 involves a unique action on S phase progression
    • S.K. Gupta, and J.P. Singh Inhibition of endothelial cell proliferation by platelet factor-4 involves a unique action on S phase progression J Cell Biol 127 1994 1121 1127
    • (1994) J Cell Biol , vol.127 , pp. 1121-1127
    • Gupta, S.K.1    Singh, J.P.2
  • 24
    • 0030576517 scopus 로고    scopus 로고
    • Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis
    • D. Hanahan, and J. Folkman Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis Cell 86 1996 353 364
    • (1996) Cell , vol.86 , pp. 353-364
    • Hanahan, D.1    Folkman, J.2
  • 25
    • 0030941296 scopus 로고    scopus 로고
    • NMR structure of a de novo designed, peptide 33mer with two distinct, compact β-sheet folds
    • E. Ilyina, V. Roongta, and K.H. Mayo NMR structure of a de novo designed, peptide 33mer with two distinct, compact β-sheet folds Biochem J 36 1997 5245 5250
    • (1997) Biochem J , vol.36 , pp. 5245-5250
    • Ilyina, E.1    Roongta, V.2    Mayo, K.H.3
  • 26
    • 0024539057 scopus 로고
    • Structure of tumour necrosis factor
    • E.Y. Jones, E.D. Stuart, and N.P. Walker Structure of tumour necrosis factor Nature 338 1989 225 228
    • (1989) Nature , vol.338 , pp. 225-228
    • Jones, E.Y.1    Stuart, E.D.2    Walker, N.P.3
  • 27
    • 0029060187 scopus 로고
    • The IP-10 chemokine binds to a specific cell surface heparan sulfate site shared with platelet factor 4 and inhibits endothelial cell proliferation
    • A.D. Luster, S.M. Greenberg, and P. Leder The IP-10 chemokine binds to a specific cell surface heparan sulfate site shared with platelet factor 4 and inhibits endothelial cell proliferation J Exp Med 182 1995 219 223
    • (1995) J Exp Med , vol.182 , pp. 219-223
    • Luster, A.D.1    Greenberg, S.M.2    Leder, P.3
  • 29
    • 0242580732 scopus 로고    scopus 로고
    • Design of a partial peptide mimetic of anginex with antiangiogenic and anticancer activity
    • 14
    • K.H. Mayo, R.P. Dings, C. Flader, I. Nesmelova, B. Hargittai, and D.W. van der Schaft Design of a partial peptide mimetic of anginex with antiangiogenic and anticancer activity J Biol Chem 278 46 2003 45746 45752 14
    • (2003) J Biol Chem , vol.278 , Issue.46 , pp. 45746-45752
    • Mayo, K.H.1    Dings, R.P.2    Flader, C.3    Nesmelova, I.4    Hargittai, B.5    Van Der Schaft, D.W.6
  • 30
    • 0032538127 scopus 로고    scopus 로고
    • β-Sheet-forming peptide 33mers with potent human bacterial/permeability increasing protein-like bacterial and endotoxin neutralizing activities
    • K.H. Mayo, J. Haseman, E. Ilyina, and Gray B. Designed β-Sheet-forming peptide 33mers with potent human bacterial/permeability increasing protein-like bacterial and endotoxin neutralizing activities Biochim Biophys Acta 1425 1998 81 92
    • (1998) Biochim Biophys Acta , vol.1425 , pp. 81-92
    • Mayo, K.H.1    Haseman, J.2    Ilyina, E.3    Designed, G.B.4
  • 31
    • 0029927321 scopus 로고    scopus 로고
    • A recipe for designing water-soluble, beta-sheet-forming peptides
    • K.H. Mayo, E. Ilyina, and H. Park A recipe for designing water-soluble, beta-sheet-forming peptides Protein Sci 5 1996 1301 1315
    • (1996) Protein Sci , vol.5 , pp. 1301-1315
    • Mayo, K.H.1    Ilyina, E.2    Park, H.3
  • 32
    • 0035675008 scopus 로고    scopus 로고
    • Designed beta-sheet peptides that inhibit proliferation and induce apoptosis in endothelial cells
    • K.H. Mayo, D.W. van der Schaft, and A.W. Griffioen Designed beta-sheet peptides that inhibit proliferation and induce apoptosis in endothelial cells Angiogenesis 4 2001 45 51
    • (2001) Angiogenesis , vol.4 , pp. 45-51
    • Mayo, K.H.1    Van Der Schaft, D.W.2    Griffioen, A.W.3
  • 33
    • 0342981754 scopus 로고    scopus 로고
    • Implications for the assay and biological activity of interleukin-8: Results of a WHO international collaborative study
    • A.R. Mire-Sluis, D.R. Gaines, and R. Thorpe Implications for the assay and biological activity of interleukin-8: results of a WHO international collaborative study J Immunol Methods 200 1997 1 16
