Hepatoprotective and cytoprotective properties of Hyptis suaveolens against oxidative stress-induced damage by CCl4 and H2O2

Asian Pacific Journal of Tropical Medicine

Volumn 5, Issue 11, 2012, Pages 868-874

  Ghaffari, Hadi ^a   Ghassam, Behrouz Jalali ^a   Prakash, H S ^a  

^a UNIVERSITY OF MYSORE   (India)

Author keywords

Antioxidant enzymes; HepG2 cell line; Hydrogen peroxide; Hyptis suaveolens; Lipid peroxidation; MTT assay

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; ANTIOXIDANT; ASPARTATE AMINOTRANSFERASE; GLUCOCORTICOID RECEPTOR; GLUTATHIONE; GLUTATHIONE TRANSFERASE; HYPTIS SUAVEOLENS EXTRACT; LACTATE DEHYDROGENASE; LIVER PROTECTIVE AGENT; PLANT EXTRACT; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALKALINE PHOSPHATASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CELL PROTECTION; CELL STRAIN HEPG2; CONTROLLED STUDY; DRUG EFFICACY; DRUG MECHANISM; HISTOPATHOLOGY; HYPTIS; HYPTIS SUAVEOLENS; LACTATE DEHYDROGENASE BLOOD LEVEL; LIPID PEROXIDATION; LIVER INJURY; LIVER NECROSIS; LIVER PROTECTION; MALE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT;

ANIMALS; ANTIOXIDANTS; CARBON TETRACHLORIDE; CELL LINE; CELL SURVIVAL; DISEASE MODELS, ANIMAL; DRUG-INDUCED LIVER INJURY; HEPATOCYTES; HISTOCYTOCHEMISTRY; HUMANS; HYDROGEN PEROXIDE; HYPTIS; LIVER; MALE; OXIDATIVE STRESS; PLANT EXTRACTS; RATS; RATS, WISTAR; STAINING AND LABELING; TETRAZOLIUM SALTS; THIAZOLES;

EID: 84869046010     PISSN: 19957645     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1995-7645(12)60162-X     Document Type: Article

References (40)

