Neuroprotective tri- and tetracyclic BChE inhibitors releasing reversible inhibitors upon carbamate transfer

ACS Medicinal Chemistry Letters

Volumn 3, Issue 11, 2012, Pages 914-919

  Darras, Fouad H ^a   Kling, Beata ^a   Heilmann, Jörg ^a   Decker, Michael ^a  

^a UNIVERSITY OF REGENSBURG   (Germany)

Author keywords

Alzheimer's disease; butyrylcholinesterase; carbamates; neuroprotection

Indexed keywords

ANTIOXIDANT; CARBAMIC ACID; CHOLINESTERASE; CHOLINESTERASE INHIBITOR; NEUROPROTECTIVE AGENT; REACTIVE OXYGEN METABOLITE;

ALZHEIMER DISEASE; ANIMAL CELL; ANTIOXIDANT ACTIVITY; ARTICLE; CARBAMOYLATION; CHOLINESTERASE INHIBITION; CONTROLLED STUDY; DRUG DESIGN; DRUG IDENTIFICATION; DRUG POTENCY; DRUG SELECTIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVE SITE; ENZYME INACTIVATION; HIPPOCAMPUS; IC 50; MOUSE; NERVE CELL CULTURE; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS;

EID: 84868708721     PISSN: None     EISSN: 19485875     Source Type: Journal    
DOI: 10.1021/ml3001825     Document Type: Article

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