    • (1997) J Immunol Methods , vol.200 , pp. 1-16
    • Mire-Sluis, A.R.1    Gaines, D.R.2    Thorpe, R.3
  • 34
    • 0032171619 scopus 로고    scopus 로고
    • Rocking the foundations of solid tumor growth by attacking the tumor's blood supply
    • G. Molema, and A.W. Griffioen Rocking the foundations of solid tumor growth by attacking the tumor's blood supply Immunol Today 19 1998 392 394
    • (1998) Immunol Today , vol.19 , pp. 392-394
    • Molema, G.1    Griffioen, A.W.2
  • 35
    • 0031454617 scopus 로고    scopus 로고
    • Endostatin: An endogenous inhibitor of angiogenesis and tumor growth
    • M.S. O'Reilly, T. Boehm, Y. Shing, N. Fukai, G. Vasios, and W.S. Lane Endostatin: an endogenous inhibitor of angiogenesis and tumor growth Cell 88 1997 277 285
    • (1997) Cell , vol.88 , pp. 277-285
    • O'Reilly, M.S.1    Boehm, T.2    Shing, Y.3    Fukai, N.4    Vasios, G.5    Lane, W.S.6
  • 36
    • 0027970092 scopus 로고
    • Angiostatin: A novel angiogenesis inhibitor that mediates the suppression of metastases by a Lewis lung carcinoma
    • M.S. O'Reilly, L. Holmgren, Y. Shing, C. Chen, R.A. Rosenthal, and M. Moses Angiostatin: a novel angiogenesis inhibitor that mediates the suppression of metastases by a Lewis lung carcinoma Cell 79 1994 315 328
    • (1994) Cell , vol.79 , pp. 315-328
    • O'Reilly, M.S.1    Holmgren, L.2    Shing, Y.3    Chen, C.4    Rosenthal, R.A.5    Moses, M.6
  • 37
    • 18544366816 scopus 로고    scopus 로고
    • Host defense peptides as new weapons in cancer treatment
    • N. Papo, and Y. Shai Host defense peptides as new weapons in cancer treatment Cell Mol Life Sci 62 2005 784 790
    • (2005) Cell Mol Life Sci , vol.62 , pp. 784-790
    • Papo, N.1    Shai, Y.2
  • 40
    • 0032445492 scopus 로고    scopus 로고
    • Vasostatin, a calreticulin fragment, inhibits angiogenesis and supresses tumor growth
    • S.E. Pike, L. Yao, K.D. Jones, B. Cherney, E. Appella, and K. Sakaguchi Vasostatin, a calreticulin fragment, inhibits angiogenesis and supresses tumor growth J Exp Med 188 1998 2349 2356
    • (1998) J Exp Med , vol.188 , pp. 2349-2356
    • Pike, S.E.1    Yao, L.2    Jones, K.D.3    Cherney, B.4    Appella, E.5    Sakaguchi, K.6
  • 41
    • 0024804106 scopus 로고
    • Crystallographic refinement of interleukin-1-beta at 2.0 A/resolution
    • J.P. Priestle, H.P. Schar, and M.G. Grutter Crystallographic refinement of interleukin-1-beta at 2.0 A/resolution Proc Natl Acad Sci USA 86 1989 9667 9671
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 9667-9671
    • Priestle, J.P.1    Schar, H.P.2    Grutter, M.G.3
  • 42
    • 0026093190 scopus 로고
    • Tumor necrosis factor induces apoptosis in normal endothelial cells in vitro
    • B. Robaye, R. Mosselmans, W. Fiers, J.E. Dumont, and P. Galand Tumor necrosis factor induces apoptosis in normal endothelial cells in vitro Am J Pathol 138 1991 447 453
    • (1991) Am J Pathol , vol.138 , pp. 447-453
    • Robaye, B.1    Mosselmans, R.2    Fiers, W.3    Dumont, J.E.4    Galand, P.5
  • 43
    • 0024503338 scopus 로고
    • Regulation of the activity of a new inhibitor of angiogenesis by a cancer suppressor gene
    • F. Rastinejad, P.J. Polverini, and N.P. Bouck Regulation of the activity of a new inhibitor of angiogenesis by a cancer suppressor gene Cell 56 1989 345 355
    • (1989) Cell , vol.56 , pp. 345-355
    • Rastinejad, F.1    Polverini, P.J.2    Bouck, N.P.3
  • 44
    • 0028072225 scopus 로고
    • Inhibition of anchorage-dependent cell spreading triggers apoptosis in cultured human endothelial cells
    • F. Re, A. Zanetti, M. Sironi, N. Polentarutti, L. Lanfrancone, and E. Dejana Inhibition of anchorage-dependent cell spreading triggers apoptosis in cultured human endothelial cells J Cell Biol 127 1994 537 546
    • (1994) J Cell Biol , vol.127 , pp. 537-546
    • Re, F.1    Zanetti, A.2    Sironi, M.3    Polentarutti, N.4    Lanfrancone, L.5    Dejana, E.6
