Transcriptional Regulation of the Ufm1 Conjugation System in Response to Disturbance of the Endoplasmic Reticulum Homeostasis and Inhibition of Vesicle Trafficking

PLoS ONE

Volumn 7, Issue 11, 2012, Pages

  Zhang, Yinghua ^a   Zhang, Mingsheng ^a,b   Wu, Jianchun ^c   Lei, Guohua ^d   Li, Honglin ^a  

^a MEDICAL COLLEGE OF GEORGIA   (United States)

^b HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^c UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^d SOUTHERN MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; PROTEIN C53; PROTEIN LZAP; PROTEIN RCAD; PROTEIN UBA5; PROTEIN UFL1; SHORT HAIRPIN RNA; SMALL INTERFERING RNA; UBIQUITIN; UBIQUITIN FOLD MODIFIER 1; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; X BOX BINDING PROTEIN 1;

ANIMAL CELL; ARTICLE; CELL MIGRATION; CELL VACUOLE; CHROMATIN IMMUNOPRECIPITATION; CONJUGATION; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; FIBROBLAST; HOMEOSTASIS; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; MOUSE; NONHUMAN; PLASMID; PROMOTER REGION; PROTEIN DEFICIENCY; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; RNA ISOLATION; TRANSCRIPTION REGULATION; UPREGULATION; WILD TYPE;

CADHERINS; CELL LINE, TUMOR; DNA-BINDING PROTEINS; ENDOPLASMIC RETICULUM; ENDOPLASMIC RETICULUM STRESS; GENE EXPRESSION REGULATION; GENE SILENCING; HOMEOSTASIS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; NERVE TISSUE PROTEINS; PROTEIN BINDING; PROTEINS; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TRANSPORT VESICLES; UNFOLDED PROTEIN RESPONSE;

ANIMALIA; MUS;

EID: 84869070155     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0048587     Document Type: Article

References (41)