1. Qian ZJ, Jung WK, Kim SK Free radical scavenging activity of a novel antioxidativepeptide purified from hydrolysate of bullfrog skin, Rana catesbeiana Shaw. Bioresour Technol 2008, 99:1690-1698.
2. Blomhoff R Dietary antioxidants and cardiovascular disease. Curr Opin Lipidol 2005, 16:47-54.
3. Bhathal PS, Rose NR, Mackay IR, Whittingham S Strain differences in mice in carbon tetrachloride-induced liver injury. Br J Exp Pathol 1983, 64:524-533.
4. Vitaglione P, Morisco F, Caporaso N, Fogliano V Dietary antioxidant compounds and liver health. Crit Rev Food Sci Nutr 2004, 44:575-586.
5. Wolf PL Biochemical diagnosis of liver diseases. Clin Biochem 1999, 14:59-90.
6. Gonzalez FJ The molecular biology of cytochrome P450s. Pharmacol Rev 1998, 40:243-288.
7. Brattin WJ, Glende EA, Recknagel RO Pathological mechanisms in carbon tetrachloride hepatotoxicity. Free Radical Bio Med 1985, 1:27-38.
8. Williams AT, Burk RF Carbon tetrachloride hepatotoxicity: an example of free radical-mediated injury. Semin Liver Dis 1990, 10:279-284.
9. Brent JA, Rumack BH Role of free radicals in toxic hepatic injury. II. Are free radicals the cause of toxin-induced liver injury?. J Toxicol Clin Toxicol 1993, 31:173-196.
10. Recknagel RO, Glende RO, Britton RS Free radical damage and lipid peroxidation. Hepatotoxicology 1991, 401-436. CRC Press, Florida. R.G. Meeks (Ed.).
11. Brautbar N, Williams J Industrial solvents and liver toxicity: risk assessment, risk factors and mechanisms. Int J Hyg Environ Health 2002, 205:479-491.
12. Wu D, Zhai Q, Shi X Alcohol-induced oxidative stress and cell responses. J Gastroenterol Hepatol 2006, 21:S26-S29.
13. Loguercio C Federico A. Oxidative stress in viral and alcoholic hepatitis. Free Radical Biol Med 2003, 34:1-10.
14. Chen XL, Kunsch C Induction of cytoprotective genes through Nrf2/antioxidant response element pathway: a new therapeutic approach for the treatment of inflammatory diseases. Curr Pharm Des 2004, 10:879-891.
15. Valko M, Leibfritz D, Moncol J, Cronin MT, Mazur M, Telser J Free radicals and antioxidants in normal physiological functions and human disease. Int J Biochem Cell Biol 2007, 39:44-84.
16. Hivert B, Cerrui C, Camu W Hydrogen peroxide-induced motoneuron apoptosis is prevented by poly ADP ribosyl synthetase inhibitors. Neuroreport 1998, 9:1835-1838.
17. Clement MV, Ponton A, Pervaiz S Apoptosis induced by hydrogen peroxide is mediated by decreased superoxide anion concentration and reduction of intracellular milieu. FEBS Lett 1998, 440:13-18.
18. Kitamura Y, Ota T, Matsuoka Y, Tooyama I, Kimura H, Shimohama S, et al. Hydrogen peroxide-induced apoptosis mediated by P53 protein in glial cells. Glia 1999, 25:154-164.
19. Skaper SD, Floreani M, Negro A, Facci L, Giusti P Neurotrophins rescue cerebellar granule neurons from oxidative stress-mediated apoptotic death: selective involvement of phosphatidylinositol 3-kinase and the mitogen-activated protein kinase pathway. J Neurochem 1998, 70:1859-1868.
20. Shirwaikar A, Shenoy R, Udupa AL, Shetty S Wound healing property of ethanolic extract of leaves of Hyptis suaveolens with supportive role of antioxidant enzymes. Indian J Expt Biol 2003, 41:238-241.
21. Shenoy C, Patil MB, Kumar R Wound healing activity of Hyptis suaveplens (L.) Poit (Lamiaceae). Int J Pharm Tech Res 2009, 1:737-744.
22. Peerzada N Chemical composition of the essential oil of Hyptis suaveolens. Molecules 1997, 2:165-168.
23. Marklund S, Marklund G Involvement of the superoxide anion in the autoxidation of pyrogallol and a convenient assay for superoxide dismutase. Eur J Biochem 1974, 47:469-474.
24. Calberg I, Mannervik B Glutathione reductas. Methods Enzymol 1985, 113:484-490.
25. Warholm M, Guthenberg C, Bahr CV, Mannervik B Glutahtione transferase from human liver. Methods Enzymol 1985, 113:499-504.
26. Ohkawa H, Ohishi N, Yagi K Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem 1979, 95:351-358.
27. Ellman GL Tissue sulfhydryl groups. Arch Biochem Biophys 1959, 82:70-77.
28. Mosmann T Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 1983, 65:55-63.
29. Sturgill MG, Lambert GH Xenobiotic-induced hepatotoxicity: mechanisms of liver injury and methods of monitoring hepatic function. Clin Chem 1997, 43:1512-1526.
30. Valcheva-Kuzmanova S, Borisova P, Galunska B, Belcheva A Hepatoprotective effect of the natural fruit juice from Aronia melanocarpa on carbon tetrachloride-induced acute liver damage in rats. Exp Toxicol Pathol 2004, 156(3):195-201.
31. Thirumalai T, David E, Therasa SV, Elumalai EK Restorative effect of Eclipta alba in CCl4 induced hepatotoxicity in male albino rats. Asian Pac J Trop Dis 2011, 1(4):304-307.
32. 4 induced liver damage in rats. Indian J Exp Biol 2005, 43:437-444.
33. Ozden S, Catalgol B, Gezginci-Oktayoglu S, Arda-Pirincci P, Bolkent S, Alpertunga B Methiocarb-induced oxidative damage following subacute exposure and the protective effects of vitamin E and taurine in rats. Food Chem Toxicol 2009, 47:1676-1684.
34. Reiter RJ, Tan D, Osuna C, Gitto E Actions of melatonin in the reduction of oxidative stress. J Biomed Sci 2000, 7:444-458.
35. 4-induced liver injury in rats. Food Chem Toxicol 2006, 44:1989-1996.
36. Mansour MA Protective effects of thymoquinone and desferrioxamine against hepatotoxicity of carbon tetrachloride in mice. Life Sci 2000, 66:2583-2591.
37. Subash S, Subramanian P Protective effect of morin on lipid peroxidation and lipid profile in ammonium chloride-induced hyperammonemic rats. Asian Pac J Trop Dis 2012, 2(3):103-106.
38. Amresh G, Zeashan H, Gupta RJ, Kant R, Rao CV, Singh PN Gastroprotective effects of ethanolic extract from Cissampelos pareira in experimental animals. J Nat Med 2007, 61:323-328.
39. 4-induced acute liver injury in rats. S Afr J Bot 2007, 73:372-377.
40. Halliwell B Reactive oxygen species and the central nervous system. J Neurochem 1992, 59:1609-1623.