  • 45
    • 0034824597 scopus 로고    scopus 로고
    • From "carpet" mechanism to de-novo designed diastereomeric cell-selective antimicrobial peptides
    • Y. Shai, and Z. Oren From "carpet" mechanism to de-novo designed diastereomeric cell-selective antimicrobial peptides Peptides 22 2001 1629 1641
    • (2001) Peptides , vol.22 , pp. 1629-1641
    • Shai, Y.1    Oren, Z.2
  • 46
    • 0030447720 scopus 로고    scopus 로고
    • Structure of staphylococcal alpha-hemolysin, a heptameric transmembrane pore
    • L. Song, M.R. Hobaugh, C. Shustak, S. Cheley, H. Bayley, and J.E. Gouaux Structure of staphylococcal alpha-hemolysin, a heptameric transmembrane pore Science 274 1996 1859 1866
    • (1996) Science , vol.274 , pp. 1859-1866
    • Song, L.1    Hobaugh, M.R.2    Shustak, C.3    Cheley, S.4    Bayley, H.5    Gouaux, J.E.6
  • 47
    • 70349509441 scopus 로고    scopus 로고
    • NF-kappaB activation in endothelial cells is critical for the activity of angiostatic agents
    • S.P. Tabruyn, S. Memet, P. Ave, C. Verhaeghe, K.H. Mayo, and I. Struman NF-kappaB activation in endothelial cells is critical for the activity of angiostatic agents Mol Cancer Ther 8 2009 2645 2654
    • (2009) Mol Cancer Ther , vol.8 , pp. 2645-2654
    • Tabruyn, S.P.1    Memet, S.2    Ave, P.3    Verhaeghe, C.4    Mayo, K.H.5    Struman, I.6
  • 48
    • 0026486664 scopus 로고
    • Antiangiogenic agents potentiate cytotoxic cancer therapies against primary and metastatic disease
    • B.A. Teicher, E.A. Sotomayor, and Z.D. Huang Antiangiogenic agents potentiate cytotoxic cancer therapies against primary and metastatic disease Cancer Res 52 1992 6702 6704
    • (1992) Cancer Res , vol.52 , pp. 6702-6704
    • Teicher, B.A.1    Sotomayor, E.A.2    Huang, Z.D.3
  • 50
    • 0036884619 scopus 로고    scopus 로고
    • The designer anti-angiogenic peptide anginex targets tumor endothelial cells and inhibits tumor growth in animal models
    • D.W. van der Schaft, R.P. Dings, Q.G. de Lussanet, L.I. van Eijk, A.W. Nap, and R.G. Beets-Tan The designer anti-angiogenic peptide anginex targets tumor endothelial cells and inhibits tumor growth in animal models FASEB J 16 2002 1991 1993
    • (2002) FASEB J , vol.16 , pp. 1991-1993
    • Van Der Schaft, D.W.1    Dings, R.P.2    De Lussanet, Q.G.3    Van Eijk, L.I.4    Nap, A.W.5    Beets-Tan, R.G.6
  • 51
    • 0034234652 scopus 로고    scopus 로고
    • Bactericidal/permeability-increasing protein (BPI) inhibits angiogenesis via induction of apoptosis in vascular endothelial cells
    • D.W. van der Schaft, E.A. Toebes, J.R. Haseman, K.H. Mayo, and A.W. Griffioen Bactericidal/permeability-increasing protein (BPI) inhibits angiogenesis via induction of apoptosis in vascular endothelial cells Blood 96 2000 176 181
    • (2000) Blood , vol.96 , pp. 176-181
    • Van Der Schaft, D.W.1    Toebes, E.A.2    Haseman, J.R.3    Mayo, K.H.4    Griffioen, A.W.5
  • 52
    • 0035757052 scopus 로고    scopus 로고
    • Combined delivery of an antiangiogenic protein (angiostatin) and an immunomodulatory gene (interleukin-12) in the treatment of murine cancer
    • U. Wilczynska, A. Kucharska, J. Szary, and S. Szala Combined delivery of an antiangiogenic protein (angiostatin) and an immunomodulatory gene (interleukin-12) in the treatment of murine cancer Acta Biochim Pol 48 2001 1077 1084
    • (2001) Acta Biochim Pol , vol.48 , pp. 1077-1084
    • Wilczynska, U.1    Kucharska, A.2    Szary, J.3    Szala, S.4
  • 53
    • 0141482075 scopus 로고    scopus 로고
    • Antiangiogenic proteins require plasma fibronectin or vitronectin for in vivo activity
    • M. Yi, T. Sakai, R. Fassler, and E. Ruoslahti Antiangiogenic proteins require plasma fibronectin or vitronectin for in vivo activity Proc Natl Acad Sci USA 100 2003 11435 11438
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 11435-11438
    • Yi, M.1    Sakai, T.2    Fassler, R.3    Ruoslahti, E.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.