1. Kaufman RJ, (1999) Stress signaling from the lumen of the endoplasmic reticulum: coordination of gene transcriptional and translational controls. Genes Dev 13: 1211-1233.
2. Ron D, Walter P, (2007) Signal integration in the endoplasmic reticulum unfolded protein response. Nat Rev Mol Cell Biol 8: 519-529.
3. Schroder M, Kaufman RJ, (2005) The mammalian unfolded protein response. Annu Rev Biochem 74: 739-789.
4. Cox JS, Shamu CE, Walter P, (1993) Transcriptional induction of genes encoding endoplasmic reticulum resident proteins requires a transmembrane protein kinase. Cell 73: 1197-1206.
5. Mori K, Ma W, Gething MJ, Sambrook J, (1993) A transmembrane protein with a cdc2+/CDC28-related kinase activity is required for signaling from the ER to the nucleus. Cell 74: 743-756.
6. Yoshida H, Matsui T, Yamamoto A, Okada T, Mori K, (2001) XBP1 mRNA is induced by ATF6 and spliced by IRE1 in response to ER stress to produce a highly active transcription factor. Cell 107: 881-891.
7. Calfon M, Zeng H, Urano F, Till JH, Hubbard SR, et al. (2002) IRE1 couples endoplasmic reticulum load to secretory capacity by processing the XBP-1 mRNA. Nature 415: 92-96.
8. Lee K, Tirasophon W, Shen X, Michalak M, Prywes R, et al. (2002) IRE1-mediated unconventional mRNA splicing and S2P-mediated ATF6 cleavage merge to regulate XBP1 in signaling the unfolded protein response. Genes Dev 16: 452-466.
9. Lee AH, Iwakoshi NN, Glimcher LH, (2003) XBP-1 regulates a subset of endoplasmic reticulum resident chaperone genes in the unfolded protein response. Mol Cell Biol 23: 7448-7459.
10. Shi Y, Vattem KM, Sood R, An J, Liang J, et al. (1998) Identification and characterization of pancreatic eukaryotic initiation factor 2 alpha-subunit kinase, PEK, involved in translational control. Mol Cell Biol 18: 7499-7509.
11. Harding HP, Zhang Y, Ron D, (1999) Protein translation and folding are coupled by an endoplasmic-reticulum-resident kinase. Nature 397: 271-274.
12. Haze K, Yoshida H, Yanagi H, Yura T, Mori K, (1999) Mammalian transcription factor ATF6 is synthesized as a transmembrane protein and activated by proteolysis in response to endoplasmic reticulum stress. Mol Biol Cell 10: 3787-3799.
13. Li M, Baumeister P, Roy B, Phan T, Foti D, et al. (2000) ATF6 as a transcription activator of the endoplasmic reticulum stress element: thapsigargin stress-induced changes and synergistic interactions with NF-Y and YY1. Mol Cell Biol 20: 5096-5106.
14. Ye J, Rawson RB, Komuro R, Chen X, Dave UP, et al. (2000) ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs. Mol Cell 6: 1355-1364.
15. Wu J, Rutkowski DT, Dubois M, Swathirajan J, Saunders T, et al. (2007) ATF6alpha optimizes long-term endoplasmic reticulum function to protect cells from chronic stress. Dev Cell 13: 351-364.
16. Yamamoto K, Sato T, Matsui T, Sato M, Okada T, et al. (2007) Transcriptional induction of mammalian ER quality control proteins is mediated by single or combined action of ATF6alpha and XBP1. Dev Cell 13: 365-376.
17. Kerscher O, Felberbaum R, Hochstrasser M, (2006) Modification of proteins by ubiquitin and ubiquitin-like proteins. Annu Rev Cell Dev Biol 22: 159-180.
18. Komatsu M, Chiba T, Tatsumi K, Iemura S, Tanida I, et al. (2004) A novel protein-conjugating system for Ufm1, a ubiquitin-fold modifier. EMBO J 23: 1977-1986.
19. Sasakawa H, Sakata E, Yamaguchi Y, Komatsu M, Tatsumi K, et al. (2006) Solution structure and dynamics of Ufm1, a ubiquitin-fold modifier 1. Biochem Biophys Res Commun 343: 21-26.
20. Kang SH, Kim GR, Seong M, Baek SH, Seol JH, et al. (2007) Two novel ubiquitin-fold modifier 1 (Ufm1)-specific proteases, UfSP1 and UfSP2. J Biol Chem 282: 5256-5262.
21. Tatsumi K, Sou YS, Tada N, Nakamura E, Iemura S, et al. (2010) A novel type of E3 ligase for the Ufm1 conjugation system. J Biol Chem 285: 5417-5427.
22. Wu J, Lei G, Mei M, Tang Y, Li H, (2010) A novel C53/LZAP-interacting protein regulates stability of C53/LZAP and DDRGK domain-containing Protein 1 (DDRGK1) and modulates NF-kappaB signaling. J Biol Chem 285: 15126-15136.
23. Kwon J, Cho HJ, Han SH, No JG, Kwon JY, et al. (2010) A novel LZAP-binding protein, NLBP, inhibits cell invasion. J Biol Chem 285: 12232-12240.
24. Shiwaku H, Yoshimura N, Tamura T, Sone M, Ogishima S, et al. (2010) Suppression of the novel ER protein Maxer by mutant ataxin-1 in Bergman glia contributes to non-cell-autonomous toxicity. EMBO J 29: 2446-2460.
25. Lemaire K, Moura RF, Granvik M, Igoillo-Esteve M, Hohmeier HE, et al. (2011) Ubiquitin fold modifier 1 (UFM1) and its target UFBP1 protect pancreatic beta cells from ER stress-induced apoptosis. PLoS One 6: e18517.
26. Neziri D, Ilhan A, Maj M, Majdic O, Baumgartner-Parzer S, et al. (2010) Cloning and molecular characterization of Dashurin encoded by C20orf116, a PCI-domain containing protein. Biochim Biophys Acta 1800: 430-438.
27. Tatsumi K, Yamamoto-Mukai H, Shimizu R, Waguri S, Sou YS, et al. (2011) The Ufm1-activating enzyme Uba5 is indispensable for erythroid differentiation in mice. Nat Commun 2: 181.
28. Azfer A, Niu J, Rogers LM, Adamski FM, Kolattukudy PE, (2006) Activation of endoplasmic reticulum stress response during the development of ischemic heart disease. Am J Physiol Heart Circ Physiol 291: H1411-1420.
29. Lu H, Yang Y, Allister EM, Wijesekara N, Wheeler MB, (2008) The identification of potential factors associated with the development of type 2 diabetes: a quantitative proteomics approach. Mol Cell Proteomics 7: 1434-1451.
30. Robertson G, Bilenky M, Lin K, He A, Yuen W, et al. (2006) cisRED: a database system for genome-scale computational discovery of regulatory elements. Nucleic Acids Res 34: D68-73.
31. Liou HC, Boothby MR, Finn PW, Davidon R, Nabavi N, et al. (1990) A new member of the leucine zipper class of proteins that binds to the HLA DR alpha promoter. Science 247: 1581-1584.
32. Masaki T, Yoshida M, Noguchi S, (1999) Targeted disruption of CRE-binding factor TREB5 gene leads to cellular necrosis in cardiac myocytes at the embryonic stage. Biochem Biophys Res Commun 261: 350-356.
33. Reimold AM, Etkin A, Clauss I, Perkins A, Friend DS, et al. (2000) An essential role in liver development for transcription factor XBP-1. Genes Dev 14: 152-157.
34. Reimold AM, Iwakoshi NN, Manis J, Vallabhajosyula P, Szomolanyi-Tsuda E, et al. (2001) Plasma cell differentiation requires the transcription factor XBP-1. Nature 412: 300-307.
35. Lee AH, Chu GC, Iwakoshi NN, Glimcher LH, (2005) XBP-1 is required for biogenesis of cellular secretory machinery of exocrine glands. EMBO J 24: 4368-4380.
36. Acosta-Alvear D, Zhou Y, Blais A, Tsikitis M, Lents NH, et al. (2007) XBP1 controls diverse cell type- and condition-specific transcriptional regulatory networks. Mol Cell 27: 53-66.
37. Han D, Lerner AG, Vande Walle L, Upton JP, Xu W, et al. (2009) IRE1alpha kinase activation modes control alternate endoribonuclease outputs to determine divergent cell fates. Cell 138: 562-575.
38. Hollien J, Lin JH, Li H, Stevens N, Walter P, et al. (2009) Regulated Ire1-dependent decay of messenger RNAs in mammalian cells. J Cell Biol 186: 323-331.
39. Oikawa D, Tokuda M, Hosoda A, Iwawaki T, (2010) Identification of a consensus element recognized and cleaved by IRE1 alpha. Nucleic Acids Res 38: 6265-6273.
40. Lee AH, Scapa EF, Cohen DE, Glimcher LH, (2008) Regulation of hepatic lipogenesis by the transcription factor XBP1. Science 320: 1492-1496.
41. Hur KY, So JS, Ruda V, Frank-Kamenetsky M, Fitzgerald K, et al. (2012) IRE1alpha activation protects mice against acetaminophen-induced hepatotoxicity. J Exp Med 209: 307-318.