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Volumn 10, Issue 8, 2002, Pages 2511-2526

Design, synthesis and QSAR studies on N-aryl heteroarylisopropanolamines, a new class of non-peptidic HIV-1 protease inhibitors

(7) Di Santo, Roberto a Costi, Roberta a Artico, Marino a Massa, Silvio b Ragno, Rino a Marshall, Garland R c La Colla, Paolo d

a SAPIENZA UNIVERSITY OF ROME (Italy)

b UNIVERSITY OF SIENA (Italy)

c WASHINGTON UNIVERSITY (United States)

d UNIVERSITY OF CAGLIARI (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

BUTANOL; FUNCTIONAL GROUP; INDOLE DERIVATIVE; PROPANOLAMINE DERIVATIVE; PROTEINASE; PROTEINASE INHIBITOR; PYRROLE DERIVATIVE; BUTYLAMINE; MONOISOPROPANOLAMINE;

ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG BINDING; DRUG DESIGN; DRUG POTENCY; DRUG SCREENING; DRUG SYNTHESIS; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME INACTIVATION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; NONHUMAN; PROTEINASE INHIBITION; QUANTITATIVE STRUCTURE ACTIVITY RELATION; T LYMPHOCYTE; CHEMISTRY; DRUG EFFECT; IC 50; SYNTHESIS;

HUMAN IMMUNODEFICIENCY VIRUS 1;

BUTYLAMINES; DRUG DESIGN; HIV PROTEASE; HIV PROTEASE INHIBITORS; HIV-1; HUMANS; INDOLES; INHIBITORY CONCENTRATION 50; PROPANOLAMINES; PYRROLES; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0036286615 PISSN: 09680896 EISSN: None Source Type: Journal
DOI: 10.1016/S0968-0896(02)00119-0 Document Type: Article

Times cited : (42)

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