An ac34 deletion mutant of Autographa californica nucleopolyhedrovirus exhibits delayed late gene expression and a lack of virulence in vivo

Journal of Virology

Volumn 86, Issue 19, 2012, Pages 10432-10443

  Cai, Yi ^a   Long, Zhao ^a   Qiu, Jianxiang ^a   Yuan, Meijin ^a   Li, Guanghong ^a   Yang, Kai ^a  

^a SUN YAT SEN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

NUCLEOCAPSID PROTEIN; VIRUS DNA; VIRUS PROTEIN;

38K GENE; AC34 GENE; ARTICLE; AUTOGRAPHA CALIFORNICA; BIOASSAY; CELL NUCLEUS; CONTROLLED STUDY; CYTOPLASM; DELETION MUTANT; GENE DELETION; GENE EXPRESSION; GENE FUNCTION; GENE INACTIVATION; GENE LOCATION; HEMOLYMPH; HUMAN; HUMAN CELL; IN VIVO STUDY; LARVA; LIFE CYCLE; NONHUMAN; P6 9 GENE; POLYHEDROSIS VIRUS; PRIORITY JOURNAL; PROGENY; PROTEIN ASSEMBLY; VIRUS GENE; VIRUS MUTANT; VIRUS REPLICATION; VIRUS VIRULENCE; VP39 GENE; WILD TYPE;

AMINO ACID SEQUENCE; ANIMALS; BACULOVIRIDAE; BIOLOGICAL ASSAY; GENE DELETION; GENE EXPRESSION; GENE EXPRESSION REGULATION; HEMOLYMPH; KINETICS; LARVA; LEPIDOPTERA; MICROSCOPY, ELECTRON, TRANSMISSION; MICROSCOPY, FLUORESCENCE; MOLECULAR SEQUENCE DATA; NUCLEOPOLYHEDROVIRUS; PROMOTER REGIONS, GENETIC; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SEQUENCE HOMOLOGY, AMINO ACID; VIRULENCE;

AUTOGRAPHA CALIFORNICA NUCLEOPOLYHEDROVIRUS; TRICHOPLUSIA NI;

EID: 84869016070     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.00779-12     Document Type: Article

References (68)

1. Ackermann HW, Smirnoff WA. 1983. A morphological investigation of 23 baculoviruses. J. Invertebr. Pathol. 41:269-280.
2. Bai C, et al. 1996. SKP1 connects cell cycle regulators to the ubiquitin proteolysis machinery through a novel motif, the F-box. Cell 86:263-274.
3. Blissard GW, Quant-Russell RL, Rohrmann GF, Beaudreau GS. 1989. Nucleotide sequence, transcriptional mapping, and temporal expression of the gene encoding p39, a major structural protein of the multicapsid nuclear polyhedrosis virus of Orgyia pseudotsugata. Virology 168:354-362.
4. Blissard GW, Rohrmann GF. 1989. Location, sequence, transcriptional mapping, and temporal expression of the gp64 envelope glycoprotein gene of the Orgyia pseudotsugata multicapsid nuclear polyhedrosis virus. Virology 170:537-555.
5. Braunagel SC, Parr R, Belyavskyi M, Summers MD. 1998. Autographa californica nucleopolyhedrovirus infection results in Sf9 cell cycle arrest at G2/M phase. Virology 244:195-211.
6. Braunagel SC, Russell WK, Rosas-Acosta G, Russell DH, Summers MD. 2003. Determination of the protein composition of the occlusion-derived virus of Autographa californica nucleopolyhedrovirus. Proc. Natl. Acad. Sci. U. S. A. 100:9797-9802.
7. Braunagel SC, Summers MD. 1994. Autographa californica nuclear polyhedrosis virus, PDV, and ECV viral envelopes and nucleocapsids: structural proteins, antigens, lipid and fatty acid profiles. Virology 202:315-328.
8. Clarke TE, Clem RJ. 2002. Lack of involvement of haemocytes in the establishment and spread of infection in Spodoptera frugiperda larvae infected with the baculovirus Autographa californica M nucleopolyhedrovirus by intrahaemocoelic injection. J. Gen. Virol. 83:1565-1572.
9. Dai X, Stewart TM, Pathakamuri JA, Li Q, Theilmann DA. 2004. Autographa californica multiple nucleopolyhedrovirus exon0 (orf141), which encodes a RING finger protein, is required for efficient production of budded virus. J. Virol. 78:9633-9644.
10. Davy C, Doorbar J. 2007. G2/M cell cycle arrest in the life cycle of viruses. Virology 368:219-226.
11. Engelhard EK, Volkman LE. 1995. Developmental resistance in fourth instar Trichoplusia ni orally inoculated with Autographa californica M nuclear polyhedrosis virus. Virology 209:384-389.
12. Fan X, McLachlin JR, Weaver RF. 1998. Identification and characterization of a protein kinase-interacting protein encoded by the Autographa californica nuclear polyhedrosis virus. Virology 240:175-182.
13. Fan X, Thirunavukkarasu K, Weaver RF. 1996. Temperature-sensitive mutations in the protein kinase-1 (pk-1) gene of the Autographa californica nuclear polyhedrosis virus that block very late gene expression. Virology 224:1-9.
14. Fang M, Dai X, Theilmann DA. 2007. Autographa californica multiple nucleopolyhedrovirus EXON0 (ORF141) is required for efficient egress of nucleocapsids from the nucleus. J. Virol. 81:9859-9869.
15. Federici BA. 1997. Baculovirus pathogenesis, p 33-59. In Miller LK (ed), The baculoviruses. Plenum Press, New York, NY.
16. Feldman RM, Correll CC, Kaplan KB, Deshaies RJ. 1997. A complex of Cdc4p, Skp1p, and Cdc53p/cullin catalyzes ubiquitination of the phosphorylated CDK inhibitor Sic1p. Cell 91:221-230.
17. Friesen PD. 1997. Regulation of baculovrius early gene expression, p 141-170. In Miller LK (ed), The baculoviruses. Plenum Press, New York, NY.
18. Goldberg AV, Romanowski V, Federici BA, Sciocco de Cap A. 2002. Effects of the Epap granulovirus on its host, Epinotia aporema (Lepidoptera: Tortricidae). J. Invertebr. Pathol. 80:148-159.
19. Goley ED, et al. 2006. Dynamic nuclear actin assembly by Arp2/3 complex and a baculovirus WASP-Like protein. Science 314:464-467.
20. Griffiths CM, et al. 1999. In vitro host range of Autographa californica nucleopolyhedrovirus recombinants lacking functional p35, iap1 or iap2. J. Gen. Virol. 80:1055-1066.
21. Guarino LA, Mistretta TA, Dong W. 2002. Baculovirus lef-12 is not required for viral replication. J. Virol. 76:12032-12043.
22. Hughes PR, Wood HA. 1981. A synchronous peroral technique for the bioassay of insect viruses. J. Invertebr. Pathol. 37:154-159.
23. Ikeda M, Kobayashi M. 1999. Cell-cycle perturbation in Sf9 cells infected with Autographa californica nucleopolyhedrovirus. Virology 258:176-188.
24. Isobe T, et al. 2009. Adenovirus E1A inhibits SCF(Fbw7) ubiquitin ligase. J. Biol. Chem. 284:27766-27779.
25. Jehle JA, et al. 2006. On the classification and nomenclature of baculoviruses: a proposal for revision. Arch. Virol. 151:1257-1266.
26. Jiang SS, et al. 2006. Temporal transcription program of recombinant Autographa californica multiple nucleopolyhedrosis virus. J. Virol. 80: 8989-8999.
27. Ke J, Wang J, Deng R, Wang X. 2008. Autographa californica multiple nucleopolyhedrovirus ac66 is required for the efficient egress of nucleocapsids from the nucleus, general synthesis of preoccluded virions and occlusion body formation. Virology 374:421-431.
28. Keddie BA, Aponte GW, Volkman LE. 1989. The pathway of infection of Autographa californica nuclear polyhedrosis virus in an insect host. Science 243:1728-1730.
29. Lee SY, et al. 1996. A common pathway for p10 and calyx proteins in progressive stages of polyhedron envelope assembly in AcMNPV-infected Spodoptera frugiperda larvae. Arch. Virol. 141:1247-1258.
30. Li L, Harwood SH, Rohrmann GF. 1999. Identification of additional genes that influence baculovirus late gene expression. Virology 255:9-19.
31. Li Y, et al. 2005. vlf-1 deletion brought AcMNPV to defect in nucleocapsid formation. Virus Genes 31:275-284.
32. Lin G, Blissard GW. 2002. Analysis of an Autographa californica multicapsid nucleopolyhedrovirus lef-6-null virus: LEF-6 is not essential for viral replication but appears to accelerate late gene transcription. J. Virol. 76:5503-5514.
33. Lin G, Blissard GW. 2002. Analysis of an Autographa californica nucleopolyhedrovirus lef-11 knockout: LEF-11 is essential for viral DNA replication. J. Virol. 76:2770-2779.
34. Luckow VA, Lee SC, Barry GF, Olins PO. 1993. Efficient generation of infectious recombinant baculoviruses by site-specific transposonmediated insertion of foreign genes into a baculovirus genome propagated in Escherichia coli. J. Virol. 67:4566-4579.
35. Marchler-Bauer A, et al. 2007. CDD: a conserved domain database for interactive domain family analysis. Nucleic Acids Res. 35:D237-D240.
36. Marek M, Merten OW, Galibert L, Vlak JM, van Oers MM. 2011. Baculovirus VP80 protein and the F-actin cytoskeleton interact connecting the viral replication factory with the nuclear periphery. J. Virol. 85: 5350-5362.
37. McLachlin JR, Yang S, Miller LK. 1998. A baculovirus mutant defective in PKIP, a protein which interacts with a virus-encoded protein kinase. Virology 246:379-391.
38. Nakayama KI, Nakayama K. 2005. Regulation of the cell cycle by SCFtype ubiquitin ligases. Semin. Cell Dev. Biol. 16:323-333.
39. Ohkawa T, Volkman LE, Welch MD. 2010. Actin-based motility drives baculovirus transit to the nucleus and cell surface. J. Cell Biol. 190:187-195.
40. Passarelli AL, Guarino LA. 2007. Baculovirus late and very late gene regulation. Curr. Drug Targets 8:1103-1115.
41. Possee RD, et al. 1991. Nucleotide sequence of the Autographa californica nuclear polyhedrosis 9.4 kbp EcoRI-I and -R (polyhedrin gene) region. Virology 185:229-241.
42. Rapp JC, Wilson JA, Miller LK. 1998. Nineteen baculovirus open reading frames, including LEF-12, support late gene expression. J. Virol. 72: 10197-10206.
43. Rivkin H, et al. 2006. Response of immunocompetent and immunosuppressed Spodoptera littoralis larvae to baculovirus infection. J. Gen. Virol. 87:2217-2225.
44. Rohrmann GF. 2011. Baculovirus molecular biology. National Library of Medicine, National Center for Biotechology Information, Bethesda, MD.
45. Russell RL, Funk CJ, Rohrmann GF. 1997. Association of a baculovirus-encoded protein with the capsid basal region. Virology 227:142-152.
46. Saha A, et al. 2011. Epstein-Barr virus nuclear antigen 3C facilitates G1-S transition by stabilizing and enhancing the function of cyclin D1. PLoS Pathog. 7:e1001275. doi:10.1371/journal.ppat.1001275.
47. Saito T, Dojima T, Toriyama M, Park EY. 2002. The effect of cell cycle on GFPuv gene expression in the baculovirus expression system. J. Biotechnol. 93:121-129.
48. Skowyra D, Craig KL, Tyers M, Elledge SJ, Harper JW. 1997. F-box proteins are receptors that recruit phosphorylated substrates to the SCF ubiquitin-ligase complex. Cell 91:209-219.
49. Slack J, Arif B. 2007. The Baculoviruses occlusion-derived virus: virion structure and function. Adv. Virus Res. 69:99-165.
50. Soding J. 2005. Protein homology detection by HMM-HMM comparison. Bioinformatics 21:951-960.
51. Stewart TM, Huijskens I, Willis LG, Theilmann DA. 2005. The Autographa californica multiple nucleopolyhedrovirus ie0-ie1 gene complex is essential for wild-type virus replication, but either IE0 or IE1 can support virus growth. J. Virol. 79:4619-4629.
52. Thiem SM. 2009. Baculovirus genes affecting host function. In Vitro Cell Dev. Biol. Anim. 45:111-126.
53. Trudeau D, Washburn JO, Volkman LE. 2001. Central role of hemocytes in Autographa californica M nucleopolyhedrovirus pathogenesis in Heliothis virescens and Helicoverpa zea. J. Virol. 75:996-1003.
54. Vanarsdall AL, Okano K, Rohrmann GF. 2005. Characterization of the replication of a baculovirus mutant lacking the DNA polymerase gene. Virology 331:175-180.
55. Wang M, et al. 2010. Specificity of baculovirus P6.9 basic DNA-binding proteins and critical role of the C terminus in virion formation. J. Virol. 84:8821-8828.
56. Wang R, et al. 2010. Proteomics of the Autographa californica nucleopolyhedrovirus budded virions. J. Virol. 84:7233-7242.
57. Washburn JO, Kirkpatrick BA, Volkman LE. 1996. Insect protection against viruses. Nature 383:767.
58. Washburn JO, Lyons EH, Haas-Stapleton EJ, Volkman LE. 1999. Multiple nucleocapsid packaging of Autographa californica nucleopolyhedrovirus accelerates the onset of systemic infection in Trichoplusia ni. J. Virol. 73:411-416.
59. Welcker M, Clurman BE. 2005. The SV40 large T antigen contains a decoy phosphodegron that mediates its interactions with Fbw7/hCdc4. J. Biol. Chem. 280:7654-7658.
60. Whitt MA, Manning JS. 1988. A phosphorylated 34-kDa protein and a subpopulation of polyhedrin are thiol linked to the carbohydrate layer surrounding a baculovirus occlusion body. Virology 163:33-42.
61. Williams GV, Faulkner P. 1997. Cytological changes and viral morphogenesis during baculovirus infection, p 61-107. In Miller LK (ed), The baculoviruses. Plenum Press, New York, NY.
62. Wilson ME, Mainprize TH, Friesen PD, Miller LK. 1987. Location, transcription, and sequence of a baculovirus gene encoding a small arginine-rich polypeptide. J. Virol. 61:661-666.
63. Wu CP, et al. 2010. Autographa californica multiple nucleopolyhedrovirus LEF-2 is a capsid protein required for amplification but not initiation of viral DNA replication. J. Virol. 84:5015-5024.
64. Wu W, et al. 2006. Autographa californica multiple nucleopolyhedrovirus nucleocapsid assembly is interrupted upon deletion of the 38K gene. J. Virol. 80:11475-11485.
65. Yamagishi J, Burnett ED, Harwood SH, Blissard GW. 2007. The AcMNPV pp31 gene is not essential for productive AcMNPV replication or late gene transcription but appears to increase levels of most viral transcripts. Virology 365:34-47.
66. Yu Q, Lin T, Feng G, Yang K, Pang Y. 2008. Functional analysis of the putative antiapoptotic genes, p49 and iap4,ofSpodoptera litura nucleopolyhedrovirus with RNAi. J. Gen. Virol. 89:1873-1880.
67. Yuan M, et al. 2011. Identification of Autographa californica nucleopolyhedrovirus ac93 as a core gene and its requirement for intranuclear microvesicle formation and nuclear egress of nucleocapsids. J. Virol. 85: 11664-11674.
68. Zheng N, et al. 2002. Structure of the Cul1-Rbx1-Skp1-F boxSkp2 SCF ubiquitin ligase complex. Nature 416:703-709.